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The map label for this gene is atoS [C]

Identifier: 197118335

GI number: 197118335

Start: 2254701

End: 2256779

Strand: Direct

Name: atoS [C]

Synonym: Gbem_1952

Alternate gene names: 197118335

Gene position: 2254701-2256779 (Clockwise)

Preceding gene: 197118333

Following gene: 197118336

Centisome position: 48.85

GC content: 60.65

Gene sequence:

>2079_bases
ATGGACTCTTCACCCCAGTTCAAACGAATTCTTATCGTGGAAGATGACGAGTCTCACGCGGAACTGATTAGGAGAGGTTT
CAGCGAGGCCTCGGACCACTATCGTCTGACCGTCGCCACCAGTATGCAGGAAGCGCTCGCCAGGGTGCAGAGCAATAATT
TCGACATAGTGCTCACCGATTACCTCCTTCCCGATGGCAAAGGCGTGGACCTGGTGCTGAAAAGCGGGCAGACCACGCCG
GTAGTGATCATGACCTCGCACGGCAACGAACAACTCGCAGTCGACGCCATGAAGGCCGGCGCGCTCGATTACGTGGTCAA
AATGCCTGAGGTATTCGAGGCAATGCCGCGCATCATAGAACGCGCCTTGCGCGAATGGGACTTGATGCTCGAACACAAGC
ACGCCGTGGACGCGCTCCTGTTGCAGACCCGTCAACTTGAACATGAGGTGGCCGAGCGGCAGATCGCCCAGGAGGCGCTG
CAGGCGCAAGCGGTGCTTTTGCAAAACGAGATCGCGGAGCGCCGGCAGGCCCAGGAGACTCAGCGGCTTTCGGAGGAAAA
ATTCTCGAAGGCCTTCGACAACGCTCCCATGATCATGACCATCACGATGCGGGAAAACGGCACCCTCCTCGACGTCAACA
ACAGGTTCCTGGAAGTTTCCGGCTGGTGCCGGGAAGATGTCATCGGCAAGACCACCAGAGAGGTCGGCTGGATCAACAAC
GACGACCGGGCAATTCTGTTCGAGACCCTCAATCGGGAAGGGCATGTCTCGGGGTTGGCATTGAGCCTCCACCCAAGGGG
CGGGCGGACCATCAAGGCCGAACTCTACATAGAGACCATCACCGTGGACGGCAGCGAACGCCTTTTGGGGATCGCCATCG
ACGTCACGGAACGGCACAAGCTCGAGGAACAGTTGCGCCACTCCCAGAAGCTGGAAGCGGTCGGCCTTTTGGCCGGCGGA
GTGGCTCACGACTTCAACAATATCCTCACCGTGATCGGCGGGTACTGCGAGATGCTCAAACTCGATCTCGCGCCCGGCCA
TCCCCTGCGCGACAAGGTGCTGCAGATATCCGCCGCCTCCGAGCGCGCCTCCAACCTGACCCGCAGCCTGCTTGCTTTCA
GCCGCAAGGGGGAGGTGAAGGCGGTTCCGACCGACCTGAACCTGCTGTTGCGAGGGGTGGAGAAGTTCCTGCAGCGCATT
ATCGGCGAGGACATCACCCTTTCCACCAAGGTCCCCGAGAGAGCCATCTGGGCGGTGGTCGATTCGGGGCAGATCGACCA
GGTGCTGATGAATCTCGCGGCCAACGCGAGGGACGCCATGCCCAAGGGGGGGAGCCTGTTCGTGGAGTTGGAGCGCCAGG
AGATCGACGCCGGTTTCGTGCAAGCCCACGGCTTCGGGACTCCCGGCAGCTATGCCCTGCTTACCGTTTCCGATACCGGC
CAGGGGATGGACGAGGAGACTAGGAACAGGATCTTCGATCCGTTTTTCACCACCAAGGTGTCGGGAAAGGGGACAGGGCT
CGGCCTCGCTATCGTCTACGGCATCGTTATCCAGCACAAGGGGTTCGTCAACGTCTACAGCGAGCCCGGTGTGGGCAGCA
CCTTCCGCATCTATCTCCCGGTGGTGGAGCCGCAGCAGCTCGCCGGCACCGAGGCCGTCACCGTCGAGGCTGAGGTGCGC
GGCTGCGAGACCATCTTGGTTGCCGAGGACGATCTGTACGTCCTGGACCTGGTGACGAACGTCCTCGTGCAGTACGGCTA
CAGCATCATCCATGCTGCCAACGGGGAGGAAGCCGTGCAGAAGTTCCAGGAGAACGACCAGATAGCGCTGGTGCTGATGG
ACATCATCATGCCGGTCATGAACGGCAAGGAGGCCGCCGAAAAGATCCGGCGGCTGCGGCCCGAGGCCAGGATTCTTTTC
ACCAGCGGCTACACGGCGGAGATAATCAAGAGCAGATGCGAGTTGGAGGAGAGTGCGGAATTGATCATGAAGCCGGTCAA
GCCTGCCCTCTTGCTCAAGAAGGTGCGGGAGATGCTGGACCGGCCCCCGCGGATATCAGGCAGGGGAGGGAAAGCATGA

