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The map label for this gene is mmlH [H]

Identifier: 197118855

GI number: 197118855

Start: 2870674

End: 2871921

Strand: Direct

Name: mmlH [H]

Synonym: Gbem_2478

Alternate gene names: 197118855

Gene position: 2870674-2871921 (Clockwise)

Preceding gene: 197118854

Following gene: 197118856

Centisome position: 62.2

GC content: 60.74

Gene sequence:

>1248_bases
ATGACATCCAGTGAAGAGAGCACGAAAGTGGCAATTCGGCAGGTATTCGGCTTGCCGGTGATAGTGGCGGCCCTCGGGTA
CTTCGTCGACATATATGACCTGGTACTGTTCAGCATCGTCAGGGTCCCGAGCCTGAAGGGGATCGGGCTCTCCGGGCAAG
AACTGATCGACAAGGGGGTGTTCCTGCTCAACATGCAGATGGCGGGCATGCTGCTGGGCGGCATCCTCTGGGGGGTCCTC
GGCGACAGAAAGGGTCGCCTCAAAATCATGTTCGGCTCTATCTTCATCTACTCTATAGCGAATCTTGCCAACGGCATGGC
CAACTCCATCGAGGCCTACGCCTTTCTCCGTTTCATGGCTGGGGTGGGACTCGCCGGCGAACTCGGCGCCGGCATCACCC
TGGTGAGCGAGGTGCTGCACCGCTCCATCAGGGGTTACGGCACCATGATCGTGGCTACGGTCGGGGTATCGGGAGCCATC
CTCGCCAACATCGTCGCCAAGGAGTTCGATTGGCGCACCGCATTCGTCATCGGGGGCATCCTGGGGCTCATGCTCCTGCT
GCTGCGGGTCGCCGTCGCGGAATCCGGGATGTTCAAGGGGATGGAATCAAAGGAAGTCGCCAAGGGAAACTTCCTCGCCC
TCTTCACCTCGCGCGACCGATTCGGCCGCTTCATGAACTCCATCCTGATCGGCCTCCCCTCCTGGTTCGTGGTGGGGGTC
CTGATCACCTTCTCCCCCGAATTCGCAAGAGCCCTCGCGGTCCAGGGACCGGTTAACGCAGGCAACGCCGTCATGTACTG
CTACATGGGGCTCGTGGCCGGAGATCTCGTGAGCGGGCTCTTGAGCCAGCTGCTGAAAAGCCGCAAGAAAGTGGTGCTCC
TTTTCCTGCTGCTCACGGTCGCGGCAGTGGCCGGATACTTCAGCGCCGCCAAGGTTACAGCCGGCTCCTTCTACATCATC
TGCGGACTCCTTGGCTTCGGTATCGGCTACTGGGCCATCTTCGTCACCGTGGCGGCCGAGCAGTTCGGAACCAACCTGAG
GGCCACCGTCGCCACTACCGTCCCCAACTTCGTGCGCGGCATGACCATCCCCATCACCATGCTGTTCCAGGCGGCGAGAA
AGGTCCTCGGACTGGAAATGGGCGCCTTGGCCGTCGGGGCGCTTTGCCTCGTCATCGCGCTGATAAGCCTCTCCCTGCTA
CAGGAGACTTTCCACAAGGACCTCGACTATTTCGAGGAGTACCTTTGA

Upstream 100 bases:

>100_bases
CTAAGCCAAGACAGGGCAATCTATGAGCAAAGACAGAGCCGCCTGTTTCAGCAAAGCTGATGGGCGGCTTTTTTTACTGT
GACAACAACGGGAGTTGCGG

Downstream 100 bases:

>100_bases
AGCTGTAGTTTAGCTTCCGACGCACGCCCTCACCCCCGCCCCTCTGAGGGCGAGGGGTAACCATAAGGAGACACGAACTA
TGGACCCACTTTCCCTCTTT

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTSSEESTKVAIRQVFGLPVIVAALGYFVDIYDLVLFSIVRVPSLKGIGLSGQELIDKGVFLLNMQMAGMLLGGILWGVL
GDRKGRLKIMFGSIFIYSIANLANGMANSIEAYAFLRFMAGVGLAGELGAGITLVSEVLHRSIRGYGTMIVATVGVSGAI
LANIVAKEFDWRTAFVIGGILGLMLLLLRVAVAESGMFKGMESKEVAKGNFLALFTSRDRFGRFMNSILIGLPSWFVVGV
LITFSPEFARALAVQGPVNAGNAVMYCYMGLVAGDLVSGLLSQLLKSRKKVVLLFLLLTVAAVAGYFSAAKVTAGSFYII
CGLLGFGIGYWAIFVTVAAEQFGTNLRATVATTVPNFVRGMTIPITMLFQAARKVLGLEMGALAVGALCLVIALISLSLL
QETFHKDLDYFEEYL

Sequences:

>Translated_415_residues
MTSSEESTKVAIRQVFGLPVIVAALGYFVDIYDLVLFSIVRVPSLKGIGLSGQELIDKGVFLLNMQMAGMLLGGILWGVL
GDRKGRLKIMFGSIFIYSIANLANGMANSIEAYAFLRFMAGVGLAGELGAGITLVSEVLHRSIRGYGTMIVATVGVSGAI
LANIVAKEFDWRTAFVIGGILGLMLLLLRVAVAESGMFKGMESKEVAKGNFLALFTSRDRFGRFMNSILIGLPSWFVVGV
LITFSPEFARALAVQGPVNAGNAVMYCYMGLVAGDLVSGLLSQLLKSRKKVVLLFLLLTVAAVAGYFSAAKVTAGSFYII
CGLLGFGIGYWAIFVTVAAEQFGTNLRATVATTVPNFVRGMTIPITMLFQAARKVLGLEMGALAVGALCLVIALISLSLL
QETFHKDLDYFEEYL
>Mature_414_residues
TSSEESTKVAIRQVFGLPVIVAALGYFVDIYDLVLFSIVRVPSLKGIGLSGQELIDKGVFLLNMQMAGMLLGGILWGVLG
DRKGRLKIMFGSIFIYSIANLANGMANSIEAYAFLRFMAGVGLAGELGAGITLVSEVLHRSIRGYGTMIVATVGVSGAIL
ANIVAKEFDWRTAFVIGGILGLMLLLLRVAVAESGMFKGMESKEVAKGNFLALFTSRDRFGRFMNSILIGLPSWFVVGVL
ITFSPEFARALAVQGPVNAGNAVMYCYMGLVAGDLVSGLLSQLLKSRKKVVLLFLLLTVAAVAGYFSAAKVTAGSFYIIC
GLLGFGIGYWAIFVTVAAEQFGTNLRATVATTVPNFVRGMTIPITMLFQAARKVLGLEMGALAVGALCLVIALISLSLLQ
ETFHKDLDYFEEYL

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=148, Percent_Identity=30.4054054054054, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081723, Length=244, Percent_Identity=31.1475409836066, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87082231, Length=181, Percent_Identity=29.2817679558011, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44394; Mature: 44262

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSEESTKVAIRQVFGLPVIVAALGYFVDIYDLVLFSIVRVPSLKGIGLSGQELIDKGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCH
FLLNMQMAGMLLGGILWGVLGDRKGRLKIMFGSIFIYSIANLANGMANSIEAYAFLRFMA
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGLAGELGAGITLVSEVLHRSIRGYGTMIVATVGVSGAILANIVAKEFDWRTAFVIGGI
CCCCCHHHCCHHHHHHHHHHHHHHCCCHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
LGLMLLLLRVAVAESGMFKGMESKEVAKGNFLALFTSRDRFGRFMNSILIGLPSWFVVGV
HHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEEEECHHHHHHHHHHHHHHCHHHHHHHH
LITFSPEFARALAVQGPVNAGNAVMYCYMGLVAGDLVSGLLSQLLKSRKKVVLLFLLLTV
HHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVAGYFSAAKVTAGSFYIICGLLGFGIGYWAIFVTVAAEQFGTNLRATVATTVPNFVRG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
MTIPITMLFQAARKVLGLEMGALAVGALCLVIALISLSLLQETFHKDLDYFEEYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSSEESTKVAIRQVFGLPVIVAALGYFVDIYDLVLFSIVRVPSLKGIGLSGQELIDKGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCH
FLLNMQMAGMLLGGILWGVLGDRKGRLKIMFGSIFIYSIANLANGMANSIEAYAFLRFMA
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGLAGELGAGITLVSEVLHRSIRGYGTMIVATVGVSGAILANIVAKEFDWRTAFVIGGI
CCCCCHHHCCHHHHHHHHHHHHHHCCCHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
LGLMLLLLRVAVAESGMFKGMESKEVAKGNFLALFTSRDRFGRFMNSILIGLPSWFVVGV
HHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEEEECHHHHHHHHHHHHHHCHHHHHHHH
LITFSPEFARALAVQGPVNAGNAVMYCYMGLVAGDLVSGLLSQLLKSRKKVVLLFLLLTV
HHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVAGYFSAAKVTAGSFYIICGLLGFGIGYWAIFVTVAAEQFGTNLRATVATTVPNFVRG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
MTIPITMLFQAARKVLGLEMGALAVGALCLVIALISLSLLQETFHKDLDYFEEYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]