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The map label for this gene is abcA [H]

Identifier: 197118957

GI number: 197118957

Start: 2990020

End: 2991306

Strand: Reverse

Name: abcA [H]

Synonym: Gbem_2580

Alternate gene names: 197118957

Gene position: 2991306-2990020 (Counterclockwise)

Preceding gene: 197118958

Following gene: 197118956

Centisome position: 64.81

GC content: 57.81

Gene sequence:

>1287_bases
ATGGCCGATACAGTGATACAGGTGGACGGGCTCTGGAAGGAGTACCGTCTCGGCGTAACCAACCACCACTCCCTCACACG
AGACCTGCAGAGCTGGTGGGCCATGGTGCGTGGCAAGGAAGATCCCAATTCCAAGATCGGCGACGGCCCTTCTTCCGGCG
CTCCTCATGCCCCACAGGAGCGCTTCCTAGCCCTTCGAGACGTTTCTTTCGAGGTCAACCGCGGAGACATCGTCGGCGTC
ATCGGGCGAAACGGCGCCGGCAAGTCAACCCTGCTGAAGATCATGTCTCAGGTGACTGTCCCGACCAAGGGAGAGGTGCG
CATCAAGGGCCGCATGTCGAGCCTGCTGGAAATAGGGACCGGATTCCACCCCGAACTGACGGGGAGGGAGAACATCTTCC
TGAACGGCTCGATCCTAGGCATGACCAAGTCGGACGTTCGCGGGAAGCTGGATAAGATCGTCGCCTTTGCAGAGATTGAG
CAATTTCTCGACACGCCGGTGAAGCGGTACTCCTCCGGGATGTACGTACGATTGGCTTTCGCCGTGGCGGCACACCTGGA
ACCTGAGATCCTGGTGGTGGACGAAGTGCTGGCGGTTGGCGACCTTGCCTTCCAAAGGAAATGTCTTGGAAAGATGGAGG
ACATCGGCAAAGAGGGGCGGACCGTGTTGTTTGTCAGCCATAACATGGCTGCAGTGGCAAACCTTTGCAGTACGGCAATT
GTTTTGAAGGAGGGCGCCAAGGTCTTTCAGGGGGAGGTGGCGCAGGGAATCAGTAACTACCTGAGCCTGTTCGCCGGGGA
GGCGACGCGCGACCTTGAAGAGCGTAGCGACCGCAAGGGGAAAGGTGGCGTCAGGATGACGCAGCTCCTTATAGAGGACC
GAAGTGGGAGCGGCATCCCCACTTTCGCCATCGGCACCGAGATCTCATTCAGGATCAGGTATCGCAGTCAGAAGGATGTG
CGCAATCCAAGGGTCGTGATCGGCATTTACGACAGCACCGGGGTTGGCATCACGAGGCTGGACACCCAAATTACCGGGGA
CCTCCCGGCGTCGCTTTCCTCAACGGGGGAAATCGTCTGCAGCACCGCGGCGATGAACCTGGTTCCGGGGAGGTTTTTCC
TCAACGTTGCTTTTTTCAGCTCCGGGGAGATGGAGGATTACCTCTCCAATGCCGCCTTTTTCGATGTCGTTGCTTCAGAT
TTTTTCAACACGGGCAGAACCTTCGACGAGGGAGACGCTGCTCTTTCAAAGTTTCTGGTGAGGCATGATTGGAGGGTAAC
TGGTTGA

Upstream 100 bases:

>100_bases
GCATAGCTGGCTTGTCAGTCTTGCCACTACGATCTGTGTTCTGCTGGTCGGGATACTACTGTTCAGCAAGGTGGAGAAGT
CTTTCATGGATACGGTATAG

Downstream 100 bases:

>100_bases
TGTCGACGACCTCGCAGGATATTGAGTTTGCGCCGACGTCGGTAATGGACCGTGCTGGCAAGGTCTTCTTCCACGGCAAC
AGGGTATACCGGGCCATCCT

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MADTVIQVDGLWKEYRLGVTNHHSLTRDLQSWWAMVRGKEDPNSKIGDGPSSGAPHAPQERFLALRDVSFEVNRGDIVGV
IGRNGAGKSTLLKIMSQVTVPTKGEVRIKGRMSSLLEIGTGFHPELTGRENIFLNGSILGMTKSDVRGKLDKIVAFAEIE
QFLDTPVKRYSSGMYVRLAFAVAAHLEPEILVVDEVLAVGDLAFQRKCLGKMEDIGKEGRTVLFVSHNMAAVANLCSTAI
VLKEGAKVFQGEVAQGISNYLSLFAGEATRDLEERSDRKGKGGVRMTQLLIEDRSGSGIPTFAIGTEISFRIRYRSQKDV
RNPRVVIGIYDSTGVGITRLDTQITGDLPASLSSTGEIVCSTAAMNLVPGRFFLNVAFFSSGEMEDYLSNAAFFDVVASD
FFNTGRTFDEGDAALSKFLVRHDWRVTG

Sequences:

>Translated_428_residues
MADTVIQVDGLWKEYRLGVTNHHSLTRDLQSWWAMVRGKEDPNSKIGDGPSSGAPHAPQERFLALRDVSFEVNRGDIVGV
IGRNGAGKSTLLKIMSQVTVPTKGEVRIKGRMSSLLEIGTGFHPELTGRENIFLNGSILGMTKSDVRGKLDKIVAFAEIE
QFLDTPVKRYSSGMYVRLAFAVAAHLEPEILVVDEVLAVGDLAFQRKCLGKMEDIGKEGRTVLFVSHNMAAVANLCSTAI
VLKEGAKVFQGEVAQGISNYLSLFAGEATRDLEERSDRKGKGGVRMTQLLIEDRSGSGIPTFAIGTEISFRIRYRSQKDV
RNPRVVIGIYDSTGVGITRLDTQITGDLPASLSSTGEIVCSTAAMNLVPGRFFLNVAFFSSGEMEDYLSNAAFFDVVASD
FFNTGRTFDEGDAALSKFLVRHDWRVTG
>Mature_427_residues
ADTVIQVDGLWKEYRLGVTNHHSLTRDLQSWWAMVRGKEDPNSKIGDGPSSGAPHAPQERFLALRDVSFEVNRGDIVGVI
GRNGAGKSTLLKIMSQVTVPTKGEVRIKGRMSSLLEIGTGFHPELTGRENIFLNGSILGMTKSDVRGKLDKIVAFAEIEQ
FLDTPVKRYSSGMYVRLAFAVAAHLEPEILVVDEVLAVGDLAFQRKCLGKMEDIGKEGRTVLFVSHNMAAVANLCSTAIV
LKEGAKVFQGEVAQGISNYLSLFAGEATRDLEERSDRKGKGGVRMTQLLIEDRSGSGIPTFAIGTEISFRIRYRSQKDVR
NPRVVIGIYDSTGVGITRLDTQITGDLPASLSSTGEIVCSTAAMNLVPGRFFLNVAFFSSGEMEDYLSNAAFFDVVASDF
FNTGRTFDEGDAALSKFLVRHDWRVTG

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=189, Percent_Identity=30.6878306878307, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI27477115, Length=226, Percent_Identity=30.0884955752212, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI153792144, Length=198, Percent_Identity=26.7676767676768, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI6005701, Length=191, Percent_Identity=27.2251308900524, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI150417984, Length=197, Percent_Identity=26.3959390862944, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI47078218, Length=200, Percent_Identity=28.5, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI45446740, Length=200, Percent_Identity=28.5, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI31657092, Length=202, Percent_Identity=25.2475247524752, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI30795238, Length=199, Percent_Identity=22.6130653266332, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI27881501, Length=199, Percent_Identity=22.6130653266332, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI105990541, Length=200, Percent_Identity=25.5, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI27262624, Length=195, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI27262626, Length=195, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786398, Length=212, Percent_Identity=29.2452830188679, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081709, Length=218, Percent_Identity=23.8532110091743, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788210, Length=203, Percent_Identity=30.5418719211823, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790525, Length=254, Percent_Identity=27.5590551181102, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786319, Length=196, Percent_Identity=26.0204081632653, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789962, Length=223, Percent_Identity=25.5605381165919, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787089, Length=225, Percent_Identity=23.1111111111111, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994943, Length=205, Percent_Identity=24.8780487804878, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788761, Length=200, Percent_Identity=24, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790467, Length=216, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081791, Length=215, Percent_Identity=20.9302325581395, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789032, Length=214, Percent_Identity=22.4299065420561, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789891, Length=229, Percent_Identity=23.1441048034935, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790190, Length=309, Percent_Identity=23.6245954692557, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788225, Length=209, Percent_Identity=25.8373205741627, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787029, Length=196, Percent_Identity=24.4897959183673, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788897, Length=230, Percent_Identity=24.7826086956522, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87081782, Length=230, Percent_Identity=23.9130434782609, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI48995001, Length=201, Percent_Identity=25.8706467661692, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786253, Length=195, Percent_Identity=28.7179487179487, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1789873, Length=201, Percent_Identity=28.3582089552239, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI48994997, Length=218, Percent_Identity=28.8990825688073, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI115533608, Length=203, Percent_Identity=25.1231527093596, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17565586, Length=195, Percent_Identity=25.1282051282051, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007184, Length=231, Percent_Identity=26.4069264069264, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221500365, Length=231, Percent_Identity=26.4069264069264, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666092, Length=211, Percent_Identity=28.436018957346, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648314, Length=197, Percent_Identity=26.3959390862944, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573571, Length=207, Percent_Identity=23.6714975845411, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28573573, Length=207, Percent_Identity=23.6714975845411, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221512771, Length=209, Percent_Identity=26.7942583732057, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24643674, Length=238, Percent_Identity=24.7899159663866, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 46743; Mature: 46612

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTVIQVDGLWKEYRLGVTNHHSLTRDLQSWWAMVRGKEDPNSKIGDGPSSGAPHAPQE
CCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
RFLALRDVSFEVNRGDIVGVIGRNGAGKSTLLKIMSQVTVPTKGEVRIKGRMSSLLEIGT
HHEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCC
GFHPELTGRENIFLNGSILGMTKSDVRGKLDKIVAFAEIEQFLDTPVKRYSSGMYVRLAF
CCCCCCCCCCEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEE
AVAAHLEPEILVVDEVLAVGDLAFQRKCLGKMEDIGKEGRTVLFVSHNMAAVANLCSTAI
HHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
VLKEGAKVFQGEVAQGISNYLSLFAGEATRDLEERSDRKGKGGVRMTQLLIEDRSGSGIP
HHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCC
TFAIGTEISFRIRYRSQKDVRNPRVVIGIYDSTGVGITRLDTQITGDLPASLSSTGEIVC
EEEECCEEEEEEEECCCCCCCCCEEEEEEECCCCCCEEEECCEECCCCCCCCCCCCCEEE
STAAMNLVPGRFFLNVAFFSSGEMEDYLSNAAFFDVVASDFFNTGRTFDEGDAALSKFLV
EHHHHHHCCCEEEEEEEEECCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
RHDWRVTG
HCCCEECC
>Mature Secondary Structure 
ADTVIQVDGLWKEYRLGVTNHHSLTRDLQSWWAMVRGKEDPNSKIGDGPSSGAPHAPQE
CCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
RFLALRDVSFEVNRGDIVGVIGRNGAGKSTLLKIMSQVTVPTKGEVRIKGRMSSLLEIGT
HHEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCC
GFHPELTGRENIFLNGSILGMTKSDVRGKLDKIVAFAEIEQFLDTPVKRYSSGMYVRLAF
CCCCCCCCCCEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEE
AVAAHLEPEILVVDEVLAVGDLAFQRKCLGKMEDIGKEGRTVLFVSHNMAAVANLCSTAI
HHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHH
VLKEGAKVFQGEVAQGISNYLSLFAGEATRDLEERSDRKGKGGVRMTQLLIEDRSGSGIP
HHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCC
TFAIGTEISFRIRYRSQKDVRNPRVVIGIYDSTGVGITRLDTQITGDLPASLSSTGEIVC
EEEECCEEEEEEEECCCCCCCCCEEEEEEECCCCCCEEEECCEECCCCCCCCCCCCCEEE
STAAMNLVPGRFFLNVAFFSSGEMEDYLSNAAFFDVVASDFFNTGRTFDEGDAALSKFLV
EHHHHHHCCCEEEEEEEEECCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
RHDWRVTG
HCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]