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The map label for this gene is rrp-2 [H]

Identifier: 203284656

GI number: 203284656

Start: 819798

End: 821153

Strand: Reverse

Name: rrp-2 [H]

Synonym: BDU_767

Alternate gene names: 203284656

Gene position: 821153-819798 (Counterclockwise)

Preceding gene: 203284657

Following gene: 203284654

Centisome position: 88.14

GC content: 29.13

Gene sequence:

>1356_bases
ATGAGTAAATTATTGGTAGCAGATGATGAAAAAAACATACGAGAAGGAATAGCAACTTATCTTGAAGAAGAAGGTTACTT
TGTATTTACTGCTAGTGATGGCGAAGAAGCTCTTGAAACAATTCAAAATGAAAAAATCGATGCTATAATATCTGATCTTC
GAATGCCTCAAATATCAGGAGAAGAATTATTAAAAATTGTAAAAGATAGAAATCCAAATATACCTTTTATCATTCTTACA
GCACACGGCACTGTAGATTCAGCTGTTGATGCTATGCGAGAGGGTGCTTATGACTTTTTAACAAAACCTGTTGACCTTGA
AAGACTATTATTAATCATCAAGCGAGCTTTAAAAAAAAGGAATGACAAAACACAACAAAATGTATTACAAAAAAACGTCA
TTATAAGAAAAAATTTAAGCTATTACGAAGAAATATTTGGAAAATCACTTATAATGCAAAAAATCTTAGAACTTGTAAAG
AAAATTGCAAAATCAAAAGCATCTGTTCTAATAACTGGAGAAAGCGGTGTTGGAAAAGAAGTAATAGCAGATGCAATATT
TGATTTATCAAATAGAAACGACAAACCTTTTATTAAAGTCAATTGTGCCGCACTATCTGAAAGCATACTTGAGAGTGAAC
TTTTTGGACATGAAAAAGGAGCATTCACAGGTGCAATTTCCCAAAAAAAAGGCAGATTTGAACTAGCGGATAAAGGAACC
ATATTTTTAGATGAAATAGTAGAAGTATCACCTGAAGTACAAGTAAAATTATTAAGAGTACTGCAAAATAAAACCTTTGA
ACGAGTAGGCGGAGAAACTACTATGCAAGTTGACATTAGGTTACTAACAGCAACAAATAAAAATATTGAAGAAGAAATTC
AAAAAGGAAAATTTAGAGAAGATTTATTTTATAGACTTAATATAATAAATATAAATATTCCACCATTAAGAGAAAGAAAA
GATGACATTCCAAATTTAACAAAAATACTAATTAAAGATGTTGCAAGTGAAAATAATAAAGAAGAAAAAAGTATTTCAAA
TGATGCACTAAAAGCTCTTTATGCATATGATTGGCCAGGGAATATCAGAGAATTAAAAAATGTACTTGAGAGTGCATTAA
TCCTATCTAAAGGGAAACAAATTGTTAAAGATGATCTACCCCCTAAAATCAAAAACAACACAAATCAATCATTTAATATA
ACACTACCAATAGGAATAAGCTTAAAAGAAGCAGAAAAAGAGATCATAAAACAAACACTTCTTCATTCCAAGAATAATAA
AAGTAAATGTGCTGAAATACTTAAAATTGGAAGAAAAACTTTACACAATAAAATCACAGAATATAAAATACATTAA

Upstream 100 bases:

>100_bases
GAAATTTTTGTAGAAAGTAAAGAAATGAAAGGAACATCTTTTACAATAACACTTCCAAAATTAAATAAAGGCAAAATTTT
AATTGAAGGATGTTTAGAAA

Downstream 100 bases:

>100_bases
CTATTAATAAATAATCAATATCAAACAATATAGCCATTATCTGATGGTGTATATTTTTTATACTAAAAAAATTCCAATAG
TAACAATAATATATCAAGTC

Product: response regulatory protein

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MSKLLVADDEKNIREGIATYLEEEGYFVFTASDGEEALETIQNEKIDAIISDLRMPQISGEELLKIVKDRNPNIPFIILT
AHGTVDSAVDAMREGAYDFLTKPVDLERLLLIIKRALKKRNDKTQQNVLQKNVIIRKNLSYYEEIFGKSLIMQKILELVK
KIAKSKASVLITGESGVGKEVIADAIFDLSNRNDKPFIKVNCAALSESILESELFGHEKGAFTGAISQKKGRFELADKGT
IFLDEIVEVSPEVQVKLLRVLQNKTFERVGGETTMQVDIRLLTATNKNIEEEIQKGKFREDLFYRLNIININIPPLRERK
DDIPNLTKILIKDVASENNKEEKSISNDALKALYAYDWPGNIRELKNVLESALILSKGKQIVKDDLPPKIKNNTNQSFNI
TLPIGISLKEAEKEIIKQTLLHSKNNKSKCAEILKIGRKTLHNKITEYKIH

Sequences:

>Translated_451_residues
MSKLLVADDEKNIREGIATYLEEEGYFVFTASDGEEALETIQNEKIDAIISDLRMPQISGEELLKIVKDRNPNIPFIILT
AHGTVDSAVDAMREGAYDFLTKPVDLERLLLIIKRALKKRNDKTQQNVLQKNVIIRKNLSYYEEIFGKSLIMQKILELVK
KIAKSKASVLITGESGVGKEVIADAIFDLSNRNDKPFIKVNCAALSESILESELFGHEKGAFTGAISQKKGRFELADKGT
IFLDEIVEVSPEVQVKLLRVLQNKTFERVGGETTMQVDIRLLTATNKNIEEEIQKGKFREDLFYRLNIININIPPLRERK
DDIPNLTKILIKDVASENNKEEKSISNDALKALYAYDWPGNIRELKNVLESALILSKGKQIVKDDLPPKIKNNTNQSFNI
TLPIGISLKEAEKEIIKQTLLHSKNNKSKCAEILKIGRKTLHNKITEYKIH
>Mature_450_residues
SKLLVADDEKNIREGIATYLEEEGYFVFTASDGEEALETIQNEKIDAIISDLRMPQISGEELLKIVKDRNPNIPFIILTA
HGTVDSAVDAMREGAYDFLTKPVDLERLLLIIKRALKKRNDKTQQNVLQKNVIIRKNLSYYEEIFGKSLIMQKILELVKK
IAKSKASVLITGESGVGKEVIADAIFDLSNRNDKPFIKVNCAALSESILESELFGHEKGAFTGAISQKKGRFELADKGTI
FLDEIVEVSPEVQVKLLRVLQNKTFERVGGETTMQVDIRLLTATNKNIEEEIQKGKFREDLFYRLNIININIPPLRERKD
DIPNLTKILIKDVASENNKEEKSISNDALKALYAYDWPGNIRELKNVLESALILSKGKQIVKDDLPPKIKNNTNQSFNIT
LPIGISLKEAEKEIIKQTLLHSKNNKSKCAEILKIGRKTLHNKITEYKIH

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=457, Percent_Identity=42.6695842450766, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1790437, Length=448, Percent_Identity=41.0714285714286, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI1790299, Length=467, Percent_Identity=37.9014989293362, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI1788905, Length=450, Percent_Identity=37.3333333333333, Blast_Score=320, Evalue=9e-89,
Organism=Escherichia coli, GI87082117, Length=267, Percent_Identity=47.565543071161, Blast_Score=268, Evalue=8e-73,
Organism=Escherichia coli, GI1789087, Length=286, Percent_Identity=43.7062937062937, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1789233, Length=323, Percent_Identity=41.7956656346749, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI87082152, Length=318, Percent_Identity=40.251572327044, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1786524, Length=354, Percent_Identity=37.2881355932203, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87081872, Length=326, Percent_Identity=38.0368098159509, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1787583, Length=341, Percent_Identity=36.3636363636364, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87081858, Length=300, Percent_Identity=29.6666666666667, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789828, Length=259, Percent_Identity=32.8185328185328, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789402, Length=133, Percent_Identity=27.0676691729323, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787487, Length=108, Percent_Identity=31.4814814814815, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=29.4117647058824, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790552, Length=207, Percent_Identity=20.7729468599034, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51041; Mature: 50910

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLLVADDEKNIREGIATYLEEEGYFVFTASDGEEALETIQNEKIDAIISDLRMPQISG
CCCCEECCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCCCH
EELLKIVKDRNPNIPFIILTAHGTVDSAVDAMREGAYDFLTKPVDLERLLLIIKRALKKR
HHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHC
NDKTQQNVLQKNVIIRKNLSYYEEIFGKSLIMQKILELVKKIAKSKASVLITGESGVGKE
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
VIADAIFDLSNRNDKPFIKVNCAALSESILESELFGHEKGAFTGAISQKKGRFELADKGT
HHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEECCHHCCCCCEEECCCCC
IFLDEIVEVSPEVQVKLLRVLQNKTFERVGGETTMQVDIRLLTATNKNIEEEIQKGKFRE
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCHHHHHHHCCCHH
DLFYRLNIININIPPLRERKDDIPNLTKILIKDVASENNKEEKSISNDALKALYAYDWPG
HHEEEEEEEEECCCCCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCC
NIRELKNVLESALILSKGKQIVKDDLPPKIKNNTNQSFNITLPIGISLKEAEKEIIKQTL
CHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHH
LHSKNNKSKCAEILKIGRKTLHNKITEYKIH
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKLLVADDEKNIREGIATYLEEEGYFVFTASDGEEALETIQNEKIDAIISDLRMPQISG
CCCEECCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCCCH
EELLKIVKDRNPNIPFIILTAHGTVDSAVDAMREGAYDFLTKPVDLERLLLIIKRALKKR
HHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHC
NDKTQQNVLQKNVIIRKNLSYYEEIFGKSLIMQKILELVKKIAKSKASVLITGESGVGKE
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
VIADAIFDLSNRNDKPFIKVNCAALSESILESELFGHEKGAFTGAISQKKGRFELADKGT
HHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEECCHHCCCCCEEECCCCC
IFLDEIVEVSPEVQVKLLRVLQNKTFERVGGETTMQVDIRLLTATNKNIEEEIQKGKFRE
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCHHHHHHHCCCHH
DLFYRLNIININIPPLRERKDDIPNLTKILIKDVASENNKEEKSISNDALKALYAYDWPG
HHEEEEEEEEECCCCCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCC
NIRELKNVLESALILSKGKQIVKDDLPPKIKNNTNQSFNITLPIGISLKEAEKEIIKQTL
CHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHH
LHSKNNKSKCAEILKIGRKTLHNKITEYKIH
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]