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The map label for this gene is panE [H]

Identifier: 209694510

GI number: 209694510

Start: 1039668

End: 1040567

Strand: Reverse

Name: panE [H]

Synonym: VSAL_I0942

Alternate gene names: 209694510

Gene position: 1040567-1039668 (Counterclockwise)

Preceding gene: 209694511

Following gene: 209694509

Centisome position: 31.29

GC content: 38.11

Gene sequence:

>900_bases
ATGAGTGTGAATATCACCATTCTTGGCCCTGGAGCCGTAGGTTCATTGTGGGCATGTTATTTTCAAAAAGCAGGTCATAA
CGTCTCTTTATGGACAAGAAATACCGTCCCTTCAGATATATCACTGTCTTTGTCTGCACAAGAAAACTCATCTCATCAAT
TCTCTTGTGACAATCCTGAATCATTACCCCATTGTGATTTACTTTTTATTACAGTCAAAGCATGGCAAGTTAACCTCGCC
CTTCTTCCGTTACTTCCTCTTTTATCAAAAGAGACCATATTGCTTTTCATGCATAATGGTATGGGTGCAATTGATACCAT
GGAAAATGAACTAACGCATCACCCTATACTGCAAGCCACAACGACGCACGCGGCACTAAAACACAATAAAAACCACGTAG
AGCATACTGGTGTAGGTGCAACGGTTATTGGTCCATTTAACTCATTAGGTAAGCAATGCTTATTTATGAAAGAGGTACTC
GATCACTCTCTTACTAATGTTGAATGGAATGACTCAATCCAACCCGCACTTTGGAAAAAGCTCGCCATTAACTGCGCAAT
AAACCCATTAACCGCAATCCATCAATGCAAAAATGGCGATCTACTGCATCCTAAATTGCATAGTGATGTTTTAACTATCT
GTAATGAAGTCTATCTGGTGCTTGAAAAAAATCACAGTGATTGGTCTTTAAAGGAATTAATCACCACCGTTAATCAAGTG
ATTACCGCAACGTCTGTAAATTACTCGTCAATGAATCGAGATTGTTTTTATCAACGAAAAAGTGAAATCGACTTCATTAC
TGGTTATCTTTTACAGCAAGCCAAGAAACATCGCATTTCAATCCCAACCAACCAAGCCTTGTATAATAAAATTAAACAAT
TAGAAGAGTACTTATTATGA

Upstream 100 bases:

>100_bases
TTAAGCTAGAATCTCGATTTTATTAAGGCGCTCATCATGAGCGCCTTTGTTTTTTCCAGTAAACCCATTACACTACTTTC
ATTATTTATCTTCGACGGAT

Downstream 100 bases:

>100_bases
CCACCAATATTCTAGTCTGTCTTGCTCCCGGAACGGAAGAACTTGAAGCAATTACCGTTATTGATATTTTAGAGCGCGCT
AAATTTAAGGTCACCATTGC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSVNITILGPGAVGSLWACYFQKAGHNVSLWTRNTVPSDISLSLSAQENSSHQFSCDNPESLPHCDLLFITVKAWQVNLA
LLPLLPLLSKETILLFMHNGMGAIDTMENELTHHPILQATTTHAALKHNKNHVEHTGVGATVIGPFNSLGKQCLFMKEVL
DHSLTNVEWNDSIQPALWKKLAINCAINPLTAIHQCKNGDLLHPKLHSDVLTICNEVYLVLEKNHSDWSLKELITTVNQV
ITATSVNYSSMNRDCFYQRKSEIDFITGYLLQQAKKHRISIPTNQALYNKIKQLEEYLL

Sequences:

>Translated_299_residues
MSVNITILGPGAVGSLWACYFQKAGHNVSLWTRNTVPSDISLSLSAQENSSHQFSCDNPESLPHCDLLFITVKAWQVNLA
LLPLLPLLSKETILLFMHNGMGAIDTMENELTHHPILQATTTHAALKHNKNHVEHTGVGATVIGPFNSLGKQCLFMKEVL
DHSLTNVEWNDSIQPALWKKLAINCAINPLTAIHQCKNGDLLHPKLHSDVLTICNEVYLVLEKNHSDWSLKELITTVNQV
ITATSVNYSSMNRDCFYQRKSEIDFITGYLLQQAKKHRISIPTNQALYNKIKQLEEYLL
>Mature_298_residues
SVNITILGPGAVGSLWACYFQKAGHNVSLWTRNTVPSDISLSLSAQENSSHQFSCDNPESLPHCDLLFITVKAWQVNLAL
LPLLPLLSKETILLFMHNGMGAIDTMENELTHHPILQATTTHAALKHNKNHVEHTGVGATVIGPFNSLGKQCLFMKEVLD
HSLTNVEWNDSIQPALWKKLAINCAINPLTAIHQCKNGDLLHPKLHSDVLTICNEVYLVLEKNHSDWSLKELITTVNQVI
TATSVNYSSMNRDCFYQRKSEIDFITGYLLQQAKKHRISIPTNQALYNKIKQLEEYLL

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=299, Percent_Identity=39.7993311036789, Blast_Score=203, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33529; Mature: 33398

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNITILGPGAVGSLWACYFQKAGHNVSLWTRNTVPSDISLSLSAQENSSHQFSCDNPE
CEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCC
SLPHCDLLFITVKAWQVNLALLPLLPLLSKETILLFMHNGMGAIDTMENELTHHPILQAT
CCCCCEEEEEEEEEEEEEHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCHHHH
TTHAALKHNKNHVEHTGVGATVIGPFNSLGKQCLFMKEVLDHSLTNVEWNDSIQPALWKK
HHHHHHHCCCCCCEECCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LAINCAINPLTAIHQCKNGDLLHPKLHSDVLTICNEVYLVLEKNHSDWSLKELITTVNQV
HHHHCCCCHHHHHHHCCCCCEECCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHH
ITATSVNYSSMNRDCFYQRKSEIDFITGYLLQQAKKHRISIPTNQALYNKIKQLEEYLL
HHHCCCCHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVNITILGPGAVGSLWACYFQKAGHNVSLWTRNTVPSDISLSLSAQENSSHQFSCDNPE
EEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCC
SLPHCDLLFITVKAWQVNLALLPLLPLLSKETILLFMHNGMGAIDTMENELTHHPILQAT
CCCCCEEEEEEEEEEEEEHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCHHHH
TTHAALKHNKNHVEHTGVGATVIGPFNSLGKQCLFMKEVLDHSLTNVEWNDSIQPALWKK
HHHHHHHCCCCCCEECCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LAINCAINPLTAIHQCKNGDLLHPKLHSDVLTICNEVYLVLEKNHSDWSLKELITTVNQV
HHHHCCCCHHHHHHHCCCCCEECCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHH
ITATSVNYSSMNRDCFYQRKSEIDFITGYLLQQAKKHRISIPTNQALYNKIKQLEEYLL
HHHCCCCHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]