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The map label for this gene is hlyIII [H]

Identifier: 209693679

GI number: 209693679

Start: 52420

End: 53067

Strand: Direct

Name: hlyIII [H]

Synonym: VSAL_I0049

Alternate gene names: 209693679

Gene position: 52420-53067 (Clockwise)

Preceding gene: 209693678

Following gene: 209693685

Centisome position: 1.58

GC content: 36.11

Gene sequence:

>648_bases
ATGTCTACCACTACTCCTTATTCAAAAAAAGAAGAATTAGCCAATAGTTTAAGCCATGGTTTAGGGCTTGTTTTTGGTGT
TGTTGCGTTAATTTTATTATTGGTAAAAGCAAATGCAGTGGATGCAGACTGGTTAACCATCGCAAGTATGTCTGTTTATG
GGGCCAGTATCATTTTATTGTTTTTGGCTTCAACGCTTTATCATTCTATTGCTACACCTAAAGCGAAACGTTTATTAAAA
ACGCTCGATCACTGTGCCATCTTTTTACTTATTGCTGGCAGTTATACGCCATACTTATTAGTGAGTTTACGTACACCACT
CGCATATTGGTTAATGGCTGTGATCTGGGCTATCGCGTTGATAGGTATTATTGGAAAGATTGTTTTTGTCTATCGTTTTA
AAAAACTATCCCTTATTACCTACCTTATCATGGGTTGGTTATCGGTTATTGCGGTGTACCAATTAGTGATTCATATCGAT
ATTAATGGGGTGATTTTATTAGGCCTTGGAGGGGTGATTTATTCTCTTGGGGTTATTTTTTATGTGTCAAAGAAGATCCC
ATACAATCATGCTATTTGGCATCTGTTTGTTTTAGGCGGTTGTGTGACGCAATTCTTATCTATTTATTATTATGTTCAAC
CAGTATAA

Upstream 100 bases:

>100_bases
GCAATAAGATGTATTTTAAAGTGCCACATTTAAGCTTACAGTTGTACTCTTAAATGTGGCATACTGCTTTTATGTTGAGT
AATCACTCTATGAGAGTCCT

Downstream 100 bases:

>100_bases
ATAATTAGTATCGTTACTATAAAAAAATGGCGCTAGAGAGTCTCTGTTTATGAAGAGATCCTAGCGCCATTTTTGTATTG
AGTTGAATGCGTACTTACCC

Product: hemolysin III

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSTTTPYSKKEELANSLSHGLGLVFGVVALILLLVKANAVDADWLTIASMSVYGASIILLFLASTLYHSIATPKAKRLLK
TLDHCAIFLLIAGSYTPYLLVSLRTPLAYWLMAVIWAIALIGIIGKIVFVYRFKKLSLITYLIMGWLSVIAVYQLVIHID
INGVILLGLGGVIYSLGVIFYVSKKIPYNHAIWHLFVLGGCVTQFLSIYYYVQPV

Sequences:

>Translated_215_residues
MSTTTPYSKKEELANSLSHGLGLVFGVVALILLLVKANAVDADWLTIASMSVYGASIILLFLASTLYHSIATPKAKRLLK
TLDHCAIFLLIAGSYTPYLLVSLRTPLAYWLMAVIWAIALIGIIGKIVFVYRFKKLSLITYLIMGWLSVIAVYQLVIHID
INGVILLGLGGVIYSLGVIFYVSKKIPYNHAIWHLFVLGGCVTQFLSIYYYVQPV
>Mature_214_residues
STTTPYSKKEELANSLSHGLGLVFGVVALILLLVKANAVDADWLTIASMSVYGASIILLFLASTLYHSIATPKAKRLLKT
LDHCAIFLLIAGSYTPYLLVSLRTPLAYWLMAVIWAIALIGIIGKIVFVYRFKKLSLITYLIMGWLSVIAVYQLVIHIDI
NGVILLGLGGVIYSLGVIFYVSKKIPYNHAIWHLFVLGGCVTQFLSIYYYVQPV

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=226, Percent_Identity=30.5309734513274, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI52630445, Length=210, Percent_Identity=32.3809523809524, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI154759277, Length=250, Percent_Identity=27.6, Blast_Score=91, Evalue=6e-19,
Organism=Escherichia coli, GI1789266, Length=206, Percent_Identity=61.1650485436893, Blast_Score=249, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI71996356, Length=211, Percent_Identity=31.2796208530806, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640324, Length=220, Percent_Identity=31.3636363636364, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 23774; Mature: 23643

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTTPYSKKEELANSLSHGLGLVFGVVALILLLVKANAVDADWLTIASMSVYGASIILL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FLASTLYHSIATPKAKRLLKTLDHCAIFLLIAGSYTPYLLVSLRTPLAYWLMAVIWAIAL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGIIGKIVFVYRFKKLSLITYLIMGWLSVIAVYQLVIHIDINGVILLGLGGVIYSLGVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHH
YVSKKIPYNHAIWHLFVLGGCVTQFLSIYYYVQPV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STTTPYSKKEELANSLSHGLGLVFGVVALILLLVKANAVDADWLTIASMSVYGASIILL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FLASTLYHSIATPKAKRLLKTLDHCAIFLLIAGSYTPYLLVSLRTPLAYWLMAVIWAIAL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGIIGKIVFVYRFKKLSLITYLIMGWLSVIAVYQLVIHIDINGVILLGLGGVIYSLGVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHH
YVSKKIPYNHAIWHLFVLGGCVTQFLSIYYYVQPV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]