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The map label for this gene is ppiD [H]

Identifier: 197118887

GI number: 197118887

Start: 2910144

End: 2911724

Strand: Direct

Name: ppiD [H]

Synonym: Gbem_2510

Alternate gene names: 197118887

Gene position: 2910144-2911724 (Clockwise)

Preceding gene: 197118880

Following gene: 197118888

Centisome position: 63.06

GC content: 59.84

Gene sequence:

>1581_bases
ATGCTAGGCATAATGAGGAAGTACAAGCAATCGATACTCATAAAGATTGTATTCGTCGTGATAGTACTCTCTTTCATAGG
GACCATCTTCCTCGTCTGGGGCAGGGGCGGAGACAAATCCGCTAACGGTCCTGCTGGATATGCCGCAATGGTTGACGGCA
CCAAGATCTCGATGGATGATTTCCAGAAGAACTACTACCGCACCAGGAACCTGTACGAGCAGATCTACGGCCGCTCGCTG
ACCCCGGAGATGGAAAAGCAGATGGGGCTCAAAAAGGCGACCATAAGCAGCATGATTGACAACGTCCTCACCCTCAAAGA
AGCCAAGAAGATGGGCATCAAGGTGGATAAGGACGAGGTGGCCGCGGAGATCGCCAAGATCCCCTCCTTCCAGAACAACG
GCGCTTTCGACTTCACCCTGTACCAGAACACCCTCAAGGCCAATCGGGTCACCCCGAAGGAGTTCGAGGAAACCCAGGAA
CAGGACCTCCTGGTGCAAAAGGCGCGCAACAAGGTAAAGGAGAAGGCGACTGTCACCGACGCGGACCTGATGCAGGAGTT
CAAGAAGCAAAACGACAAGGTCAACCTTCAGTACGTCTCCTTCTCCCCCGCCGACGTGAAGGGAAGCATCAAGCTGACCG
ACGCCGAGCTGAACGTCTACCTCCAGGACCACCAGGCGCAGTTCAAGACGCCGGAGCAGGTATCGATCGCCTACACGCTG
GTGAGCCCGGCAGCCCTTGCCGCCAAGGTGAGCGTCACCCCCGAAGAAGCTCAGAACTATTACCAGAAGAACATCGACCG
CTACCAGGGCAAAGGGGGCATCCTCCCGTTCGCCGAGGTCAAGGATCAGGCGACCGCCGACGCGCAGAAAGCCAAGGCCG
CCAAGGAAGCCTACGAGAAGGCGGCCGAGACGGCCAAGAAGTTCCGCGCCCAGGGCAACCTCGATGCCGCCGCCCAAGCG
CTTGGCGGCAAGGTCGAGAAGACCCCGCTCTTTACCGCGCAGGCGCCTGCCGCTGCCATCGCAGGGGAGACCGAGCTCGT
CGCCCGCGCCTTCGCGCTGAAGCAGAACGAGCTGGGGGGACCGGTGGAGACCGCCAAGGGGATCTACCTGCTGAAGGTTC
TCGACAAGAAGCCGTCCGTCGTGCCGCCGCTGGCGCAGGTAAGGGCGCAGGTCGAGCGGAAGCTTTTGGAAGTGAAAGGG
GCCGAGGTAGCCAAGAAGAAGGCTGAAGAAGCGCTGCAGCAGCTCTCCAAAGCGGGCGCGGCCACCAAGGAGACCGGCAA
CTTCGGCTACTCCCCGGCCGGCGCCATCCCCACCGTCGGAACCTCCCCCGAGCTGATGGAAGCCGCTTTCGCGCTTACCC
CTGCCAACCCGGTCGCCAAGCAGCCGGTCAAGGTGGGCGAACGCTGGTACGCGGTGAAACTGAAGAACAGGGTGGAAGCG
CCCACCACAGACTTCGCCAAGGCCTCCGCAACCATCAAGCAGACCCTGCTCCCCAAAAAGCAGCAGGAAGAGCTGGACAA
GTGGTTGAAAGGGCTCAGGGATAAGGCTAAAATCGACATCAACCCGTCGATCAAGGACTAA

Upstream 100 bases:

>100_bases
CATCATTCTGGTATTGCTTTTACGATTAAATCATACTATTATTCCCAACTCTTGTGATACATGAGAGACCACTCTATCAG
CGCAAAGGAGCCGAACTGGA

Downstream 100 bases:

>100_bases
CTAAAGCAACAACGCGGCAAATCGACAGCTATTCAAGTGCGAGGTGGAGGGTGCAGGTGCACGCTTCACCTTTCACTTTT
AACGCTTGAAGCGCGAACCA

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MLGIMRKYKQSILIKIVFVVIVLSFIGTIFLVWGRGGDKSANGPAGYAAMVDGTKISMDDFQKNYYRTRNLYEQIYGRSL
TPEMEKQMGLKKATISSMIDNVLTLKEAKKMGIKVDKDEVAAEIAKIPSFQNNGAFDFTLYQNTLKANRVTPKEFEETQE
QDLLVQKARNKVKEKATVTDADLMQEFKKQNDKVNLQYVSFSPADVKGSIKLTDAELNVYLQDHQAQFKTPEQVSIAYTL
VSPAALAAKVSVTPEEAQNYYQKNIDRYQGKGGILPFAEVKDQATADAQKAKAAKEAYEKAAETAKKFRAQGNLDAAAQA
LGGKVEKTPLFTAQAPAAAIAGETELVARAFALKQNELGGPVETAKGIYLLKVLDKKPSVVPPLAQVRAQVERKLLEVKG
AEVAKKKAEEALQQLSKAGAATKETGNFGYSPAGAIPTVGTSPELMEAAFALTPANPVAKQPVKVGERWYAVKLKNRVEA
PTTDFAKASATIKQTLLPKKQQEELDKWLKGLRDKAKIDINPSIKD

Sequences:

>Translated_526_residues
MLGIMRKYKQSILIKIVFVVIVLSFIGTIFLVWGRGGDKSANGPAGYAAMVDGTKISMDDFQKNYYRTRNLYEQIYGRSL
TPEMEKQMGLKKATISSMIDNVLTLKEAKKMGIKVDKDEVAAEIAKIPSFQNNGAFDFTLYQNTLKANRVTPKEFEETQE
QDLLVQKARNKVKEKATVTDADLMQEFKKQNDKVNLQYVSFSPADVKGSIKLTDAELNVYLQDHQAQFKTPEQVSIAYTL
VSPAALAAKVSVTPEEAQNYYQKNIDRYQGKGGILPFAEVKDQATADAQKAKAAKEAYEKAAETAKKFRAQGNLDAAAQA
LGGKVEKTPLFTAQAPAAAIAGETELVARAFALKQNELGGPVETAKGIYLLKVLDKKPSVVPPLAQVRAQVERKLLEVKG
AEVAKKKAEEALQQLSKAGAATKETGNFGYSPAGAIPTVGTSPELMEAAFALTPANPVAKQPVKVGERWYAVKLKNRVEA
PTTDFAKASATIKQTLLPKKQQEELDKWLKGLRDKAKIDINPSIKD
>Mature_526_residues
MLGIMRKYKQSILIKIVFVVIVLSFIGTIFLVWGRGGDKSANGPAGYAAMVDGTKISMDDFQKNYYRTRNLYEQIYGRSL
TPEMEKQMGLKKATISSMIDNVLTLKEAKKMGIKVDKDEVAAEIAKIPSFQNNGAFDFTLYQNTLKANRVTPKEFEETQE
QDLLVQKARNKVKEKATVTDADLMQEFKKQNDKVNLQYVSFSPADVKGSIKLTDAELNVYLQDHQAQFKTPEQVSIAYTL
VSPAALAAKVSVTPEEAQNYYQKNIDRYQGKGGILPFAEVKDQATADAQKAKAAKEAYEKAAETAKKFRAQGNLDAAAQA
LGGKVEKTPLFTAQAPAAAIAGETELVARAFALKQNELGGPVETAKGIYLLKVLDKKPSVVPPLAQVRAQVERKLLEVKG
AEVAKKKAEEALQQLSKAGAATKETGNFGYSPAGAIPTVGTSPELMEAAFALTPANPVAKQPVKVGERWYAVKLKNRVEA
PTTDFAKASATIKQTLLPKKQQEELDKWLKGLRDKAKIDINPSIKD

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=280, Percent_Identity=24.6428571428571, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 57644; Mature: 57644

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGIMRKYKQSILIKIVFVVIVLSFIGTIFLVWGRGGDKSANGPAGYAAMVDGTKISMDD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEECCCEECHHH
FQKNYYRTRNLYEQIYGRSLTPEMEKQMGLKKATISSMIDNVLTLKEAKKMGIKVDKDEV
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEECHHHH
AAEIAKIPSFQNNGAFDFTLYQNTLKANRVTPKEFEETQEQDLLVQKARNKVKEKATVTD
HHHHHHCCCCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ADLMQEFKKQNDKVNLQYVSFSPADVKGSIKLTDAELNVYLQDHQAQFKTPEQVSIAYTL
HHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEECEEEEEEECCHHHCCCCCCEEEEEEE
VSPAALAAKVSVTPEEAQNYYQKNIDRYQGKGGILPFAEVKDQATADAQKAKAAKEAYEK
CCCHHHHEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAETAKKFRAQGNLDAAAQALGGKVEKTPLFTAQAPAAAIAGETELVARAFALKQNELGG
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEECCCCHHHHCCHHHHHHHHHHHHHCCCCC
PVETAKGIYLLKVLDKKPSVVPPLAQVRAQVERKLLEVKGAEVAKKKAEEALQQLSKAGA
CHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
ATKETGNFGYSPAGAIPTVGTSPELMEAAFALTPANPVAKQPVKVGERWYAVKLKNRVEA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEEECCCCCC
PTTDFAKASATIKQTLLPKKQQEELDKWLKGLRDKAKIDINPSIKD
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCC
>Mature Secondary Structure
MLGIMRKYKQSILIKIVFVVIVLSFIGTIFLVWGRGGDKSANGPAGYAAMVDGTKISMDD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEECCCEECHHH
FQKNYYRTRNLYEQIYGRSLTPEMEKQMGLKKATISSMIDNVLTLKEAKKMGIKVDKDEV
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEECHHHH
AAEIAKIPSFQNNGAFDFTLYQNTLKANRVTPKEFEETQEQDLLVQKARNKVKEKATVTD
HHHHHHCCCCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ADLMQEFKKQNDKVNLQYVSFSPADVKGSIKLTDAELNVYLQDHQAQFKTPEQVSIAYTL
HHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEECEEEEEEECCHHHCCCCCCEEEEEEE
VSPAALAAKVSVTPEEAQNYYQKNIDRYQGKGGILPFAEVKDQATADAQKAKAAKEAYEK
CCCHHHHEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAETAKKFRAQGNLDAAAQALGGKVEKTPLFTAQAPAAAIAGETELVARAFALKQNELGG
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEECCCCHHHHCCHHHHHHHHHHHHHCCCCC
PVETAKGIYLLKVLDKKPSVVPPLAQVRAQVERKLLEVKGAEVAKKKAEEALQQLSKAGA
CHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
ATKETGNFGYSPAGAIPTVGTSPELMEAAFALTPANPVAKQPVKVGERWYAVKLKNRVEA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEEECCCCCC
PTTDFAKASATIKQTLLPKKQQEELDKWLKGLRDKAKIDINPSIKD
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]