Click here to switch to the map view.

The map label for this gene is coxB [H]

Identifier: 197116446

GI number: 197116446

Start: 55502

End: 56407

Strand: Direct

Name: coxB [H]

Synonym: Gbem_0046

Alternate gene names: 197116446

Gene position: 55502-56407 (Clockwise)

Preceding gene: 197116445

Following gene: 308535146

Centisome position: 1.2

GC content: 60.82

Gene sequence:

>906_bases
GTGGAAAATCAGCTAATTACATCGACGCAACAAGCCGTAGACCCGGTATTCACCTTCCTCTTTGGCGCCTGCCTGGTGCT
GCTTTTGGGGATCACCGCGACCATGGTTTATTTCGTGGTCCGCTACCGCCGCTCCAAGAACCCGGAGCCGACCTCGCAGG
TCTCGGGGAGTCCGCTTCTGGAGGTGGTCTGGACCGTCCTCCCCACCATCCTGGTGATGGGGATGTTCTACTACGGCTGG
ACTAGCTATCTGTCGCTCAGGACGGTGCCGAAAAACGCGATGCAGGTTAAGGCCGAGGCGAGGATGTGGTCCTGGAACTT
CGTCTACGACAACGGCAAGCAAAGCGGCAAGCTCTACGTCCCGGTAGGGAGGGCGGTACAGGTGAACCTTGAGTCGAAGG
ACGTGGTGCACGGCTTCTACGTCCCCGCCTTCAAGATCAAGCGGGACGTGGTCCCGGGTATGAAGAACCACGTCTGGTTC
GTGGCGACGAGCCCAGGCACCTACGACCTCTTCTGTTCGCAGTACTGCGGCACCGGCCACTCCGCCATGATCACCACGGT
CGAAGCCCTCCCCCCGGCGCAGTTTGCCGCCTGGCTGCAGCAGACAGCCGCAGGGGGCGCGGCTCAGGGACAGGCGCTTT
TGGAAAAATACGGCTGCCTCGGCTGCCACTCGCTGGACGGTACCAGGAAAGTCGGGCCCACCTTCAAGGGGCTCTACGGA
AGCCAGGTCAAGGTCGAAAGGGAAAAGAAAGAGGAAACGGTCACAGCTGATGACGTCTACCTGCGCGAATCCATACTCAA
TCCCGCGGCCGCCATCGTGGACGACTACCCCGCGGTGATGCCCCCCTCCACCATGCCTGAGGCGGATTTGAAGGCGGTGA
TCGAGTACCTGAAGGGGTTGAAGTGA

Upstream 100 bases:

>100_bases
GCCGCGGCTATTCCGCATCATCCTGTTCGTGGCCCTCTTCACCCTGGCCGGATTCATCGGGGGCACCTTTTTCGACGTAC
TCTACCGTTAGAGGGGCATC

Downstream 100 bases:

>100_bases
GAATACTGGCGCGACTTTTTCGGCTGCCGCTAGCGCTCATGAACGGGGCCGCTGCGGCGGCGGGTTACCTGCTCTTCCCC
TCTCCGGCCCAGCGCCCTAC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MENQLITSTQQAVDPVFTFLFGACLVLLLGITATMVYFVVRYRRSKNPEPTSQVSGSPLLEVVWTVLPTILVMGMFYYGW
TSYLSLRTVPKNAMQVKAEARMWSWNFVYDNGKQSGKLYVPVGRAVQVNLESKDVVHGFYVPAFKIKRDVVPGMKNHVWF
VATSPGTYDLFCSQYCGTGHSAMITTVEALPPAQFAAWLQQTAAGGAAQGQALLEKYGCLGCHSLDGTRKVGPTFKGLYG
SQVKVEREKKEETVTADDVYLRESILNPAAAIVDDYPAVMPPSTMPEADLKAVIEYLKGLK

Sequences:

>Translated_301_residues
MENQLITSTQQAVDPVFTFLFGACLVLLLGITATMVYFVVRYRRSKNPEPTSQVSGSPLLEVVWTVLPTILVMGMFYYGW
TSYLSLRTVPKNAMQVKAEARMWSWNFVYDNGKQSGKLYVPVGRAVQVNLESKDVVHGFYVPAFKIKRDVVPGMKNHVWF
VATSPGTYDLFCSQYCGTGHSAMITTVEALPPAQFAAWLQQTAAGGAAQGQALLEKYGCLGCHSLDGTRKVGPTFKGLYG
SQVKVEREKKEETVTADDVYLRESILNPAAAIVDDYPAVMPPSTMPEADLKAVIEYLKGLK
>Mature_301_residues
MENQLITSTQQAVDPVFTFLFGACLVLLLGITATMVYFVVRYRRSKNPEPTSQVSGSPLLEVVWTVLPTILVMGMFYYGW
TSYLSLRTVPKNAMQVKAEARMWSWNFVYDNGKQSGKLYVPVGRAVQVNLESKDVVHGFYVPAFKIKRDVVPGMKNHVWF
VATSPGTYDLFCSQYCGTGHSAMITTVEALPPAQFAAWLQQTAAGGAAQGQALLEKYGCLGCHSLDGTRKVGPTFKGLYG
SQVKVEREKKEETVTADDVYLRESILNPAAAIVDDYPAVMPPSTMPEADLKAVIEYLKGLK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=165, Percent_Identity=26.0606060606061, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6226540, Length=205, Percent_Identity=27.3170731707317, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 33218; Mature: 33218

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQLITSTQQAVDPVFTFLFGACLVLLLGITATMVYFVVRYRRSKNPEPTSQVSGSPLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHH
EVVWTVLPTILVMGMFYYGWTSYLSLRTVPKNAMQVKAEARMWSWNFVYDNGKQSGKLYV
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHEEEEEEEEECCCCCCEEEE
PVGRAVQVNLESKDVVHGFYVPAFKIKRDVVPGMKNHVWFVATSPGTYDLFCSQYCGTGH
EECCEEEEECCCCCCCCEEECCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCC
SAMITTVEALPPAQFAAWLQQTAAGGAAQGQALLEKYGCLGCHSLDGTRKVGPTFKGLYG
CHHEEEHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SQVKVEREKKEETVTADDVYLRESILNPAAAIVDDYPAVMPPSTMPEADLKAVIEYLKGL
CCEEEEHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure
MENQLITSTQQAVDPVFTFLFGACLVLLLGITATMVYFVVRYRRSKNPEPTSQVSGSPLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHH
EVVWTVLPTILVMGMFYYGWTSYLSLRTVPKNAMQVKAEARMWSWNFVYDNGKQSGKLYV
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHEEEEEEEEECCCCCCEEEE
PVGRAVQVNLESKDVVHGFYVPAFKIKRDVVPGMKNHVWFVATSPGTYDLFCSQYCGTGH
EECCEEEEECCCCCCCCEEECCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCC
SAMITTVEALPPAQFAAWLQQTAAGGAAQGQALLEKYGCLGCHSLDGTRKVGPTFKGLYG
CHHEEEHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SQVKVEREKKEETVTADDVYLRESILNPAAAIVDDYPAVMPPSTMPEADLKAVIEYLKGL
CCEEEEHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]