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The map label for this gene is bphB [H]

Identifier: 197118336

GI number: 197118336

Start: 2256776

End: 2258674

Strand: Direct

Name: bphB [H]

Synonym: Gbem_1953

Alternate gene names: 197118336

Gene position: 2256776-2258674 (Clockwise)

Preceding gene: 197118335

Following gene: 197118337

Centisome position: 48.9

GC content: 62.24

Gene sequence:

>1899_bases
ATGATCAAGCAGAAAAACCGGATCCGCAGCTTCGCGCTGCTTTTGGCCGGTTTCTGGACCATTGCCATCGGGATCTCGTT
TGCCTGGCTCTATCATCACGAAAAGGACAGCGTGGTGGAAGTGGCGCGTGCCGAGGCCCGCGCCTCCTTCAACAAGGACG
CCCTGTTTCGCCGCTGGGGAAACAGGCACGGCGGCGTCTATGCCGCGGTTACCGATACCACCCTCCCGAACCCTTACCTG
GCCCACATACCCGAACGTGACCTAACCACCCCCTCCGGCAGGCGGCTTACCCTCATCAACCCGGCATACATGATGCGGCA
GGTCTTCGAACTGGCGGACGGCCATGGCGACCTGGTTCGCGGCCACCTCACCAGCTTGAAGCCGCTGCGCCCCGAAAACA
CCCCCGACCCTTGGGAGGCGAATGCGCTCCGTCAGTTCGATAACGGGGTCCAGGAGGTGAGCGAGATCCAAAATGTCGGC
GGCCACGTGCAGTTGAGGCTCATGCGGCCCTTCATAACAGAGGAGGGATGCCTTAAATGCCACGCGGCGCAGGGATACAA
GGCGGGGGACGTGCGGGGAGGGGTCAGCGTTTCCGTTCCGCTCGAGAACAAGGAGGGGTATGCCGAAAGCGCCGTCGTAG
TCGGCCTTCTTAGCTACGGGGTGCTCTGGGTCTTCGGGATGGGGTTGATTCTGGTCGGAGCCAGGGTGCTTTCCAGGAAT
TTGAGCATCCTGGAGGAGAGCGAGGAGCGCTACCGCACCGTGGCGAACTACACCGCCGACTGGGAGTACTGGCAGGGGCT
CGACGGTTCCTTCAAATACATCTCCCCCTCCTGCAAGGAGATCTCGGATTACAGTCACGACGAGTTCCATGGCGACCCAG
GGCTCATACAGCGGATCGTCCACCCGGACGACCTCGCAGCCTTCGATGGCCACTTGCATGCGGCGAGGCAAGGGGCGGCC
GAGCCGATCGACTTCCGTATCGTCAGGCGCGACGGCGAAGTTAGGTGGATCTCGCACGTCTGCCAGATGGTGTACACAAG
CGAAGGGGCCGAGAACGGCATCCGCGCCAGCAACCGGGATATCACCGACCGCAAGAAGGTCGAGGCAGCAGTGAAGGAGC
AGGCAGCGCTCCTGGAAAACGAGGTGCGCGAGCGGATGGTGCGCGAGGTGGAACTGGAGGCGAAGAACGCGGAGTTGGAG
CGTTTCACCTACACGGTCTCCCACGACTTGAAGAGCCCGCTCATCACCATCAAAGGGTTCGCCGGTGCGGTCCTTAAGGA
CATCGAGGCCGGGAAGCTCTCGCGGCTCGATTCGGACGTAAAAAGGATCATGGGGGCCGCCGACAAGATGGCCGCGCTTT
TAAGCGATCTCTTGGAGCTATCGAGGATCGGCCGCATCATGAACCCTCCCACCCGGATCGATCTGAACCTGCTGGCGCAG
GAGGTGCTGGGACAGCTTTCCGGCCCGATCGCGCAGGGCGGGGTGGAGGTGGTCCTGCAGCCGGGGCTACCCGCGGTCTG
GGGAGACGCGCCGCGCATTGCCGAGGTGCTGCAAAACCTGGTGGAGAACGCGGTGAAGTACATGGGGGATCAACTGCAGC
CGCTGGTGGAGATCGGCGTACGGGAAGGGCAGGGCGAGCAGGTGTTCTGGGTACGGGACAACGGCATGGGGATCGCGGAG
CAGTATCGGGAAACCGTCTTCGGGCTCTTCAACAAGCTCGACCCGCACTCCGAAGGTACCGGTATCGGACTCGCTCTGGC
GCGCCGCATCATAGAATTCCACAACGGAAGGCTGTGGGTGGAGTCGGAAGGCCCAAGCCTTGGGAGCACCTTCTGCTTTA
CGCTCGGGGCCAAGAACCCCGCTGACAATGACAGTGCCACAAAAGGAGGGACAACATGA

Upstream 100 bases:

>100_bases
CGGAATTGATCATGAAGCCGGTCAAGCCTGCCCTCTTGCTCAAGAAGGTGCGGGAGATGCTGGACCGGCCCCCGCGGATA
TCAGGCAGGGGAGGGAAAGC

Downstream 100 bases:

>100_bases
ACGGCGAACCGCTTTGCATCCTGCTGGTCGAGGACAACCCAGATCACGCCGAGCTGGCTATCCGTAACCTCGACGACGGC
AAGCTTGCCAACAAGATCTT

Product: PAS/PAC domain-containing heme-binding containing sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 632; Mature: 632

Protein sequence:

>632_residues
MIKQKNRIRSFALLLAGFWTIAIGISFAWLYHHEKDSVVEVARAEARASFNKDALFRRWGNRHGGVYAAVTDTTLPNPYL
AHIPERDLTTPSGRRLTLINPAYMMRQVFELADGHGDLVRGHLTSLKPLRPENTPDPWEANALRQFDNGVQEVSEIQNVG
GHVQLRLMRPFITEEGCLKCHAAQGYKAGDVRGGVSVSVPLENKEGYAESAVVVGLLSYGVLWVFGMGLILVGARVLSRN
LSILEESEERYRTVANYTADWEYWQGLDGSFKYISPSCKEISDYSHDEFHGDPGLIQRIVHPDDLAAFDGHLHAARQGAA
EPIDFRIVRRDGEVRWISHVCQMVYTSEGAENGIRASNRDITDRKKVEAAVKEQAALLENEVRERMVREVELEAKNAELE
RFTYTVSHDLKSPLITIKGFAGAVLKDIEAGKLSRLDSDVKRIMGAADKMAALLSDLLELSRIGRIMNPPTRIDLNLLAQ
EVLGQLSGPIAQGGVEVVLQPGLPAVWGDAPRIAEVLQNLVENAVKYMGDQLQPLVEIGVREGQGEQVFWVRDNGMGIAE
QYRETVFGLFNKLDPHSEGTGIGLALARRIIEFHNGRLWVESEGPSLGSTFCFTLGAKNPADNDSATKGGTT

Sequences:

>Translated_632_residues
MIKQKNRIRSFALLLAGFWTIAIGISFAWLYHHEKDSVVEVARAEARASFNKDALFRRWGNRHGGVYAAVTDTTLPNPYL
AHIPERDLTTPSGRRLTLINPAYMMRQVFELADGHGDLVRGHLTSLKPLRPENTPDPWEANALRQFDNGVQEVSEIQNVG
GHVQLRLMRPFITEEGCLKCHAAQGYKAGDVRGGVSVSVPLENKEGYAESAVVVGLLSYGVLWVFGMGLILVGARVLSRN
LSILEESEERYRTVANYTADWEYWQGLDGSFKYISPSCKEISDYSHDEFHGDPGLIQRIVHPDDLAAFDGHLHAARQGAA
EPIDFRIVRRDGEVRWISHVCQMVYTSEGAENGIRASNRDITDRKKVEAAVKEQAALLENEVRERMVREVELEAKNAELE
RFTYTVSHDLKSPLITIKGFAGAVLKDIEAGKLSRLDSDVKRIMGAADKMAALLSDLLELSRIGRIMNPPTRIDLNLLAQ
EVLGQLSGPIAQGGVEVVLQPGLPAVWGDAPRIAEVLQNLVENAVKYMGDQLQPLVEIGVREGQGEQVFWVRDNGMGIAE
QYRETVFGLFNKLDPHSEGTGIGLALARRIIEFHNGRLWVESEGPSLGSTFCFTLGAKNPADNDSATKGGTT
>Mature_632_residues
MIKQKNRIRSFALLLAGFWTIAIGISFAWLYHHEKDSVVEVARAEARASFNKDALFRRWGNRHGGVYAAVTDTTLPNPYL
AHIPERDLTTPSGRRLTLINPAYMMRQVFELADGHGDLVRGHLTSLKPLRPENTPDPWEANALRQFDNGVQEVSEIQNVG
GHVQLRLMRPFITEEGCLKCHAAQGYKAGDVRGGVSVSVPLENKEGYAESAVVVGLLSYGVLWVFGMGLILVGARVLSRN
LSILEESEERYRTVANYTADWEYWQGLDGSFKYISPSCKEISDYSHDEFHGDPGLIQRIVHPDDLAAFDGHLHAARQGAA
EPIDFRIVRRDGEVRWISHVCQMVYTSEGAENGIRASNRDITDRKKVEAAVKEQAALLENEVRERMVREVELEAKNAELE
RFTYTVSHDLKSPLITIKGFAGAVLKDIEAGKLSRLDSDVKRIMGAADKMAALLSDLLELSRIGRIMNPPTRIDLNLLAQ
EVLGQLSGPIAQGGVEVVLQPGLPAVWGDAPRIAEVLQNLVENAVKYMGDQLQPLVEIGVREGQGEQVFWVRDNGMGIAE
QYRETVFGLFNKLDPHSEGTGIGLALARRIIEFHNGRLWVESEGPSLGSTFCFTLGAKNPADNDSATKGGTT

