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The map label for this gene is aroB [H]

Identifier: 197118444

GI number: 197118444

Start: 2375473

End: 2376375

Strand: Direct

Name: aroB [H]

Synonym: Gbem_2062

Alternate gene names: 197118444

Gene position: 2375473-2376375 (Clockwise)

Preceding gene: 197118443

Following gene: 197118445

Centisome position: 51.47

GC content: 62.68

Gene sequence:

>903_bases
ATGAACCACACCGTAGCCGCCATCGACCTTGGCACCAATACCGCGAGGCTGCTCATCGCCGGCCGTGACCCCTACCGCCA
GATACTTTTGAAACGGATCATCACCAGGCTCGGGGGGGGCTTTACCCGTGAGCGCGGACTCTCCGAGGAGGCGCAGCTTC
GTTCCATCGCCGCCTTGAAGGAGTTCGCGCTCGACATGTCGCACCACGGCGTGGTCCGGCTGCGGGCGGTTACCACCAGC
GCCGTTAGGGACGCGAAAAACGGTGAAGAGTTCGTGCAAAGGGTGCTTGCCGAGACCGGCATCGCTTTGGAGGTGATCGA
CGGCACGGAGGAGGCGGTGCTGACGCTGAGAGGGGTGGGCTCGATCCTGGATCGCAAGGAATGCGACCTGGCAGTCTTCG
ACGTGGGAGGCGGGAGCACCGAGTACACCCTCGCCTCTGACCTGCAGCCGGTATTCTCCCGCAGCCTCCCTATCGGCGTG
GTCAGGCTCACCGAAGGGAAGGCCGGGGTCGTAGAGATGGAGGACAAGATCAGTCGCGAGCTGACCGCGCTGCAAAAGGA
ACTGGCGGCGCAGGGGCTCGAGGAGCGCTTCAGGAAGGCGACGCTGGTAGGGACCGCAGGGACCGCCACGACACTTGCCG
CCATAGACATGGGGATGGAAGATTACGATTACAAGCGGGTGAACAACCACACCATGCCGCTTGCCGCCGTGGAAAAGATA
TACCGGCAGCTACTGCCGCTGACGCCGCAACAGAGGCTCGAAGTGAAAGGGCTGGAACCAGGGCGCGAGGACCTCATCAT
AGCCGGGGTACTGGTGGTTCTCACCACCATGCGCATCTTCGGCTTCGAGACCTTCAAGGTGAGCGACTCGGGGCTGCTCG
AAGGGCTGATACTAGGGGTTTGA

Upstream 100 bases:

>100_bases
GCATCGTGGCGGGGCTTCTCTACGGCGACATGATCATCGCCTTCTGCAAGATCTCCGAACTATGCTTCTCCATCATCTCC
CAGAAAAAAGGAATCGCCGC

Downstream 100 bases:

>100_bases
GCCCGGGTCAGGCCGGATGCTTCTTTGCCCCCGGTTCACGTTGCGTCTGCCGCTGATGACCCCCTTTCCTGCCGTTGCGC
TGCGCGCGAAAGGGTGCAAA

Product: exopolyphosphatase/guanosine pentaphosphate phosphohydrolase N-terminal domain-containing protein

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNHTVAAIDLGTNTARLLIAGRDPYRQILLKRIITRLGGGFTRERGLSEEAQLRSIAALKEFALDMSHHGVVRLRAVTTS
AVRDAKNGEEFVQRVLAETGIALEVIDGTEEAVLTLRGVGSILDRKECDLAVFDVGGGSTEYTLASDLQPVFSRSLPIGV
VRLTEGKAGVVEMEDKISRELTALQKELAAQGLEERFRKATLVGTAGTATTLAAIDMGMEDYDYKRVNNHTMPLAAVEKI
YRQLLPLTPQQRLEVKGLEPGREDLIIAGVLVVLTTMRIFGFETFKVSDSGLLEGLILGV

Sequences:

>Translated_300_residues
MNHTVAAIDLGTNTARLLIAGRDPYRQILLKRIITRLGGGFTRERGLSEEAQLRSIAALKEFALDMSHHGVVRLRAVTTS
AVRDAKNGEEFVQRVLAETGIALEVIDGTEEAVLTLRGVGSILDRKECDLAVFDVGGGSTEYTLASDLQPVFSRSLPIGV
VRLTEGKAGVVEMEDKISRELTALQKELAAQGLEERFRKATLVGTAGTATTLAAIDMGMEDYDYKRVNNHTMPLAAVEKI
YRQLLPLTPQQRLEVKGLEPGREDLIIAGVLVVLTTMRIFGFETFKVSDSGLLEGLILGV
>Mature_300_residues
MNHTVAAIDLGTNTARLLIAGRDPYRQILLKRIITRLGGGFTRERGLSEEAQLRSIAALKEFALDMSHHGVVRLRAVTTS
AVRDAKNGEEFVQRVLAETGIALEVIDGTEEAVLTLRGVGSILDRKECDLAVFDVGGGSTEYTLASDLQPVFSRSLPIGV
VRLTEGKAGVVEMEDKISRELTALQKELAAQGLEERFRKATLVGTAGTATTLAAIDMGMEDYDYKRVNNHTMPLAAVEKI
YRQLLPLTPQQRLEVKGLEPGREDLIIAGVLVVLTTMRIFGFETFKVSDSGLLEGLILGV

Specific function: Degradation Of Inorganic Polyphosphates. Orthophosphate Is Released Progressively From The Ends Of Polyphosphate Of Circa 500 Residues Long, While Chains Of Circa 15 Residues Compete Poorly With Polyphosphate As Substrate. [C]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=300, Percent_Identity=27.3333333333333, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994966, Length=308, Percent_Identity=26.9480519480519, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 32646; Mature: 32646

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHTVAAIDLGTNTARLLIAGRDPYRQILLKRIITRLGGGFTRERGLSEEAQLRSIAALK
CCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHH
EFALDMSHHGVVRLRAVTTSAVRDAKNGEEFVQRVLAETGIALEVIDGTEEAVLTLRGVG
HHHHCCCCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCHHHHEEHHHHH
SILDRKECDLAVFDVGGGSTEYTLASDLQPVFSRSLPIGVVRLTEGKAGVVEMEDKISRE
HHHCCCCCCEEEEECCCCCCCEEEHHCCHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHH
LTALQKELAAQGLEERFRKATLVGTAGTATTLAAIDMGMEDYDYKRVNNHTMPLAAVEKI
HHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHH
YRQLLPLTPQQRLEVKGLEPGREDLIIAGVLVVLTTMRIFGFETFKVSDSGLLEGLILGV
HHHHCCCCCHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCC
>Mature Secondary Structure
MNHTVAAIDLGTNTARLLIAGRDPYRQILLKRIITRLGGGFTRERGLSEEAQLRSIAALK
CCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHH
EFALDMSHHGVVRLRAVTTSAVRDAKNGEEFVQRVLAETGIALEVIDGTEEAVLTLRGVG
HHHHCCCCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCHHHHEEHHHHH
SILDRKECDLAVFDVGGGSTEYTLASDLQPVFSRSLPIGVVRLTEGKAGVVEMEDKISRE
HHHCCCCCCEEEEECCCCCCCEEEHHCCHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHH
LTALQKELAAQGLEERFRKATLVGTAGTATTLAAIDMGMEDYDYKRVNNHTMPLAAVEKI
HHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHH
YRQLLPLTPQQRLEVKGLEPGREDLIIAGVLVVLTTMRIFGFETFKVSDSGLLEGLILGV
HHHHCCCCCHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]