Upstream 100 bases:

>100_bases
CTATGGACTTGCAACCTGTATCAATTGAGGAGCATTCCCTTTGTCTGCTCTGACAGGTGCGGTAAAGTGCCCTGGTTGTA
CCAGAGCAGGAGCTGACGCC

Downstream 100 bases:

>100_bases
TCAAGCAGAAAAACCGGATCCGCAGCTTCGCGCTGCTTTTGGCCGGTTTCTGGACCATTGCCATCGGGATCTCGTTTGCC
TGGCTCTATCATCACGAAAA

Product: response receiver histidine kinase response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MDSSPQFKRILIVEDDESHAELIRRGFSEASDHYRLTVATSMQEALARVQSNNFDIVLTDYLLPDGKGVDLVLKSGQTTP
VVIMTSHGNEQLAVDAMKAGALDYVVKMPEVFEAMPRIIERALREWDLMLEHKHAVDALLLQTRQLEHEVAERQIAQEAL
QAQAVLLQNEIAERRQAQETQRLSEEKFSKAFDNAPMIMTITMRENGTLLDVNNRFLEVSGWCREDVIGKTTREVGWINN
DDRAILFETLNREGHVSGLALSLHPRGGRTIKAELYIETITVDGSERLLGIAIDVTERHKLEEQLRHSQKLEAVGLLAGG
VAHDFNNILTVIGGYCEMLKLDLAPGHPLRDKVLQISAASERASNLTRSLLAFSRKGEVKAVPTDLNLLLRGVEKFLQRI
IGEDITLSTKVPERAIWAVVDSGQIDQVLMNLAANARDAMPKGGSLFVELERQEIDAGFVQAHGFGTPGSYALLTVSDTG
QGMDEETRNRIFDPFFTTKVSGKGTGLGLAIVYGIVIQHKGFVNVYSEPGVGSTFRIYLPVVEPQQLAGTEAVTVEAEVR
GCETILVAEDDLYVLDLVTNVLVQYGYSIIHAANGEEAVQKFQENDQIALVLMDIIMPVMNGKEAAEKIRRLRPEARILF
TSGYTAEIIKSRCELEESAELIMKPVKPALLLKKVREMLDRPPRISGRGGKA

Sequences:

>Translated_692_residues
MDSSPQFKRILIVEDDESHAELIRRGFSEASDHYRLTVATSMQEALARVQSNNFDIVLTDYLLPDGKGVDLVLKSGQTTP
VVIMTSHGNEQLAVDAMKAGALDYVVKMPEVFEAMPRIIERALREWDLMLEHKHAVDALLLQTRQLEHEVAERQIAQEAL
QAQAVLLQNEIAERRQAQETQRLSEEKFSKAFDNAPMIMTITMRENGTLLDVNNRFLEVSGWCREDVIGKTTREVGWINN
DDRAILFETLNREGHVSGLALSLHPRGGRTIKAELYIETITVDGSERLLGIAIDVTERHKLEEQLRHSQKLEAVGLLAGG
VAHDFNNILTVIGGYCEMLKLDLAPGHPLRDKVLQISAASERASNLTRSLLAFSRKGEVKAVPTDLNLLLRGVEKFLQRI
IGEDITLSTKVPERAIWAVVDSGQIDQVLMNLAANARDAMPKGGSLFVELERQEIDAGFVQAHGFGTPGSYALLTVSDTG
QGMDEETRNRIFDPFFTTKVSGKGTGLGLAIVYGIVIQHKGFVNVYSEPGVGSTFRIYLPVVEPQQLAGTEAVTVEAEVR
GCETILVAEDDLYVLDLVTNVLVQYGYSIIHAANGEEAVQKFQENDQIALVLMDIIMPVMNGKEAAEKIRRLRPEARILF
TSGYTAEIIKSRCELEESAELIMKPVKPALLLKKVREMLDRPPRISGRGGKA
>Mature_692_residues
MDSSPQFKRILIVEDDESHAELIRRGFSEASDHYRLTVATSMQEALARVQSNNFDIVLTDYLLPDGKGVDLVLKSGQTTP
VVIMTSHGNEQLAVDAMKAGALDYVVKMPEVFEAMPRIIERALREWDLMLEHKHAVDALLLQTRQLEHEVAERQIAQEAL
QAQAVLLQNEIAERRQAQETQRLSEEKFSKAFDNAPMIMTITMRENGTLLDVNNRFLEVSGWCREDVIGKTTREVGWINN
DDRAILFETLNREGHVSGLALSLHPRGGRTIKAELYIETITVDGSERLLGIAIDVTERHKLEEQLRHSQKLEAVGLLAGG
VAHDFNNILTVIGGYCEMLKLDLAPGHPLRDKVLQISAASERASNLTRSLLAFSRKGEVKAVPTDLNLLLRGVEKFLQRI
IGEDITLSTKVPERAIWAVVDSGQIDQVLMNLAANARDAMPKGGSLFVELERQEIDAGFVQAHGFGTPGSYALLTVSDTG
QGMDEETRNRIFDPFFTTKVSGKGTGLGLAIVYGIVIQHKGFVNVYSEPGVGSTFRIYLPVVEPQQLAGTEAVTVEAEVR
GCETILVAEDDLYVLDLVTNVLVQYGYSIIHAANGEEAVQKFQENDQIALVLMDIIMPVMNGKEAAEKIRRLRPEARILF
TSGYTAEIIKSRCELEESAELIMKPVKPALLLKKVREMLDRPPRISGRGGKA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=380, Percent_Identity=26.5789473684211, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=31.2, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786600, Length=268, Percent_Identity=27.6119402985075, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87081816, Length=365, Percent_Identity=26.3013698630137, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=233, Percent_Identity=28.3261802575107, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=567, Percent_Identity=23.2804232804233, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790300, Length=264, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790437, Length=135, Percent_Identity=34.0740740740741, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI145693157, Length=283, Percent_Identity=25.0883392226148, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=29.1497975708502, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76764; Mature: 76764

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSPQFKRILIVEDDESHAELIRRGFSEASDHYRLTVATSMQEALARVQSNNFDIVLTD
CCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEE
YLLPDGKGVDLVLKSGQTTPVVIMTSHGNEQLAVDAMKAGALDYVVKMPEVFEAMPRIIE
EECCCCCCCEEEEECCCCCEEEEEECCCCCEEEHHHHHCCCHHHHHCCHHHHHHHHHHHH
RALREWDLMLEHKHAVDALLLQTRQLEHEVAERQIAQEALQAQAVLLQNEIAERRQAQET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLSEEKFSKAFDNAPMIMTITMRENGTLLDVNNRFLEVSGWCREDVIGKTTREVGWINN
HHHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCCEEEECCCCHHHHCCCCHHHCCCCCC
DDRAILFETLNREGHVSGLALSLHPRGGRTIKAELYIETITVDGSERLLGIAIDVTERHK
CCCEEEEEECCCCCCCCEEEEEEECCCCCEEEEEEEEEEEEECCCCCEEEEEEECHHHHH
LEEQLRHSQKLEAVGLLAGGVAHDFNNILTVIGGYCEMLKLDLAPGHPLRDKVLQISAAS
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHEEEEHHH
ERASNLTRSLLAFSRKGEVKAVPTDLNLLLRGVEKFLQRIIGEDITLSTKVPERAIWAVV
HHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEE
DSGQIDQVLMNLAANARDAMPKGGSLFVELERQEIDAGFVQAHGFGTPGSYALLTVSDTG
CCCCHHHHHHHHHCCHHHCCCCCCCEEEEEEHHHCCCCEEEECCCCCCCCEEEEEEECCC
QGMDEETRNRIFDPFFTTKVSGKGTGLGLAIVYGIVIQHKGFVNVYSEPGVGSTFRIYLP
CCCCHHHHHCCCCCHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEE
VVEPQQLAGTEAVTVEAEVRGCETILVAEDDLYVLDLVTNVLVQYGYSIIHAANGEEAVQ
ECCCHHHCCCEEEEEEEECCCCEEEEEECCCEEHHHHHHHHHHHCCCCEEEECCCHHHHH
KFQENDQIALVLMDIIMPVMNGKEAAEKIRRLRPEARILFTSGYTAEIIKSRCELEESAE
HHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCHHHHHH
LIMKPVKPALLLKKVREMLDRPPRISGRGGKA
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDSSPQFKRILIVEDDESHAELIRRGFSEASDHYRLTVATSMQEALARVQSNNFDIVLTD
CCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEE
YLLPDGKGVDLVLKSGQTTPVVIMTSHGNEQLAVDAMKAGALDYVVKMPEVFEAMPRIIE
EECCCCCCCEEEEECCCCCEEEEEECCCCCEEEHHHHHCCCHHHHHCCHHHHHHHHHHHH
RALREWDLMLEHKHAVDALLLQTRQLEHEVAERQIAQEALQAQAVLLQNEIAERRQAQET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLSEEKFSKAFDNAPMIMTITMRENGTLLDVNNRFLEVSGWCREDVIGKTTREVGWINN
HHHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCCEEEECCCCHHHHCCCCHHHCCCCCC
DDRAILFETLNREGHVSGLALSLHPRGGRTIKAELYIETITVDGSERLLGIAIDVTERHK
CCCEEEEEECCCCCCCCEEEEEEECCCCCEEEEEEEEEEEEECCCCCEEEEEEECHHHHH
LEEQLRHSQKLEAVGLLAGGVAHDFNNILTVIGGYCEMLKLDLAPGHPLRDKVLQISAAS
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHEEEEHHH
ERASNLTRSLLAFSRKGEVKAVPTDLNLLLRGVEKFLQRIIGEDITLSTKVPERAIWAVV
HHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEE
DSGQIDQVLMNLAANARDAMPKGGSLFVELERQEIDAGFVQAHGFGTPGSYALLTVSDTG
CCCCHHHHHHHHHCCHHHCCCCCCCEEEEEEHHHCCCCEEEECCCCCCCCEEEEEEECCC
QGMDEETRNRIFDPFFTTKVSGKGTGLGLAIVYGIVIQHKGFVNVYSEPGVGSTFRIYLP
CCCCHHHHHCCCCCHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEE
VVEPQQLAGTEAVTVEAEVRGCETILVAEDDLYVLDLVTNVLVQYGYSIIHAANGEEAVQ
ECCCHHHCCCEEEEEEEECCCCEEEEEECCCEEHHHHHHHHHHHCCCCEEEECCCHHHHH
KFQENDQIALVLMDIIMPVMNGKEAAEKIRRLRPEARILFTSGYTAEIIKSRCELEESAE
HHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCHHHHHH
LIMKPVKPALLLKKVREMLDRPPRISGRGGKA
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA