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The map label for this gene is ctaB [H]

Identifier: 308535146

GI number: 308535146

Start: 56404

End: 57222

Strand: Direct

Name: ctaB [H]

Synonym: NA

Alternate gene names: 308535146

Gene position: 56404-57222 (Clockwise)

Preceding gene: 197116446

Following gene: 197116448

Centisome position: 1.22

GC content: 66.54

Gene sequence:

>819_bases
GTGAGAATACTGGCGCGACTTTTTCGGCTGCCGCTAGCGCTCATGAACGGGGCCGCTGCGGCGGCGGGTTACCTGCTCTT
CCCCTCTCCGGCCCAGCGCCCTACCCTCTTGGCCGTCTTCCTGGGTGTGGCGCTTTTGGCCGCGGCAGGCTCCGCGCTGA
ACCAGGTCATGGAGCGGGACCTCGATGCGCTTATGCGGCGCACCTGCGACCGCCCTCTTCCCACCGGAAAACTCACACCG
GCCGCCGCCCTCCTGGCGGGACTCGCTGCGCTTTCGGCAGGCGCCGCCCTTCTTTCCCTCGTGGCCGGTACGGTTCCGGC
CGCCGTCTCTCTTTTCACCCTCCTCTGGTACCTGGCGCTGTACACCCCCCTGAAGCGGGTCAGTTCGCTGGCGCTTCTGG
TCGGAGGGTTGTGCGGGTGCGGCGCGCCGCTGGTCGGGTGGAGCGCCGCCGGCGGGGGAATCGGGGAGTTTCCGGTCATC
CTGCTGGCCGGGGTCATTTACCTCTGGCAGGTGCCGCATTTCTGGCAGTTGCAGCGAAAACATGCCGACGACTATCGGCG
CGCAGGTTTCCCCGTCTTCACGCCTCCCGCCGGCGCCGACGGTTGCGCGCCGCTTTGCCGGCTCTGGATGGCGGCCATGG
TCGCCGGGACCTTGATGCTTCCGCTCTTCGGCGTCGTCCGGGCCACGCCCCTTATCTGCACCATACTGCTGCCGGTACCC
CTCCTGTTCTGGTCCAGGAAGCGTTGGGAACCCTTCGCCGGTTTGGTGCTTCATTGCTACCCGCTACTGGTCACCCTTGC
TATATTCGGTGCTAAATGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: cytochrome oxidase assembly polyprenyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:
NA

Sequences:

>Translated_272_residues
MRILARLFRLPLALMNGAAAAAGYLLFPSPAQRPTLLAVFLGVALLAAAGSALNQVMERDLDALMRRTCDRPLPTGKLTP
AAALLAGLAALSAGAALLSLVAGTVPAAVSLFTLLWYLALYTPLKRVSSLALLVGGLCGCGAPLVGWSAAGGGIGEFPVI
LLAGVIYLWQVPHFWQLQRKHADDYRRAGFPVFTPPAGADGCAPLCRLWMAAMVAGTLMLPLFGVVRATPLICTILLPVP
LLFWSRKRWEPFAGLVLHCYPLLVTLAIFGAK
>Mature_272_residues
MRILARLFRLPLALMNGAAAAAGYLLFPSPAQRPTLLAVFLGVALLAAAGSALNQVMERDLDALMRRTCDRPLPTGKLTP
AAALLAGLAALSAGAALLSLVAGTVPAAVSLFTLLWYLALYTPLKRVSSLALLVGGLCGCGAPLVGWSAAGGGIGEFPVI
LLAGVIYLWQVPHFWQLQRKHADDYRRAGFPVFTPPAGADGCAPLCRLWMAAMVAGTLMLPLFGVVRATPLICTILLPVP
LLFWSRKRWEPFAGLVLHCYPLLVTLAIFGAK

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=188, Percent_Identity=36.1702127659575, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1786631, Length=211, Percent_Identity=30.3317535545024, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71998235, Length=187, Percent_Identity=34.2245989304813, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6325085, Length=174, Percent_Identity=30.4597701149425, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19921064, Length=168, Percent_Identity=35.7142857142857, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 28750; Mature: 28750

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILARLFRLPLALMNGAAAAAGYLLFPSPAQRPTLLAVFLGVALLAAAGSALNQVMERD
CHHHHHHHHHHHHHHCCHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDALMRRTCDRPLPTGKLTPAAALLAGLAALSAGAALLSLVAGTVPAAVSLFTLLWYLAL
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTPLKRVSSLALLVGGLCGCGAPLVGWSAAGGGIGEFPVILLAGVIYLWQVPHFWQLQRK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
HADDYRRAGFPVFTPPAGADGCAPLCRLWMAAMVAGTLMLPLFGVVRATPLICTILLPVP
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLFWSRKRWEPFAGLVLHCYPLLVTLAIFGAK
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA