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The map label for this gene is ywlC [H]

Identifier: 203284630

GI number: 203284630

Start: 788860

End: 789864

Strand: Reverse

Name: ywlC [H]

Synonym: BDU_738

Alternate gene names: 203284630

Gene position: 789864-788860 (Counterclockwise)

Preceding gene: 203284632

Following gene: 203284627

Centisome position: 84.78

GC content: 29.25

Gene sequence:

>1005_bases
ATGAAAACAGAAGTAATAAAAGAAAGTGAAATAGAAAAAGCAGTGAAATTCATTAATTCAGGAGAATTAGTAGTATTTCC
CACAGAAACAGTATACGGCATTGGAGCTAATGCATATGATGAGAATGCTATACGAATGCTCTTTATAGTAAAAAAACGTC
CTATTACAAATCCCCTAATAGTACATGTTGAATCAATAGAAAAAATAAAAGAACTGGTAGAATATATACCAGATAGTGCT
ATGATTTTAATGAAAAAATTTACCCCAGGTCCCATAACATTCATATTAAAAAATGCGGGCAAGATATCTAAATTAATAAA
TGGAGGTCTTGAAAGTATAGCAGTCAGAATACCTTCAGACCCCATAGCTCTCAAATTAATCAAAATGAGCAAAGTTCCAA
TAGCAGCTCCATCAGCAAATTTATCAAAACGTCCCAGTGCCACTAATTTCGAAATGGCAATAAAAGAACTTAACGGTCTT
GTTAAAGGAATCATTCAGAAAAATGAAGTATCACAAATTGGAATAGAATCAACTGTTATAAGTTTTGACGCTAAAAGCAA
CGTATCAATATTAAGACCAGGATCAATAACAAAAGAAATGATAGAGAGAGAACTTAATGGAAAATTTAATGTAGAATATT
CATTAGGGAAAAAAATACTCCAACAATCACCAGGAAATTTATTGGAACATTATAGACCACGCATACCCGTTTATTTATTT
AGACAAAAAGATAATATAAGAAAGTATATATCACGACAAGATACAAAAATACTCATTATGAAAAATACTATTAAATCATA
TTGGTTTAATAAGCTTTGGAATACAAATCACATCTGTGTATTTAACACATTAGAAGAATATGCAAAAAATATTTATAAAG
TTTTTGTAGAATCTGAGAGAACACATAAACAAATACTTGCTGAATTTGTAGATAATAATCAACTTGGATATTCAATCAAT
AACAGACTCAAAAAAGCAAGTCTAGACAAATTTATTTCTGAATAA

Upstream 100 bases:

>100_bases
TAAGACTTATAACACAAAATTAATTAGTTGACCTAAATTGTTTATTTTCAATTTTTTTGATTTAATAAATATGCTAAGAT
AACCTTAATAGGTAGCATTA

Downstream 100 bases:

>100_bases
ATTTAAATTATTTTTCTAACAATTCCAAATACTTAAGAGCAATAGGATCATTTGGATCATATTCAAGAATGATTTGAAAA
TATTCTCTAGCCTCTTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKTEVIKESEIEKAVKFINSGELVVFPTETVYGIGANAYDENAIRMLFIVKKRPITNPLIVHVESIEKIKELVEYIPDSA
MILMKKFTPGPITFILKNAGKISKLINGGLESIAVRIPSDPIALKLIKMSKVPIAAPSANLSKRPSATNFEMAIKELNGL
VKGIIQKNEVSQIGIESTVISFDAKSNVSILRPGSITKEMIERELNGKFNVEYSLGKKILQQSPGNLLEHYRPRIPVYLF
RQKDNIRKYISRQDTKILIMKNTIKSYWFNKLWNTNHICVFNTLEEYAKNIYKVFVESERTHKQILAEFVDNNQLGYSIN
NRLKKASLDKFISE

Sequences:

