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The map label for this gene is sucC

Identifier: 209694427

GI number: 209694427

Start: 944824

End: 945990

Strand: Direct

Name: sucC

Synonym: VSAL_I0848

Alternate gene names: 209694427

Gene position: 944824-945990 (Clockwise)

Preceding gene: 209694426

Following gene: 209694428

Centisome position: 28.41

GC content: 43.87

Gene sequence:

>1167_bases
ATGAACCTACATGAATATCAAGCAAAGCAACTCTTTGCAGAATACGGCCTTCCTGTACCTGAAGGTTATGCTTGTGATAC
CGCTCAAGAGGCTTTTGAAGCTGCTGGACGTATTAGCACTGCGAAAAAAGTGGTTAAGTGTCAAGTCCACGCTGGTGGTC
GCGGTAAAGCGGGCGGTGTTGAACTGCATGACACAAAAGAAGGCGTTAAAGAATTCGCTCAAAAGTGGTTAGGTAAAAAC
CTAGTGACTTTCCAAACAGACGCTAAGGGTCAACCAGTCACAAAAGTATTGGTTGAAGAAGCGTCAAATATTGCAAATGA
ATTATACCTAGGTGCGGTTGTTGACCGTGCTACGCGTCGTATCGTGTTCATGGCATCGACTGAAGGTGGTGTGGATATTG
AGAAGATTGCTGAAGAAACTCCAGAGTTAATTCACCAAGCGGCGATTGATCCATTAGTTGGTCCTCAAGCTTTCCAAGGC
CGTGAATTAGCCTTTAAACTTGGTCTTGAAGGCGATCAAATTAAGCAATTCGTTAAGATCTTTCTAGGTCTTGGCAACAT
GTTTGCTCAGTATGATTTAGCGCTACTTGAAATTAACCCACTTGTGGTGACGGCAGAAGGTAACCTTCTGTGTTTAGATG
GTAAAATTAACATTGATTCTAATGCTATGTACCGTCAACCAAAACTGCGTGAAATGCATGATCCATCTCAAGAAGATGAG
CGCGAAGCACATGCAGCACAATGGGAATTAAACTACGTTGCCCTAGATGGTAGCATTGGTTGTATGGTAAATGGTGCAGG
CCTTGCTATGGGCACAATGGATATCGTGAATCTACACGGTGGCCAACCTGCTAACTTCCTAGATGTTGGCGGCGGTGCAA
CAAAAGAACGTGTAACAGAAGCCTTTAAGATCATCTTATCAGACAGCAATGTAAAAGCGGTTTTGGTTAACATCTTTGGT
GGTATTGTTCGCTGTGACCTTATTGCTGATGGCATTATTGGTGCGGTTGAAGAAGTGGGTGTAAAAGTGCCTGTTGTTGT
TCGCCTTGAAGGTAATAACGCACCACTAGGGTCACAAAAACTGGCTGAAAGTGGCCTAAATATCATTGCGGCTACTTCAT
TAACTGAAGCAGCTGAAAAAGTTGTTGCTGCTGCGGAGGGCAAATAA

Upstream 100 bases:

>100_bases
ATTCAACTTCATTATTGGATAAAAATAGAAAGATGCCTTAGAGCGTCTTAGGACATTAAAAATTCCCATTAAAGGGAATA
ACTAAAATGGATAGAACATA

Downstream 100 bases:

>100_bases
TGTCTGTACTAATTAATAAAGATACAAAAGTTATCTGCCAAGGTTTCACTGGTGGCCAAGGAACATTCCACTCAGAGCAA
GCAATTGATTACGGAACAAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKQLFAEYGLPVPEGYACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTFQTDAKGQPVTKVLVEEASNIANELYLGAVVDRATRRIVFMASTEGGVDIEKIAEETPELIHQAAIDPLVGPQAFQG
RELAFKLGLEGDQIKQFVKIFLGLGNMFAQYDLALLEINPLVVTAEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
REAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTEAFKIILSDSNVKAVLVNIFG
GIVRCDLIADGIIGAVEEVGVKVPVVVRLEGNNAPLGSQKLAESGLNIIAATSLTEAAEKVVAAAEGK

