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The map label for this gene is 197120399

Identifier: 197120399

GI number: 197120399

Start: 4591157

End: 4592347

Strand: Direct

Name: 197120399

Synonym: Gbem_4040

Alternate gene names: NA

Gene position: 4591157-4592347 (Clockwise)

Preceding gene: 197120393

Following gene: 197120400

Centisome position: 99.48

GC content: 63.22

Gene sequence:

>1191_bases
ATGGGAACTTCTGCAGGCGTTGGCTTCAGCCTTCACAAAAACCCGGCTGACGCGGGCAAGGAAGCGGCTCTCCAGGCGAT
GGAGCGGGGCGGGATGGCCAAACCGGATTTCGTCTTCGTCTTCGCCACGGTGGGATACGACCAGGAGTTGCTGATTCGCT
CGGTGCGCGACACCACCGCCGGCGCCCCCTTGAGCGGCTGCTCAGGGGAGGGGGTGATCACGGCGGGCGCCGCCGCCGAG
ACCAACTTCGGGGTCTGCGTGCTGGCCATAGCCTCGGATGAGGTCAGCTTCGCCAACGCCTACGTGCAGGGGCTCGATGC
CGGATACGCCCGGGCCGGCGAGTTGCTGGCCGAGCAGGTCCGCCCGCTGCTCCATGCCGACGCCGTCGCCTGCTTTCTCT
TTGCCGACGGCCTTCTCTTCGACTTCGATCCCTTCCGGGACGCCTTCGAAAGGACCCTCGGGCACGGGAGGCCGCTCCCC
CTGTTCGGAGGGCTTGCCGCCAACAACCTCTCTACCCGGAAGACCTACCAGTACCATGACGACCAGGTAATTTCCGAAGG
GATCTGCTGCGTCGTCATGTCCGGCAATGCCAGGCTCGCCTGGGGGGTCAACCACGGCTGCGTGCCGGTGGGAACCCGGC
GCACCATCACCCGCTGCCACGGCAACATCATCTACGAGATCGACGGCATCCCTGCACTGGAGGCCTTGAAGGAGTACATC
GAAGACGGCTCCGGCAGCGACTGGAACAAGGTCACCCTCAACCTCTGCCTCGGCTTCAAGACCCCGGAGCACCTGAGGAA
GGAATACGGCGAGTACATCATCCGCTACATGATGGACAAAAACGACCAGGAGGGGTGGGTAAGCATCCAGTCGGATGTGA
CCCAGGGAAGCGCTCTTTGGATCATGAGGCGGGACAAGGAGCTGATGCGGGAAGGGCTGCAGGCCATCTCGCAGCATATC
AGGGAGCAGTTGGGAGAGAACCGGCCCAAGCTGGTGATGCAGTTCGAATGCATGGGGCGCGGGCGCGTGGTCTACCGCGA
GCAGGAGAAGATCGAGCTGCTCAAGTCCCTGCAGGACGACCTGGGGGCGGAACTACCCTGGATCGGATTCTACTCATACG
CCGAGATCGGACCGGTCTCCGGCTACAACTGCATCCACAATTTCACGTCCGTGCTGTTGGCCGTGTACTAG

Upstream 100 bases:

>100_bases
TCATAAAAAGCACATGCTATATTAAAATGAATTCATATTGTTATAATGTTCCCTGGCCCGGCCCCAGATAGCCGGGTAAT
CCCCAGAAAAGAGGTGCTAT

Downstream 100 bases:

>100_bases
AGTGCCACGGGGTAACATGAAAAACGGGAGTCCCACCGACAAACAGGCCCTGGAGCAGCAGTTGACTGCCCTGCGCAGGG
AAAACGAGGAGCTGGCCCAA

Product: FIST domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MGTSAGVGFSLHKNPADAGKEAALQAMERGGMAKPDFVFVFATVGYDQELLIRSVRDTTAGAPLSGCSGEGVITAGAAAE
TNFGVCVLAIASDEVSFANAYVQGLDAGYARAGELLAEQVRPLLHADAVACFLFADGLLFDFDPFRDAFERTLGHGRPLP
LFGGLAANNLSTRKTYQYHDDQVISEGICCVVMSGNARLAWGVNHGCVPVGTRRTITRCHGNIIYEIDGIPALEALKEYI
EDGSGSDWNKVTLNLCLGFKTPEHLRKEYGEYIIRYMMDKNDQEGWVSIQSDVTQGSALWIMRRDKELMREGLQAISQHI
REQLGENRPKLVMQFECMGRGRVVYREQEKIELLKSLQDDLGAELPWIGFYSYAEIGPVSGYNCIHNFTSVLLAVY

Sequences:

>Translated_396_residues
MGTSAGVGFSLHKNPADAGKEAALQAMERGGMAKPDFVFVFATVGYDQELLIRSVRDTTAGAPLSGCSGEGVITAGAAAE
TNFGVCVLAIASDEVSFANAYVQGLDAGYARAGELLAEQVRPLLHADAVACFLFADGLLFDFDPFRDAFERTLGHGRPLP
LFGGLAANNLSTRKTYQYHDDQVISEGICCVVMSGNARLAWGVNHGCVPVGTRRTITRCHGNIIYEIDGIPALEALKEYI
EDGSGSDWNKVTLNLCLGFKTPEHLRKEYGEYIIRYMMDKNDQEGWVSIQSDVTQGSALWIMRRDKELMREGLQAISQHI
REQLGENRPKLVMQFECMGRGRVVYREQEKIELLKSLQDDLGAELPWIGFYSYAEIGPVSGYNCIHNFTSVLLAVY
>Mature_395_residues
GTSAGVGFSLHKNPADAGKEAALQAMERGGMAKPDFVFVFATVGYDQELLIRSVRDTTAGAPLSGCSGEGVITAGAAAET
NFGVCVLAIASDEVSFANAYVQGLDAGYARAGELLAEQVRPLLHADAVACFLFADGLLFDFDPFRDAFERTLGHGRPLPL
FGGLAANNLSTRKTYQYHDDQVISEGICCVVMSGNARLAWGVNHGCVPVGTRRTITRCHGNIIYEIDGIPALEALKEYIE
DGSGSDWNKVTLNLCLGFKTPEHLRKEYGEYIIRYMMDKNDQEGWVSIQSDVTQGSALWIMRRDKELMREGLQAISQHIR
EQLGENRPKLVMQFECMGRGRVVYREQEKIELLKSLQDDLGAELPWIGFYSYAEIGPVSGYNCIHNFTSVLLAVY

Specific function: Unknown

COG id: COG3287

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv0874c [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019494
- InterPro:   IPR013702
- InterPro:   IPR016741 [H]

Pfam domain/function: PF08495 FIST; PF10442 FIST_C [H]

EC number: NA

Molecular weight: Translated: 43474; Mature: 43343

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTSAGVGFSLHKNPADAGKEAALQAMERGGMAKPDFVFVFATVGYDQELLIRSVRDTTA
CCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCC
GAPLSGCSGEGVITAGAAAETNFGVCVLAIASDEVSFANAYVQGLDAGYARAGELLAEQV
CCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHH
RPLLHADAVACFLFADGLLFDFDPFRDAFERTLGHGRPLPLFGGLAANNLSTRKTYQYHD
HHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCEEECC
DQVISEGICCVVMSGNARLAWGVNHGCVPVGTRRTITRCHGNIIYEIDGIPALEALKEYI
HHHHCCCEEEEEEECCEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCCHHHHHHHHH
EDGSGSDWNKVTLNLCLGFKTPEHLRKEYGEYIIRYMMDKNDQEGWVSIQSDVTQGSALW
HCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEE
IMRRDKELMREGLQAISQHIREQLGENRPKLVMQFECMGRGRVVYREQEKIELLKSLQDD
EEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHH
LGAELPWIGFYSYAEIGPVSGYNCIHNFTSVLLAVY
HCCCCCCEEEECHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GTSAGVGFSLHKNPADAGKEAALQAMERGGMAKPDFVFVFATVGYDQELLIRSVRDTTA
CCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCC
GAPLSGCSGEGVITAGAAAETNFGVCVLAIASDEVSFANAYVQGLDAGYARAGELLAEQV
CCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHH
RPLLHADAVACFLFADGLLFDFDPFRDAFERTLGHGRPLPLFGGLAANNLSTRKTYQYHD
HHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCEEECC
DQVISEGICCVVMSGNARLAWGVNHGCVPVGTRRTITRCHGNIIYEIDGIPALEALKEYI
HHHHCCCEEEEEEECCEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCCHHHHHHHHH
EDGSGSDWNKVTLNLCLGFKTPEHLRKEYGEYIIRYMMDKNDQEGWVSIQSDVTQGSALW
HCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEE
IMRRDKELMREGLQAISQHIREQLGENRPKLVMQFECMGRGRVVYREQEKIELLKSLQDD
EEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHH
LGAELPWIGFYSYAEIGPVSGYNCIHNFTSVLLAVY
HCCCCCCEEEECHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]