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The map label for this gene is mraY

Identifier: 203284224

GI number: 203284224

Start: 325835

End: 326890

Strand: Reverse

Name: mraY

Synonym: BDU_306

Alternate gene names: 203284224

Gene position: 326890-325835 (Counterclockwise)

Preceding gene: 203284225

Following gene: 203284223

Centisome position: 35.09

GC content: 28.88

Gene sequence:

>1056_bases
ATGTTTTGTTTTTTAGGACTTAGATTATTGAAATATATTACTTTTAGAACCGCTTATGCTACTATTTTTGCATTTTTGCT
TGCTTTAATTTTTGGTCCATTTATTATCTCAAGGCTTAAGAAATTAAAATTGGATCAAATTTTAAGAAAGGATGGACCAA
AACGCCATTTAAGTGAAAAAATGGGAATTCCTACTATGGGTGGTGTTCTTATTTTTTTTTGTGTTTTAGTTTCTTTATTT
TTTTGGATTCATTTTTTTAATATTTATTTTTTAATTGTACTGTTTGTTATGGTTAGTTTTGCGTGTTTGGGATTTACAGA
TGATTTGCTTAAAATAAAAAGGAAAAATTCGGATGGACTTAATCCTAAATTTAAGATTTATGGGCAAATATTATTTTCTT
TTATTTCAGTTGTTATGCTTTACTATTTTGGTGGAGAACATGTTAGTATACTTTATTTTCCATTTTTCAAATCTCTCAAA
TTAGATTTGGGAATTTTATATATTCCATTTGGGATGTTTGTTCTGATATCTGCATCTAATTCTTTTAATTTAACAGATGG
GCTTGATGGACTTGCTATTGGACTTAGTATTGTTGTAATAGGTGCTTTAATAATAATTGCATATCTTACAAGTAGAGTTG
ATTTTGCATTGTATTTAAATATTCCAAATGTTAAAGGTTGTGAAGAACTTGTAATATTTCTTGGGGCTTTGCTTGGTGGT
AGTTTTGGATTTTTGTGGTTTAATGCATATCCTGCTAAAATAATGATGGGTGATACTGGTAGTCTTTCAATAGGTGCAGT
ACTTGGAATGGTAGCTTTGATTTTAAAGAGTGAAATTCTTTTTGCAATCCTTGCAGGAGTTTTTGTTGTAGAAACTTTAT
CTGTAATTATTCAAGTTGTGGTTTATAAGAAAACCAAAAAAAGGGTATTTAAAATGGCGCCACTTCATCATCATTTTGAG
GAGCTTGGGTGGTCTGAAATGCAGGTTGTTATTAGATTTTGGATCATAGGTTTAATATTTGCTATACTTGCTTTAAGTAC
TATTAAGATTAGATAA

Upstream 100 bases:

>100_bases
CTTTAGAATCAGGGTGTTTTATTGCGATTAAAGGGTCAAGGACAAATAGACTTGAGAGAGTGCTTGACTATCTTTGAATT
AATGGTGGAAGAGAGGATTT

Downstream 100 bases:

>100_bases
GAAATTTAGATTGGGAGTTATGTTTGTAGAGAAAACCTCTCTTAGAAAATGTTATTTTCTTGTTTTATTTTCACTTATTT
CTTATGGTCTTATTGTATTT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MFCFLGLRLLKYITFRTAYATIFAFLLALIFGPFIISRLKKLKLDQILRKDGPKRHLSEKMGIPTMGGVLIFFCVLVSLF
FWIHFFNIYFLIVLFVMVSFACLGFTDDLLKIKRKNSDGLNPKFKIYGQILFSFISVVMLYYFGGEHVSILYFPFFKSLK
LDLGILYIPFGMFVLISASNSFNLTDGLDGLAIGLSIVVIGALIIIAYLTSRVDFALYLNIPNVKGCEELVIFLGALLGG
SFGFLWFNAYPAKIMMGDTGSLSIGAVLGMVALILKSEILFAILAGVFVVETLSVIIQVVVYKKTKKRVFKMAPLHHHFE
ELGWSEMQVVIRFWIIGLIFAILALSTIKIR

Sequences:

>Translated_351_residues
MFCFLGLRLLKYITFRTAYATIFAFLLALIFGPFIISRLKKLKLDQILRKDGPKRHLSEKMGIPTMGGVLIFFCVLVSLF
FWIHFFNIYFLIVLFVMVSFACLGFTDDLLKIKRKNSDGLNPKFKIYGQILFSFISVVMLYYFGGEHVSILYFPFFKSLK
LDLGILYIPFGMFVLISASNSFNLTDGLDGLAIGLSIVVIGALIIIAYLTSRVDFALYLNIPNVKGCEELVIFLGALLGG
SFGFLWFNAYPAKIMMGDTGSLSIGAVLGMVALILKSEILFAILAGVFVVETLSVIIQVVVYKKTKKRVFKMAPLHHHFE
ELGWSEMQVVIRFWIIGLIFAILALSTIKIR
>Mature_351_residues
MFCFLGLRLLKYITFRTAYATIFAFLLALIFGPFIISRLKKLKLDQILRKDGPKRHLSEKMGIPTMGGVLIFFCVLVSLF
FWIHFFNIYFLIVLFVMVSFACLGFTDDLLKIKRKNSDGLNPKFKIYGQILFSFISVVMLYYFGGEHVSILYFPFFKSLK
LDLGILYIPFGMFVLISASNSFNLTDGLDGLAIGLSIVVIGALIIIAYLTSRVDFALYLNIPNVKGCEELVIFLGALLGG
SFGFLWFNAYPAKIMMGDTGSLSIGAVLGMVALILKSEILFAILAGVFVVETLSVIIQVVVYKKTKKRVFKMAPLHHHFE
ELGWSEMQVVIRFWIIGLIFAILALSTIKIR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=349, Percent_Identity=42.1203438395415, Blast_Score=290, Evalue=9e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_BORDL (B5RLC9)

Other databases:

- EMBL:   CP000976
- RefSeq:   YP_002221964.1
- EnsemblBacteria:   EBBORT00000000976
- GeneID:   6918390
- GenomeReviews:   CP000976_GR
- KEGG:   bdu:BDU_306
- GeneTree:   EBGT00050000007216
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 39559; Mature: 39559

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x23abdcd0)-; HASH(0x22d42ccc)-; HASH(0x23a68284)-; HASH(0x239faad8)-; HASH(0x22fa3384)-; HASH(0x2369fb14)-; HASH(0x218aa34c)-; HASH(0x2353cc6c)-; HASH(0x23224db8)-; HASH(0x22a33e8c)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCFLGLRLLKYITFRTAYATIFAFLLALIFGPFIISRLKKLKLDQILRKDGPKRHLSEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MGIPTMGGVLIFFCVLVSLFFWIHFFNIYFLIVLFVMVSFACLGFTDDLLKIKRKNSDGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
NPKFKIYGQILFSFISVVMLYYFGGEHVSILYFPFFKSLKLDLGILYIPFGMFVLISASN
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEECCC
SFNLTDGLDGLAIGLSIVVIGALIIIAYLTSRVDFALYLNIPNVKGCEELVIFLGALLGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCC
SFGFLWFNAYPAKIMMGDTGSLSIGAVLGMVALILKSEILFAILAGVFVVETLSVIIQVV
CHHHHEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYKKTKKRVFKMAPLHHHFEELGWSEMQVVIRFWIIGLIFAILALSTIKIR
HHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MFCFLGLRLLKYITFRTAYATIFAFLLALIFGPFIISRLKKLKLDQILRKDGPKRHLSEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MGIPTMGGVLIFFCVLVSLFFWIHFFNIYFLIVLFVMVSFACLGFTDDLLKIKRKNSDGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
NPKFKIYGQILFSFISVVMLYYFGGEHVSILYFPFFKSLKLDLGILYIPFGMFVLISASN
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEECCC
SFNLTDGLDGLAIGLSIVVIGALIIIAYLTSRVDFALYLNIPNVKGCEELVIFLGALLGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCC
SFGFLWFNAYPAKIMMGDTGSLSIGAVLGMVALILKSEILFAILAGVFVVETLSVIIQVV
CHHHHEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYKKTKKRVFKMAPLHHHFEELGWSEMQVVIRFWIIGLIFAILALSTIKIR
HHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA