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The map label for this gene is fepD [H]

Identifier: 209693761

GI number: 209693761

Start: 178517

End: 179617

Strand: Direct

Name: fepD [H]

Synonym: VSAL_I0139

Alternate gene names: 209693761

Gene position: 178517-179617 (Clockwise)

Preceding gene: 209693760

Following gene: 209693762

Centisome position: 5.37

GC content: 43.42

Gene sequence:

>1101_bases
ATGAATAACGCAGATAACCAATTAACTAGTACACCTGACTTGGCTATTCTCCCTTCTTTAATCAGCAGAAATAAAAAGGT
CACTACCACATTAATATTGCTAATTATATTAAGTTTTTCTGCAATTATTTCTGGGCTTCTTTTAGGAACAACAACCCTAT
CTCCCTTTTATCTACTGCGCTTATTTAGTGAAAATAATCTCAATCACGATACTCTTATTATACAAGCTCGACTCCCACGA
GTTCTGATTGGTTTATTGGCTGGAATGTCATTAGCAATGGCAGGCTGCGTCATGCAAGCCTTAACTCGAAACCCTTTAGC
TGATCCGGGTTTACTCGGTGTAAATGCGGGAGCGAATGCCTCAATAATAACACTCAGCTTATTATCATTCAGTGCCAACT
GGCCTCTTTTTTGGTTAGCGATTCCTGGTGCGTTACTCACGAGCGTGATGGTCTACTTATTGTCACGAGGCCACAATCAA
TCCCCAACAAGGCTTATCCTATCTGGTGCCGCCATTAGTGCCGTATTAGGTGCTTATGTGCAAGCAAGAGTCATCGTAAA
CCCATCGCTTTTTAGTGACCTAAAGTATTGGATGTCGGGGTCATTATCAGGACTCCAACTATCTGATATTAATACGATAT
GGCCTTACTTTATTATCGCTACTGTCATTCTTCTTCTATTAGCTCCTGCTTTAAATTTACTCTCTATCGATAGAAACATT
GCGATATCCTTGGGGGCGAATTTACGATGGCAGCCGCAACTAGGTTGGCTTGGCGCTACGATTTTGTGTGCGGCCTCAAC
CGCCACCGTCGGGTCACTGACTTTTGTTGGTTTAGCATCCGCCCACCTTTCTCGATTTATTGCCCCACAGGATTTTCGCT
GGCAATTGCCCATATCGGCACTCATTGGCGGTAACCTTGTTGTTATTGCTGATGTGATCGCCCGAACACTCATGCCTCCG
ACAGAGCTTATTACTGGCATCGTTGTCGCTATGCTCGGCGCTCCTTTTCTCTACCTCGCAGTGAGAAGAGATCAAATGAA
AAAGTCGTCATCAGTAACACCTTGTAAACGACGTCTGAAGAGAAACTCAAATGAAAACTAA

Upstream 100 bases:

>100_bases
CCGATCCCTCAATTGTAATGGCGACGTCCTATGGCAGTTTACTCAGTTTGGAATGGGTAATGCCCGCATTTATTCCAAAA
ATCAAAGAGGTTATGGGTAA

Downstream 100 bases:

>100_bases
TTTAGTCTCAACATGGCAGTTAGGGTCAATCGTAATACTGGCCCCAAGCAAAAGGACACTCAACGCCGTAATCATGGCGA
TGATATTAATCACCCTATCT

Product: iron-siderophore ABC transporter membrane permease component

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MNNADNQLTSTPDLAILPSLISRNKKVTTTLILLIILSFSAIISGLLLGTTTLSPFYLLRLFSENNLNHDTLIIQARLPR
VLIGLLAGMSLAMAGCVMQALTRNPLADPGLLGVNAGANASIITLSLLSFSANWPLFWLAIPGALLTSVMVYLLSRGHNQ
SPTRLILSGAAISAVLGAYVQARVIVNPSLFSDLKYWMSGSLSGLQLSDINTIWPYFIIATVILLLLAPALNLLSIDRNI
AISLGANLRWQPQLGWLGATILCAASTATVGSLTFVGLASAHLSRFIAPQDFRWQLPISALIGGNLVVIADVIARTLMPP
TELITGIVVAMLGAPFLYLAVRRDQMKKSSSVTPCKRRLKRNSNEN

