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The map label for this gene is 197119022

Identifier: 197119022

GI number: 197119022

Start: 3062034

End: 3063752

Strand: Reverse

Name: 197119022

Synonym: Gbem_2645

Alternate gene names: NA

Gene position: 3063752-3062034 (Counterclockwise)

Preceding gene: 197119028

Following gene: 197119021

Centisome position: 66.38

GC content: 61.61

Gene sequence:

>1719_bases
ATGACCAAGAAGTGTCTAGCGCTCCTTTCCCTCACTTTGTTAATTAATGCCTGCGCCAGCGAGCACGCCGCCGGCACGAT
CCCTTCGGCCGGACTCGAGGCTGTTGCGGCCCCGTCGGCCGGTCCCGGAGAGGGACGCACCATGTACCTCTTCGCCTTGG
CGCGTCTGCGTGCCACCGAGGGGGATCAGGATGCGGCGCTCGTGCTTTTGCGCCAGGCGATGGAATCCGACCCGGCGGCA
GCCTACCTGCACACGGCGGCGGCCCAGATCCTCTTGCAGCAGAATAAACCCGAGGAGGCGCTGGTCGAAAGCCAGACCGC
CATCAATACCGACCCCGCTTTCCTGCAGGCGCAGCTTCTTTCAGGGAACATCCTGATGACCATGCAGCGCGAGAAGGAGG
CCATCCCCTATTACAAGAAGGTGATGGAACTCGACCCGACGAAAGAAGAGGTCTACCTCCACGTCGCCATCTATTACCTT
AAGAGTTTCGAGTACGAGCAGGCGGTCGACACCCTGAAGGCGTTGGTCAAGGCTTCGCCCGATTCGGCGCTCGGCTACTA
CTACCTTGCCAAGACCTACGAGCAGATGCGTCTGCCGCGCGAAGCGCTCGGCTACTACAAGAAGGCCCTCGATTTGAAGC
CGGACTTCGAGCAGGCGCTGATAGAGATGGGGATCTCGCAGGAGACCCAGGGGCTCATCCCCGACGCCATCGAGAGCTAC
AAGGGGCTTCTCGATATCAACCCTGCCAACGCCAACGTCGTGCAGCATCTGGCGCAGCTCTACATCCAGCAGAAGCGGCT
TAGCGAGGCGCTCGCCCTGTTGCAGGAAAAGGGGGGGAAGACCCTCGAGAACTCCCGCAAGATCGGGCTTTTGTTCCTGG
AGCTGGAGCGCTACGACGATGCGGTGAAGACCTTCCAGGAGATCCTCGAGGTAGAGCCTGCCTCCCAGCAGGTCCGCTTT
TACCTCGCCACCGCCTACGAAGAGAAGGATGCTGCCGACCTGGCCATCGCCGAATTCCTGAAGGTCCCCAAGGAGTCTCC
CTACTATCCCGATGCAGTCGGCCACCTGGCCTACCTGTACAAGGAGAAGGGGACCCCGGAGAAAGGGATCGCCCTCCTGA
AGGAAGAGGTTAAGGATCAGCCTTCGAGGGTCGAGCCGTACCTGCATCTGGCCGGCCTCTACGAGTCGATGGAGCGCTAC
CGGGAAGGGGTCGACACGCTGAATTCCATGGACGACAAGCTCCAGAACGACCCCCGCGTATTGTTCCGCCTCGGCATCCT
GTACGACAAACTCGGGCAGAAAGAGCAGTCGGTCGCCATGATGAAGCGGGTTATCGCCGCGACCCCGGACGACGCCAACG
CGCTCAACTACCTGGGGTACACCTATGCGGAGATGGGGGTGAACCTCGAGGAGGCGCTTTCCTACCTGAAGAAGGCGGTC
GAGCTGAAGCCGGACGACGGCTTCATCATGGACAGCCTCGGCTGGACCTACTTCAAGCTCAAGCGCTACAACGAGGCGGT
CGCCCAACTGGAGCGGGCAGCGGAGCTCTCCGACGAGGACGCCACGGTGCTCGGACATCTCGCCGACGCCTACTGCGCCG
CCCGTTCCTATAAGAAGGCGCTCCCGCTGTACCGGAAGCTGCAGAAGCTGGAGCCCGAGCAGAACGCCGAGCTCGCCGAG
AAGATCAGGCACTGCCGCCAGGAGAGCGGGGAAAAATGA

