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The map label for this gene is pgm [H]

Identifier: 209694418

GI number: 209694418

Start: 932983

End: 934629

Strand: Direct

Name: pgm [H]

Synonym: VSAL_I0839

Alternate gene names: 209694418

Gene position: 932983-934629 (Clockwise)

Preceding gene: 209694417

Following gene: 209694419

Centisome position: 28.06

GC content: 39.22

Gene sequence:

>1647_bases
ATGGCTATACATCCTCGCGCTGGGCAAAAAGCTCAGCAAGAAGATTTACACAATATCCCAGTATTAGTTGCTAATTATTT
TTTATTAGAGCCAAACCCAGCTAATGCCGATCAGAAAGTGCAATTTGGTACTTCTGGACACCGTGGAACGGCGGATAAAT
CAACGTTTAATCAGCATCATATTTGGGCAATTGCTCAAGCGGTTGTTGATGTTCGTAAAGCGAATGGAGTGACTGGTCCT
CTGTTTTTAGGGAAAGATACTCACGCATTATCTGAACCTGCATTTACGTCTGCAATTGAAGTATTTGTTGCAAATGGCGT
TGAAGTTATTATTCAAGAGAATAATGGCTACACTCCGACCCCTGGTATTTCGCATGCAATTTTAACGCATAATGTTAAAT
TTGATGAGAAAGCTGATGGTATTGTGATTACACCTTCTCATAACCCACCTCAAGATGGCGGCATTAAATATAATCCTGTT
CATGGAGGACCGGCAGAAGGTGAGCTGACGACAGCCATTGAAAATCGTGCGAATCAATTGATTGCGAATGAATTAAAAGA
AGTTAAACGCGTTTCTATAACAGAGGCAATGGCTTCTGATCTTGTTAAGCAAATTGACTTAGTTCAACCGTATATTGATG
ATCTGAAAAATGTGATTAATATTGAAGCGATTCAAAAAGCAAATTTAAAATTAGGTGTGGATCCACTTGGCGGTTCTGGC
ATTGAATATTGGCGTCAAATTGGTCAGGCGTTTGAACTTGATTTGACTCTTGTGAGTGAAGCTATCGATCCGTCATTCCA
GTTTATGTCGTTAGATAAAGACGGTGTAGTTCGTATGGACTGTTCTTCACCTTATGCAATGGCTGGATTATTATCATTAA
AAGATGATTATGATTTAGCGTTCGGTAATGATCCTGATTATGATCGCCATGGTATTGTTACACCATCAGGACTAATGAAC
CCAAACCATTACCTTGCAGTATGTATTGATTATTTATATCAAAATCGACCTCAGTGGAAAAGCGAAGTTGCTGTAGGTAA
AACTCTCGTTTCTTCAGCTATTATTGATAAGGTTGTGGCTGATTTAGGCCGTGATTTATGTGAAGTTCCTGTTGGTTTTA
AGTGGTTTGTTGATGGTTTATACAATGGGACACTAGGCTTTGGTGGTGAAGAAAGTGCAGGTGCTTCTTTCTTACGTTTT
GATGGTACACCATGGTCAACAGATAAAGATGGTATTCTTTTGTGTCTACTTGCTGCTGAAATTACAGCAATAACTGGTAT
GAACCCGCAAGAATATTATAATAAACTTGCTGCTCAACACGGTGAATCAAGTTATAACCGTATTCAAGCGGTTGCGAATA
AAGAACAAAAAGCGGTATTAAGTAAACTCTCTCCAGAGATGGTGTCTGCAACAACATTAGCAGGTGATGAGATTACTGCA
CGTTTAACGCATGCTCCTGGTAACGGTGCTGCGATTGGTGGTTTGAAAGTAACAACGGCGAATGGTTGGTTTGCTGCACG
CCCATCTGGAACTGAAGAGATTTATAAAATTTACTGCGAAAGTTTTAAAGGTGCTGATCATTTGGCATTGATTGAGCAAG
AAGCACAAGAAATTGTAAGTAATGTATTTAAAGACGCTGGATTATAG

Upstream 100 bases:

>100_bases
ACGTATGGGTTTCCAACATGACTTAACAGAAAAAGTGTGCGCGGCGATTTAATTTTTTGAGTTAGCACTCAAATCATAAT
TTGTCACAAGGAATCGTCAA

Downstream 100 bases:

>100_bases
TGGTCTAGTATAATTTCAGTAAAATGTTAATAAAAAAAGCAGCGCATGTCGCTGCTTTTTTTATTTTAAATATAGGGACG
TGATAGTGAATAATTTTCAG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MAIHPRAGQKAQQEDLHNIPVLVANYFLLEPNPANADQKVQFGTSGHRGTADKSTFNQHHIWAIAQAVVDVRKANGVTGP
LFLGKDTHALSEPAFTSAIEVFVANGVEVIIQENNGYTPTPGISHAILTHNVKFDEKADGIVITPSHNPPQDGGIKYNPV
HGGPAEGELTTAIENRANQLIANELKEVKRVSITEAMASDLVKQIDLVQPYIDDLKNVINIEAIQKANLKLGVDPLGGSG
IEYWRQIGQAFELDLTLVSEAIDPSFQFMSLDKDGVVRMDCSSPYAMAGLLSLKDDYDLAFGNDPDYDRHGIVTPSGLMN
PNHYLAVCIDYLYQNRPQWKSEVAVGKTLVSSAIIDKVVADLGRDLCEVPVGFKWFVDGLYNGTLGFGGEESAGASFLRF
DGTPWSTDKDGILLCLLAAEITAITGMNPQEYYNKLAAQHGESSYNRIQAVANKEQKAVLSKLSPEMVSATTLAGDEITA
RLTHAPGNGAAIGGLKVTTANGWFAARPSGTEEIYKIYCESFKGADHLALIEQEAQEIVSNVFKDAGL

Sequences:

>Translated_548_residues
MAIHPRAGQKAQQEDLHNIPVLVANYFLLEPNPANADQKVQFGTSGHRGTADKSTFNQHHIWAIAQAVVDVRKANGVTGP
LFLGKDTHALSEPAFTSAIEVFVANGVEVIIQENNGYTPTPGISHAILTHNVKFDEKADGIVITPSHNPPQDGGIKYNPV
HGGPAEGELTTAIENRANQLIANELKEVKRVSITEAMASDLVKQIDLVQPYIDDLKNVINIEAIQKANLKLGVDPLGGSG
IEYWRQIGQAFELDLTLVSEAIDPSFQFMSLDKDGVVRMDCSSPYAMAGLLSLKDDYDLAFGNDPDYDRHGIVTPSGLMN
PNHYLAVCIDYLYQNRPQWKSEVAVGKTLVSSAIIDKVVADLGRDLCEVPVGFKWFVDGLYNGTLGFGGEESAGASFLRF
DGTPWSTDKDGILLCLLAAEITAITGMNPQEYYNKLAAQHGESSYNRIQAVANKEQKAVLSKLSPEMVSATTLAGDEITA
RLTHAPGNGAAIGGLKVTTANGWFAARPSGTEEIYKIYCESFKGADHLALIEQEAQEIVSNVFKDAGL
>Mature_547_residues
AIHPRAGQKAQQEDLHNIPVLVANYFLLEPNPANADQKVQFGTSGHRGTADKSTFNQHHIWAIAQAVVDVRKANGVTGPL
FLGKDTHALSEPAFTSAIEVFVANGVEVIIQENNGYTPTPGISHAILTHNVKFDEKADGIVITPSHNPPQDGGIKYNPVH
GGPAEGELTTAIENRANQLIANELKEVKRVSITEAMASDLVKQIDLVQPYIDDLKNVINIEAIQKANLKLGVDPLGGSGI
EYWRQIGQAFELDLTLVSEAIDPSFQFMSLDKDGVVRMDCSSPYAMAGLLSLKDDYDLAFGNDPDYDRHGIVTPSGLMNP
NHYLAVCIDYLYQNRPQWKSEVAVGKTLVSSAIIDKVVADLGRDLCEVPVGFKWFVDGLYNGTLGFGGEESAGASFLRFD
GTPWSTDKDGILLCLLAAEITAITGMNPQEYYNKLAAQHGESSYNRIQAVANKEQKAVLSKLSPEMVSATTLAGDEITAR
LTHAPGNGAAIGGLKVTTANGWFAARPSGTEEIYKIYCESFKGADHLALIEQEAQEIVSNVFKDAGL

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=409, Percent_Identity=24.9388753056235, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI290463102, Length=440, Percent_Identity=24.0909090909091, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI21361621, Length=440, Percent_Identity=23.8636363636364, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1786904, Length=546, Percent_Identity=69.2307692307692, Blast_Score=792, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=437, Percent_Identity=27.6887871853547, Blast_Score=93, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323752, Length=574, Percent_Identity=25.609756097561, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6322722, Length=490, Percent_Identity=27.1428571428571, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17864244, Length=430, Percent_Identity=26.2790697674419, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59246; Mature: 59115

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIHPRAGQKAQQEDLHNIPVLVANYFLLEPNPANADQKVQFGTSGHRGTADKSTFNQHH
CCCCCCCCCCHHHHHHCCCCEEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCHHH
IWAIAQAVVDVRKANGVTGPLFLGKDTHALSEPAFTSAIEVFVANGVEVIIQENNGYTPT
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCC
PGISHAILTHNVKFDEKADGIVITPSHNPPQDGGIKYNPVHGGPAEGELTTAIENRANQL
CCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
IANELKEVKRVSITEAMASDLVKQIDLVQPYIDDLKNVINIEAIQKANLKLGVDPLGGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCH
IEYWRQIGQAFELDLTLVSEAIDPSFQFMSLDKDGVVRMDCSSPYAMAGLLSLKDDYDLA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHCCCCCCCEE
FGNDPDYDRHGIVTPSGLMNPNHYLAVCIDYLYQNRPQWKSEVAVGKTLVSSAIIDKVVA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
DLGRDLCEVPVGFKWFVDGLYNGTLGFGGEESAGASFLRFDGTPWSTDKDGILLCLLAAE
HHCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEHHHH
ITAITGMNPQEYYNKLAAQHGESSYNRIQAVANKEQKAVLSKLSPEMVSATTLAGDEITA
HHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHCCHHHHHHHEECCCCEEE
RLTHAPGNGAAIGGLKVTTANGWFAARPSGTEEIYKIYCESFKGADHLALIEQEAQEIVS
EEEECCCCCEEECCEEEEECCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
NVFKDAGL
HHHHHCCC
>Mature Secondary Structure 
AIHPRAGQKAQQEDLHNIPVLVANYFLLEPNPANADQKVQFGTSGHRGTADKSTFNQHH
CCCCCCCCCHHHHHHCCCCEEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCHHH
IWAIAQAVVDVRKANGVTGPLFLGKDTHALSEPAFTSAIEVFVANGVEVIIQENNGYTPT
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCC
PGISHAILTHNVKFDEKADGIVITPSHNPPQDGGIKYNPVHGGPAEGELTTAIENRANQL
CCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHH
IANELKEVKRVSITEAMASDLVKQIDLVQPYIDDLKNVINIEAIQKANLKLGVDPLGGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCH
IEYWRQIGQAFELDLTLVSEAIDPSFQFMSLDKDGVVRMDCSSPYAMAGLLSLKDDYDLA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHCCCCCCCEE
FGNDPDYDRHGIVTPSGLMNPNHYLAVCIDYLYQNRPQWKSEVAVGKTLVSSAIIDKVVA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
DLGRDLCEVPVGFKWFVDGLYNGTLGFGGEESAGASFLRFDGTPWSTDKDGILLCLLAAE
HHCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEHHHH
ITAITGMNPQEYYNKLAAQHGESSYNRIQAVANKEQKAVLSKLSPEMVSATTLAGDEITA
HHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHCCHHHHHHHEECCCCEEE
RLTHAPGNGAAIGGLKVTTANGWFAARPSGTEEIYKIYCESFKGADHLALIEQEAQEIVS
EEEECCCCCEEECCEEEEECCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
NVFKDAGL
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]