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The map label for this gene is kamA [H]

Identifier: 197118777

GI number: 197118777

Start: 2777921

End: 2778955

Strand: Reverse

Name: kamA [H]

Synonym: Gbem_2398

Alternate gene names: 197118777

Gene position: 2778955-2777921 (Counterclockwise)

Preceding gene: 197118778

Following gene: 197118776

Centisome position: 60.21

GC content: 64.64

Gene sequence:

>1035_bases
ATGGAAGCGTGGGAGAAAAGCCTGAAAAACTGCATCACCAGCCCGGAGGAGCTTTCCGGGCTTTTTCGTCTGCAGGGGGG
CGCGTTTTCGCCGGTGGTCGAGCGCTACCCCATGCGGATCACGCCCTACTACCTCGGACTGATCGAGGAGCCGGGCGATC
CCATCTGGCGCCAGTGCGTCCCCGACCCTGCAGAGCTTGACGACCTGACCCAGTCCCCCGATCCCCTGGACGAGGAGCGG
CTTTCCCCGGTCCCCGGGTTGATCCACCGCTACCCGGACCGGGTCGTCTGGATCGTCTCCTCTGCCTGCGCCGTCTACTG
CCGCTTCTGCATGAGGAAAAGAGGGGTGGGGTGCGCCAGCATGGCGCCGGCCAAGGTTGACGACGCCATCGCTTACATTG
CCGGCGACCCGCGGATCCGCGACGTCGTCCTCTCCGGCGGCGATCCGCTGCTCTTGCCGGATGACCGTCTCGCCGCGATA
CTCTCAGCGCTTTCCCGCATACCGCACGTCGAGATCGTGAGGATCGGGACGCGGGCCCCGGTGACCCTTCCGGAAAGGAT
CACCCCCGGGCTCACGCGCCTTTTGAAGCGCAGCCATCCTGTCTACGTCAACACCCACTTCAACCATCCCCGGGAGATAA
CCCCGCAATCGGCCAAGGCCTGTGCCAGGCTCGCCGATGCCGGGGTGCAGCTGGGGAACCAGACCGTGCTCCTCAAGGGG
GTGAACGACGACCCCCAGACGATGCTGAGCCTGATGCGGCGTCTGCTCGCCATCCGGGTGCGTCCTTACTACATACATCA
AATGGACCTGGTACAGGGGACCGCCCACTTCAGGACCCGCGTGGGGCAGGGGATCTCCGTGATGCAGGCGCTGCGCGGCC
ACACCTCCGGGCTTGCCGTTCCGCATTACGTCATCGACCTCCCTGGCGGCAAAGGAAAGGTCGATGTCCTTTCCGGTCGC
CCTGGCAGTGGCGGCCGGACTCTGCTTTTCACCAACTACCTGGGAGAAGAGATCGAGTACCCAGAACCGGATTAA

Upstream 100 bases:

>100_bases
ACCCCTCCGCGGCTCAGCGGATCGCCCGGGAGATGGAGCAGTACCTGGTTGACCACAAGATAGAATCTGTCTCCTCGCTG
ATCGGTGCCCTAGAGCTCTG

Downstream 100 bases:

>100_bases
CTGTTACTGCCGCGTCCGTTTTCCTTTCCATATTTGCAAACACGCAGGATCTTACTCCGAATATTAGCAAATCTCCCCCC
AACGCTGAAGTAGTCGCTGC

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MEAWEKSLKNCITSPEELSGLFRLQGGAFSPVVERYPMRITPYYLGLIEEPGDPIWRQCVPDPAELDDLTQSPDPLDEER
LSPVPGLIHRYPDRVVWIVSSACAVYCRFCMRKRGVGCASMAPAKVDDAIAYIAGDPRIRDVVLSGGDPLLLPDDRLAAI
LSALSRIPHVEIVRIGTRAPVTLPERITPGLTRLLKRSHPVYVNTHFNHPREITPQSAKACARLADAGVQLGNQTVLLKG
VNDDPQTMLSLMRRLLAIRVRPYYIHQMDLVQGTAHFRTRVGQGISVMQALRGHTSGLAVPHYVIDLPGGKGKVDVLSGR
PGSGGRTLLFTNYLGEEIEYPEPD

Sequences:

>Translated_344_residues
MEAWEKSLKNCITSPEELSGLFRLQGGAFSPVVERYPMRITPYYLGLIEEPGDPIWRQCVPDPAELDDLTQSPDPLDEER
LSPVPGLIHRYPDRVVWIVSSACAVYCRFCMRKRGVGCASMAPAKVDDAIAYIAGDPRIRDVVLSGGDPLLLPDDRLAAI
LSALSRIPHVEIVRIGTRAPVTLPERITPGLTRLLKRSHPVYVNTHFNHPREITPQSAKACARLADAGVQLGNQTVLLKG
VNDDPQTMLSLMRRLLAIRVRPYYIHQMDLVQGTAHFRTRVGQGISVMQALRGHTSGLAVPHYVIDLPGGKGKVDVLSGR
PGSGGRTLLFTNYLGEEIEYPEPD
>Mature_344_residues
MEAWEKSLKNCITSPEELSGLFRLQGGAFSPVVERYPMRITPYYLGLIEEPGDPIWRQCVPDPAELDDLTQSPDPLDEER
LSPVPGLIHRYPDRVVWIVSSACAVYCRFCMRKRGVGCASMAPAKVDDAIAYIAGDPRIRDVVLSGGDPLLLPDDRLAAI
LSALSRIPHVEIVRIGTRAPVTLPERITPGLTRLLKRSHPVYVNTHFNHPREITPQSAKACARLADAGVQLGNQTVLLKG
VNDDPQTMLSLMRRLLAIRVRPYYIHQMDLVQGTAHFRTRVGQGISVMQALRGHTSGLAVPHYVIDLPGGKGKVDVLSGR
PGSGGRTLLFTNYLGEEIEYPEPD

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=324, Percent_Identity=33.3333333333333, Blast_Score=182, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 37951; Mature: 37951

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAWEKSLKNCITSPEELSGLFRLQGGAFSPVVERYPMRITPYYLGLIEEPGDPIWRQCV
CCHHHHHHHHHCCCHHHHHHHHEECCCCCCHHHHHCCCEECHHEEEEECCCCCHHHHHCC
PDPAELDDLTQSPDPLDEERLSPVPGLIHRYPDRVVWIVSSACAVYCRFCMRKRGVGCAS
CCCHHHHHHCCCCCCCCHHHCCCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCC
MAPAKVDDAIAYIAGDPRIRDVVLSGGDPLLLPDDRLAAILSALSRIPHVEIVRIGTRAP
CCCCCHHHCEEEEECCCCEEEEEECCCCEEECCCHHHHHHHHHHHHCCCEEEEEECCCCC
VTLPERITPGLTRLLKRSHPVYVNTHFNHPREITPQSAKACARLADAGVQLGNQTVLLKG
CCCCHHCCHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
VNDDPQTMLSLMRRLLAIRVRPYYIHQMDLVQGTAHFRTRVGQGISVMQALRGHTSGLAV
CCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
PHYVIDLPGGKGKVDVLSGRPGSGGRTLLFTNYLGEEIEYPEPD
CEEEEECCCCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MEAWEKSLKNCITSPEELSGLFRLQGGAFSPVVERYPMRITPYYLGLIEEPGDPIWRQCV
CCHHHHHHHHHCCCHHHHHHHHEECCCCCCHHHHHCCCEECHHEEEEECCCCCHHHHHCC
PDPAELDDLTQSPDPLDEERLSPVPGLIHRYPDRVVWIVSSACAVYCRFCMRKRGVGCAS
CCCHHHHHHCCCCCCCCHHHCCCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCC
MAPAKVDDAIAYIAGDPRIRDVVLSGGDPLLLPDDRLAAILSALSRIPHVEIVRIGTRAP
CCCCCHHHCEEEEECCCCEEEEEECCCCEEECCCHHHHHHHHHHHHCCCEEEEEECCCCC
VTLPERITPGLTRLLKRSHPVYVNTHFNHPREITPQSAKACARLADAGVQLGNQTVLLKG
CCCCHHCCHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
VNDDPQTMLSLMRRLLAIRVRPYYIHQMDLVQGTAHFRTRVGQGISVMQALRGHTSGLAV
CCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
PHYVIDLPGGKGKVDVLSGRPGSGGRTLLFTNYLGEEIEYPEPD
CEEEEECCCCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]