>Translated_334_residues
MKTEVIKESEIEKAVKFINSGELVVFPTETVYGIGANAYDENAIRMLFIVKKRPITNPLIVHVESIEKIKELVEYIPDSA
MILMKKFTPGPITFILKNAGKISKLINGGLESIAVRIPSDPIALKLIKMSKVPIAAPSANLSKRPSATNFEMAIKELNGL
VKGIIQKNEVSQIGIESTVISFDAKSNVSILRPGSITKEMIERELNGKFNVEYSLGKKILQQSPGNLLEHYRPRIPVYLF
RQKDNIRKYISRQDTKILIMKNTIKSYWFNKLWNTNHICVFNTLEEYAKNIYKVFVESERTHKQILAEFVDNNQLGYSIN
NRLKKASLDKFISE
>Mature_334_residues
MKTEVIKESEIEKAVKFINSGELVVFPTETVYGIGANAYDENAIRMLFIVKKRPITNPLIVHVESIEKIKELVEYIPDSA
MILMKKFTPGPITFILKNAGKISKLINGGLESIAVRIPSDPIALKLIKMSKVPIAAPSANLSKRPSATNFEMAIKELNGL
VKGIIQKNEVSQIGIESTVISFDAKSNVSILRPGSITKEMIERELNGKFNVEYSLGKKILQQSPGNLLEHYRPRIPVYLF
RQKDNIRKYISRQDTKILIMKNTIKSYWFNKLWNTNHICVFNTLEEYAKNIYKVFVESERTHKQILAEFVDNNQLGYSIN
NRLKKASLDKFISE

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=190, Percent_Identity=26.8421052631579, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI2367210, Length=177, Percent_Identity=26.5536723163842, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87081864, Length=132, Percent_Identity=28.030303030303, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17537239, Length=201, Percent_Identity=26.865671641791, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=384, Percent_Identity=28.90625, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI78707274, Length=200, Percent_Identity=26, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 38008; Mature: 38008

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTEVIKESEIEKAVKFINSGELVVFPTETVYGIGANAYDENAIRMLFIVKKRPITNPLI
CCCCHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCCCEEEEEEEECCCCCCCEE
VHVESIEKIKELVEYIPDSAMILMKKFTPGPITFILKNAGKISKLINGGLESIAVRIPSD
EEHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHCCHHHEEEECCCC
PIALKLIKMSKVPIAAPSANLSKRPSATNFEMAIKELNGLVKGIIQKNEVSQIGIESTVI
CEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEE
SFDAKSNVSILRPGSITKEMIERELNGKFNVEYSLGKKILQQSPGNLLEHYRPRIPVYLF
EECCCCCCEEECCCHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCHHHHHHCCCCCEEEE
RQKDNIRKYISRQDTKILIMKNTIKSYWFNKLWNTNHICVFNTLEEYAKNIYKVFVESER
ECCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCH
THKQILAEFVDNNQLGYSINNRLKKASLDKFISE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTEVIKESEIEKAVKFINSGELVVFPTETVYGIGANAYDENAIRMLFIVKKRPITNPLI
CCCCHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCCCEEEEEEEECCCCCCCEE
VHVESIEKIKELVEYIPDSAMILMKKFTPGPITFILKNAGKISKLINGGLESIAVRIPSD
EEHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHCCHHHEEEECCCC
PIALKLIKMSKVPIAAPSANLSKRPSATNFEMAIKELNGLVKGIIQKNEVSQIGIESTVI
CEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEE
SFDAKSNVSILRPGSITKEMIERELNGKFNVEYSLGKKILQQSPGNLLEHYRPRIPVYLF
EECCCCCCEEECCCHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCHHHHHHCCCCCEEEE
RQKDNIRKYISRQDTKILIMKNTIKSYWFNKLWNTNHICVFNTLEEYAKNIYKVFVESER
ECCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCH
THKQILAEFVDNNQLGYSINNRLKKASLDKFISE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]