Click here to switch to the map view.

The map label for this gene is cobO-1 [H]

Identifier: 197119067

GI number: 197119067

Start: 3114014

End: 3114544

Strand: Reverse

Name: cobO-1 [H]

Synonym: Gbem_2692

Alternate gene names: 197119067

Gene position: 3114544-3114014 (Counterclockwise)

Preceding gene: 197119068

Following gene: 197119066

Centisome position: 67.49

GC content: 62.15

Gene sequence:

>531_bases
GTGAAACTGGAACAAGGTCTTATTCAGGTGTATACCGGCAACGGCAAGGGTAAGACCACCGCGTCTTTGGGACTTGCGCT
GCGCGCTACGGGGCGTGAGCTTAAGGTCTGCATGATCCAGTTCATGAAGGGCGGGGGGCCTTACGGCGAGCAGATGGCCG
CCGAGCGCCTGGCGCCGTTTCTCACCATCATCCAGACCGGGCGCCCGGGCTGGGTCAGAAAGGGTAACCCCCACGAAGAG
GACAAACAGCTGGCGGCCGAGGCGCTGGAATTGGCGGCGAAGACTGTCCAGAGCGGCGAGTACGACCTGGTGATACTCGA
CGAGATCAACGGTGCGGTCTCCATGGGGCTCGTCCCCGTCGACGGGGTACTCGATCTCATGCGCGGCAAGCCGCATCATG
TCGAACTGGTGCTGACCGGCAGAAATGCCCACGAAAGCGTGATCGAGGCCGCCGACCTGGTAACCGAGATGCGCGAGGTC
AAGCACTACTACAAGGCCGGAGTGCCGGCGCGGATCGGCATCGAGAAATAG

Upstream 100 bases:

>100_bases
ACCCCTGCTGTAGGGGGCGCTCGCGGCATCGATGCCGTTGCCGTAAACTGCTTCATTTCTGTCAGTCGAATCGAATTGCC
GGTTCTGTCAAGGTGTGATT

Downstream 100 bases:

>100_bases
TGACGCTTTAAAAGCTTGGTAGCTTTATATTTCAATACTGATAAATTCGGAGGTATGCCATGGCTGAAAGAAGAATACGT
GTACTGGTAGGTAAGCCGGG

Product: cob(I)yrinate a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MKLEQGLIQVYTGNGKGKTTASLGLALRATGRELKVCMIQFMKGGGPYGEQMAAERLAPFLTIIQTGRPGWVRKGNPHEE
DKQLAAEALELAAKTVQSGEYDLVILDEINGAVSMGLVPVDGVLDLMRGKPHHVELVLTGRNAHESVIEAADLVTEMREV
KHYYKAGVPARIGIEK

Sequences:

>Translated_176_residues
MKLEQGLIQVYTGNGKGKTTASLGLALRATGRELKVCMIQFMKGGGPYGEQMAAERLAPFLTIIQTGRPGWVRKGNPHEE
DKQLAAEALELAAKTVQSGEYDLVILDEINGAVSMGLVPVDGVLDLMRGKPHHVELVLTGRNAHESVIEAADLVTEMREV
KHYYKAGVPARIGIEK
>Mature_176_residues
MKLEQGLIQVYTGNGKGKTTASLGLALRATGRELKVCMIQFMKGGGPYGEQMAAERLAPFLTIIQTGRPGWVRKGNPHEE
DKQLAAEALELAAKTVQSGEYDLVILDEINGAVSMGLVPVDGVLDLMRGKPHHVELVLTGRNAHESVIEAADLVTEMREV
KHYYKAGVPARIGIEK

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=172, Percent_Identity=38.3720930232558, Blast_Score=123, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19075; Mature: 19075

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEQGLIQVYTGNGKGKTTASLGLALRATGRELKVCMIQFMKGGGPYGEQMAAERLAPF
CCCCCCEEEEEECCCCCCCHHHHHEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LTIIQTGRPGWVRKGNPHEEDKQLAAEALELAAKTVQSGEYDLVILDEINGAVSMGLVPV
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCH
DGVLDLMRGKPHHVELVLTGRNAHESVIEAADLVTEMREVKHYYKAGVPARIGIEK
HHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKLEQGLIQVYTGNGKGKTTASLGLALRATGRELKVCMIQFMKGGGPYGEQMAAERLAPF
CCCCCCEEEEEECCCCCCCHHHHHEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LTIIQTGRPGWVRKGNPHEEDKQLAAEALELAAKTVQSGEYDLVILDEINGAVSMGLVPV
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCH
DGVLDLMRGKPHHVELVLTGRNAHESVIEAADLVTEMREVKHYYKAGVPARIGIEK
HHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]