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The map label for this gene is ygcA [C]

Identifier: 308535284

GI number: 308535284

Start: 2370899

End: 2372233

Strand: Direct

Name: ygcA [C]

Synonym: NA

Alternate gene names: 308535284

Gene position: 2370899-2372233 (Clockwise)

Preceding gene: 197118439

Following gene: 197118441

Centisome position: 51.37

GC content: 66.07

Gene sequence:

>1335_bases
TTGTGGTCGGCGGCTACCGTGGCTGAGGCGGTTGTCGAAATCGAGAGGCTATGCTACGGCGGCGCGGGCTTTGGCCGCAT
CGACGGCAAGGCCTGCTTCGTTCCGCTCACCGCGCCGGGCGACAAGGCCCGGGTCCGGGTGGTCAAGGAGAAGCGCTCCT
TCGCCGAGGCCGAGGTGGTCGAGCTCTTGGAGCCTTCGCCGCTGCGCACCGACCCCGCCTGTCCCTATTTCGGGGTCTGC
GGCGGATGCGATTGGCAGCATCTTCCCTATGCCGAGCAGTTGAAGCAAAAAGGGGAGATCTTCGCCGACACGCTGGCGCG
CATCGGGAAGGTGCCGCGCGAGCTGGTTTTGCCGGTTTCCCCCTCGCCTGAGTGCTTCGGTTACCGCTCGCGCATCCAGC
TCAAAGTCGCCCGTAAAGGCGGCATCCCGACGCTGGGGTTTTTCAAGCGCGGCTCGCACGACGTGGTCGATCTCGCCGCG
GGGTGCGCCCTGGCTGCGCCACTTTTGAACCAGGCGCTGGCCGAGGTCAGGGGGATTTTGCCGAGGCTGCCGCAGCTTGA
GGGGATAACCCAGGTGGATCTCGCCATGGGCGACGACGGGGAGTCCATCGCGGTCTTCCACTACCGCGGGAAAGACGCCG
CCTCTCTTTTGGATTGCCTTCTTGCCGCCCGACCTGAGCTTCCTTCTGTAACTGGTGCTTACGTGAAGACCGGGGAGAAG
GGGGAAATGAGCGCCGTCTTCGGCGTCGACTCCCTGAGCTACGGGGTTCCCGCCGGGCTCTTCCCCGGGTCGCGCGAGGT
GCGGCTTCGCTTCAGCCGCGGTGGGTTCTCCCAGGTCAACTATCGTCAGAACCTGGAGCTGATCAAGACGGTGGGGGAGT
GGGGCGCGCTGCGGGAAGGAGCCCGGGTGCTCGACCTTTACTGCGGCAACGGCAACATCTCGGTTCCCATCGCGCCTTTG
GTCGGCGAAGTGGTCGGGGTGGAAGGGTACGCTCCCTCGATCGTCGACGCCGCGGCCAACGCCGAGGCAAACGGCGCCCT
CAACGCAAGATACCTCGTGGGTGACGCGGCGCTTTCGGTGCGGCGGCTGGCAAAGCGCAAGGAAAAGTTCGACCTGGTCG
TCCTCGACCCGCCGCGCGCCGGCGCCGAAGCTGCCGGGGAGCTGGCTATTTTGGCGCCGGAAAGAATCCTCTATGTATCC
TGCGACCCCGCCACCCTGGCGCGCGACCTGGGCCAGCTTTGCGGGGCCGGGTACCGGGTCGCCCGCTCCAAGCCGGTGGA
CATGTTCCCGCAGACCTACCACCTGGAGAGCGTGACCGAACTGATTCGGGATTGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: RNA methyltransferase, TrmA family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:
NA

Sequences:

