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The map label for this gene is nodV [H]

Identifier: 197120400

GI number: 197120400

Start: 4592364

End: 4594223

Strand: Direct

Name: nodV [H]

Synonym: Gbem_4041

Alternate gene names: 197120400

Gene position: 4592364-4594223 (Clockwise)

Preceding gene: 197120399

Following gene: 197120402

Centisome position: 99.51

GC content: 60.81

Gene sequence:

>1860_bases
ATGAAAAACGGGAGTCCCACCGACAAACAGGCCCTGGAGCAGCAGTTGACTGCCCTGCGCAGGGAAAACGAGGAGCTGGC
CCAACAGGTCAAACGGCTGATCAGGGCCGAAGGGAAGCTCTACGAGTACCAGCAGGTGCTCGACCTCCAGTTGAACGAGT
ACAAAGGGCTTTACGACCTGAGCAGGAGGCTGAGCGGGAGCTTCTACATCCAGGGCCTGTTCCGCGAGACCGTGCAGTAC
GTGGTCCAGCAGCTGGAGTACGAACGGGCTATCCTGCTCCGCCGCGAAGAAACGGTTACCTACCGCGTCTTGGCCCTTGA
CGGCTACTACGATCCAAGCGAAAAAGAACAGGCCGCCGCCATTACCATGAAGTACGGCGCCCCCTGCCTCTCCCCCCTTC
TAGCAGGCAGGGAGCATGTCACCTGCACCGCAACCTCGACGGAACCCGGAAACGGATGCCGACGGCGCCTACTGATGGAC
GAGTTCCTGGTATACCCCCTAGGCCACGACGAGGTCCCCCACGCCCTGCTGGTGGTCGGCAACACCGCGACCAATGCACC
CTTTCACCGGCGGGTGCAGGAAAGCGACCAGGCGCTCCTCAGCATGGGAAACCTGGTCGGTCTCGTATCATCCATTCTGG
ATACCCACATATTTTTCGAACGAATGATGGAGGCCCGCGAGCAGGAACGGGTCGCCGAGGCGAAGTACCGCAGCCTTTTC
GAGAACGCGGCGGAGGGGATCTTCCGCAGGACCCCCGAGGGGAGGTACCTCGACGCGAACCCCGCCCTCGCGCACATGCT
TGGCTATGCCTCTCCCGCGGAGCTGGTCGCCTCCATCACCGACATCGGTACCGAGGTCTACGTGGACCCCGCCTCCTATG
CGGAGATGCAGAGGGTGCTGGCGGTCCACGGCAGGGCCGAAAGTTTCGAGACGCAGATCTACCGCAAGGACGGCAGTGTG
ATCTGGGTATCCCTGAGCCTGCGCGCAGTGCGGGACAGCGAGGGGAAGGTGCTCTTTTACGAGGGGATGTCCGAGGAGAT
CACCAAGCGTAAGATTGCCGAGGCCGCGCTGCGCGAGAGCGAGCAGAAGTACCGCCAGTTGAGCGAGGCGCTGGAGCGGC
GCGTGAAGCAGGCGGTCGACGAACTGCGCCAGAAGGACAAGATGCTGATCCTGCAGGGGCGGCAGGCGGTGATGGGGGAG
ATGCTGAGCAACATCGCCCACCAGTGGCGCCAGCCCCTGAACATGCTGGCCTTGCTGGTCCAGGACGTCCAGTTGACCCA
CAGGCAAACCGGGCTCAGCGAAGAGTTCATATGTGAGAACGTCAGAAGGAGCATGGAGATCATCCAGCAGATGTCCCAAA
CCATAGACGATTTCAGGTATTTCTACCGCCCGGACCGGGAAAAACTTGAGTTCACGGTGAGCGAGCCTTTGGATAAGGCG
CTGGCCCTGTTGAATGGGAGCTTAAGGATACACAGTATAGAGATCCAGGTCCTTAAAACCGGCGAACCTTCAATCAAGGG
ATATCTCGGAGAGTTCGTCCAGGTCCTGCTCAACATCCTGATCAACGCTCGCGACGCGCTCATCGCCAGCCGCGCCGCTT
CGCCGCTCATCACCGTCAGGCTCTACGAGGAAGGCGGGGAAACGGTGGTCAGGATCGCTGACAACGCCGGCGGCATCCCC
GAGGAGATCAAGGAGAAGATCTTCGAACCCTACTTCACCACCAAAGGGCCCGAGCAGGGAACCGGCATCGGGCTTTTCAT
GTGCAAGACCATCATCGAGAAGAGCATGAACGGCAGGCTCTGCGCCAGTAACAGCGGCGAGGGAGCCGAGTTCGTCATCA
CCGTCCCCAAAACTCCCTGA