Sequences:

>Translated_366_residues
MNNADNQLTSTPDLAILPSLISRNKKVTTTLILLIILSFSAIISGLLLGTTTLSPFYLLRLFSENNLNHDTLIIQARLPR
VLIGLLAGMSLAMAGCVMQALTRNPLADPGLLGVNAGANASIITLSLLSFSANWPLFWLAIPGALLTSVMVYLLSRGHNQ
SPTRLILSGAAISAVLGAYVQARVIVNPSLFSDLKYWMSGSLSGLQLSDINTIWPYFIIATVILLLLAPALNLLSIDRNI
AISLGANLRWQPQLGWLGATILCAASTATVGSLTFVGLASAHLSRFIAPQDFRWQLPISALIGGNLVVIADVIARTLMPP
TELITGIVVAMLGAPFLYLAVRRDQMKKSSSVTPCKRRLKRNSNEN
>Mature_366_residues
MNNADNQLTSTPDLAILPSLISRNKKVTTTLILLIILSFSAIISGLLLGTTTLSPFYLLRLFSENNLNHDTLIIQARLPR
VLIGLLAGMSLAMAGCVMQALTRNPLADPGLLGVNAGANASIITLSLLSFSANWPLFWLAIPGALLTSVMVYLLSRGHNQ
SPTRLILSGAAISAVLGAYVQARVIVNPSLFSDLKYWMSGSLSGLQLSDINTIWPYFIIATVILLLLAPALNLLSIDRNI
AISLGANLRWQPQLGWLGATILCAASTATVGSLTFVGLASAHLSRFIAPQDFRWQLPISALIGGNLVVIADVIARTLMPP
TELITGIVVAMLGAPFLYLAVRRDQMKKSSSVTPCKRRLKRNSNEN

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=303, Percent_Identity=40.5940594059406, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1790740, Length=281, Percent_Identity=33.0960854092527, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790741, Length=280, Percent_Identity=36.0714285714286, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=34.965034965035, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786347, Length=278, Percent_Identity=32.0143884892086, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786804, Length=333, Percent_Identity=30.6306306306306, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 39291; Mature: 39291

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNADNQLTSTPDLAILPSLISRNKKVTTTLILLIILSFSAIISGLLLGTTTLSPFYLLR
CCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LFSENNLNHDTLIIQARLPRVLIGLLAGMSLAMAGCVMQALTRNPLADPGLLGVNAGANA
HHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
SIITLSLLSFSANWPLFWLAIPGALLTSVMVYLLSRGHNQSPTRLILSGAAISAVLGAYV
CEEEEEEHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHH
QARVIVNPSLFSDLKYWMSGSLSGLQLSDINTIWPYFIIATVILLLLAPALNLLSIDRNI
HEEEEECHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
AISLGANLRWQPQLGWLGATILCAASTATVGSLTFVGLASAHLSRFIAPQDFRWQLPISA
EEEECCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHH
LIGGNLVVIADVIARTLMPPTELITGIVVAMLGAPFLYLAVRRDQMKKSSSVTPCKRRLK
HHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHH
RNSNEN
CCCCCC
>Mature Secondary Structure
MNNADNQLTSTPDLAILPSLISRNKKVTTTLILLIILSFSAIISGLLLGTTTLSPFYLLR
CCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LFSENNLNHDTLIIQARLPRVLIGLLAGMSLAMAGCVMQALTRNPLADPGLLGVNAGANA
HHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
SIITLSLLSFSANWPLFWLAIPGALLTSVMVYLLSRGHNQSPTRLILSGAAISAVLGAYV
CEEEEEEHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHH
QARVIVNPSLFSDLKYWMSGSLSGLQLSDINTIWPYFIIATVILLLLAPALNLLSIDRNI
HEEEEECHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
AISLGANLRWQPQLGWLGATILCAASTATVGSLTFVGLASAHLSRFIAPQDFRWQLPISA
EEEECCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHH
LIGGNLVVIADVIARTLMPPTELITGIVVAMLGAPFLYLAVRRDQMKKSSSVTPCKRRLK
HHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHH
RNSNEN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 1787794; 9278503 [H]