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The map label for this gene is argK [C]

Identifier: 197119065

GI number: 197119065

Start: 3112458

End: 3113402

Strand: Reverse

Name: argK [C]

Synonym: Gbem_2690

Alternate gene names: 197119065

Gene position: 3113402-3112458 (Counterclockwise)

Preceding gene: 197119066

Following gene: 197119064

Centisome position: 67.46

GC content: 63.28

Gene sequence:

>945_bases
ATGAGCCTTGCCGAACGTGTGCTGGATGGCGAGATACGCGCCGCGGCGCGCCTGATGCGGGATATCGACGACCGTTTCAA
AAGCGCCGTCGACGAACTGAAGATCCTCTACCCCCATACCGGAAAAGCCTATATCATCGGCATCACCGGCCCGCCTGGCG
CCGGCAAGTCGACCCTCGTCGACCAGGTAGTCGCGGCCTACCGCAAGAAGGACCTCCTGGTGGGTGTGGTGGCGATCGAC
CCGACCAGCCCTTTTTCCGGCGGCGCCATCCTGGGTGACCGCATCCGCATGAACCGCCATGCCGACGACCCCGGCGTCTT
CATCAGGAGTCTCGCCACACGCGGCGCCCTGGGAGGGCTTTCGCGCTCTACCATGGACGTGCTCAACGTGATGGACGCGA
TGGGGCTCGACGTCATCGTGGTGGAAACGGTCGGGGTAGGGCAGGACGAGGTCGACATCGTCAGCACCGCGCACACCACC
GTGGTGGTCATGGTCCCGGGTCTGGGAGACGATATCCAGGCGATCAAGGCCGGCATCCTCGAAATCGGGGACGTCTTCGT
GGTCAACAAGGCGGACCGGGACGGCGCCGAGCGGACTGAGCGCGAACTGACCGCGATGCTCGAGATGAAGCACCCCGAGC
CCGGCGACTGGATGCCGCACGTGATCAAGACCGAGGCGGCCAAAGGGCTCGGCATCGACCAACTGGTGGATGAATTCGAG
GCGCACCACAGCTACCTCAAGGAGTCGGGCGCGCTGCAGCGCCTGATCCAGGAACGAAATGCCAAGATCTTCGCGGACAC
GCTGCGCGAGGAACTCTTCGAGTCAGTCTTCAGCGGCATAAAGGAAAGCGGGAAGTACCAGCAGATACTCGACGGCATGC
GCGACAGGAGCACCGATCCCTACAGCGCTGTGGAAGAGGTCATGGCTGCGCGCTCTTTTTCTTGA

Upstream 100 bases:

>100_bases
CACAGGCAGTTCGCGGCGCACCCGCGTAGAAGCCTGGAGAGACCCTGCGGCAACGTGTGGCAAGGCCTCTCCGATCATAT
ATGAATTCTGGAGTTGAAAC

Downstream 100 bases:

>100_bases
CCCTGGGACCTAAAGATGTTAATTAGAAGGCGAAATGGGGCGTAGGCCCCATTAGTCGTTTCTGGTCGGGAGTTGTCGAG
ATGTTTCGTAAGATACTGTT

Product: protein kinase, ArgK family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSLAERVLDGEIRAAARLMRDIDDRFKSAVDELKILYPHTGKAYIIGITGPPGAGKSTLVDQVVAAYRKKDLLVGVVAID
PTSPFSGGAILGDRIRMNRHADDPGVFIRSLATRGALGGLSRSTMDVLNVMDAMGLDVIVVETVGVGQDEVDIVSTAHTT
VVVMVPGLGDDIQAIKAGILEIGDVFVVNKADRDGAERTERELTAMLEMKHPEPGDWMPHVIKTEAAKGLGIDQLVDEFE
AHHSYLKESGALQRLIQERNAKIFADTLREELFESVFSGIKESGKYQQILDGMRDRSTDPYSAVEEVMAARSFS

Sequences:

>Translated_314_residues
MSLAERVLDGEIRAAARLMRDIDDRFKSAVDELKILYPHTGKAYIIGITGPPGAGKSTLVDQVVAAYRKKDLLVGVVAID
PTSPFSGGAILGDRIRMNRHADDPGVFIRSLATRGALGGLSRSTMDVLNVMDAMGLDVIVVETVGVGQDEVDIVSTAHTT
VVVMVPGLGDDIQAIKAGILEIGDVFVVNKADRDGAERTERELTAMLEMKHPEPGDWMPHVIKTEAAKGLGIDQLVDEFE
AHHSYLKESGALQRLIQERNAKIFADTLREELFESVFSGIKESGKYQQILDGMRDRSTDPYSAVEEVMAARSFS
>Mature_313_residues
SLAERVLDGEIRAAARLMRDIDDRFKSAVDELKILYPHTGKAYIIGITGPPGAGKSTLVDQVVAAYRKKDLLVGVVAIDP
TSPFSGGAILGDRIRMNRHADDPGVFIRSLATRGALGGLSRSTMDVLNVMDAMGLDVIVVETVGVGQDEVDIVSTAHTTV
VVMVPGLGDDIQAIKAGILEIGDVFVVNKADRDGAERTERELTAMLEMKHPEPGDWMPHVIKTEAAKGLGIDQLVDEFEA
HHSYLKESGALQRLIQERNAKIFADTLREELFESVFSGIKESGKYQQILDGMRDRSTDPYSAVEEVMAARSFS

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=235, Percent_Identity=33.6170212765957, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1789285, Length=319, Percent_Identity=31.3479623824451, Blast_Score=166, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71994275, Length=259, Percent_Identity=30.8880308880309, Blast_Score=140, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71994271, Length=259, Percent_Identity=30.8880308880309, Blast_Score=140, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34134; Mature: 34003

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAERVLDGEIRAAARLMRDIDDRFKSAVDELKILYPHTGKAYIIGITGPPGAGKSTLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCHHHHH
DQVVAAYRKKDLLVGVVAIDPTSPFSGGAILGDRIRMNRHADDPGVFIRSLATRGALGGL
HHHHHHHHHCCEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
SRSTMDVLNVMDAMGLDVIVVETVGVGQDEVDIVSTAHTTVVVMVPGLGDDIQAIKAGIL
CHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHEEECCEEEEEEECCCCCHHHHHHHHHH
EIGDVFVVNKADRDGAERTERELTAMLEMKHPEPGDWMPHVIKTEAAKGLGIDQLVDEFE
HHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
AHHSYLKESGALQRLIQERNAKIFADTLREELFESVFSGIKESGKYQQILDGMRDRSTDP
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
YSAVEEVMAARSFS
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SLAERVLDGEIRAAARLMRDIDDRFKSAVDELKILYPHTGKAYIIGITGPPGAGKSTLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCHHHHH
DQVVAAYRKKDLLVGVVAIDPTSPFSGGAILGDRIRMNRHADDPGVFIRSLATRGALGGL
HHHHHHHHHCCEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
SRSTMDVLNVMDAMGLDVIVVETVGVGQDEVDIVSTAHTTVVVMVPGLGDDIQAIKAGIL
CHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHEEECCEEEEEEECCCCCHHHHHHHHHH
EIGDVFVVNKADRDGAERTERELTAMLEMKHPEPGDWMPHVIKTEAAKGLGIDQLVDEFE
HHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
AHHSYLKESGALQRLIQERNAKIFADTLREELFESVFSGIKESGKYQQILDGMRDRSTDP
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
YSAVEEVMAARSFS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]