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The map label for this gene is sbcD [H]

Identifier: 197118683

GI number: 197118683

Start: 2675379

End: 2676644

Strand: Reverse

Name: sbcD [H]

Synonym: Gbem_2302

Alternate gene names: 197118683

Gene position: 2676644-2675379 (Counterclockwise)

Preceding gene: 197118684

Following gene: 197118682

Centisome position: 58.0

GC content: 62.72

Gene sequence:

>1266_bases
ATGCCCGTCAGATTCATCCACACCTCAGACATACACCTGGGAAAAACCTACCGCTGCCTGGGCGGCGACGCCGAGCGCTA
TCAGGACTTTTTCACCACCTTCGCAAACATCATCGCCGACGCCGTCAAGGAGCAGGTCGACTTCGTCCTGATCGGCGGCG
ACCTCTTCCATACCGGACAAATCCTCCCTAAGACTTTCGCCAAAACCATCGAGATCCTGCAGCCGTTGAAAGACGCGGGG
ATCCCCTGTCTAGCCGTCGAAGGAAACCACGACTGGATCCATCGCCGCGACAGCGTCTCGTGGATGGAGGCGCTTTCCCA
ACTCGGGTACATCCGCCTGCTGCGCCCGTCGCGTACCGGCGAGGGTGACTACCTCTTCGAGCCCTTCGATCTGGAGCAGG
GAGCGGGGGGGCATATTGAAATAGGCGGGGTGAATATCTACGGCCTCGGGTATATCGGCTCCCAGGCGGCCAACCACGTG
GCGCGCATCTGCGAGGCGGTCGACACCCGTCGCAACATCCTACTCTTCCACGTCGGCGTCTGGAGCTACTCTCCCGTGGA
GATCGGGAACATCCGTCCCGAAGAGGCGCTCCCTTTGTCGGAGTGCTTCGACTACGTGGCACTGGGGCACGGCCACAAAC
CTTACGTCGTCAGTACCCCCGACGGGCGTCCCTATGCCTTCAACCCCGGTTCGCCCGACTGCGTCAACTTCGGCGAGGAG
CGCTACGACAAGGGGTACTACCTTGTCTCGTTGGAAAACGATGGGGAGGTCCGCCACGAATTCCGGCGCTGTTCCCCCCG
CCCGATGCTGGTTCTCACGGTCAATCTGGAAGGTGCCAACAACGCCGACGAGGCGCTGCAGCGGTTCGCCGCCGGGGTCG
CCGAGAAGCTCGCCGGCGGTTCAGACCCGCGCTCGCCGCTGATCGAGGTTCGGCTCTGCGGCAAGGTCGGTTTCCACCCC
TTCGAGCTCAGCCGCGACCGCCTGCGCCTGGCCCTCTTCGAGGTCTGCCAACCGCTGCACCTGGAGATAAAGAACCACCT
CTCCCAGGTCTCGGGGGGGGGAGGGGAGGAGAAGGTCAAGAAGAGCCTCGCCGAGATCGAGCGGGATGTGTTGGCTGAAC
TGGTAGGGGCTAACAGCCAGTATCAGGGTAGGGAAGAGGAGCTGGTGCGTCTTTCCCTGGCTCTTCGCGACCTGGTGCTC
AAGGGGGAGGTAGAGGGTGAGGAACTGCTGGCCCTGCTTCCGTCTGGAGGTGCCGGATGCGCATAA

Upstream 100 bases:

>100_bases
CTTGAGGCGGCAAGCGGCGGTATACCTGTTCAATTCAAAAAGGGGGACAGGCTACTTTTTCAAATCAAAAAGTAGCCTGT
CCCCTTTTCCCGGAGCCGTC

Downstream 100 bases:

>100_bases
TCTCGGTCCAGCTGAAGAACATCAAGTCGCACCGCGACAAAGAGATTGCCTTCTCCCCCGGTATCAACGTCCTCTCCGGC
GCCAACGGTTCGGGCAAAAG

Product: DNA repair exonuclease SbcCD subunit D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MPVRFIHTSDIHLGKTYRCLGGDAERYQDFFTTFANIIADAVKEQVDFVLIGGDLFHTGQILPKTFAKTIEILQPLKDAG
IPCLAVEGNHDWIHRRDSVSWMEALSQLGYIRLLRPSRTGEGDYLFEPFDLEQGAGGHIEIGGVNIYGLGYIGSQAANHV
ARICEAVDTRRNILLFHVGVWSYSPVEIGNIRPEEALPLSECFDYVALGHGHKPYVVSTPDGRPYAFNPGSPDCVNFGEE
RYDKGYYLVSLENDGEVRHEFRRCSPRPMLVLTVNLEGANNADEALQRFAAGVAEKLAGGSDPRSPLIEVRLCGKVGFHP
FELSRDRLRLALFEVCQPLHLEIKNHLSQVSGGGGEEKVKKSLAEIERDVLAELVGANSQYQGREEELVRLSLALRDLVL
KGEVEGEELLALLPSGGAGCA

Sequences:

>Translated_421_residues
MPVRFIHTSDIHLGKTYRCLGGDAERYQDFFTTFANIIADAVKEQVDFVLIGGDLFHTGQILPKTFAKTIEILQPLKDAG
IPCLAVEGNHDWIHRRDSVSWMEALSQLGYIRLLRPSRTGEGDYLFEPFDLEQGAGGHIEIGGVNIYGLGYIGSQAANHV
ARICEAVDTRRNILLFHVGVWSYSPVEIGNIRPEEALPLSECFDYVALGHGHKPYVVSTPDGRPYAFNPGSPDCVNFGEE
RYDKGYYLVSLENDGEVRHEFRRCSPRPMLVLTVNLEGANNADEALQRFAAGVAEKLAGGSDPRSPLIEVRLCGKVGFHP
FELSRDRLRLALFEVCQPLHLEIKNHLSQVSGGGGEEKVKKSLAEIERDVLAELVGANSQYQGREEELVRLSLALRDLVL
KGEVEGEELLALLPSGGAGCA
>Mature_420_residues
PVRFIHTSDIHLGKTYRCLGGDAERYQDFFTTFANIIADAVKEQVDFVLIGGDLFHTGQILPKTFAKTIEILQPLKDAGI
PCLAVEGNHDWIHRRDSVSWMEALSQLGYIRLLRPSRTGEGDYLFEPFDLEQGAGGHIEIGGVNIYGLGYIGSQAANHVA
RICEAVDTRRNILLFHVGVWSYSPVEIGNIRPEEALPLSECFDYVALGHGHKPYVVSTPDGRPYAFNPGSPDCVNFGEER
YDKGYYLVSLENDGEVRHEFRRCSPRPMLVLTVNLEGANNADEALQRFAAGVAEKLAGGSDPRSPLIEVRLCGKVGFHPF
ELSRDRLRLALFEVCQPLHLEIKNHLSQVSGGGGEEKVKKSLAEIERDVLAELVGANSQYQGREEELVRLSLALRDLVLK
GEVEGEELLALLPSGGAGCA

Specific function: Involved in DNA double-strand break repair (DSBR). The rad50/mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity [H]

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MRE11/RAD32 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003701
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 46439; Mature: 46308

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRFIHTSDIHLGKTYRCLGGDAERYQDFFTTFANIIADAVKEQVDFVLIGGDLFHTGQ
CCEEEEEECCEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEECCCC
ILPKTFAKTIEILQPLKDAGIPCLAVEGNHDWIHRRDSVSWMEALSQLGYIRLLRPSRTG
CCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHCCCCCHHHHHHHHHCCEEEEECCCCCC
EGDYLFEPFDLEQGAGGHIEIGGVNIYGLGYIGSQAANHVARICEAVDTRRNILLFHVGV
CCCEEECCCCCCCCCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEC
WSYSPVEIGNIRPEEALPLSECFDYVALGHGHKPYVVSTPDGRPYAFNPGSPDCVNFGEE
CCCCCEEECCCCCHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCHHHCCCHH
RYDKGYYLVSLENDGEVRHEFRRCSPRPMLVLTVNLEGANNADEALQRFAAGVAEKLAGG
HCCCCEEEEEECCCCHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCC
SDPRSPLIEVRLCGKVGFHPFELSRDRLRLALFEVCQPLHLEIKNHLSQVSGGGGEEKVK
CCCCCCEEEEEEECCCCCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHH
KSLAEIERDVLAELVGANSQYQGREEELVRLSLALRDLVLKGEVEGEELLALLPSGGAGC
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
A
C
>Mature Secondary Structure 
PVRFIHTSDIHLGKTYRCLGGDAERYQDFFTTFANIIADAVKEQVDFVLIGGDLFHTGQ
CEEEEEECCEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEECCCC
ILPKTFAKTIEILQPLKDAGIPCLAVEGNHDWIHRRDSVSWMEALSQLGYIRLLRPSRTG
CCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHCCCCCHHHHHHHHHCCEEEEECCCCCC
EGDYLFEPFDLEQGAGGHIEIGGVNIYGLGYIGSQAANHVARICEAVDTRRNILLFHVGV
CCCEEECCCCCCCCCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEC
WSYSPVEIGNIRPEEALPLSECFDYVALGHGHKPYVVSTPDGRPYAFNPGSPDCVNFGEE
CCCCCEEECCCCCHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCHHHCCCHH
RYDKGYYLVSLENDGEVRHEFRRCSPRPMLVLTVNLEGANNADEALQRFAAGVAEKLAGG
HCCCCEEEEEECCCCHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCC
SDPRSPLIEVRLCGKVGFHPFELSRDRLRLALFEVCQPLHLEIKNHLSQVSGGGGEEKVK
CCCCCCEEEEEEECCCCCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHH
KSLAEIERDVLAELVGANSQYQGREEELVRLSLALRDLVLKGEVEGEELLALLPSGGAGC
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]