Click here to switch to the map view.

The map label for this gene is atpA [H]

Identifier: 203284019

GI number: 203284019

Start: 102103

End: 103833

Strand: Reverse

Name: atpA [H]

Synonym: BDU_97

Alternate gene names: 203284019

Gene position: 103833-102103 (Counterclockwise)

Preceding gene: 203284020

Following gene: 203284018

Centisome position: 11.14

GC content: 34.89

Gene sequence:

>1731_bases
ATGGAAGCTAAAGGAAAAGTAGTAGGTGTTATTGGAAATTTGGTTACTATTGAAATGGTAGGTACGGTTTCCATGAATGA
AATTGTTTTTATTAAAACAGGTGGTCAGAGTTTAAAAGCTGAAATAATCCGTATTAGAGATGGAGAAGTTGATGCTCAAG
TGTTTGAAATGACAAGAGGAATTGCTGTTGGAGATGATGTTGAGTTTACAGATAAGCTTTTAACAGTTGAGTTAGGACCT
GGTCTTTTAAGTCAGGTGTATGATGGTCTTCAAAATCCATTACCAGAGCTTGCTACTAAGTGTGGTTTTTTTTTAGAGAG
GGGTTTATATTTAAGTGCTCTTGATAGAAATAAAAAGTGGAGTTTTAATGCAACTGCAAAAGTTGGAGATTTTGTTGTTG
CTGGAGATTTTCTTGGATTTGTCATCGAAGGTACCATTAATCATCAAATTATGGTTCCATTTGATAGGAGAGATTCTTAT
AGAATTATAGAAATAGTTGGTGATGGTGATTATACTGTAGATGATAAGATTGCTGTTATTGAAGATGATGCTGGGGGTAA
ACATATTATTACTATGTCGTTTCATTGGCCTGTGAAAGTTCCCGTTACTAGTTATAAAAAGAGACTTATTCCTAATGAGA
CCATGGTAACTCAAACAAGAATAATAGATACATTCTTTCCGGTTGCAAAGGGTGGTACATTTTGTATTCCTGGACCTTTT
GGTGCTGGTAAGACGGTTCTTCAACAGGTTACGAGTCGTAATGCTGATGTTGATATTGTAATTATTGCTGCTTGTGGTGA
GCGAGCAGGTGAGGTAGTAGAAACTCTGAAAGAGTTTCCTGAACTTACAGATCCAAGAACAGGTAAATCATTAATGGAGA
GAACATGTATTATTTGTAATACGTCTTCTATGCCCGTTGCTGCTCGTGAAGCATCAGTTTATACAGCTATTACTATTGGT
GAATATTATAGGCAAATGGGTCTTGATATACTCTTGTTGGCAGATTCAACTTCAAGGTGGGCTCAGGCTATGAGAGAGAT
GTCAGGTCGTCTTGAGGAAATACCAGGGGATGAGGCATTTCCAGCCTATCTTGAATCTGTTATTGCATCATTTTATGAAA
GAGCAGGTGTTGTTGTTTTAAATAATGGCAGTGTTGGATCTGTAACTGTGGGTGGTTCTGTTAGTCCTGCTGGGGGTAAT
TTTGAAGAACCAGTAACTCAAGCAACTTTGAAAGTGGTAGGAGCATTTCATGGTCTTACAAGAGAGAGATCAGATGCTAG
GAAATTTCCAGCAATTAATCCTCTTGACTCTTGGAGTAAATATAGAGGTGTAGTTGAATATGAGGCAACAGAATATGCAA
GGGCTTTTTTGGTTAAGGGAAATGAAGTTAATCAGATGATGAGAGTTGTTGGAGAAGATGGGGTGAGTATTGATGACTTT
GTTGTGTATTTGAAATCTGAACTTTTAGATTCATGTTATTTACAGCAAAATTCATTCGATAGTGTTGATGCTGCTGTGAG
TTTTGAGCGTCAAAATTATATGTTTAATATTCTTTATAAGATTTTACAATCAGATTTTAAATTTGAAAATAAATTGGAAG
CAAGAAGTTTTATAAATGATTTAAGACAAAATATTTTAGATATGAATCTTGCTCCCTTTAAGCAAGAAAAGTTTAATAAA
TTAGAAATTAATTTAAAAAATTTATTACGTTCTAAAAAATTGGATTTTTGA

Upstream 100 bases:

>100_bases
AGGAGAAGTCTCTTTAGAGAAGAGATAGGTGAGAAAAATTTTGATGATGTTTGTCAAAAATTAAGTATGAAAATAAGTAA
AAATTTTTGAAGGAATTTAA

Downstream 100 bases:

>100_bases
GGTGTGCAAATGAAGAGAGTATATAGTAAGATAGAATCTATTATTGGGAATGTAATAACTGTTATAGCAAAAAGTGTTAA
ATATGGAGAACTTGCCATTG

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MEAKGKVVGVIGNLVTIEMVGTVSMNEIVFIKTGGQSLKAEIIRIRDGEVDAQVFEMTRGIAVGDDVEFTDKLLTVELGP
GLLSQVYDGLQNPLPELATKCGFFLERGLYLSALDRNKKWSFNATAKVGDFVVAGDFLGFVIEGTINHQIMVPFDRRDSY
RIIEIVGDGDYTVDDKIAVIEDDAGGKHIITMSFHWPVKVPVTSYKKRLIPNETMVTQTRIIDTFFPVAKGGTFCIPGPF
GAGKTVLQQVTSRNADVDIVIIAACGERAGEVVETLKEFPELTDPRTGKSLMERTCIICNTSSMPVAAREASVYTAITIG
EYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGDEAFPAYLESVIASFYERAGVVVLNNGSVGSVTVGGSVSPAGGN
FEEPVTQATLKVVGAFHGLTRERSDARKFPAINPLDSWSKYRGVVEYEATEYARAFLVKGNEVNQMMRVVGEDGVSIDDF
VVYLKSELLDSCYLQQNSFDSVDAAVSFERQNYMFNILYKILQSDFKFENKLEARSFINDLRQNILDMNLAPFKQEKFNK
LEINLKNLLRSKKLDF

Sequences:

>Translated_576_residues
MEAKGKVVGVIGNLVTIEMVGTVSMNEIVFIKTGGQSLKAEIIRIRDGEVDAQVFEMTRGIAVGDDVEFTDKLLTVELGP
GLLSQVYDGLQNPLPELATKCGFFLERGLYLSALDRNKKWSFNATAKVGDFVVAGDFLGFVIEGTINHQIMVPFDRRDSY
RIIEIVGDGDYTVDDKIAVIEDDAGGKHIITMSFHWPVKVPVTSYKKRLIPNETMVTQTRIIDTFFPVAKGGTFCIPGPF
GAGKTVLQQVTSRNADVDIVIIAACGERAGEVVETLKEFPELTDPRTGKSLMERTCIICNTSSMPVAAREASVYTAITIG
EYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGDEAFPAYLESVIASFYERAGVVVLNNGSVGSVTVGGSVSPAGGN
FEEPVTQATLKVVGAFHGLTRERSDARKFPAINPLDSWSKYRGVVEYEATEYARAFLVKGNEVNQMMRVVGEDGVSIDDF
VVYLKSELLDSCYLQQNSFDSVDAAVSFERQNYMFNILYKILQSDFKFENKLEARSFINDLRQNILDMNLAPFKQEKFNK
LEINLKNLLRSKKLDF
>Mature_576_residues
MEAKGKVVGVIGNLVTIEMVGTVSMNEIVFIKTGGQSLKAEIIRIRDGEVDAQVFEMTRGIAVGDDVEFTDKLLTVELGP
GLLSQVYDGLQNPLPELATKCGFFLERGLYLSALDRNKKWSFNATAKVGDFVVAGDFLGFVIEGTINHQIMVPFDRRDSY
RIIEIVGDGDYTVDDKIAVIEDDAGGKHIITMSFHWPVKVPVTSYKKRLIPNETMVTQTRIIDTFFPVAKGGTFCIPGPF
GAGKTVLQQVTSRNADVDIVIIAACGERAGEVVETLKEFPELTDPRTGKSLMERTCIICNTSSMPVAAREASVYTAITIG
EYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGDEAFPAYLESVIASFYERAGVVVLNNGSVGSVTVGGSVSPAGGN
FEEPVTQATLKVVGAFHGLTRERSDARKFPAINPLDSWSKYRGVVEYEATEYARAFLVKGNEVNQMMRVVGEDGVSIDDF
VVYLKSELLDSCYLQQNSFDSVDAAVSFERQNYMFNILYKILQSDFKFENKLEARSFINDLRQNILDMNLAPFKQEKFNK
LEINLKNLLRSKKLDF

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=604, Percent_Identity=37.5827814569536, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI32189394, Length=296, Percent_Identity=25.6756756756757, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI19913428, Length=220, Percent_Identity=24.5454545454545, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI19913426, Length=220, Percent_Identity=23.6363636363636, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1790170, Length=362, Percent_Identity=24.0331491712707, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788251, Length=306, Percent_Identity=25.4901960784314, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790172, Length=248, Percent_Identity=23.7903225806452, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17565854, Length=524, Percent_Identity=39.8854961832061, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI25144756, Length=281, Percent_Identity=27.0462633451957, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17510931, Length=491, Percent_Identity=23.6252545824847, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17570191, Length=228, Percent_Identity=25.8771929824561, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71988080, Length=220, Percent_Identity=28.1818181818182, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71988063, Length=220, Percent_Identity=28.1818181818182, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71988074, Length=229, Percent_Identity=27.5109170305677, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320016, Length=259, Percent_Identity=42.8571428571429, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6322581, Length=342, Percent_Identity=25.7309941520468, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319603, Length=340, Percent_Identity=25.2941176470588, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24583992, Length=521, Percent_Identity=40.3071017274472, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24583988, Length=553, Percent_Identity=38.6980108499096, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24583986, Length=553, Percent_Identity=38.6980108499096, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24583984, Length=553, Percent_Identity=38.6980108499096, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI20129479, Length=521, Percent_Identity=38.7715930902111, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI281361666, Length=516, Percent_Identity=23.4496124031008, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646341, Length=516, Percent_Identity=23.4496124031008, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17136796, Length=516, Percent_Identity=23.4496124031008, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24638766, Length=341, Percent_Identity=24.9266862170088, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28574560, Length=333, Percent_Identity=27.3273273273273, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 63859; Mature: 63859

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAKGKVVGVIGNLVTIEMVGTVSMNEIVFIKTGGQSLKAEIIRIRDGEVDAQVFEMTRG
CCCCCCEEEEECCEEEEEEEECEEECCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHCC
IAVGDDVEFTDKLLTVELGPGLLSQVYDGLQNPLPELATKCGFFLERGLYLSALDRNKKW
CCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCC
SFNATAKVGDFVVAGDFLGFVIEGTINHQIMVPFDRRDSYRIIEIVGDGDYTVDDKIAVI
CCCCCCCCCCEEEECCCEEEEEEEECCCEEEEEECCCCCEEEEEEEECCCEEECCEEEEE
EDDAGGKHIITMSFHWPVKVPVTSYKKRLIPNETMVTQTRIIDTFFPVAKGGTFCIPGPF
ECCCCCCEEEEEEEECCEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCC
GAGKTVLQQVTSRNADVDIVIIAACGERAGEVVETLKEFPELTDPRTGKSLMERTCIICN
CCHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHCEEEEEC
TSSMPVAAREASVYTAITIGEYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGDEAF
CCCCCCEECCCCEEEEEEHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCHHHHCCCCCCC
PAYLESVIASFYERAGVVVLNNGSVGSVTVGGSVSPAGGNFEEPVTQATLKVVGAFHGLT
HHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RERSDARKFPAINPLDSWSKYRGVVEYEATEYARAFLVKGNEVNQMMRVVGEDGVSIDDF
CCCHHHHCCCCCCCCHHHHHHCCEEEECHHHHHEEEEECCCHHHHHHHHHCCCCCCHHHH
VVYLKSELLDSCYLQQNSFDSVDAAVSFERQNYMFNILYKILQSDFKFENKLEARSFIND
HHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LRQNILDMNLAPFKQEKFNKLEINLKNLLRSKKLDF
HHHHHHCCCCCCCCHHCCCEEEEEHHHHHHHHCCCC
>Mature Secondary Structure
MEAKGKVVGVIGNLVTIEMVGTVSMNEIVFIKTGGQSLKAEIIRIRDGEVDAQVFEMTRG
CCCCCCEEEEECCEEEEEEEECEEECCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHCC
IAVGDDVEFTDKLLTVELGPGLLSQVYDGLQNPLPELATKCGFFLERGLYLSALDRNKKW
CCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCC
SFNATAKVGDFVVAGDFLGFVIEGTINHQIMVPFDRRDSYRIIEIVGDGDYTVDDKIAVI
CCCCCCCCCCEEEECCCEEEEEEEECCCEEEEEECCCCCEEEEEEEECCCEEECCEEEEE
EDDAGGKHIITMSFHWPVKVPVTSYKKRLIPNETMVTQTRIIDTFFPVAKGGTFCIPGPF
ECCCCCCEEEEEEEECCEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCC
GAGKTVLQQVTSRNADVDIVIIAACGERAGEVVETLKEFPELTDPRTGKSLMERTCIICN
CCHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHCEEEEEC
TSSMPVAAREASVYTAITIGEYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGDEAF
CCCCCCEECCCCEEEEEEHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCHHHHCCCCCCC
PAYLESVIASFYERAGVVVLNNGSVGSVTVGGSVSPAGGNFEEPVTQATLKVVGAFHGLT
HHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RERSDARKFPAINPLDSWSKYRGVVEYEATEYARAFLVKGNEVNQMMRVVGEDGVSIDDF
CCCHHHHCCCCCCCCHHHHHHCCEEEECHHHHHEEEEECCCHHHHHHHHHCCCCCCHHHH
VVYLKSELLDSCYLQQNSFDSVDAAVSFERQNYMFNILYKILQSDFKFENKLEARSFIND
HHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LRQNILDMNLAPFKQEKFNKLEINLKNLLRSKKLDF
HHHHHHCCCCCCCCHHCCCEEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA