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The map label for this gene is polC [H]

Identifier: 308535281

GI number: 308535281

Start: 2326345

End: 2327283

Strand: Direct

Name: polC [H]

Synonym: NA

Alternate gene names: 308535281

Gene position: 2326345-2327283 (Clockwise)

Preceding gene: 197118402

Following gene: 197118404

Centisome position: 50.41

GC content: 62.62

Gene sequence:

>939_bases
ATGAAGGGAGCTAAAAAGAAGGAGTTCAGCATGAACGCGCTGGAGATTGAGGTGGCCATCGCCGCGCTTCATTCCACAGG
GGACTACCTGGTACTGCGGCGCCTGAACCTCGCGCGCGACGCTCGCCTCGCCCGCAAGGCCCCGGAGTGCTGCCAGGTCG
CCCTTTGCCTGGACACCGAGACCACCGGACTCGACTATAAGCGGGACAAGGTCATCGAACTGGGGATCGTCGCTTTCGAG
TACGACCCCGAGACCGGCGAGATCTTCAGGATCTCCGAGCGCTACTCCGGCTTTGAAGATCCGGGGTTCCCCATCCCGGA
AGAGGTGAAGGAGATTACCGGCATCTCGGACGACATGGTGCGCGGGCAGGCGTTCGACGACGCCTTCATCAACCTCCTGG
CCGAGAAGTCCCACATGGTGATCGCCCATAACGCCGCCTTCGACAGGAAGTTCGTCGAGGCGCGGTTCCCGGCCTTCACC
AAGCTCCCCTGGGCCTGCACCGTGTCGCAGATCGACTGGGGGGCGGAGCGGGTGTCTTCGCGTACGCTGGAATATCTCCT
TTTCAAGACCGCTTCTCTCACCATCAACGCACACCGTGCGCTCGACGACGCCGAGGGGGTGTTGGGGCTTTTGCTGGAGC
GGCTTCCGGTTACCGGCGCGCCCATCTTCCAGACTTTATTGAAGAGAGCGCACGAGGTCACCTCGCGGCTTTATGCCGTC
TCCGCACCCTTCGACAAGAAGGATCTTCTCAAGGACCGCGGCTATCGCTGGAGCGACGGGTCACAGGGGGGGAGCAAGGC
ATGGTGGCGCGATGTGCCTGCCGAGGCCGAGCCGGAGGAGCTCGCCTATCTGGCGAACGAGATCTATCCCAGGGGGAACA
CGAGCGCCGTGCAGATAATGAGGTGCGACGCGTATGCGAGGTTCTCCGCGCGGGAGTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: 3'-to-5' exonuclease

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:
NA

Sequences:

>Translated_312_residues
MKGAKKKEFSMNALEIEVAIAALHSTGDYLVLRRLNLARDARLARKAPECCQVALCLDTETTGLDYKRDKVIELGIVAFE
YDPETGEIFRISERYSGFEDPGFPIPEEVKEITGISDDMVRGQAFDDAFINLLAEKSHMVIAHNAAFDRKFVEARFPAFT
KLPWACTVSQIDWGAERVSSRTLEYLLFKTASLTINAHRALDDAEGVLGLLLERLPVTGAPIFQTLLKRAHEVTSRLYAV
SAPFDKKDLLKDRGYRWSDGSQGGSKAWWRDVPAEAEPEELAYLANEIYPRGNTSAVQIMRCDAYARFSARE
>Mature_312_residues
MKGAKKKEFSMNALEIEVAIAALHSTGDYLVLRRLNLARDARLARKAPECCQVALCLDTETTGLDYKRDKVIELGIVAFE
YDPETGEIFRISERYSGFEDPGFPIPEEVKEITGISDDMVRGQAFDDAFINLLAEKSHMVIAHNAAFDRKFVEARFPAFT
KLPWACTVSQIDWGAERVSSRTLEYLLFKTASLTINAHRALDDAEGVLGLLLERLPVTGAPIFQTLLKRAHEVTSRLYAV
SAPFDKKDLLKDRGYRWSDGSQGGSKAWWRDVPAEAEPEELAYLANEIYPRGNTSAVQIMRCDAYARFSARE

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 35035; Mature: 35035

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGAKKKEFSMNALEIEVAIAALHSTGDYLVLRRLNLARDARLARKAPECCQVALCLDTE
CCCCCCCCCCCCCEEEEEEEEEHHCCCCEEEEEHHHHHHHHHHHHCCHHHHEEEEEECCC
TTGLDYKRDKVIELGIVAFEYDPETGEIFRISERYSGFEDPGFPIPEEVKEITGISDDMV
CCCCCCCCCCEEEEEEEEEEECCCCCCEEEEHHHCCCCCCCCCCCHHHHHHHCCCCHHHH
RGQAFDDAFINLLAEKSHMVIAHNAAFDRKFVEARFPAFTKLPWACTVSQIDWGAERVSS
CCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCHHCCCCEEEHHHCCCCHHHHHH
RTLEYLLFKTASLTINAHRALDDAEGVLGLLLERLPVTGAPIFQTLLKRAHEVTSRLYAV
HHHHHHHHHHHEEEEEHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEE
SAPFDKKDLLKDRGYRWSDGSQGGSKAWWRDVPAEAEPEELAYLANEIYPRGNTSAVQIM
ECCCCHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEE
RCDAYARFSARE
EECCHHCCCCCC
>Mature Secondary Structure
MKGAKKKEFSMNALEIEVAIAALHSTGDYLVLRRLNLARDARLARKAPECCQVALCLDTE
CCCCCCCCCCCCCEEEEEEEEEHHCCCCEEEEEHHHHHHHHHHHHCCHHHHEEEEEECCC
TTGLDYKRDKVIELGIVAFEYDPETGEIFRISERYSGFEDPGFPIPEEVKEITGISDDMV
CCCCCCCCCCEEEEEEEEEEECCCCCCEEEEHHHCCCCCCCCCCCHHHHHHHCCCCHHHH
RGQAFDDAFINLLAEKSHMVIAHNAAFDRKFVEARFPAFTKLPWACTVSQIDWGAERVSS
CCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCHHCCCCEEEHHHCCCCHHHHHH
RTLEYLLFKTASLTINAHRALDDAEGVLGLLLERLPVTGAPIFQTLLKRAHEVTSRLYAV
HHHHHHHHHHHEEEEEHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEE
SAPFDKKDLLKDRGYRWSDGSQGGSKAWWRDVPAEAEPEELAYLANEIYPRGNTSAVQIM
ECCCCHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEE
RCDAYARFSARE
EECCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA