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The map label for this gene is zraS [C]

Identifier: 197118871

GI number: 197118871

Start: 2888585

End: 2890576

Strand: Reverse

Name: zraS [C]

Synonym: Gbem_2494

Alternate gene names: 197118871

Gene position: 2890576-2888585 (Counterclockwise)

Preceding gene: 197118872

Following gene: 197118863

Centisome position: 62.63

GC content: 63.2

Gene sequence:

>1992_bases
ATGAAAATTCTCGCCATAGACGACAACCACGACAATCTCCTCACGCTGAAGGCGCTGCTGAAGATTTTCATGCCCGAAGC
AAACCTCATCACCTCCGCCTCGGCCCAGGACGGCATCCGCAGGGCGCTGCTGGAGGCGCCCGACACCATCCTTTTGGACA
TCCAGATGCCGGTCATGGACGGATACGAGGCGACCCGCAGGCTCAAGGGAAACCCCTCCACCCAACATATCCCCATCATC
CTGGTCACCGCGCATCGCACCGATCCCTCCGGCAAGGTGCGGGGGCTCGAGTGCGGCGCCGACGCGTTCCTCTCCAAGCC
CATCGACGAGGCTGAACTTGTGGCCCAGATCAGGGCGATGGTGCGGATCAAGCGTTCCGAGGACGCGCTGCGGCAAGAGC
GGGACAGCCTGGAGGCTCTGGTGCAGAAACGGACTTCGGAGCTGCTGCTCATGAACCAGGTGCTGACGGAGAACCTGGCA
CGCCTTGCCGAGAACGAGGCGCGCTACACCCGGGCGGTGCGGGGGACGACGGACGGGCTTTGGGACTGGAACGTGGTGAC
CGGCGAGTGCTATTTTTCCCCGCGCTGGAAGGAACTCTTGGGCTTTGCCGACGACGAACTGGAGAACCGAGTCGATACCT
TCTATTCGCGGCTGCATCCAGACGATATGGCCGTGGCGCAGGAGGCGCTCGAATCGCACCTGTCCGGGAAAACGTCCCTG
GACGTGGAGCTCAGGCTTAGGAACCGCGAGGGAGGGTACCTGCGCTTTCGGGTCCGCGGGCAGGCGGAGTGGGACAGCCT
GGGGGCGGCCGTTCGCCTCTCCGGAGCCCTTTCCGACGTCACCGAGCGGCAGCTCATGGAGGAGCAGCTCCGGCAGTCGC
AGAAGATGGAGGCGGTAGGGCAGCTGGCTGGAGGTGTCGCGCACGACTTCAACAACATCCTCACCGTGATCGCAGGCTAC
GCCAACATGCTCATGATGGACCTCCCAGCGCTTGGGAACGAAGTGAGGCTGGCCGAACAGATCGCCATCGCCACCGAGAG
GGCTGCCGAACTGACCAAGGGGCTTCTGGCTTTCAGCCGGAAGCAGCCGATGGCGCCTCAGAAGCTGGACCTGGGGGAGA
TCGTGCAGCGCGTGGAGACCTTCCTCACCCGCGTGATAGGGGAGGACATCCAGCTGAAGACGCATCTGCTCCCGGACTCT
CTGCCGGTCTGGGTCGACATGGGGCAGATCGAACAGGTGCTCATCAACCTGGCCGCCAATGCGCGCGACGCCATGGAAAA
CGGAGGGACCTTCACCATCGCGACCGGCCTCTTCGAAGACGACTCGCTTTCCGCCTTCTGCGGCCCGGCAGGGAGCTATG
CCGTGATCATCGTGTCCGACAACGGCAAGGGGATGCCCGCCGAGATCAGCAAGCGGATCTTCGAGCCTTTCTTCACCACC
AAGGAGGTGGGGAAGGGTACGGGGCTCGGCATGGCGATCGTCTACGGTATCGTGCAGCAGCACAGGGGTTACATCACCGT
CGACAGCAAACCCGGGGACGGCACCGTCTTCAGCATCTATCTGCCGCTTGCCGCAGACTGCGCCGAAATGTACCAGGAGC
CGGCGGTCGACCAGGAGCCGGAAATGGGGACCGAGACCATCCTGGTCGCCGAAGACGACCCGAGCGTGCGCAACCTGGTG
GACATGGTGCTGACCAAGCACGGCTACCAGGTGATCCTGGCTGAGAACGGGCAGGAGGTGGTCGAGCGCTTCACCGCCCA
CTCAAGCGACATCGGGTTGATCCTGATGGACATCATCATGCCGCGCAAAAACGGCATAGAGGCGTTCGCGGAGATCAAGA
AGCTGCAGCCGGAGGCGAAGGTCCTCTTCACCAGCGGCTACACCTCCGATTTCATCCAGAGCCGCGGCATGGAAGACGGG
GTCGAGCTGATCATGAAGCCGGTGCAGCCGGCCCAACTGCTGCGCAAGGTGAGGGAAGTGCTGGAGAGGTGA

Upstream 100 bases:

>100_bases
GAAGAGTTGCAGGAACTGGTCACCAAATTCGTCGCAGCGGGGACTGCGCCAAACGGGAAGTAAAACCGGCCCCCCTTTTA
GCAGTCGAGGAAACCGTTAA

Downstream 100 bases:

>100_bases
TTCCGGATTTCCGGAGACAAGAAAAGGGGAGCGCCTGTTAGCGGCGCTCCCCTTTTTAATTCCTGCCCTTTCCTGCTTCT
GTCTCAGGCGAAGTCCCGGG

Product: response receiver sensor histidine kinase response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MKILAIDDNHDNLLTLKALLKIFMPEANLITSASAQDGIRRALLEAPDTILLDIQMPVMDGYEATRRLKGNPSTQHIPII
LVTAHRTDPSGKVRGLECGADAFLSKPIDEAELVAQIRAMVRIKRSEDALRQERDSLEALVQKRTSELLLMNQVLTENLA
RLAENEARYTRAVRGTTDGLWDWNVVTGECYFSPRWKELLGFADDELENRVDTFYSRLHPDDMAVAQEALESHLSGKTSL
DVELRLRNREGGYLRFRVRGQAEWDSLGAAVRLSGALSDVTERQLMEEQLRQSQKMEAVGQLAGGVAHDFNNILTVIAGY
ANMLMMDLPALGNEVRLAEQIAIATERAAELTKGLLAFSRKQPMAPQKLDLGEIVQRVETFLTRVIGEDIQLKTHLLPDS
LPVWVDMGQIEQVLINLAANARDAMENGGTFTIATGLFEDDSLSAFCGPAGSYAVIIVSDNGKGMPAEISKRIFEPFFTT
KEVGKGTGLGMAIVYGIVQQHRGYITVDSKPGDGTVFSIYLPLAADCAEMYQEPAVDQEPEMGTETILVAEDDPSVRNLV
DMVLTKHGYQVILAENGQEVVERFTAHSSDIGLILMDIIMPRKNGIEAFAEIKKLQPEAKVLFTSGYTSDFIQSRGMEDG
VELIMKPVQPAQLLRKVREVLER

Sequences:

>Translated_663_residues
MKILAIDDNHDNLLTLKALLKIFMPEANLITSASAQDGIRRALLEAPDTILLDIQMPVMDGYEATRRLKGNPSTQHIPII
LVTAHRTDPSGKVRGLECGADAFLSKPIDEAELVAQIRAMVRIKRSEDALRQERDSLEALVQKRTSELLLMNQVLTENLA
RLAENEARYTRAVRGTTDGLWDWNVVTGECYFSPRWKELLGFADDELENRVDTFYSRLHPDDMAVAQEALESHLSGKTSL
DVELRLRNREGGYLRFRVRGQAEWDSLGAAVRLSGALSDVTERQLMEEQLRQSQKMEAVGQLAGGVAHDFNNILTVIAGY
ANMLMMDLPALGNEVRLAEQIAIATERAAELTKGLLAFSRKQPMAPQKLDLGEIVQRVETFLTRVIGEDIQLKTHLLPDS
LPVWVDMGQIEQVLINLAANARDAMENGGTFTIATGLFEDDSLSAFCGPAGSYAVIIVSDNGKGMPAEISKRIFEPFFTT
KEVGKGTGLGMAIVYGIVQQHRGYITVDSKPGDGTVFSIYLPLAADCAEMYQEPAVDQEPEMGTETILVAEDDPSVRNLV
DMVLTKHGYQVILAENGQEVVERFTAHSSDIGLILMDIIMPRKNGIEAFAEIKKLQPEAKVLFTSGYTSDFIQSRGMEDG
VELIMKPVQPAQLLRKVREVLER
>Mature_663_residues
MKILAIDDNHDNLLTLKALLKIFMPEANLITSASAQDGIRRALLEAPDTILLDIQMPVMDGYEATRRLKGNPSTQHIPII
LVTAHRTDPSGKVRGLECGADAFLSKPIDEAELVAQIRAMVRIKRSEDALRQERDSLEALVQKRTSELLLMNQVLTENLA
RLAENEARYTRAVRGTTDGLWDWNVVTGECYFSPRWKELLGFADDELENRVDTFYSRLHPDDMAVAQEALESHLSGKTSL
DVELRLRNREGGYLRFRVRGQAEWDSLGAAVRLSGALSDVTERQLMEEQLRQSQKMEAVGQLAGGVAHDFNNILTVIAGY
ANMLMMDLPALGNEVRLAEQIAIATERAAELTKGLLAFSRKQPMAPQKLDLGEIVQRVETFLTRVIGEDIQLKTHLLPDS
LPVWVDMGQIEQVLINLAANARDAMENGGTFTIATGLFEDDSLSAFCGPAGSYAVIIVSDNGKGMPAEISKRIFEPFFTT
KEVGKGTGLGMAIVYGIVQQHRGYITVDSKPGDGTVFSIYLPLAADCAEMYQEPAVDQEPEMGTETILVAEDDPSVRNLV
DMVLTKHGYQVILAENGQEVVERFTAHSSDIGLILMDIIMPRKNGIEAFAEIKKLQPEAKVLFTSGYTSDFIQSRGMEDG
VELIMKPVQPAQLLRKVREVLER

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=30.241935483871, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=31.9838056680162, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=405, Percent_Identity=25.4320987654321, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=322, Percent_Identity=26.7080745341615, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=448, Percent_Identity=23.4375, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI87081816, Length=384, Percent_Identity=23.9583333333333, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786599, Length=76, Percent_Identity=43.421052631579, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=113, Percent_Identity=38.0530973451327, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082012, Length=124, Percent_Identity=34.6774193548387, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789809, Length=128, Percent_Identity=34.375, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790346, Length=268, Percent_Identity=26.1194029850746, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73439; Mature: 73439

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILAIDDNHDNLLTLKALLKIFMPEANLITSASAQDGIRRALLEAPDTILLDIQMPVMD
CEEEEEECCCCCCHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCEEEEEEECCCCC
GYEATRRLKGNPSTQHIPIILVTAHRTDPSGKVRGLECGADAFLSKPIDEAELVAQIRAM
CHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHH
VRIKRSEDALRQERDSLEALVQKRTSELLLMNQVLTENLARLAENEARYTRAVRGTTDGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
WDWNVVTGECYFSPRWKELLGFADDELENRVDTFYSRLHPDDMAVAQEALESHLSGKTSL
EECEEEEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCE
DVELRLRNREGGYLRFRVRGQAEWDSLGAAVRLSGALSDVTERQLMEEQLRQSQKMEAVG
EEEEEEECCCCCEEEEEEECCCCHHHCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAGGVAHDFNNILTVIAGYANMLMMDLPALGNEVRLAEQIAIATERAAELTKGLLAFSR
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KQPMAPQKLDLGEIVQRVETFLTRVIGEDIQLKTHLLPDSLPVWVDMGQIEQVLINLAAN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHCC
ARDAMENGGTFTIATGLFEDDSLSAFCGPAGSYAVIIVSDNGKGMPAEISKRIFEPFFTT
HHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
KEVGKGTGLGMAIVYGIVQQHRGYITVDSKPGDGTVFSIYLPLAADCAEMYQEPAVDQEP
HHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCCCCCC
EMGTETILVAEDDPSVRNLVDMVLTKHGYQVILAENGQEVVERFTAHSSDIGLILMDIIM
CCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCCHHHHHHHHC
PRKNGIEAFAEIKKLQPEAKVLFTSGYTSDFIQSRGMEDGVELIMKPVQPAQLLRKVREV
CCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
LER
HCC
>Mature Secondary Structure
MKILAIDDNHDNLLTLKALLKIFMPEANLITSASAQDGIRRALLEAPDTILLDIQMPVMD
CEEEEEECCCCCCHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCEEEEEEECCCCC
GYEATRRLKGNPSTQHIPIILVTAHRTDPSGKVRGLECGADAFLSKPIDEAELVAQIRAM
CHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHH
VRIKRSEDALRQERDSLEALVQKRTSELLLMNQVLTENLARLAENEARYTRAVRGTTDGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
WDWNVVTGECYFSPRWKELLGFADDELENRVDTFYSRLHPDDMAVAQEALESHLSGKTSL
EECEEEEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCE
DVELRLRNREGGYLRFRVRGQAEWDSLGAAVRLSGALSDVTERQLMEEQLRQSQKMEAVG
EEEEEEECCCCCEEEEEEECCCCHHHCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAGGVAHDFNNILTVIAGYANMLMMDLPALGNEVRLAEQIAIATERAAELTKGLLAFSR
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KQPMAPQKLDLGEIVQRVETFLTRVIGEDIQLKTHLLPDSLPVWVDMGQIEQVLINLAAN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHCC
ARDAMENGGTFTIATGLFEDDSLSAFCGPAGSYAVIIVSDNGKGMPAEISKRIFEPFFTT
HHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
KEVGKGTGLGMAIVYGIVQQHRGYITVDSKPGDGTVFSIYLPLAADCAEMYQEPAVDQEP
HHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCCCCCC
EMGTETILVAEDDPSVRNLVDMVLTKHGYQVILAENGQEVVERFTAHSSDIGLILMDIIM
CCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCCHHHHHHHHC
PRKNGIEAFAEIKKLQPEAKVLFTSGYTSDFIQSRGMEDGVELIMKPVQPAQLLRKVREV
CCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
LER
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA