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The map label for this gene is coaD

Identifier: 209693801

GI number: 209693801

Start: 227036

End: 227524

Strand: Direct

Name: coaD

Synonym: VSAL_I0186

Alternate gene names: 209693801

Gene position: 227036-227524 (Clockwise)

Preceding gene: 209693800

Following gene: 209693808

Centisome position: 6.83

GC content: 41.1

Gene sequence:

>489_bases
ATGACTAAATTAACGCTTTATCCTGGCACTTTTGATCCAATCACTAATGGGCATTTAGATTTAATTAAACGCTCTGCGGC
CATGTTTGAACACATTATTGTGGCGGTAGCGGCCAGCCCAAGTAAAAATACTTTATTTACGCTCGATGAGCGCGTTCAAT
TAGTGCAAGAAGTAACTCAGGATCTGCCAAACGTGTCCGTTGAGGGTTTCTCTGGACTAATGGTGGATTTCGCAAGACAG
AAACAAGCAAACCTATTGGTCCGAGGCTTAAGAACCACGATGGATTTTGAGTATGAATTTGGCTTAACTAGTATGTATCG
TAAGTTAATGCCAGAGTTAGAAAGTGTATTTCTTACGCCTTCTGAAGAGTATGCTTTTCTCTCTTCGACCATTGTTCGCG
AAGTGGCATTGCATGGGGGAAGTGTGGAAGCCTTTGTTCCTTCTGTGGTAAATCAAGCATTAATACATAAAGTAAAGTCA
CCAGTTTAA

Upstream 100 bases:

>100_bases
AAAGAGCACTTAATTGAAGGTGGGTGGGAAAAATTAACCGCCTTTATGATTGAGCATACTGCGGCTCTGTATTTCAAGGT
TTACCAACGAGCTTTACAAC

Downstream 100 bases:

>100_bases
TGCCCAAACAAAGGCCACTCAAATAAGTGGCCTATGATTACAATTAATGAACGCCTTTTACTTGGCTATTGATGTATAAG
GTTTGCAATGTGTGGTAATC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MTKLTLYPGTFDPITNGHLDLIKRSAAMFEHIIVAVAASPSKNTLFTLDERVQLVQEVTQDLPNVSVEGFSGLMVDFARQ
KQANLLVRGLRTTMDFEYEFGLTSMYRKLMPELESVFLTPSEEYAFLSSTIVREVALHGGSVEAFVPSVVNQALIHKVKS
PV

Sequences:

>Translated_162_residues
MTKLTLYPGTFDPITNGHLDLIKRSAAMFEHIIVAVAASPSKNTLFTLDERVQLVQEVTQDLPNVSVEGFSGLMVDFARQ
KQANLLVRGLRTTMDFEYEFGLTSMYRKLMPELESVFLTPSEEYAFLSSTIVREVALHGGSVEAFVPSVVNQALIHKVKS
PV
>Mature_161_residues
TKLTLYPGTFDPITNGHLDLIKRSAAMFEHIIVAVAASPSKNTLFTLDERVQLVQEVTQDLPNVSVEGFSGLMVDFARQK
QANLLVRGLRTTMDFEYEFGLTSMYRKLMPELESVFLTPSEEYAFLSSTIVREVALHGGSVEAFVPSVVNQALIHKVKSP
V

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=58.2278481012658, Blast_Score=200, Evalue=5e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_ALISL (B6EPN7)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002261729.1
- ProteinModelPortal:   B6EPN7
- GeneID:   6986366
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0186
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18022; Mature: 17891

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLTLYPGTFDPITNGHLDLIKRSAAMFEHIIVAVAASPSKNTLFTLDERVQLVQEVTQ
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHH
DLPNVSVEGFSGLMVDFARQKQANLLVRGLRTTMDFEYEFGLTSMYRKLMPELESVFLTP
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCC
SEEYAFLSSTIVREVALHGGSVEAFVPSVVNQALIHKVKSPV
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKLTLYPGTFDPITNGHLDLIKRSAAMFEHIIVAVAASPSKNTLFTLDERVQLVQEVTQ
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHH
DLPNVSVEGFSGLMVDFARQKQANLLVRGLRTTMDFEYEFGLTSMYRKLMPELESVFLTP
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCC
SEEYAFLSSTIVREVALHGGSVEAFVPSVVNQALIHKVKSPV
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA