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The map label for this gene is rodA [H]

Identifier: 197118836

GI number: 197118836

Start: 2848097

End: 2849197

Strand: Reverse

Name: rodA [H]

Synonym: Gbem_2459

Alternate gene names: 197118836

Gene position: 2849197-2848097 (Counterclockwise)

Preceding gene: 197118837

Following gene: 197118835

Centisome position: 61.74

GC content: 61.04

Gene sequence:

>1101_bases
ATGTTCGATCGACGGCTATTCACCAACTTCGACTGGACCCTCTTGGGGGTGGTGCTGCTCATCACGGCCTTCGGGGTCGT
CAACATATACAGCGCCTCGTCCTCGTACCGGGACATAGGCACCCCCTACTACCTGAAGCAGCTCTACTGGATCTTCGCGG
GTCTCATCCTCTGCCTCACGGTCTGCAGCCTCGACTACCATATGCTGGAGGACTTCGCCTACTGGCTCTACGGCGGCGTC
CTGGTCCTTCTGGTGCTGGTGCTCGTGGCTGGCAAGACCAGCATGGGGGCGACCCGCTGGATCCACCTCGGCTTCTTCAA
CATGCAGCCCTCCGAGCCTATGAAGATCGTCATCATCATGACCTTCGCCAGGTTCTTCAGCCGCTACCCGATCTTCAAGG
GGCTCACCCTCAAGGACCTGGTCTACCCGCTGCTCATCCTCGGGGCGCCGGCCTTGCTCATCATGAAGCAGCCCGACCTC
GGGACCGCGGTGCTGGTGAGCCTGATCGGCGGGACCATGCTCCTTTTCGTAGGGGTGCGCTGGTCCGCGCTCGCCTCCCT
CTTCGCCGCCGCACTTCCCATCGTCTACGGCGCCTGGACCTTCGGGCTGCACGACTACCAGAAGAATAGGATCTACAACT
TCCTGAACCCCGACCTCGACCCTTTGGGGAGCGGCTACCACATCATCCAGAGCAAGATCGCCGTAGGCTCCGGGGCCACC
TTCGGCAAAGGGTTCATGCAGGGGACCCAGTCCCAGCTCCGCTTTCTCCCCGAGCAGCATACCGACTTCGCCTTCTCCGT
CTTCGCCGAGGAGTGGGGGTTTGCCGGCTGCCTGTTGATGTTGACCCTCTACCTCTTCCTCATCCTTTGGGGGCTCTCCA
TCGCCAAACGCTGCAACGACCGTTTCGGTTCCCTTCTGGCCGTCGGCGTCTCCGCGATGCTCTTTTGGCATATCGTCATC
AACATGGGGATGGTGATCGGCCTGCTCCCCGTGGTCGGTGTCCCGCTCCCCTTTTTCTCCTACGGCGGCACCTCCATGGT
CACCTCCATGGTCGGCGTCGGGATACTTTTGAACATCAGCATGCGGCGCTTCATGTTCTAA

Upstream 100 bases:

>100_bases
CGCCCCAGGCTCCCCCGGCTACTCCGGCAACCGAGAACAGGTCCGGCAACACCGACAGATAGCTCCGATTTCACCATCGG
ACCAGGGTAAAGGAACGCAG

Downstream 100 bases:

>100_bases
GCCCCCTGGAGGCTCGGGGATTTCGTCGTCAATTGTCAATCGTCAATTGTCAATTGGTTTAGAGGAGCTGCAGCATGCGC
ATCACCCTGGTCGAGCCCTA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MFDRRLFTNFDWTLLGVVLLITAFGVVNIYSASSSYRDIGTPYYLKQLYWIFAGLILCLTVCSLDYHMLEDFAYWLYGGV
LVLLVLVLVAGKTSMGATRWIHLGFFNMQPSEPMKIVIIMTFARFFSRYPIFKGLTLKDLVYPLLILGAPALLIMKQPDL
GTAVLVSLIGGTMLLFVGVRWSALASLFAAALPIVYGAWTFGLHDYQKNRIYNFLNPDLDPLGSGYHIIQSKIAVGSGAT
FGKGFMQGTQSQLRFLPEQHTDFAFSVFAEEWGFAGCLLMLTLYLFLILWGLSIAKRCNDRFGSLLAVGVSAMLFWHIVI
NMGMVIGLLPVVGVPLPFFSYGGTSMVTSMVGVGILLNISMRRFMF

Sequences:

>Translated_366_residues
MFDRRLFTNFDWTLLGVVLLITAFGVVNIYSASSSYRDIGTPYYLKQLYWIFAGLILCLTVCSLDYHMLEDFAYWLYGGV
LVLLVLVLVAGKTSMGATRWIHLGFFNMQPSEPMKIVIIMTFARFFSRYPIFKGLTLKDLVYPLLILGAPALLIMKQPDL
GTAVLVSLIGGTMLLFVGVRWSALASLFAAALPIVYGAWTFGLHDYQKNRIYNFLNPDLDPLGSGYHIIQSKIAVGSGAT
FGKGFMQGTQSQLRFLPEQHTDFAFSVFAEEWGFAGCLLMLTLYLFLILWGLSIAKRCNDRFGSLLAVGVSAMLFWHIVI
NMGMVIGLLPVVGVPLPFFSYGGTSMVTSMVGVGILLNISMRRFMF
>Mature_366_residues
MFDRRLFTNFDWTLLGVVLLITAFGVVNIYSASSSYRDIGTPYYLKQLYWIFAGLILCLTVCSLDYHMLEDFAYWLYGGV
LVLLVLVLVAGKTSMGATRWIHLGFFNMQPSEPMKIVIIMTFARFFSRYPIFKGLTLKDLVYPLLILGAPALLIMKQPDL
GTAVLVSLIGGTMLLFVGVRWSALASLFAAALPIVYGAWTFGLHDYQKNRIYNFLNPDLDPLGSGYHIIQSKIAVGSGAT
FGKGFMQGTQSQLRFLPEQHTDFAFSVFAEEWGFAGCLLMLTLYLFLILWGLSIAKRCNDRFGSLLAVGVSAMLFWHIVI
NMGMVIGLLPVVGVPLPFFSYGGTSMVTSMVGVGILLNISMRRFMF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=345, Percent_Identity=44.3478260869565, Blast_Score=244, Evalue=5e-66,
Organism=Escherichia coli, GI1786277, Length=363, Percent_Identity=30.5785123966942, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40801; Mature: 40801

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRRLFTNFDWTLLGVVLLITAFGVVNIYSASSSYRDIGTPYYLKQLYWIFAGLILCLT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VCSLDYHMLEDFAYWLYGGVLVLLVLVLVAGKTSMGATRWIHLGFFNMQPSEPMKIVIIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEHHHH
TFARFFSRYPIFKGLTLKDLVYPLLILGAPALLIMKQPDLGTAVLVSLIGGTMLLFVGVR
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
WSALASLFAAALPIVYGAWTFGLHDYQKNRIYNFLNPDLDPLGSGYHIIQSKIAVGSGAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
FGKGFMQGTQSQLRFLPEQHTDFAFSVFAEEWGFAGCLLMLTLYLFLILWGLSIAKRCND
HHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGSLLAVGVSAMLFWHIVINMGMVIGLLPVVGVPLPFFSYGGTSMVTSMVGVGILLNIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHH
MRRFMF
HHHHCC
>Mature Secondary Structure
MFDRRLFTNFDWTLLGVVLLITAFGVVNIYSASSSYRDIGTPYYLKQLYWIFAGLILCLT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VCSLDYHMLEDFAYWLYGGVLVLLVLVLVAGKTSMGATRWIHLGFFNMQPSEPMKIVIIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEHHHH
TFARFFSRYPIFKGLTLKDLVYPLLILGAPALLIMKQPDLGTAVLVSLIGGTMLLFVGVR
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
WSALASLFAAALPIVYGAWTFGLHDYQKNRIYNFLNPDLDPLGSGYHIIQSKIAVGSGAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
FGKGFMQGTQSQLRFLPEQHTDFAFSVFAEEWGFAGCLLMLTLYLFLILWGLSIAKRCND
HHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGSLLAVGVSAMLFWHIVINMGMVIGLLPVVGVPLPFFSYGGTSMVTSMVGVGILLNIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHH
MRRFMF
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]