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The map label for this gene is atpB [H]

Identifier: 203284018

GI number: 203284018

Start: 100792

End: 102099

Strand: Reverse

Name: atpB [H]

Synonym: BDU_96

Alternate gene names: 203284018

Gene position: 102099-100792 (Counterclockwise)

Preceding gene: 203284019

Following gene: 203284017

Centisome position: 10.96

GC content: 35.47

Gene sequence:

>1308_bases
GTGCAAATGAAGAGAGTATATAGTAAGATAGAATCTATTATTGGGAATGTAATAACTGTTATAGCAAAAAGTGTTAAATA
TGGAGAACTTGCCATTGTAAAATCCAAAAATGGAAGTTCCTTAGCGGAAGTGATTAAGCTAGAGAGGGATAAGGTTTCTC
TGCAAGTTTATAATGGAACAATAGGCATTTCAACTTCAGATGAAGTTAAGTTTTTGGGCCATCCAATGCAAGTAACATTT
TCTGAAAATTTACTTGGTAGAATTTTTGATGGTGCTGGTAATCCTAAAGACGGAGGGCCACGTCTTGAGGATAATTTAAT
TGAAATTGGTGGTCCATCGGTTAATCCTGCAAAGCGTATTGTGCCAAGAAATATGATAAGGACTGGAATTCCAATGATAG
ATGTTTTTAATACTCTTGTTGAATCTCAGAAATTACCAATATTTTCTGTGTCTGGGGAACCTTATAATGAGCTTCTTGTA
AGGATAGCTCTTCAAGCTGAGGTTGATCTCATTATTCTTGGAGGAATGGGACTTAAAAATGATGATTATTTAACGTTTAA
GGATTCACTTGAGAGTGGTGGAGCTTTAAGTAGGACAATCTTTTTTGTAAATACAGCCAATGATCCTGTTGTTGAGTCTT
TAATTGTTCCTGATATTTCTCTTGCTGTTGCTGAAAAATTTGCTTTGCAGGGAAAAAAAGTTTTGGTACTTTTAACCGAT
ATGACCAATTTTGCGGATGCTATGAAAGAAATAGCTATTACTATGGAGCAAGTGCCATCTAATAGAGGTTATCCTGGTGA
TTTATATTCTCAGCTTGCATCTAGATATGAGAAGGCTATTGATTTTGAAGGTGCAGGATCAATTACTGTACTTGCAGTTA
CTACAATGCCTGGAGATGATGTTACTCATCCAGTACCTGATAATACGGGTTATATTACTGAAGGACAATACTATTTAAGG
AGAGGCAGAATTGAGCCTTTTGGCTCTCTTTCAAGACTTAAGCAAATGGTTAATGGAAAGACAAGAGATGACCATAGGAC
GATTATGGATTCAATGATTAAGCTTTATGCATCTTCAAGAGAATCTATAGAGAAAAAAGCTATGGGATTTAATATGACAG
AGTGGGATGAAAAGCTTCTTAAGTATAGCAATATGTTTGAGAGTAAACTTATGGATTTGTCTCTTAATATTCCGTTAGAA
GAGGCTTTGGATTTGGGTTGGACTATTCTCTCTAGTTGTTTTGAACCTAATGAGACTGGCATTAAAACAGAACTGCTGGA
AAAGTATTGGCCTAAAAATAGGGATTAG

Upstream 100 bases:

>100_bases
TTTAGATATGAATCTTGCTCCCTTTAAGCAAGAAAAGTTTAATAAATTAGAAATTAATTTAAAAAATTTATTACGTTCTA
AAAAATTGGATTTTTGAGGT

Downstream 100 bases:

>100_bases
AGATGCCTAAAGTTAAGTTGACAAAAAATGAACTTAAAAAACAAAAAGATGATCTTAAAATGTTTAGTAGGTATTTACCT
ACGTTGCAACTTAAAAAACA

Product: V-type ATP synthase subunit B

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit B [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MQMKRVYSKIESIIGNVITVIAKSVKYGELAIVKSKNGSSLAEVIKLERDKVSLQVYNGTIGISTSDEVKFLGHPMQVTF
SENLLGRIFDGAGNPKDGGPRLEDNLIEIGGPSVNPAKRIVPRNMIRTGIPMIDVFNTLVESQKLPIFSVSGEPYNELLV
RIALQAEVDLIILGGMGLKNDDYLTFKDSLESGGALSRTIFFVNTANDPVVESLIVPDISLAVAEKFALQGKKVLVLLTD
MTNFADAMKEIAITMEQVPSNRGYPGDLYSQLASRYEKAIDFEGAGSITVLAVTTMPGDDVTHPVPDNTGYITEGQYYLR
RGRIEPFGSLSRLKQMVNGKTRDDHRTIMDSMIKLYASSRESIEKKAMGFNMTEWDEKLLKYSNMFESKLMDLSLNIPLE
EALDLGWTILSSCFEPNETGIKTELLEKYWPKNRD

Sequences:

>Translated_435_residues
MQMKRVYSKIESIIGNVITVIAKSVKYGELAIVKSKNGSSLAEVIKLERDKVSLQVYNGTIGISTSDEVKFLGHPMQVTF
SENLLGRIFDGAGNPKDGGPRLEDNLIEIGGPSVNPAKRIVPRNMIRTGIPMIDVFNTLVESQKLPIFSVSGEPYNELLV
RIALQAEVDLIILGGMGLKNDDYLTFKDSLESGGALSRTIFFVNTANDPVVESLIVPDISLAVAEKFALQGKKVLVLLTD
MTNFADAMKEIAITMEQVPSNRGYPGDLYSQLASRYEKAIDFEGAGSITVLAVTTMPGDDVTHPVPDNTGYITEGQYYLR
RGRIEPFGSLSRLKQMVNGKTRDDHRTIMDSMIKLYASSRESIEKKAMGFNMTEWDEKLLKYSNMFESKLMDLSLNIPLE
EALDLGWTILSSCFEPNETGIKTELLEKYWPKNRD
>Mature_435_residues
MQMKRVYSKIESIIGNVITVIAKSVKYGELAIVKSKNGSSLAEVIKLERDKVSLQVYNGTIGISTSDEVKFLGHPMQVTF
SENLLGRIFDGAGNPKDGGPRLEDNLIEIGGPSVNPAKRIVPRNMIRTGIPMIDVFNTLVESQKLPIFSVSGEPYNELLV
RIALQAEVDLIILGGMGLKNDDYLTFKDSLESGGALSRTIFFVNTANDPVVESLIVPDISLAVAEKFALQGKKVLVLLTD
MTNFADAMKEIAITMEQVPSNRGYPGDLYSQLASRYEKAIDFEGAGSITVLAVTTMPGDDVTHPVPDNTGYITEGQYYLR
RGRIEPFGSLSRLKQMVNGKTRDDHRTIMDSMIKLYASSRESIEKKAMGFNMTEWDEKLLKYSNMFESKLMDLSLNIPLE
EALDLGWTILSSCFEPNETGIKTELLEKYWPKNRD

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit [H]

COG id: COG1156

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913426, Length=438, Percent_Identity=35.8447488584475, Blast_Score=258, Evalue=6e-69,
Organism=Homo sapiens, GI19913428, Length=466, Percent_Identity=34.549356223176, Blast_Score=258, Evalue=9e-69,
Organism=Homo sapiens, GI50345984, Length=291, Percent_Identity=27.4914089347079, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4757810, Length=291, Percent_Identity=27.4914089347079, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI32189394, Length=298, Percent_Identity=25.1677852348993, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788251, Length=332, Percent_Identity=24.0963855421687, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790172, Length=321, Percent_Identity=26.1682242990654, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790170, Length=343, Percent_Identity=24.7813411078717, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17570191, Length=441, Percent_Identity=37.6417233560091, Blast_Score=271, Evalue=7e-73,
Organism=Caenorhabditis elegans, GI17510931, Length=449, Percent_Identity=36.7483296213808, Blast_Score=260, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71988080, Length=302, Percent_Identity=26.8211920529801, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=302, Percent_Identity=26.8211920529801, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71988074, Length=254, Percent_Identity=25.9842519685039, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25144756, Length=298, Percent_Identity=25.8389261744966, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319603, Length=427, Percent_Identity=37.2365339578454, Blast_Score=263, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6319370, Length=296, Percent_Identity=25.3378378378378, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322581, Length=394, Percent_Identity=24.6192893401015, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281361666, Length=467, Percent_Identity=34.6895074946467, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24646341, Length=467, Percent_Identity=34.6895074946467, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI17136796, Length=467, Percent_Identity=34.6895074946467, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24658560, Length=291, Percent_Identity=26.4604810996564, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24638766, Length=295, Percent_Identity=24.406779661017, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR004100
- InterPro:   IPR022879 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N [H]

EC number: 3.6.3.14

Molecular weight: Translated: 48289; Mature: 48289

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMKRVYSKIESIIGNVITVIAKSVKYGELAIVKSKNGSSLAEVIKLERDKVSLQVYNGT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEEECE
IGISTSDEVKFLGHPMQVTFSENLLGRIFDGAGNPKDGGPRLEDNLIEIGGPSVNPAKRI
EECCCCCCHHCCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCHHHHH
VPRNMIRTGIPMIDVFNTLVESQKLPIFSVSGEPYNELLVRIALQAEVDLIILGGMGLKN
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCC
DDYLTFKDSLESGGALSRTIFFVNTANDPVVESLIVPDISLAVAEKFALQGKKVLVLLTD
CCEEEECCCCCCCCCEEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEC
MTNFADAMKEIAITMEQVPSNRGYPGDLYSQLASRYEKAIDFEGAGSITVLAVTTMPGDD
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCC
VTHPVPDNTGYITEGQYYLRRGRIEPFGSLSRLKQMVNGKTRDDHRTIMDSMIKLYASSR
CCCCCCCCCCEEECCHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ESIEKKAMGFNMTEWDEKLLKYSNMFESKLMDLSLNIPLEEALDLGWTILSSCFEPNETG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCCCC
IKTELLEKYWPKNRD
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MQMKRVYSKIESIIGNVITVIAKSVKYGELAIVKSKNGSSLAEVIKLERDKVSLQVYNGT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEEECE
IGISTSDEVKFLGHPMQVTFSENLLGRIFDGAGNPKDGGPRLEDNLIEIGGPSVNPAKRI
EECCCCCCHHCCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCHHHHH
VPRNMIRTGIPMIDVFNTLVESQKLPIFSVSGEPYNELLVRIALQAEVDLIILGGMGLKN
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCC
DDYLTFKDSLESGGALSRTIFFVNTANDPVVESLIVPDISLAVAEKFALQGKKVLVLLTD
CCEEEECCCCCCCCCEEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEC
MTNFADAMKEIAITMEQVPSNRGYPGDLYSQLASRYEKAIDFEGAGSITVLAVTTMPGDD
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCC
VTHPVPDNTGYITEGQYYLRRGRIEPFGSLSRLKQMVNGKTRDDHRTIMDSMIKLYASSR
CCCCCCCCCCEEECCHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ESIEKKAMGFNMTEWDEKLLKYSNMFESKLMDLSLNIPLEEALDLGWTILSSCFEPNETG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCCCC
IKTELLEKYWPKNRD
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Borate; Diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines various reactions catalyzed by ATPase, analogs; Oligomycin; Quercetin; Trialkyl tinderivatives; Venturicidin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA