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The map label for this gene is gctA [H]

Identifier: 197119198

GI number: 197119198

Start: 3250903

End: 3251865

Strand: Reverse

Name: gctA [H]

Synonym: Gbem_2825

Alternate gene names: 197119198

Gene position: 3251865-3250903 (Counterclockwise)

Preceding gene: 197119199

Following gene: 197119197

Centisome position: 70.46

GC content: 63.97

Gene sequence:

>963_bases
ATGACTGGCAAGCGCATCACCTTACAGCAGGCTGCGGAGATCATCAAGGACGGCTCCAGCCTCACCTTTTCCGGCTTCAC
CATCTGGCGCCGCCCCTTCGCGCTGGTGTTCGAACTGATCCGCCAGGGGCGCAAGGGGCTGCACCTGATCGAGGTCAACG
GCGGCCCGCAGACCGAGTTCCTCGTCGGTGCCGGCTGCGTCGACATCTGGGAGTCGTGCTGGGTGGGCCATGAGCTTTAC
GGCAAGTACGGCGCCAACCTCTCCAGGAAGGTCGGCAACAAGGAGATCATCGTCGAGGACTACAGCCACGCGGAGATGTT
GTTCCGCTTCGCCGCCGCGGCTTCCGGCGCCCCCTACGCGGCGACCCAGACCTCGCTCGGGACCGACCTGCACAACCCCG
AGTACGACATGCTGGGACGAGCGGGCCTCAGGGACGGCAAAAGGATTCCCAAACACAAGTACATCTTCACCGAGGACCCC
TTCTACGGCGCCGGAGAGCAGGTGCTGGTCCCCGCGGCGAAGGTCGACGTGGCGGTCATGTGCGTGCAACAGGTGGGGGA
GGAGGGGACGGTGCGGGTGAACGGCCAGTTCTACTCCGACCCGGAAGCGGCCCGGGCCGCCGACATCACCATTGTCATGG
CGGAGGAGATTGTCCCCGAGGAGTACCTGCGCCGGGAGAGCGACCGCAACACCATAGCGAGCTTCGAGGTCGATTACATC
GTCGAATGCCCCTTCGGCGCACACCCCACGGGGATGTTCGGGCGCTACGACGTGGACGGAGCCTTCCTCAAGGACTTCTA
CGGCAGGACCAGGACCCAGGAAGGGTTCGACGACTTTGCCAAGGAGTGGATCCACGGTCAGGACCACCATAGCTACCTGG
AGAAACTGGGCTGGCCGCGCATGCTGAACCTCAAGGCCAATACCGCGCTCAACTACAGCACCGGCGTGAAAAGGGGGCAA
TGA

Upstream 100 bases:

>100_bases
TGATCATAGCCAGGGAGATATTGCGCAACTTCAATTGAAGCGTCCGACAGGTCAGACAGGTCAGACAGGTCCGACTGATT
GAGAAAACAGGAGGGTGTCT

Downstream 100 bases:

>100_bases
CATGGAAAGCAATTACGCAACTCCCGAAGAATACGGCCTCCCCGATCTTCTCTGCTGCGCCGCCTCGCGCGAGGTAAAGG
ACAACGAAATCGTCTTCGCC

Product: coenzyme A transferase subunit alpha

Products: NA

Alternate protein names: GCT large subunit [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTGKRITLQQAAEIIKDGSSLTFSGFTIWRRPFALVFELIRQGRKGLHLIEVNGGPQTEFLVGAGCVDIWESCWVGHELY
GKYGANLSRKVGNKEIIVEDYSHAEMLFRFAAAASGAPYAATQTSLGTDLHNPEYDMLGRAGLRDGKRIPKHKYIFTEDP
FYGAGEQVLVPAAKVDVAVMCVQQVGEEGTVRVNGQFYSDPEAARAADITIVMAEEIVPEEYLRRESDRNTIASFEVDYI
VECPFGAHPTGMFGRYDVDGAFLKDFYGRTRTQEGFDDFAKEWIHGQDHHSYLEKLGWPRMLNLKANTALNYSTGVKRGQ

Sequences:

>Translated_320_residues
MTGKRITLQQAAEIIKDGSSLTFSGFTIWRRPFALVFELIRQGRKGLHLIEVNGGPQTEFLVGAGCVDIWESCWVGHELY
GKYGANLSRKVGNKEIIVEDYSHAEMLFRFAAAASGAPYAATQTSLGTDLHNPEYDMLGRAGLRDGKRIPKHKYIFTEDP
FYGAGEQVLVPAAKVDVAVMCVQQVGEEGTVRVNGQFYSDPEAARAADITIVMAEEIVPEEYLRRESDRNTIASFEVDYI
VECPFGAHPTGMFGRYDVDGAFLKDFYGRTRTQEGFDDFAKEWIHGQDHHSYLEKLGWPRMLNLKANTALNYSTGVKRGQ
>Mature_319_residues
TGKRITLQQAAEIIKDGSSLTFSGFTIWRRPFALVFELIRQGRKGLHLIEVNGGPQTEFLVGAGCVDIWESCWVGHELYG
KYGANLSRKVGNKEIIVEDYSHAEMLFRFAAAASGAPYAATQTSLGTDLHNPEYDMLGRAGLRDGKRIPKHKYIFTEDPF
YGAGEQVLVPAAKVDVAVMCVQQVGEEGTVRVNGQFYSDPEAARAADITIVMAEEIVPEEYLRRESDRNTIASFEVDYIV
ECPFGAHPTGMFGRYDVDGAFLKDFYGRTRTQEGFDDFAKEWIHGQDHHSYLEKLGWPRMLNLKANTALNYSTGVKRGQ

Specific function: Catalyzes the transfer of the CoA moiety from acetyl-CoA to (R)-2-hydroxyglutarate and related compounds like glutaconate [H]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004165 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.12 [H]

Molecular weight: Translated: 35766; Mature: 35635

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGKRITLQQAAEIIKDGSSLTFSGFTIWRRPFALVFELIRQGRKGLHLIEVNGGPQTEF
CCCCEEEHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEE
LVGAGCVDIWESCWVGHELYGKYGANLSRKVGNKEIIVEDYSHAEMLFRFAAAASGAPYA
EEECCHHHHHHHHCCCHHHHHHHCCCHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCC
ATQTSLGTDLHNPEYDMLGRAGLRDGKRIPKHKYIFTEDPFYGAGEQVLVPAAKVDVAVM
CCHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEECHHHHHHHHH
CVQQVGEEGTVRVNGQFYSDPEAARAADITIVMAEEIVPEEYLRRESDRNTIASFEVDYI
HHHHHCCCCEEEECCEEECCCCHHHHCEEEEEEHHHHCCHHHHHHCCCCCEEEEEEEEEE
VECPFGAHPTGMFGRYDVDGAFLKDFYGRTRTQEGFDDFAKEWIHGQDHHSYLEKLGWPR
EECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCE
MLNLKANTALNYSTGVKRGQ
EEEEECCCEECCCCCCCCCC
>Mature Secondary Structure 
TGKRITLQQAAEIIKDGSSLTFSGFTIWRRPFALVFELIRQGRKGLHLIEVNGGPQTEF
CCCEEEHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEE
LVGAGCVDIWESCWVGHELYGKYGANLSRKVGNKEIIVEDYSHAEMLFRFAAAASGAPYA
EEECCHHHHHHHHCCCHHHHHHHCCCHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCC
ATQTSLGTDLHNPEYDMLGRAGLRDGKRIPKHKYIFTEDPFYGAGEQVLVPAAKVDVAVM
CCHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEECHHHHHHHHH
CVQQVGEEGTVRVNGQFYSDPEAARAADITIVMAEEIVPEEYLRRESDRNTIASFEVDYI
HHHHHCCCCEEEECCEEECCCCHHHHCEEEEEEHHHHCCHHHHHHCCCCCEEEEEEEEEE
VECPFGAHPTGMFGRYDVDGAFLKDFYGRTRTQEGFDDFAKEWIHGQDHHSYLEKLGWPR
EECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCE
MLNLKANTALNYSTGVKRGQ
EEEEECCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957258; 9083111 [H]