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The map label for this gene is purQ [H]

Identifier: 197118711

GI number: 197118711

Start: 2702365

End: 2703189

Strand: Reverse

Name: purQ [H]

Synonym: Gbem_2330

Alternate gene names: 197118711

Gene position: 2703189-2702365 (Counterclockwise)

Preceding gene: 197118712

Following gene: 197118710

Centisome position: 58.57

GC content: 62.67

Gene sequence:

>825_bases
ATGACAAAGGCTAAAGCGCTAGTCATAACAGGCAACGGCACCAACTGCGAAATGGAGGCGGCCCACGCCTGCCGCCTGGG
CGGCTTCGACGAGGCGCGCATCGCCCATATATCGGAACTTATGTCCGGCGAAGTGAGCCTGGACGATTACCACTTCCTCA
ACTTGACCGGCGGCTTCCTCGACGGCGACGACCTGGGGAGCGCCAAAGCGCAGGCGAACCGGCTGCGCTACGCAGCGGTA
GAAGGGAAGGGGGAGCTCCTGGTGGACCAGATCTCCCGCTTCATCGCCGACGGCAAGCTTATCTTGGGCGTCTGCAACGG
GTTCCAGCTCCTGGTGAAGATGGGGATGCTCCCGGCTCTGGGGGGCAATTATCTGAATCAGACCGCGACGCTGACCTACA
ACGCCAACGGCCGTTTCCAGGACCGCTGGTGCTACCTGAAGTGCGACGCGGCTTCCCCGTCGTTGTACACCCGCGGCATC
GAGGGCGGGGTCTACCTTCCCGTGCGCCACGGCGAAGGTAAGTTCCTGGTGGACGACGCCAATACGCTCGAAGCGATCGA
GACGAAGCACCTCACCTGCCTCAAGTACTCCGACAAGCACTACGCGGCACCGACCATGGAGTTCCCCGAGAACCCCAACG
GCTCCGTCAACGCCATCGCCGGCATCTGCGACGAGACCGGCAGGGTCATGGGGCTCATGCCGCACCCCGAGGCGTTCGTG
CACCGGACCCAGCACCCGCGCTGGACTAGAGAGGACCTGCCGGAAGAGGGCGAGGGGCTGATTTTCTTCAAGAACGCGGC
TAAGTACGTGAAGGAAAACTTCTAG

Upstream 100 bases:

>100_bases
GAAGGATCTGTAAAATCTTTATATGCAGAAAAAATGCGGGTTATGCCATAATGAACGGCGTTGCTTCCCGCTACCAATCT
TTTCATAGAGGACTTATTTG

Downstream 100 bases:

>100_bases
ATAAGTCTTCCCCCCACCGAAAGGGGACTGGCTCCGCCAGGTGCCTGTCTCCCTTCGGGGATGGACTGATCTCCCCACCG
AGGGGAAGAATGGTGGACGA

Product: phosphoribosylformylglycinamidine synthase, PurQ domain-containing protein

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTKAKALVITGNGTNCEMEAAHACRLGGFDEARIAHISELMSGEVSLDDYHFLNLTGGFLDGDDLGSAKAQANRLRYAAV
EGKGELLVDQISRFIADGKLILGVCNGFQLLVKMGMLPALGGNYLNQTATLTYNANGRFQDRWCYLKCDAASPSLYTRGI
EGGVYLPVRHGEGKFLVDDANTLEAIETKHLTCLKYSDKHYAAPTMEFPENPNGSVNAIAGICDETGRVMGLMPHPEAFV
HRTQHPRWTREDLPEEGEGLIFFKNAAKYVKENF

Sequences:

>Translated_274_residues
MTKAKALVITGNGTNCEMEAAHACRLGGFDEARIAHISELMSGEVSLDDYHFLNLTGGFLDGDDLGSAKAQANRLRYAAV
EGKGELLVDQISRFIADGKLILGVCNGFQLLVKMGMLPALGGNYLNQTATLTYNANGRFQDRWCYLKCDAASPSLYTRGI
EGGVYLPVRHGEGKFLVDDANTLEAIETKHLTCLKYSDKHYAAPTMEFPENPNGSVNAIAGICDETGRVMGLMPHPEAFV
HRTQHPRWTREDLPEEGEGLIFFKNAAKYVKENF
>Mature_273_residues
TKAKALVITGNGTNCEMEAAHACRLGGFDEARIAHISELMSGEVSLDDYHFLNLTGGFLDGDDLGSAKAQANRLRYAAVE
GKGELLVDQISRFIADGKLILGVCNGFQLLVKMGMLPALGGNYLNQTATLTYNANGRFQDRWCYLKCDAASPSLYTRGIE
GGVYLPVRHGEGKFLVDDANTLEAIETKHLTCLKYSDKHYAAPTMEFPENPNGSVNAIAGICDETGRVMGLMPHPEAFVH
RTQHPRWTREDLPEEGEGLIFFKNAAKYVKENF

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=288, Percent_Identity=31.9444444444444, Blast_Score=114, Evalue=9e-26,
Organism=Escherichia coli, GI48994899, Length=270, Percent_Identity=34.8148148148148, Blast_Score=138, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17553022, Length=246, Percent_Identity=27.6422764227642, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321498, Length=281, Percent_Identity=30.9608540925267, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24582111, Length=276, Percent_Identity=31.1594202898551, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24582109, Length=276, Percent_Identity=31.1594202898551, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI17137292, Length=276, Percent_Identity=31.1594202898551, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 30068; Mature: 29937

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAKALVITGNGTNCEMEAAHACRLGGFDEARIAHISELMSGEVSLDDYHFLNLTGGFL
CCCCEEEEEECCCCCCEEHHHHEHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
DGDDLGSAKAQANRLRYAAVEGKGELLVDQISRFIADGKLILGVCNGFQLLVKMGMLPAL
CCCCCCCHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCC
GGNYLNQTATLTYNANGRFQDRWCYLKCDAASPSLYTRGIEGGVYLPVRHGEGKFLVDDA
CCCCCCCEEEEEECCCCCEECEEEEEEECCCCCCCEEECCCCCEEEEEEECCCCEEEECC
NTLEAIETKHLTCLKYSDKHYAAPTMEFPENPNGSVNAIAGICDETGRVMGLMPHPEAFV
CHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCHHHH
HRTQHPRWTREDLPEEGEGLIFFKNAAKYVKENF
CCCCCCCCCHHCCCCCCCEEEEECCHHHHHHCCC
>Mature Secondary Structure 
TKAKALVITGNGTNCEMEAAHACRLGGFDEARIAHISELMSGEVSLDDYHFLNLTGGFL
CCCEEEEEECCCCCCEEHHHHEHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
DGDDLGSAKAQANRLRYAAVEGKGELLVDQISRFIADGKLILGVCNGFQLLVKMGMLPAL
CCCCCCCHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCC
GGNYLNQTATLTYNANGRFQDRWCYLKCDAASPSLYTRGIEGGVYLPVRHGEGKFLVDDA
CCCCCCCEEEEEECCCCCEECEEEEEEECCCCCCCEEECCCCCEEEEEEECCCCEEEECC
NTLEAIETKHLTCLKYSDKHYAAPTMEFPENPNGSVNAIAGICDETGRVMGLMPHPEAFV
CHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCHHHH
HRTQHPRWTREDLPEEGEGLIFFKNAAKYVKENF
CCCCCCCCCHHCCCCCCCEEEEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA