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The map label for this gene is atoS [H]

Identifier: 197118911

GI number: 197118911

Start: 2934457

End: 2935833

Strand: Reverse

Name: atoS [H]

Synonym: Gbem_2534

Alternate gene names: 197118911

Gene position: 2935833-2934457 (Counterclockwise)

Preceding gene: 197118912

Following gene: 308535305

Centisome position: 63.61

GC content: 50.54

Gene sequence:

>1377_bases
ATGAAATTGCTCGTCGTTGACGACAACAGTAATGATCGAAAACTGTTGCGCTTAACCCTGGAGCACCACGGTTTTGAGAC
CATCTGGGAAGCCAGCAACGGCGAGGAGGCCTATGAGACGGCTCAGATCAACAAGCCGGACCTGATCATCTCGGACGCCT
TGATGCCGCGGATGGATGGATTTCAGTTCCTGCGTCTGATCAAGATGGAACCGGAACTCAAAGACATCCCGTTTATCTTC
TACTCCGCCGTCTATACCGGCTACAAGGAAGAGGAACTGGCCCTCTCGCTCGGTGCCGAGACTTTTATCGTTAAGCCGAA
GGAGCCGGAAGAGTTGTGGAACCTCATTGCTGCCGTCCTGGAGAAACTATCGGCAGGGAAAAAAGCAAGCCAGTACGTTG
AGCCCGTGGAAGAGGAAAAGCACTTCCTCAAAAAGTATGACGAAATCGTAACGGCGAAGCTCGAGGAGAAGGTCGGGGAG
CTTCAAGACGCTCTGACCCGTCTTAAGGAGGCCGAAGCGGTCTTATTAAAAACAAATGAAGAGTTGGAAAAACGGGTCGC
CGGGCGGACCAGGGAACTGGAAATAAATCGTTCGGAACTTGCCGCGCAAAACGTGGAACTGTCGAAAACCTATCACGATT
TGGAGACTCAAACGGCGGAACGGATCCGGGCGATGGAAGAACTCCGGGAAAAGGACCAGATGCTGACTCAGCAGAGCCGA
GTGGCGGCGATGGGTGAGATGCTGAGCAACATTGCCCATCACTGGCGCCAACCGCTCAACGTCGTCGCACTGAAGCTTCA
GGAACTGGAAATGGTCAAGGAATTGGACCATGAATTCCTTGATGCCAACGTCGGCGAAGCCCTGAAAATCATCTTTCAAT
TGTCCAAGACTATCGATGATTTCCGTGTTTTCTCTGCTCCCGACACACAGAAGTCATTGTTCAATGTGGAACAGATTATA
GCGAAAGCAGTTTCTTTCATAGAAGAAAGTTTCAAGGAACAGCAAATTGCCATAGATGTCAGTTCAACTGGTCAACCTCA
AGTTGACGGGTATTCAAACGAATTTGGTCAGGTGATCTTGAACATACTGTTGAACGCCAGGGATACCATTTTTGAGAGAC
GGACGCTCAATGCCCGGGTTGCCGTGCGTTCATGGACAGAAAATGGCAGGGTAGTAGTAACGATTACCGACACAGCCGGA
GGCATCGAGGAAGGAATCATCGGTAAAATATTTGACCCCTTTTTTACAACCAAAGCCCAGGGGAAGGGATCCGGGGTCGG
TCTGTTCATGTCCAAAACGATCATCGAGACAAAAATGGGGGGGCGTTTAACCGCTCGGAATGTCAACGACGGTGCAGAGT
TCAGGATCGAGATCTGA

Upstream 100 bases:

>100_bases
GACGGCTATTTCGAAAAGCCCATCGATCCGATTACCATCGTCGAGCAGATCGAGAAGGCTGTGGGAATTTCCCGCGCCAC
TAAATGAATGGAGTCTGACA

Downstream 100 bases:

>100_bases
AATGAAAAGGGCCGTGGCGTAATGCCGCGGCCCTTTCTTTCTATGGAATGCCGGTTAGATCTTATGCTGCCTTGCGCTTG
CGCCACACAGCCAGACCCGC

Product: response receiver histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKLLVVDDNSNDRKLLRLTLEHHGFETIWEASNGEEAYETAQINKPDLIISDALMPRMDGFQFLRLIKMEPELKDIPFIF
YSAVYTGYKEEELALSLGAETFIVKPKEPEELWNLIAAVLEKLSAGKKASQYVEPVEEEKHFLKKYDEIVTAKLEEKVGE
LQDALTRLKEAEAVLLKTNEELEKRVAGRTRELEINRSELAAQNVELSKTYHDLETQTAERIRAMEELREKDQMLTQQSR
VAAMGEMLSNIAHHWRQPLNVVALKLQELEMVKELDHEFLDANVGEALKIIFQLSKTIDDFRVFSAPDTQKSLFNVEQII
AKAVSFIEESFKEQQIAIDVSSTGQPQVDGYSNEFGQVILNILLNARDTIFERRTLNARVAVRSWTENGRVVVTITDTAG
GIEEGIIGKIFDPFFTTKAQGKGSGVGLFMSKTIIETKMGGRLTARNVNDGAEFRIEI

Sequences:

>Translated_458_residues
MKLLVVDDNSNDRKLLRLTLEHHGFETIWEASNGEEAYETAQINKPDLIISDALMPRMDGFQFLRLIKMEPELKDIPFIF
YSAVYTGYKEEELALSLGAETFIVKPKEPEELWNLIAAVLEKLSAGKKASQYVEPVEEEKHFLKKYDEIVTAKLEEKVGE
LQDALTRLKEAEAVLLKTNEELEKRVAGRTRELEINRSELAAQNVELSKTYHDLETQTAERIRAMEELREKDQMLTQQSR
VAAMGEMLSNIAHHWRQPLNVVALKLQELEMVKELDHEFLDANVGEALKIIFQLSKTIDDFRVFSAPDTQKSLFNVEQII
AKAVSFIEESFKEQQIAIDVSSTGQPQVDGYSNEFGQVILNILLNARDTIFERRTLNARVAVRSWTENGRVVVTITDTAG
GIEEGIIGKIFDPFFTTKAQGKGSGVGLFMSKTIIETKMGGRLTARNVNDGAEFRIEI
>Mature_458_residues
MKLLVVDDNSNDRKLLRLTLEHHGFETIWEASNGEEAYETAQINKPDLIISDALMPRMDGFQFLRLIKMEPELKDIPFIF
YSAVYTGYKEEELALSLGAETFIVKPKEPEELWNLIAAVLEKLSAGKKASQYVEPVEEEKHFLKKYDEIVTAKLEEKVGE
LQDALTRLKEAEAVLLKTNEELEKRVAGRTRELEINRSELAAQNVELSKTYHDLETQTAERIRAMEELREKDQMLTQQSR
VAAMGEMLSNIAHHWRQPLNVVALKLQELEMVKELDHEFLDANVGEALKIIFQLSKTIDDFRVFSAPDTQKSLFNVEQII
AKAVSFIEESFKEQQIAIDVSSTGQPQVDGYSNEFGQVILNILLNARDTIFERRTLNARVAVRSWTENGRVVVTITDTAG
GIEEGIIGKIFDPFFTTKAQGKGSGVGLFMSKTIIETKMGGRLTARNVNDGAEFRIEI

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=275, Percent_Identity=29.0909090909091, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786599, Length=125, Percent_Identity=33.6, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788191, Length=125, Percent_Identity=32.8, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51944; Mature: 51944

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLVVDDNSNDRKLLRLTLEHHGFETIWEASNGEEAYETAQINKPDLIISDALMPRMDG
CEEEEEECCCCCCCCEEEEHHHCCCHHEECCCCCCHHHHHHCCCCCCEEEECHHHCCCCH
FQFLRLIKMEPELKDIPFIFYSAVYTGYKEEELALSLGAETFIVKPKEPEELWNLIAAVL
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHEECCCEEEECCCCHHHHHHHHHHHH
EKLSAGKKASQYVEPVEEEKHFLKKYDEIVTAKLEEKVGELQDALTRLKEAEAVLLKTNE
HHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCH
ELEKRVAGRTRELEINRSELAAQNVELSKTYHDLETQTAERIRAMEELREKDQMLTQQSR
HHHHHHCCCCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAMGEMLSNIAHHWRQPLNVVALKLQELEMVKELDHEFLDANVGEALKIIFQLSKTIDD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FRVFSAPDTQKSLFNVEQIIAKAVSFIEESFKEQQIAIDVSSTGQPQVDGYSNEFGQVIL
HEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHH
NILLNARDTIFERRTLNARVAVRSWTENGRVVVTITDTAGGIEEGIIGKIFDPFFTTKAQ
HHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCHHCCHHHHHCHHHCCCCC
GKGSGVGLFMSKTIIETKMGGRLTARNVNDGAEFRIEI
CCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCCEEEEC
>Mature Secondary Structure
MKLLVVDDNSNDRKLLRLTLEHHGFETIWEASNGEEAYETAQINKPDLIISDALMPRMDG
CEEEEEECCCCCCCCEEEEHHHCCCHHEECCCCCCHHHHHHCCCCCCEEEECHHHCCCCH
FQFLRLIKMEPELKDIPFIFYSAVYTGYKEEELALSLGAETFIVKPKEPEELWNLIAAVL
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHEECCCEEEECCCCHHHHHHHHHHHH
EKLSAGKKASQYVEPVEEEKHFLKKYDEIVTAKLEEKVGELQDALTRLKEAEAVLLKTNE
HHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCH
ELEKRVAGRTRELEINRSELAAQNVELSKTYHDLETQTAERIRAMEELREKDQMLTQQSR
HHHHHHCCCCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAMGEMLSNIAHHWRQPLNVVALKLQELEMVKELDHEFLDANVGEALKIIFQLSKTIDD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FRVFSAPDTQKSLFNVEQIIAKAVSFIEESFKEQQIAIDVSSTGQPQVDGYSNEFGQVIL
HEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHH
NILLNARDTIFERRTLNARVAVRSWTENGRVVVTITDTAGGIEEGIIGKIFDPFFTTKAQ
HHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCHHCCHHHHHCHHHCCCCC
GKGSGVGLFMSKTIIETKMGGRLTARNVNDGAEFRIEI
CCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]