Click here to switch to the map view.

The map label for this gene is dhmA2 [H]

Identifier: 197118483

GI number: 197118483

Start: 2426474

End: 2427376

Strand: Reverse

Name: dhmA2 [H]

Synonym: Gbem_2101

Alternate gene names: 197118483

Gene position: 2427376-2426474 (Counterclockwise)

Preceding gene: 197118484

Following gene: 197118482

Centisome position: 52.6

GC content: 64.23

Gene sequence:

>903_bases
ATGACTCTTGATATAAAAGCGCACTACCCCTTCACCGGACGCACGCTGGACCTGGGCGGCCTCTCCTACCACTACCTCGA
CGAGGGCGCGGGCGAGCCTGTGGTCATGGTGCACGGGAACCCTTCCTGGTCCTTCTACTACCGAAACCTGGTGCTGGCGC
TGCGCGACAATTTCCGCTGCATCGTTCCGGACCACATCGGCTGCGGCTTCTCGGACAAGCCCGGCGACGACCGCTACGAC
TACACGCTCGCGCGCCGCATCGACGACCTGGAGCGCCTGATCGACCACCTGCACCCGGAAGGGAAGATCACCCTGGTGCT
GCACGACTGGGGCGGGATGATCGGCATGGGGTACGCCAACCGGCACCCGGAGCGGATCGGGCGCATCGTGCTCTTGAACA
CGGCCGCCTTCCATCTCCCCAAGGAGAAGCCCTTCCCGCTCGGGCTGAAGATCTGCCGCGATACGGCCCTGGGGACGCTT
CTGGTGCGCGGCTTCAACGCCTTCAGCGTGGGGGCCTCCATCGTCGGCTGCAAGAAAAACCCGATGCCCTGCGAACTGCA
GCAGGCGTACCGCTCCCCCTACGACTCCTGGGCGAACCGCATCGCCACGCTGCGCTTCGTGCAGGACATCCCGCTCGCCC
CCGGCGACCGCAACTACGACCTGGTGAGCGAGATAGCGGCGGGTCTTGAGCGCTTCGCCGATCTCCCCATCGCCATCTTC
TGGGGGGAGCTCGACTTCGTGTTCGACCGGACCTTCCTCGCCGAGTGGAGGCGCCGCTTCCCCAAGGCGAAGGTGAAGAA
CTACCCCGACGCCGGACACTACATCCTGGAAGACATGAAGCAAGAAGTCGTGCCGATGATTGCCGAATTCCTGCGAGAGA
CTAAACCCGGGGAGATCCGTTAA

Upstream 100 bases:

>100_bases
ACGACTCCCGCTCGGGCGACTCCCGCTCAGGGGGACAGGCACCTTGCGGAGCCAGTCCCCTTCAGCGTCCGACGAACACA
CAGACACAGGTGAGTATCTA

Downstream 100 bases:

>100_bases
GGCCATGCTAGAGAGCGAACTGGTCAACATTGCAGCGCACCTGCCGGAGATGGCGAAGCGCCAGCCCGACACGAGGGCCA
TCATCTTCCCCAAGCAGAAC

Product: haloalkane dehalogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTLDIKAHYPFTGRTLDLGGLSYHYLDEGAGEPVVMVHGNPSWSFYYRNLVLALRDNFRCIVPDHIGCGFSDKPGDDRYD
YTLARRIDDLERLIDHLHPEGKITLVLHDWGGMIGMGYANRHPERIGRIVLLNTAAFHLPKEKPFPLGLKICRDTALGTL
LVRGFNAFSVGASIVGCKKNPMPCELQQAYRSPYDSWANRIATLRFVQDIPLAPGDRNYDLVSEIAAGLERFADLPIAIF
WGELDFVFDRTFLAEWRRRFPKAKVKNYPDAGHYILEDMKQEVVPMIAEFLRETKPGEIR

Sequences:

>Translated_300_residues
MTLDIKAHYPFTGRTLDLGGLSYHYLDEGAGEPVVMVHGNPSWSFYYRNLVLALRDNFRCIVPDHIGCGFSDKPGDDRYD
YTLARRIDDLERLIDHLHPEGKITLVLHDWGGMIGMGYANRHPERIGRIVLLNTAAFHLPKEKPFPLGLKICRDTALGTL
LVRGFNAFSVGASIVGCKKNPMPCELQQAYRSPYDSWANRIATLRFVQDIPLAPGDRNYDLVSEIAAGLERFADLPIAIF
WGELDFVFDRTFLAEWRRRFPKAKVKNYPDAGHYILEDMKQEVVPMIAEFLRETKPGEIR
>Mature_299_residues
TLDIKAHYPFTGRTLDLGGLSYHYLDEGAGEPVVMVHGNPSWSFYYRNLVLALRDNFRCIVPDHIGCGFSDKPGDDRYDY
TLARRIDDLERLIDHLHPEGKITLVLHDWGGMIGMGYANRHPERIGRIVLLNTAAFHLPKEKPFPLGLKICRDTALGTLL
VRGFNAFSVGASIVGCKKNPMPCELQQAYRSPYDSWANRIATLRFVQDIPLAPGDRNYDLVSEIAAGLERFADLPIAIFW
GELDFVFDRTFLAEWRRRFPKAKVKNYPDAGHYILEDMKQEVVPMIAEFLRETKPGEIR

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI17562298, Length=310, Percent_Identity=22.5806451612903, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 34198; Mature: 34067

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDIKAHYPFTGRTLDLGGLSYHYLDEGAGEPVVMVHGNPSWSFYYRNLVLALRDNFRC
CEEEEEECCCCCCCEEECCCCEEEEHHCCCCCCEEEEECCCCEEHHHHHHHHEECCCCEE
IVPDHIGCGFSDKPGDDRYDYTLARRIDDLERLIDHLHPEGKITLVLHDWGGMIGMGYAN
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCC
RHPERIGRIVLLNTAAFHLPKEKPFPLGLKICRDTALGTLLVRGFNAFSVGASIVGCKKN
CCHHHHCEEEEEECHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCC
PMPCELQQAYRSPYDSWANRIATLRFVQDIPLAPGDRNYDLVSEIAAGLERFADLPIAIF
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
WGELDFVFDRTFLAEWRRRFPKAKVKNYPDAGHYILEDMKQEVVPMIAEFLRETKPGEIR
ECCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TLDIKAHYPFTGRTLDLGGLSYHYLDEGAGEPVVMVHGNPSWSFYYRNLVLALRDNFRC
EEEEEECCCCCCCEEECCCCEEEEHHCCCCCCEEEEECCCCEEHHHHHHHHEECCCCEE
IVPDHIGCGFSDKPGDDRYDYTLARRIDDLERLIDHLHPEGKITLVLHDWGGMIGMGYAN
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCC
RHPERIGRIVLLNTAAFHLPKEKPFPLGLKICRDTALGTLLVRGFNAFSVGASIVGCKKN
CCHHHHCEEEEEECHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCC
PMPCELQQAYRSPYDSWANRIATLRFVQDIPLAPGDRNYDLVSEIAAGLERFADLPIAIF
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
WGELDFVFDRTFLAEWRRRFPKAKVKNYPDAGHYILEDMKQEVVPMIAEFLRETKPGEIR
ECCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]