Click here to switch to the map view.

The map label for this gene is acpS-2 [H]

Identifier: 197118480

GI number: 197118480

Start: 2423163

End: 2423843

Strand: Reverse

Name: acpS-2 [H]

Synonym: Gbem_2098

Alternate gene names: 197118480

Gene position: 2423843-2423163 (Counterclockwise)

Preceding gene: 197118481

Following gene: 197118475

Centisome position: 52.52

GC content: 62.11

Gene sequence:

>681_bases
TTGATACCGGTTCCGGGCGAGGAAGGAGTCTTCTTCGAGCTGGCTTCCCTGGACCGCTCCGAAGCGGAAAGAAAGCGTCT
GTTCGCCCACCTCTCGCCGGATGAACTGCTGCGGGGTGATCGTCTTTTGGACCCGGTAAAAAGAGAGCGATTCCTAGTGG
GGCGAGGGATACTGCGCGAACTGCTGGGGGGGGTGACCGGGGAAGAAGCGCGGGAAATCGGATTTGCTTCTGGGGAACAC
GGCAAACCGTCGCTGCAGCGTGATGCCGCAAACGGTCCCATAGGTTTCAACGCGTCACATTCCGGTTCATGCCTTCTGGT
CGGCGTCGTCTTCAGCGGCGAGGTGGGGGTGGACCTGGAAGAGCTGCGGCCGGATCTCGACTTCGCGCCCATAGCCCGGC
GCTACTTCTCTCCCCGCGAGCAGCAAGAGCTGTTCAGCCTGCCCTGGAAAGAGCAACTGACCGCTTTCTACCGCTGCTGG
ACCCGCAAGGAAGCCTACCTGAAGGGAATCGGCACCGGCTTTTCGCAACCTTCCACCTGCTTCGACATGTCGCTCTTGCC
CGGAGAAAAGCCGGCGCTCCTGGCGCACCGGATCACGCCGGAGGACGTCGGCAGGTGGCGCCTGCACGATCTACCCGTCC
AAACCGGCTACTGCGCCGCTATCGCCGTTCTGAACCACTGA

Upstream 100 bases:

>100_bases
GGTTCGACCTCTCCGCTGCGCGCGCCGATCTCGGTTACCACCCCCGCATATCCATCGACGAAGGGCTTAGGCTGCTGCAA
GACGCCCTGAGGCAAGGTCG

Downstream 100 bases:

>100_bases
TCACGAACAGCACCCGCCCCCACTTTCGCCGTTACCCTCGCTCGGTCCATCGTTATGACTCCCCCCTCCCGTCTAGGGAG
GGGGAGAGGTCGAAGCGGAC

Product: acyl carrier protein 4'-phosphopantetheinyl transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MIPVPGEEGVFFELASLDRSEAERKRLFAHLSPDELLRGDRLLDPVKRERFLVGRGILRELLGGVTGEEAREIGFASGEH
GKPSLQRDAANGPIGFNASHSGSCLLVGVVFSGEVGVDLEELRPDLDFAPIARRYFSPREQQELFSLPWKEQLTAFYRCW
TRKEAYLKGIGTGFSQPSTCFDMSLLPGEKPALLAHRITPEDVGRWRLHDLPVQTGYCAAIAVLNH

Sequences:

>Translated_226_residues
MIPVPGEEGVFFELASLDRSEAERKRLFAHLSPDELLRGDRLLDPVKRERFLVGRGILRELLGGVTGEEAREIGFASGEH
GKPSLQRDAANGPIGFNASHSGSCLLVGVVFSGEVGVDLEELRPDLDFAPIARRYFSPREQQELFSLPWKEQLTAFYRCW
TRKEAYLKGIGTGFSQPSTCFDMSLLPGEKPALLAHRITPEDVGRWRLHDLPVQTGYCAAIAVLNH
>Mature_226_residues
MIPVPGEEGVFFELASLDRSEAERKRLFAHLSPDELLRGDRLLDPVKRERFLVGRGILRELLGGVTGEEAREIGFASGEH
GKPSLQRDAANGPIGFNASHSGSCLLVGVVFSGEVGVDLEELRPDLDFAPIARRYFSPREQQELFSLPWKEQLTAFYRCW
TRKEAYLKGIGTGFSQPSTCFDMSLLPGEKPALLAHRITPEDVGRWRLHDLPVQTGYCAAIAVLNH

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Escherichia coli, GI1789886, Length=125, Percent_Identity=38.4, Blast_Score=74, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 25130; Mature: 25130

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVPGEEGVFFELASLDRSEAERKRLFAHLSPDELLRGDRLLDPVKRERFLVGRGILRE
CCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHCCCHHHCHHHHHHHHHHHHHHHH
LLGGVTGEEAREIGFASGEHGKPSLQRDAANGPIGFNASHSGSCLLVGVVFSGEVGVDLE
HHCCCCCCHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHH
ELRPDLDFAPIARRYFSPREQQELFSLPWKEQLTAFYRCWTRKEAYLKGIGTGFSQPSTC
HHCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
FDMSLLPGEKPALLAHRITPEDVGRWRLHDLPVQTGYCAAIAVLNH
EEEECCCCCCCCCEEECCCHHHCCCEEEECCCCCCCCEEHEEEECC
>Mature Secondary Structure
MIPVPGEEGVFFELASLDRSEAERKRLFAHLSPDELLRGDRLLDPVKRERFLVGRGILRE
CCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHCCCHHHCHHHHHHHHHHHHHHHH
LLGGVTGEEAREIGFASGEHGKPSLQRDAANGPIGFNASHSGSCLLVGVVFSGEVGVDLE
HHCCCCCCHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHH
ELRPDLDFAPIARRYFSPREQQELFSLPWKEQLTAFYRCWTRKEAYLKGIGTGFSQPSTC
HHCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
FDMSLLPGEKPALLAHRITPEDVGRWRLHDLPVQTGYCAAIAVLNH
EEEECCCCCCCCCEEECCCHHHCCCEEEECCCCCCCCEEHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]