Upstream 100 bases:

>100_bases
TTTCGTGTAATTAGCCGCGCCATCCCTAGGATACTGTATCCCACAGGGTGCCGCGTTTTTTCGATTTTTGCCACGGAAAT
CTACCGACCACAGGTACCTC

Downstream 100 bases:

>100_bases
CCTTTTCCCGCTGTCTCCCCCTCCTTCTAGCCCTCCTTGTCTTCGCCGGTTGCGCCAAGGGTGCGCCTGAGGACAAGGCG
CGCGCGCAGGGCGGGGCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MTKKCLALLSLTLLINACASEHAAGTIPSAGLEAVAAPSAGPGEGRTMYLFALARLRATEGDQDAALVLLRQAMESDPAA
AYLHTAAAQILLQQNKPEEALVESQTAINTDPAFLQAQLLSGNILMTMQREKEAIPYYKKVMELDPTKEEVYLHVAIYYL
KSFEYEQAVDTLKALVKASPDSALGYYYLAKTYEQMRLPREALGYYKKALDLKPDFEQALIEMGISQETQGLIPDAIESY
KGLLDINPANANVVQHLAQLYIQQKRLSEALALLQEKGGKTLENSRKIGLLFLELERYDDAVKTFQEILEVEPASQQVRF
YLATAYEEKDAADLAIAEFLKVPKESPYYPDAVGHLAYLYKEKGTPEKGIALLKEEVKDQPSRVEPYLHLAGLYESMERY
REGVDTLNSMDDKLQNDPRVLFRLGILYDKLGQKEQSVAMMKRVIAATPDDANALNYLGYTYAEMGVNLEEALSYLKKAV
ELKPDDGFIMDSLGWTYFKLKRYNEAVAQLERAAELSDEDATVLGHLADAYCAARSYKKALPLYRKLQKLEPEQNAELAE
KIRHCRQESGEK

Sequences:

>Translated_572_residues
MTKKCLALLSLTLLINACASEHAAGTIPSAGLEAVAAPSAGPGEGRTMYLFALARLRATEGDQDAALVLLRQAMESDPAA
AYLHTAAAQILLQQNKPEEALVESQTAINTDPAFLQAQLLSGNILMTMQREKEAIPYYKKVMELDPTKEEVYLHVAIYYL
KSFEYEQAVDTLKALVKASPDSALGYYYLAKTYEQMRLPREALGYYKKALDLKPDFEQALIEMGISQETQGLIPDAIESY
KGLLDINPANANVVQHLAQLYIQQKRLSEALALLQEKGGKTLENSRKIGLLFLELERYDDAVKTFQEILEVEPASQQVRF
YLATAYEEKDAADLAIAEFLKVPKESPYYPDAVGHLAYLYKEKGTPEKGIALLKEEVKDQPSRVEPYLHLAGLYESMERY
REGVDTLNSMDDKLQNDPRVLFRLGILYDKLGQKEQSVAMMKRVIAATPDDANALNYLGYTYAEMGVNLEEALSYLKKAV
ELKPDDGFIMDSLGWTYFKLKRYNEAVAQLERAAELSDEDATVLGHLADAYCAARSYKKALPLYRKLQKLEPEQNAELAE
KIRHCRQESGEK
>Mature_571_residues
TKKCLALLSLTLLINACASEHAAGTIPSAGLEAVAAPSAGPGEGRTMYLFALARLRATEGDQDAALVLLRQAMESDPAAA
YLHTAAAQILLQQNKPEEALVESQTAINTDPAFLQAQLLSGNILMTMQREKEAIPYYKKVMELDPTKEEVYLHVAIYYLK
SFEYEQAVDTLKALVKASPDSALGYYYLAKTYEQMRLPREALGYYKKALDLKPDFEQALIEMGISQETQGLIPDAIESYK
GLLDINPANANVVQHLAQLYIQQKRLSEALALLQEKGGKTLENSRKIGLLFLELERYDDAVKTFQEILEVEPASQQVRFY
LATAYEEKDAADLAIAEFLKVPKESPYYPDAVGHLAYLYKEKGTPEKGIALLKEEVKDQPSRVEPYLHLAGLYESMERYR
EGVDTLNSMDDKLQNDPRVLFRLGILYDKLGQKEQSVAMMKRVIAATPDDANALNYLGYTYAEMGVNLEEALSYLKKAVE
LKPDDGFIMDSLGWTYFKLKRYNEAVAQLERAAELSDEDATVLGHLADAYCAARSYKKALPLYRKLQKLEPEQNAELAEK
IRHCRQESGEK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 7 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=422, Percent_Identity=23.2227488151659, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI32307150, Length=422, Percent_Identity=23.2227488151659, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI301336134, Length=438, Percent_Identity=21.9178082191781, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI83415184, Length=438, Percent_Identity=21.9178082191781, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI28329439, Length=507, Percent_Identity=21.301775147929, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI28558993, Length=507, Percent_Identity=21.301775147929, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI115532692, Length=357, Percent_Identity=22.1288515406162, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115532690, Length=357, Percent_Identity=22.1288515406162, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17647755, Length=480, Percent_Identity=24.375, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24585827, Length=480, Percent_Identity=24.375, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24585829, Length=480, Percent_Identity=24.375, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 64094; Mature: 63963

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKCLALLSLTLLINACASEHAAGTIPSAGLEAVAAPSAGPGEGRTMYLFALARLRATE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCEEHHHHHHHHHCCC
GDQDAALVLLRQAMESDPAAAYLHTAAAQILLQQNKPEEALVESQTAINTDPAFLQAQLL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
SGNILMTMQREKEAIPYYKKVMELDPTKEEVYLHVAIYYLKSFEYEQAVDTLKALVKASP
CCCEEEEECHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
DSALGYYYLAKTYEQMRLPREALGYYKKALDLKPDFEQALIEMGISQETQGLIPDAIESY
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
KGLLDINPANANVVQHLAQLYIQQKRLSEALALLQEKGGKTLENSRKIGLLFLELERYDD
CCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHH
AVKTFQEILEVEPASQQVRFYLATAYEEKDAADLAIAEFLKVPKESPYYPDAVGHLAYLY
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KEKGTPEKGIALLKEEVKDQPSRVEPYLHLAGLYESMERYREGVDTLNSMDDKLQNDPRV
HCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LFRLGILYDKLGQKEQSVAMMKRVIAATPDDANALNYLGYTYAEMGVNLEEALSYLKKAV
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
ELKPDDGFIMDSLGWTYFKLKRYNEAVAQLERAAELSDEDATVLGHLADAYCAARSYKKA
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LPLYRKLQKLEPEQNAELAEKIRHCRQESGEK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKKCLALLSLTLLINACASEHAAGTIPSAGLEAVAAPSAGPGEGRTMYLFALARLRATE
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCEEHHHHHHHHHCCC
GDQDAALVLLRQAMESDPAAAYLHTAAAQILLQQNKPEEALVESQTAINTDPAFLQAQLL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
SGNILMTMQREKEAIPYYKKVMELDPTKEEVYLHVAIYYLKSFEYEQAVDTLKALVKASP
CCCEEEEECHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
DSALGYYYLAKTYEQMRLPREALGYYKKALDLKPDFEQALIEMGISQETQGLIPDAIESY
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
KGLLDINPANANVVQHLAQLYIQQKRLSEALALLQEKGGKTLENSRKIGLLFLELERYDD
CCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHH
AVKTFQEILEVEPASQQVRFYLATAYEEKDAADLAIAEFLKVPKESPYYPDAVGHLAYLY
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KEKGTPEKGIALLKEEVKDQPSRVEPYLHLAGLYESMERYREGVDTLNSMDDKLQNDPRV
HCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LFRLGILYDKLGQKEQSVAMMKRVIAATPDDANALNYLGYTYAEMGVNLEEALSYLKKAV
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
ELKPDDGFIMDSLGWTYFKLKRYNEAVAQLERAAELSDEDATVLGHLADAYCAARSYKKA
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LPLYRKLQKLEPEQNAELAEKIRHCRQESGEK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]