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG4251

COG function: function code T; Bacteriophytochrome (light-regulated signal transduction histidine kinase)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=291, Percent_Identity=29.553264604811, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI145693157, Length=281, Percent_Identity=26.3345195729537, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=27.9166666666667, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786912, Length=254, Percent_Identity=31.1023622047244, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790346, Length=225, Percent_Identity=28.4444444444444, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=279, Percent_Identity=27.9569892473118, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=360, Percent_Identity=23.6111111111111, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=216, Percent_Identity=28.2407407407407, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790551, Length=214, Percent_Identity=28.5046728971963, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=195, Percent_Identity=29.7435897435897, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69968; Mature: 69968

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQKNRIRSFALLLAGFWTIAIGISFAWLYHHEKDSVVEVARAEARASFNKDALFRRWG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHC
NRHGGVYAAVTDTTLPNPYLAHIPERDLTTPSGRRLTLINPAYMMRQVFELADGHGDLVR
CCCCCEEEEEECCCCCCCHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCHHHH
GHLTSLKPLRPENTPDPWEANALRQFDNGVQEVSEIQNVGGHVQLRLMRPFITEEGCLKC
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHCCCCHHEE
HAAQGYKAGDVRGGVSVSVPLENKEGYAESAVVVGLLSYGVLWVFGMGLILVGARVLSRN
ECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSILEESEERYRTVANYTADWEYWQGLDGSFKYISPSCKEISDYSHDEFHGDPGLIQRIV
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHC
HPDDLAAFDGHLHAARQGAAEPIDFRIVRRDGEVRWISHVCQMVYTSEGAENGIRASNRD
CCCHHHHHCCHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
ITDRKKVEAAVKEQAALLENEVRERMVREVELEAKNAELERFTYTVSHDLKSPLITIKGF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEHHHHCCCCEEEEECH
AGAVLKDIEAGKLSRLDSDVKRIMGAADKMAALLSDLLELSRIGRIMNPPTRIDLNLLAQ
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EVLGQLSGPIAQGGVEVVLQPGLPAVWGDAPRIAEVLQNLVENAVKYMGDQLQPLVEIGV
HHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCC
REGQGEQVFWVRDNGMGIAEQYRETVFGLFNKLDPHSEGTGIGLALARRIIEFHNGRLWV
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEE
ESEGPSLGSTFCFTLGAKNPADNDSATKGGTT
ECCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIKQKNRIRSFALLLAGFWTIAIGISFAWLYHHEKDSVVEVARAEARASFNKDALFRRWG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHC
NRHGGVYAAVTDTTLPNPYLAHIPERDLTTPSGRRLTLINPAYMMRQVFELADGHGDLVR
CCCCCEEEEEECCCCCCCHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCHHHH
GHLTSLKPLRPENTPDPWEANALRQFDNGVQEVSEIQNVGGHVQLRLMRPFITEEGCLKC
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHCCCCHHEE
HAAQGYKAGDVRGGVSVSVPLENKEGYAESAVVVGLLSYGVLWVFGMGLILVGARVLSRN
ECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LSILEESEERYRTVANYTADWEYWQGLDGSFKYISPSCKEISDYSHDEFHGDPGLIQRIV
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHC
HPDDLAAFDGHLHAARQGAAEPIDFRIVRRDGEVRWISHVCQMVYTSEGAENGIRASNRD
CCCHHHHHCCHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
ITDRKKVEAAVKEQAALLENEVRERMVREVELEAKNAELERFTYTVSHDLKSPLITIKGF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEHHHHCCCCEEEEECH
AGAVLKDIEAGKLSRLDSDVKRIMGAADKMAALLSDLLELSRIGRIMNPPTRIDLNLLAQ
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EVLGQLSGPIAQGGVEVVLQPGLPAVWGDAPRIAEVLQNLVENAVKYMGDQLQPLVEIGV
HHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCC
REGQGEQVFWVRDNGMGIAEQYRETVFGLFNKLDPHSEGTGIGLALARRIIEFHNGRLWV
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEE
ESEGPSLGSTFCFTLGAKNPADNDSATKGGTT
ECCCCCCCCEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]