Sequences:

>Translated_388_residues
MNLHEYQAKQLFAEYGLPVPEGYACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTFQTDAKGQPVTKVLVEEASNIANELYLGAVVDRATRRIVFMASTEGGVDIEKIAEETPELIHQAAIDPLVGPQAFQG
RELAFKLGLEGDQIKQFVKIFLGLGNMFAQYDLALLEINPLVVTAEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
REAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTEAFKIILSDSNVKAVLVNIFG
GIVRCDLIADGIIGAVEEVGVKVPVVVRLEGNNAPLGSQKLAESGLNIIAATSLTEAAEKVVAAAEGK
>Mature_388_residues
MNLHEYQAKQLFAEYGLPVPEGYACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTFQTDAKGQPVTKVLVEEASNIANELYLGAVVDRATRRIVFMASTEGGVDIEKIAEETPELIHQAAIDPLVGPQAFQG
RELAFKLGLEGDQIKQFVKIFLGLGNMFAQYDLALLEINPLVVTAEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
REAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTEAFKIILSDSNVKAVLVNIFG
GIVRCDLIADGIIGAVEEVGVKVPVVVRLEGNNAPLGSQKLAESGLNIIAATSLTEAAEKVVAAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=46.0559796437659, Blast_Score=346, Evalue=3e-95,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.3864229765013, Blast_Score=313, Evalue=3e-85,
Organism=Homo sapiens, GI294862256, Length=358, Percent_Identity=45.2513966480447, Blast_Score=303, Evalue=2e-82,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=75.7731958762887, Blast_Score=593, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=46.3917525773196, Blast_Score=322, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=43.0025445292621, Blast_Score=309, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=41.3265306122449, Blast_Score=315, Evalue=1e-86,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=43.5114503816794, Blast_Score=307, Evalue=9e-84,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=43.5114503816794, Blast_Score=307, Evalue=9e-84,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=43.6548223350254, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=43.6548223350254, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI21356231, Length=395, Percent_Identity=42.7848101265823, Blast_Score=297, Evalue=7e-81,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_ALISL (B6EHV6)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262355.1
- GeneID:   6989264
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0848
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41422; Mature: 41422

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQLFAEYGLPVPEGYACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHEEEEEEEECCCCCCCCCE
ELHDTKEGVKEFAQKWLGKNLVTFQTDAKGQPVTKVLVEEASNIANELYLGAVVDRATRR
EECCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IVFMASTEGGVDIEKIAEETPELIHQAAIDPLVGPQAFQGRELAFKLGLEGDQIKQFVKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FLGLGNMFAQYDLALLEINPLVVTAEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
HHHHHHHHHHHCEEEEEECCEEEEECCCEEEECCEEEECCCCCCCCCCHHHHCCCCCHHH
REAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVKVPVVVRLEGNNAPLGSQK
HHHHEECCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHH
LAESGLNIIAATSLTEAAEKVVAAAEGK
HHHCCCCEEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLHEYQAKQLFAEYGLPVPEGYACDTAQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHEEEEEEEECCCCCCCCCE
ELHDTKEGVKEFAQKWLGKNLVTFQTDAKGQPVTKVLVEEASNIANELYLGAVVDRATRR
EECCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IVFMASTEGGVDIEKIAEETPELIHQAAIDPLVGPQAFQGRELAFKLGLEGDQIKQFVKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FLGLGNMFAQYDLALLEINPLVVTAEGNLLCLDGKINIDSNAMYRQPKLREMHDPSQEDE
HHHHHHHHHHHCEEEEEECCEEEEECCCEEEECCEEEECCCCCCCCCCHHHHCCCCCHHH
REAHAAQWELNYVALDGSIGCMVNGAGLAMGTMDIVNLHGGQPANFLDVGGGATKERVTE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVKVPVVVRLEGNNAPLGSQK
HHHHEECCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHH
LAESGLNIIAATSLTEAAEKVVAAAEGK
HHHCCCCEEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA