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The map label for this gene is lacZ [H]

Identifier: 308535400

GI number: 308535400

Start: 4558640

End: 4559581

Strand: Direct

Name: lacZ [H]

Synonym: NA

Alternate gene names: 308535400

Gene position: 4558640-4559581 (Clockwise)

Preceding gene: 197120375

Following gene: 197120376

Centisome position: 98.78

GC content: 64.44

Gene sequence:

>942_bases
ATGGACTATCCCCGCCCGCAATTGCAGCGCCCCAACTGGCATACGCTCGACGGCCAGTGGCACTTCACCTTCGACGACGA
TCTCTCTTACAACTTGCCTGTGGACGTGAAAGAGTGGCCCCTCACCATTGAGGTACCCTTCGCGCCCGAAAGCCAGGCAA
GCGGCATCGGTGACACCTCCTTTCACCATGCCTGCTGGTATCAGCGCGAGTTTTACTACAACGCGACCGAAGGGAAAAAG
GTGCTGCTCCATTTCGGCGCCGTCGATTACCTGGCGCACGTCTGGGTCAACGACATGCTGGTGGCGCGGCACCGCGGCGG
CTTCACCCCGTTCAGCGCCGACATCACCCATGCCCTCGATCCTTCCGGGCGCCAGGTCGTGACCGTGCGGGCCGAGGACG
ACCCGGAGGATCTGGAGAAGCCGCGCGGAAAGCAGGACTGGAAGCTGGAGCCGCACGCGATCTGGTACTACCGCACCACC
GGCATCTGGCAGACCGTCTGGCTGGAATCGGTCCCCGAGACCTACTTGAAGAAGCTGCGCTGGTCGCCGCACCTGGAGCG
CTGGGAGGTGGGGATCGAGGCCTTCATCGTGGGTCCCATCGCGGACCAGATGGAAGTGAACGTGCGGCTTTCCTTCAGCG
ACCAGCTCCTGGTCGAGGACCGCTACCGGGTGATCCACGGCGAGGTGCACCGGCGCATCGCCCTCTCCGACCCCGGGATC
GACGACTTCAGAAACGACCTTCTCTGGTCGCCGGAGCACCCGAGGCTGATCCACGCCGACATCAAGCTGATGCAGGGGGG
CGAGGTGATCGACGAGATCACCTCCTACACCGCGCTCCGTTCCGCCAAGGTGCACCGGGACCGGTTCCTCCTGAACGGGC
GGCTCTACCCGCTCAGGCTGGTGCTGGACCAGGGGTACTGGCCGGAGACGCTGATGACCCCC

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: glycoside hydrolase

Products: NA

Alternate protein names: Beta-gal; Lactase [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:
NA

Sequences:

>Translated_314_residues
MDYPRPQLQRPNWHTLDGQWHFTFDDDLSYNLPVDVKEWPLTIEVPFAPESQASGIGDTSFHHACWYQREFYYNATEGKK
VLLHFGAVDYLAHVWVNDMLVARHRGGFTPFSADITHALDPSGRQVVTVRAEDDPEDLEKPRGKQDWKLEPHAIWYYRTT
GIWQTVWLESVPETYLKKLRWSPHLERWEVGIEAFIVGPIADQMEVNVRLSFSDQLLVEDRYRVIHGEVHRRIALSDPGI
DDFRNDLLWSPEHPRLIHADIKLMQGGEVIDEITSYTALRSAKVHRDRFLLNGRLYPLRLVLDQGYWPETLMTP
>Mature_314_residues
MDYPRPQLQRPNWHTLDGQWHFTFDDDLSYNLPVDVKEWPLTIEVPFAPESQASGIGDTSFHHACWYQREFYYNATEGKK
VLLHFGAVDYLAHVWVNDMLVARHRGGFTPFSADITHALDPSGRQVVTVRAEDDPEDLEKPRGKQDWKLEPHAIWYYRTT
GIWQTVWLESVPETYLKKLRWSPHLERWEVGIEAFIVGPIADQMEVNVRLSFSDQLLVEDRYRVIHGEVHRRIALSDPGI
DDFRNDLLWSPEHPRLIHADIKLMQGGEVIDEITSYTALRSAKVHRDRFLLNGRLYPLRLVLDQGYWPETLMTP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787903, Length=289, Percent_Identity=24.5674740484429, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24655438, Length=330, Percent_Identity=23.030303030303, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI62471735, Length=330, Percent_Identity=23.030303030303, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922582, Length=330, Percent_Identity=23.030303030303, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 36767; Mature: 36767

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYPRPQLQRPNWHTLDGQWHFTFDDDLSYNLPVDVKEWPLTIEVPFAPESQASGIGDTS
CCCCCCCCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
FHHACWYQREFYYNATEGKKVLLHFGAVDYLAHVWVNDMLVARHRGGFTPFSADITHALD
CHHHEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHEEEEHHCCCCCCCCCCCCCCCC
PSGRQVVTVRAEDDPEDLEKPRGKQDWKLEPHAIWYYRTTGIWQTVWLESVPETYLKKLR
CCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEHHHHHCCHHHHHHHC
WSPHLERWEVGIEAFIVGPIADQMEVNVRLSFSDQLLVEDRYRVIHGEVHRRIALSDPGI
CCCCHHHHHCCEEEEEECCCCCCEEEEEEEECCCCEEECCHHHEEECHHHEEEEECCCCH
DDFRNDLLWSPEHPRLIHADIKLMQGGEVIDEITSYTALRSAKVHRDRFLLNGRLYPLRL
HHHHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEE
VLDQGYWPETLMTP
EEECCCCCCCCCCC
>Mature Secondary Structure
MDYPRPQLQRPNWHTLDGQWHFTFDDDLSYNLPVDVKEWPLTIEVPFAPESQASGIGDTS
CCCCCCCCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
FHHACWYQREFYYNATEGKKVLLHFGAVDYLAHVWVNDMLVARHRGGFTPFSADITHALD
CHHHEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHEEEEHHCCCCCCCCCCCCCCCC
PSGRQVVTVRAEDDPEDLEKPRGKQDWKLEPHAIWYYRTTGIWQTVWLESVPETYLKKLR
CCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEHHHHHCCHHHHHHHC
WSPHLERWEVGIEAFIVGPIADQMEVNVRLSFSDQLLVEDRYRVIHGEVHRRIALSDPGI
CCCCHHHHHCCEEEEEECCCCCCEEEEEEEECCCCEEECCHHHEEECHHHEEEEECCCCH
DDFRNDLLWSPEHPRLIHADIKLMQGGEVIDEITSYTALRSAKVHRDRFLLNGRLYPLRL
HHHHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEE
VLDQGYWPETLMTP
EEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA