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The map label for this gene is gufA [H]

Identifier: 203284139

GI number: 203284139

Start: 234751

End: 235572

Strand: Reverse

Name: gufA [H]

Synonym: BDU_220

Alternate gene names: 203284139

Gene position: 235572-234751 (Counterclockwise)

Preceding gene: 203284140

Following gene: 203284134

Centisome position: 25.28

GC content: 34.79

Gene sequence:

>822_bases
ATGTTTAAGCATTTGTGTGATTATTTATTAACTCTTCATCCTATTTTTTTAGGGTTTTTGGGTTCTGTTTTTACTTGGTT
TACCACTGCTTTTGGAGCAGCTGCTGTTTTTTGTTTTAGGCGAGTCAATAATAAAATAATGGATGCTATGCTTGGATTTT
CGGCAGGAATTATGATTGCTGCTAGTTTTTTTTCGCTTATTAAACCAGCAATAGAAATGGCAGAAGAGCTTGGTTATGTT
ACGTGGATACCTGCAGTTTGTGGTTTTCTTTGTGGTGCATTTTTTATATATATTGTAGATGTATTTGTGCCAGACCTTGA
AAAGTTAACATTTATTGATGAAGATTTAACCAGACATGGAAAGAAGGATTTTTTGCTTTTTACAGCTGTAACTTTGCATA
ATTTTCCCGAAGGACTTGCTGTTGGTGTTGCTTTTGGTGCTCTAGCATCTTCTCCTGATCTGCATACTTTAGTTGGAGCT
ATGATTCTTACATTGGGAATTGGTATTCAAAATATGCCAGAAGGTGCGGCTATTTCTTTGCCTTTAAGAAGAGGCCATGT
TCCTTTATGGAAGTGTTTTAATTATGGACAAATGTCAGGATTGGTGGAAATTATTGGAGGCTTTTTGGGTTCTTATGCTG
TTTATACTTTTACTAGAATTTTACCCTTTGCTTTATCCTTTTCTGCAGGTGCAATGATTTATGTCTCAATTGAACAATTA
ATACCTGAGGCTAAAAGGAAAGATATTGATAATAAGATCCCGACCATATTTGGAGTTATTGGGTTTTCTTTAATGATGTT
CCTTGATGTTTCTTTGGGTTAA

Upstream 100 bases:

>100_bases
TGGCACTTTTAAGATACAAAAAGAACAAGCTTCTTCATCAGGAATAAGGAGAATAAGGGCAATTTTGATATGATAATAGA
AAAATTATGGAGGATACTTT

Downstream 100 bases:

>100_bases
TTTAACCAAATTTACCGGTGATATATTCTTCTGTTTTAATATTCTTAGGATTGAAGAATAATTCATCTGTTTTGCTTTCT
TCTTCAATGTATCCATTTAA

Product: GufA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MFKHLCDYLLTLHPIFLGFLGSVFTWFTTAFGAAAVFCFRRVNNKIMDAMLGFSAGIMIAASFFSLIKPAIEMAEELGYV
TWIPAVCGFLCGAFFIYIVDVFVPDLEKLTFIDEDLTRHGKKDFLLFTAVTLHNFPEGLAVGVAFGALASSPDLHTLVGA
MILTLGIGIQNMPEGAAISLPLRRGHVPLWKCFNYGQMSGLVEIIGGFLGSYAVYTFTRILPFALSFSAGAMIYVSIEQL
IPEAKRKDIDNKIPTIFGVIGFSLMMFLDVSLG

Sequences:

>Translated_273_residues
MFKHLCDYLLTLHPIFLGFLGSVFTWFTTAFGAAAVFCFRRVNNKIMDAMLGFSAGIMIAASFFSLIKPAIEMAEELGYV
TWIPAVCGFLCGAFFIYIVDVFVPDLEKLTFIDEDLTRHGKKDFLLFTAVTLHNFPEGLAVGVAFGALASSPDLHTLVGA
MILTLGIGIQNMPEGAAISLPLRRGHVPLWKCFNYGQMSGLVEIIGGFLGSYAVYTFTRILPFALSFSAGAMIYVSIEQL
IPEAKRKDIDNKIPTIFGVIGFSLMMFLDVSLG
>Mature_273_residues
MFKHLCDYLLTLHPIFLGFLGSVFTWFTTAFGAAAVFCFRRVNNKIMDAMLGFSAGIMIAASFFSLIKPAIEMAEELGYV
TWIPAVCGFLCGAFFIYIVDVFVPDLEKLTFIDEDLTRHGKKDFLLFTAVTLHNFPEGLAVGVAFGALASSPDLHTLVGA
MILTLGIGIQNMPEGAAISLPLRRGHVPLWKCFNYGQMSGLVEIIGGFLGSYAVYTFTRILPFALSFSAGAMIYVSIEQL
IPEAKRKDIDNKIPTIFGVIGFSLMMFLDVSLG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=331, Percent_Identity=33.2326283987915, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI229577422, Length=336, Percent_Identity=32.4404761904762, Blast_Score=150, Evalue=1e-36,
Organism=Escherichia coli, GI1789419, Length=248, Percent_Identity=26.6129032258064, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507805, Length=321, Percent_Identity=38.3177570093458, Blast_Score=190, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24652846, Length=177, Percent_Identity=44.6327683615819, Blast_Score=131, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 29918; Mature: 29918

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]