Upstream 100 bases:

>100_bases
TTCTACTCATACGCCGAGATCGGACCGGTCTCCGGCTACAACTGCATCCACAATTTCACGTCCGTGCTGTTGGCCGTGTA
CTAGAGTGCCACGGGGTAAC

Downstream 100 bases:

>100_bases
TATCGCTCAATATGGCATCCGAGACCAGCTCCTTTGCCCCTGACTCGAACCAATCCCCAGGCATGGCGGAACTGTACTCC
TCTTGCAAGAAACGGTCGTC

Product: PAS/PAC domain-containing sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MKNGSPTDKQALEQQLTALRRENEELAQQVKRLIRAEGKLYEYQQVLDLQLNEYKGLYDLSRRLSGSFYIQGLFRETVQY
VVQQLEYERAILLRREETVTYRVLALDGYYDPSEKEQAAAITMKYGAPCLSPLLAGREHVTCTATSTEPGNGCRRRLLMD
EFLVYPLGHDEVPHALLVVGNTATNAPFHRRVQESDQALLSMGNLVGLVSSILDTHIFFERMMEAREQERVAEAKYRSLF
ENAAEGIFRRTPEGRYLDANPALAHMLGYASPAELVASITDIGTEVYVDPASYAEMQRVLAVHGRAESFETQIYRKDGSV
IWVSLSLRAVRDSEGKVLFYEGMSEEITKRKIAEAALRESEQKYRQLSEALERRVKQAVDELRQKDKMLILQGRQAVMGE
MLSNIAHQWRQPLNMLALLVQDVQLTHRQTGLSEEFICENVRRSMEIIQQMSQTIDDFRYFYRPDREKLEFTVSEPLDKA
LALLNGSLRIHSIEIQVLKTGEPSIKGYLGEFVQVLLNILINARDALIASRAASPLITVRLYEEGGETVVRIADNAGGIP
EEIKEKIFEPYFTTKGPEQGTGIGLFMCKTIIEKSMNGRLCASNSGEGAEFVITVPKTP

Sequences:

>Translated_619_residues
MKNGSPTDKQALEQQLTALRRENEELAQQVKRLIRAEGKLYEYQQVLDLQLNEYKGLYDLSRRLSGSFYIQGLFRETVQY
VVQQLEYERAILLRREETVTYRVLALDGYYDPSEKEQAAAITMKYGAPCLSPLLAGREHVTCTATSTEPGNGCRRRLLMD
EFLVYPLGHDEVPHALLVVGNTATNAPFHRRVQESDQALLSMGNLVGLVSSILDTHIFFERMMEAREQERVAEAKYRSLF
ENAAEGIFRRTPEGRYLDANPALAHMLGYASPAELVASITDIGTEVYVDPASYAEMQRVLAVHGRAESFETQIYRKDGSV
IWVSLSLRAVRDSEGKVLFYEGMSEEITKRKIAEAALRESEQKYRQLSEALERRVKQAVDELRQKDKMLILQGRQAVMGE
MLSNIAHQWRQPLNMLALLVQDVQLTHRQTGLSEEFICENVRRSMEIIQQMSQTIDDFRYFYRPDREKLEFTVSEPLDKA
LALLNGSLRIHSIEIQVLKTGEPSIKGYLGEFVQVLLNILINARDALIASRAASPLITVRLYEEGGETVVRIADNAGGIP
EEIKEKIFEPYFTTKGPEQGTGIGLFMCKTIIEKSMNGRLCASNSGEGAEFVITVPKTP
>Mature_619_residues
MKNGSPTDKQALEQQLTALRRENEELAQQVKRLIRAEGKLYEYQQVLDLQLNEYKGLYDLSRRLSGSFYIQGLFRETVQY
VVQQLEYERAILLRREETVTYRVLALDGYYDPSEKEQAAAITMKYGAPCLSPLLAGREHVTCTATSTEPGNGCRRRLLMD
EFLVYPLGHDEVPHALLVVGNTATNAPFHRRVQESDQALLSMGNLVGLVSSILDTHIFFERMMEAREQERVAEAKYRSLF
ENAAEGIFRRTPEGRYLDANPALAHMLGYASPAELVASITDIGTEVYVDPASYAEMQRVLAVHGRAESFETQIYRKDGSV
IWVSLSLRAVRDSEGKVLFYEGMSEEITKRKIAEAALRESEQKYRQLSEALERRVKQAVDELRQKDKMLILQGRQAVMGE
MLSNIAHQWRQPLNMLALLVQDVQLTHRQTGLSEEFICENVRRSMEIIQQMSQTIDDFRYFYRPDREKLEFTVSEPLDKA
LALLNGSLRIHSIEIQVLKTGEPSIKGYLGEFVQVLLNILINARDALIASRAASPLITVRLYEEGGETVVRIADNAGGIP
EEIKEKIFEPYFTTKGPEQGTGIGLFMCKTIIEKSMNGRLCASNSGEGAEFVITVPKTP

Specific function: Member of the two-component regulatory system nodV/nodW probably involved in the regulation of the transcription of genes involved in the nodulation process. NodV may function as a membrane-associated protein kinase that phosphorylates nodW in response to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=385, Percent_Identity=24.9350649350649, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=28.0632411067194, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786837, Length=109, Percent_Identity=31.1926605504587, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70082; Mature: 70082

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNGSPTDKQALEQQLTALRRENEELAQQVKRLIRAEGKLYEYQQVLDLQLNEYKGLYDL
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHH
SRRLSGSFYIQGLFRETVQYVVQQLEYERAILLRREETVTYRVLALDGYYDPSEKEQAAA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEEEECCCCCCCCCHHHE
ITMKYGAPCLSPLLAGREHVTCTATSTEPGNGCRRRLLMDEFLVYPLGHDEVPHALLVVG
EEEECCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
NTATNAPFHRRVQESDQALLSMGNLVGLVSSILDTHIFFERMMEAREQERVAEAKYRSLF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAAEGIFRRTPEGRYLDANPALAHMLGYASPAELVASITDIGTEVYVDPASYAEMQRVL
HHHHHHHHHCCCCCCEECCCHHHHHHHCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHH
AVHGRAESFETQIYRKDGSVIWVSLSLRAVRDSEGKVLFYEGMSEEITKRKIAEAALRES
HHHCCCHHHHHHHEECCCCEEEEEEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHH
EQKYRQLSEALERRVKQAVDELRQKDKMLILQGRQAVMGEMLSNIAHQWRQPLNMLALLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDVQLTHRQTGLSEEFICENVRRSMEIIQQMSQTIDDFRYFYRPDREKLEFTVSEPLDKA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHHHHHH
LALLNGSLRIHSIEIQVLKTGEPSIKGYLGEFVQVLLNILINARDALIASRAASPLITVR
HHHHCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LYEEGGETVVRIADNAGGIPEEIKEKIFEPYFTTKGPEQGTGIGLFMCKTIIEKSMNGRL
EEECCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
CASNSGEGAEFVITVPKTP
EECCCCCCCEEEEECCCCC
>Mature Secondary Structure
MKNGSPTDKQALEQQLTALRRENEELAQQVKRLIRAEGKLYEYQQVLDLQLNEYKGLYDL
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHH
SRRLSGSFYIQGLFRETVQYVVQQLEYERAILLRREETVTYRVLALDGYYDPSEKEQAAA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEEEECCCCCCCCCHHHE
ITMKYGAPCLSPLLAGREHVTCTATSTEPGNGCRRRLLMDEFLVYPLGHDEVPHALLVVG
EEEECCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
NTATNAPFHRRVQESDQALLSMGNLVGLVSSILDTHIFFERMMEAREQERVAEAKYRSLF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAAEGIFRRTPEGRYLDANPALAHMLGYASPAELVASITDIGTEVYVDPASYAEMQRVL
HHHHHHHHHCCCCCCEECCCHHHHHHHCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHH
AVHGRAESFETQIYRKDGSVIWVSLSLRAVRDSEGKVLFYEGMSEEITKRKIAEAALRES
HHHCCCHHHHHHHEECCCCEEEEEEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHH
EQKYRQLSEALERRVKQAVDELRQKDKMLILQGRQAVMGEMLSNIAHQWRQPLNMLALLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDVQLTHRQTGLSEEFICENVRRSMEIIQQMSQTIDDFRYFYRPDREKLEFTVSEPLDKA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHHHHHH
LALLNGSLRIHSIEIQVLKTGEPSIKGYLGEFVQVLLNILINARDALIASRAASPLITVR
HHHHCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LYEEGGETVVRIADNAGGIPEEIKEKIFEPYFTTKGPEQGTGIGLFMCKTIIEKSMNGRL
EEECCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
CASNSGEGAEFVITVPKTP
EECCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2320582; 11157954; 12597275 [H]