>Translated_444_residues
MWSAATVAEAVVEIERLCYGGAGFGRIDGKACFVPLTAPGDKARVRVVKEKRSFAEAEVVELLEPSPLRTDPACPYFGVC
GGCDWQHLPYAEQLKQKGEIFADTLARIGKVPRELVLPVSPSPECFGYRSRIQLKVARKGGIPTLGFFKRGSHDVVDLAA
GCALAAPLLNQALAEVRGILPRLPQLEGITQVDLAMGDDGESIAVFHYRGKDAASLLDCLLAARPELPSVTGAYVKTGEK
GEMSAVFGVDSLSYGVPAGLFPGSREVRLRFSRGGFSQVNYRQNLELIKTVGEWGALREGARVLDLYCGNGNISVPIAPL
VGEVVGVEGYAPSIVDAAANAEANGALNARYLVGDAALSVRRLAKRKEKFDLVVLDPPRAGAEAAGELAILAPERILYVS
CDPATLARDLGQLCGAGYRVARSKPVDMFPQTYHLESVTELIRD
>Mature_444_residues
MWSAATVAEAVVEIERLCYGGAGFGRIDGKACFVPLTAPGDKARVRVVKEKRSFAEAEVVELLEPSPLRTDPACPYFGVC
GGCDWQHLPYAEQLKQKGEIFADTLARIGKVPRELVLPVSPSPECFGYRSRIQLKVARKGGIPTLGFFKRGSHDVVDLAA
GCALAAPLLNQALAEVRGILPRLPQLEGITQVDLAMGDDGESIAVFHYRGKDAASLLDCLLAARPELPSVTGAYVKTGEK
GEMSAVFGVDSLSYGVPAGLFPGSREVRLRFSRGGFSQVNYRQNLELIKTVGEWGALREGARVLDLYCGNGNISVPIAPL
VGEVVGVEGYAPSIVDAAANAEANGALNARYLVGDAALSVRRLAKRKEKFDLVVLDPPRAGAEAAGELAILAPERILYVS
CDPATLARDLGQLCGAGYRVARSKPVDMFPQTYHLESVTELIRD

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=180, Percent_Identity=36.1111111111111, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI51173878, Length=180, Percent_Identity=36.1111111111111, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI269784680, Length=415, Percent_Identity=24.0963855421687, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI269784676, Length=415, Percent_Identity=24.0963855421687, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI20149688, Length=415, Percent_Identity=24.0963855421687, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI269784678, Length=230, Percent_Identity=27.8260869565217, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789148, Length=436, Percent_Identity=34.8623853211009, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1790403, Length=378, Percent_Identity=26.4550264550265, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787083, Length=386, Percent_Identity=25.1295336787565, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997438, Length=168, Percent_Identity=32.7380952380952, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666579, Length=489, Percent_Identity=25.1533742331288, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 47496; Mature: 47496

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50926 TRAM ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSAATVAEAVVEIERLCYGGAGFGRIDGKACFVPLTAPGDKARVRVVKEKRSFAEAEVV
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHEEEHHHHHHHHHHHHH
ELLEPSPLRTDPACPYFGVCGGCDWQHLPYAEQLKQKGEIFADTLARIGKVPRELVLPVS
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHEEECCC
PSPECFGYRSRIQLKVARKGGIPTLGFFKRGSHDVVDLAAGCALAAPLLNQALAEVRGIL
CCCHHCCCCCEEEEEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PRLPQLEGITQVDLAMGDDGESIAVFHYRGKDAASLLDCLLAARPELPSVTGAYVKTGEK
HCCCCCCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHEECCCC
GEMSAVFGVDSLSYGVPAGLFPGSREVRLRFSRGGFSQVNYRQNLELIKTVGEWGALREG
CCEEEEEECCHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCC
ARVLDLYCGNGNISVPIAPLVGEVVGVEGYAPSIVDAAANAEANGALNARYLVGDAALSV
CEEEEEEECCCCEEEEHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCEEEEECHHHHHH
RRLAKRKEKFDLVVLDPPRAGAEAAGELAILAPERILYVSCDPATLARDLGQLCGAGYRV
HHHHHHHHHCCEEEECCCCCCCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHHCCCEEE
ARSKPVDMFPQTYHLESVTELIRD
CCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MWSAATVAEAVVEIERLCYGGAGFGRIDGKACFVPLTAPGDKARVRVVKEKRSFAEAEVV
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHEEEHHHHHHHHHHHHH
ELLEPSPLRTDPACPYFGVCGGCDWQHLPYAEQLKQKGEIFADTLARIGKVPRELVLPVS
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHEEECCC
PSPECFGYRSRIQLKVARKGGIPTLGFFKRGSHDVVDLAAGCALAAPLLNQALAEVRGIL
CCCHHCCCCCEEEEEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PRLPQLEGITQVDLAMGDDGESIAVFHYRGKDAASLLDCLLAARPELPSVTGAYVKTGEK
HCCCCCCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHEECCCC
GEMSAVFGVDSLSYGVPAGLFPGSREVRLRFSRGGFSQVNYRQNLELIKTVGEWGALREG
CCEEEEEECCHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCC
ARVLDLYCGNGNISVPIAPLVGEVVGVEGYAPSIVDAAANAEANGALNARYLVGDAALSV
CEEEEEEECCCCEEEEHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCEEEEECHHHHHH
RRLAKRKEKFDLVVLDPPRAGAEAAGELAILAPERILYVSCDPATLARDLGQLCGAGYRV
HHHHHHHHHCCEEEECCCCCCCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHHCCCEEE
ARSKPVDMFPQTYHLESVTELIRD
CCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA