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The map label for this gene is thiJ [H]

Identifier: 209694509

GI number: 209694509

Start: 1039081

End: 1039671

Strand: Reverse

Name: thiJ [H]

Synonym: VSAL_I0941

Alternate gene names: 209694509

Gene position: 1039671-1039081 (Counterclockwise)

Preceding gene: 209694510

Following gene: 209694507

Centisome position: 31.27

GC content: 41.62

Gene sequence:

>591_bases
ATGACCACCAATATTCTAGTCTGTCTTGCTCCCGGAACGGAAGAACTTGAAGCAATTACCGTTATTGATATTTTAGAGCG
CGCTAAATTTAAGGTCACCATTGCTAGTACGGCCTTTGATGGTTCATTAACAATGAAAGCAGCTCAACGAGTAACACTAA
CGGCAGACGTAAAATTAGTCGATGTGGCTGATGAAGAATTTGACTGTATTGTCCTTCCTGGTGGATTAAAAGGCTCTGAA
AACTTCCGCGACAGTACATTATTAATTGAGCTACTAAAACAACAAAAAGACGATGGTAAATGGGTTGCAGCAATTTGCGC
AGCGCCTGCCATCGTACTCCAACATCATAATATTTATCCTGCCGCTTTAATGACGTGTTACCCAGCACTAATGCACCACA
TCCCAGAACAAAATCGCCGAGTAAAACGTGTGTTTACCGATGTACTAAATAACCTAATTACAAGTCAAGGCCCGGGTTCT
GCACTGGAGTTTGCAATGGAAATTGTGACGCAATTTGGTGGTAAAGAACTGACCGCTCAATTAGCGACTGACTTAGTAAC
ACTACCAACATTAAATTACCATCAAGCCTAA

Upstream 100 bases:

>100_bases
TTACTGGTTATCTTTTACAGCAAGCCAAGAAACATCGCATTTCAATCCCAACCAACCAAGCCTTGTATAATAAAATTAAA
CAATTAGAAGAGTACTTATT

Downstream 100 bases:

>100_bases
TCGGATGCTTGAAATCCCAATACCAAATAAAATTGCCATTGGGATTTCCTTCTTTTTTCTTTCTCTACACTATGATACGG
TTTCTTTTCTCGTCACTATG

Product: protein ThiJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTTNILVCLAPGTEELEAITVIDILERAKFKVTIASTAFDGSLTMKAAQRVTLTADVKLVDVADEEFDCIVLPGGLKGSE
NFRDSTLLIELLKQQKDDGKWVAAICAAPAIVLQHHNIYPAALMTCYPALMHHIPEQNRRVKRVFTDVLNNLITSQGPGS
ALEFAMEIVTQFGGKELTAQLATDLVTLPTLNYHQA

Sequences:

>Translated_196_residues
MTTNILVCLAPGTEELEAITVIDILERAKFKVTIASTAFDGSLTMKAAQRVTLTADVKLVDVADEEFDCIVLPGGLKGSE
NFRDSTLLIELLKQQKDDGKWVAAICAAPAIVLQHHNIYPAALMTCYPALMHHIPEQNRRVKRVFTDVLNNLITSQGPGS
ALEFAMEIVTQFGGKELTAQLATDLVTLPTLNYHQA
>Mature_195_residues
TTNILVCLAPGTEELEAITVIDILERAKFKVTIASTAFDGSLTMKAAQRVTLTADVKLVDVADEEFDCIVLPGGLKGSEN
FRDSTLLIELLKQQKDDGKWVAAICAAPAIVLQHHNIYPAALMTCYPALMHHIPEQNRRVKRVFTDVLNNLITSQGPGSA
LEFAMEIVTQFGGKELTAQLATDLVTLPTLNYHQA

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=193, Percent_Identity=36.2694300518135, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI31543380, Length=193, Percent_Identity=36.2694300518135, Blast_Score=107, Evalue=8e-24,
Organism=Escherichia coli, GI87081736, Length=196, Percent_Identity=50, Blast_Score=189, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17531319, Length=179, Percent_Identity=35.7541899441341, Blast_Score=113, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17558714, Length=168, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571932, Length=188, Percent_Identity=40.9574468085106, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24653499, Length=182, Percent_Identity=34.6153846153846, Blast_Score=100, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 21392; Mature: 21261

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNILVCLAPGTEELEAITVIDILERAKFKVTIASTAFDGSLTMKAAQRVTLTADVKLV
CCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEEEEEECCCCEEEHHHHEEEEEECEEEE
DVADEEFDCIVLPGGLKGSENFRDSTLLIELLKQQKDDGKWVAAICAAPAIVLQHHNIYP
EECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEECCCCCH
AALMTCYPALMHHIPEQNRRVKRVFTDVLNNLITSQGPGSALEFAMEIVTQFGGKELTAQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHH
LATDLVTLPTLNYHQA
HHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTNILVCLAPGTEELEAITVIDILERAKFKVTIASTAFDGSLTMKAAQRVTLTADVKLV
CCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEEEEEECCCCEEEHHHHEEEEEECEEEE
DVADEEFDCIVLPGGLKGSENFRDSTLLIELLKQQKDDGKWVAAICAAPAIVLQHHNIYP
EECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEECCCCCH
AALMTCYPALMHHIPEQNRRVKRVFTDVLNNLITSQGPGSALEFAMEIVTQFGGKELTAQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHH
LATDLVTLPTLNYHQA
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]