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The map label for this gene is frr

Identifier: 197119126

GI number: 197119126

Start: 3183156

End: 3183713

Strand: Reverse

Name: frr

Synonym: Gbem_2753

Alternate gene names: 197119126

Gene position: 3183713-3183156 (Counterclockwise)

Preceding gene: 197119127

Following gene: 197119125

Centisome position: 68.98

GC content: 57.53

Gene sequence:

>558_bases
ATGGTCAAGGATGTCATCTCCAGCATGAACGTCCATATGGACAAATCCATAGAATCGCTCAGGAAAGAGTACCAGAAGGT
GCGCACCGGCCGTGCCAGCACCTCTTTGTTGGACGATATCAAGGTCGACAGCTACGGCACCCTTTCGCCGCTGAACCAGG
TAGCGACCCTCGCCATCCCCGAGGCGCGCACCATCACCATTTCGCCCTGGGACTCGAAGATGATCGCGCCCATCGAGAAG
GCCATCATGAACTCCAACCTGGGGCTCAACCCGGCCAACGACGGCAAGATGATCCGCCTGACTCTTCCTCCCCTCACCGA
GGAGAGGCGCAAGGATATCGTGAAGCAGCTGAAGCGTGACGCCGAGGACGCCAAGGTCGCTCTGAGAAACATCCGTCGCG
ACGCCATCGACCAGTTGAAGAAGCTGGAGAAGGACAAGTCCATTTCCGAGGACGAGCAAAAGCGCGCCGAGAAGGAAGTC
CAGGACTTCACCAACAGCCACGTCGCCAAGGTGGACGAGGTGCTGCTCCACAAGGAAAAAGAGGTTATGGAGGTCTAA

Upstream 100 bases:

>100_bases
AGCCTCCCGATCATCGTCTTCGACGTGACCACCGACGGCAACGTCGTCCGGGTGGTCAACGGTGAACCGATCGGTACCCT
CGTCAAGGAAGGAGAATAGC

Downstream 100 bases:

>100_bases
CGGCCTGTGCGGCAGGGGGGAGCACTCCCCCCTGCTGACCGACCGGCCCCTCTCCATTTGCGCAAACCCCCGACCCGCCG
GGGATTTTTTGTTTTCAGGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MVKDVISSMNVHMDKSIESLRKEYQKVRTGRASTSLLDDIKVDSYGTLSPLNQVATLAIPEARTITISPWDSKMIAPIEK
AIMNSNLGLNPANDGKMIRLTLPPLTEERRKDIVKQLKRDAEDAKVALRNIRRDAIDQLKKLEKDKSISEDEQKRAEKEV
QDFTNSHVAKVDEVLLHKEKEVMEV

Sequences:

>Translated_185_residues
MVKDVISSMNVHMDKSIESLRKEYQKVRTGRASTSLLDDIKVDSYGTLSPLNQVATLAIPEARTITISPWDSKMIAPIEK
AIMNSNLGLNPANDGKMIRLTLPPLTEERRKDIVKQLKRDAEDAKVALRNIRRDAIDQLKKLEKDKSISEDEQKRAEKEV
QDFTNSHVAKVDEVLLHKEKEVMEV
>Mature_185_residues
MVKDVISSMNVHMDKSIESLRKEYQKVRTGRASTSLLDDIKVDSYGTLSPLNQVATLAIPEARTITISPWDSKMIAPIEK
AIMNSNLGLNPANDGKMIRLTLPPLTEERRKDIVKQLKRDAEDAKVALRNIRRDAIDQLKKLEKDKSISEDEQKRAEKEV
QDFTNSHVAKVDEVLLHKEKEVMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=187, Percent_Identity=32.0855614973262, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI291042689, Length=149, Percent_Identity=32.8859060402685, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=48.1081081081081, Blast_Score=181, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24661488, Length=177, Percent_Identity=23.728813559322, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_GEOBB (B5EHV8)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002139553.1
- ProteinModelPortal:   B5EHV8
- SMR:   B5EHV8
- GeneID:   6782751
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_2753
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21019; Mature: 21019

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKDVISSMNVHMDKSIESLRKEYQKVRTGRASTSLLDDIKVDSYGTLSPLNQVATLAIP
CHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
EARTITISPWDSKMIAPIEKAIMNSNLGLNPANDGKMIRLTLPPLTEERRKDIVKQLKRD
CCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
AEDAKVALRNIRRDAIDQLKKLEKDKSISEDEQKRAEKEVQDFTNSHVAKVDEVLLHKEK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVMEV
HHHCC
>Mature Secondary Structure
MVKDVISSMNVHMDKSIESLRKEYQKVRTGRASTSLLDDIKVDSYGTLSPLNQVATLAIP
CHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
EARTITISPWDSKMIAPIEKAIMNSNLGLNPANDGKMIRLTLPPLTEERRKDIVKQLKRD
CCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
AEDAKVALRNIRRDAIDQLKKLEKDKSISEDEQKRAEKEVQDFTNSHVAKVDEVLLHKEK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA