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The map label for this gene is yhdH [H]

Identifier: 197118332

GI number: 197118332

Start: 2252033

End: 2253400

Strand: Direct

Name: yhdH [H]

Synonym: Gbem_1949

Alternate gene names: 197118332

Gene position: 2252033-2253400 (Clockwise)

Preceding gene: 197118331

Following gene: 197118333

Centisome position: 48.8

GC content: 60.96

Gene sequence:

>1368_bases
ATGGAAACAGCCAAGGCAGTAAAGGCACGCGACAGTTTCACCACGGGTTTGGGCGTCATCGCCGCTACTCTCGGCTCCGC
GGTGGGGCTGGGCAATATCTGGAAATTCCCGGCGCTGACCGGGCTTAACGGCGGGGCGGCTTTCATCATCGTCTACCTCC
TCTCGACGCTTATGGCCGGACTCCCGGTGATGATCGCGGAACTGATGCTCGGACGCCGCTCGAAGTCCGACGCACTGACC
ACGTTCCGGGTGCTGCACCCCAAACGCGAAACCTGGTCGCTGATCGGCGCGGCAGGGGTTCTTTCTGCCTTTCTCATCCT
TGCCTTTTACACGGAGGTTGCGGGGTGGGTCTTCGCCTATATCTTCAAGGCGGCGTCGGGGAGCATCCTCTCGGCCGATC
CCAAGGTCACTTCGGCCGCCTTCGAAAAACTGATCGCTGACCCGGTGCAGTCGGTCTTCTGGCAGTGCGCGGTCATCGTC
TTCGTCGGCGCCATCATCGTCATGGGGGTTGCCAAGGGAATCGAGAAGACCACCAAACGGCTGATGCCGGTCCTGTTCCT
GATCCTGGTCATGATCGGCGTGCGCAGCCTGATGCTCCCGGGCGCGGCCCAAGGGCTCGATTTCCTTTTCCGCCCCGACT
TTTCCAAGGTCACCGGCGCCGTGGTGCTCACCGCGATGGGGCTTGCCTTCTTCAAGCTCTCGGTCGGGATGGGGACCATG
ATCACCTACGGGAGCTACTTCAGGGACGACCAGAACGTTCCCATGACCGCTCTGCGCGTGATGCTTGCCGACCTCACCGT
TTCCATCCTGGCTGGGATCGCCATCTTCCCTGCTGTGTTCACCTTCGGGTTCAAGCCTGAGGCCGGGCCGTCGCTTCTCT
TCATCACCATCCCGGCGGTGTTCTCCCAGATGCCTTTCGGGAACGTCTTCGTGGTCCTCTTCTTCGTCCTCGGGGCCATC
GCCGCGACCGGCGCCATGCTCTCCATCATGGAGGTGCCGGTCGCCTATCTGCACCAGCGCTTCGGCGTGAGCCGCTTCAA
GGCCACGGCTGCCACCGGCATCCTGCTGGCTTTGATCGGGTCTACTGCCGCACTCTCCAACAGCGTCCTCGCAAACTTCA
AGCTGTTCGGCATGACCATGTTCGACCTGTACGACTTCCTTACCTCCAACCTGCTGATGCCGGTAGGGGGGCTCTTCATC
TGCATCTTCGTTGGGTGGGTGTGGGGGGAGCAGAAGGTGAGGGGGGCATTGTCCAATGACGGCAGGCTGCAAAACAGCGC
CGTAATAAGCATCTTCTTCTTCCTGGTGAAGTATGTGGCGCCCATCACCATCGGCGTCATCCTGCTGCGCGGATTGAAGA
TCATATAG

Upstream 100 bases:

>100_bases
AAGTACCGGCGGCGTAGGCAGCACCTACCCCACCCCCTAACCCCCTCCCGCCAGTGGAGGGGGGACTTTTAATGCCGCAA
ACAAAGGAAAAATGCAAAGC

Downstream 100 bases:

>100_bases
CTACTTCGCGCCCCCTCCCGCAGGGGGCGCTAACTTACCGGAACCCGATATGACCAAACCTGCCGACACTTCCGAACTGG
CTGCGACCGAGGCGCGGCGC

Product: sodium-dependent transporter, SNF family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
METAKAVKARDSFTTGLGVIAATLGSAVGLGNIWKFPALTGLNGGAAFIIVYLLSTLMAGLPVMIAELMLGRRSKSDALT
TFRVLHPKRETWSLIGAAGVLSAFLILAFYTEVAGWVFAYIFKAASGSILSADPKVTSAAFEKLIADPVQSVFWQCAVIV
FVGAIIVMGVAKGIEKTTKRLMPVLFLILVMIGVRSLMLPGAAQGLDFLFRPDFSKVTGAVVLTAMGLAFFKLSVGMGTM
ITYGSYFRDDQNVPMTALRVMLADLTVSILAGIAIFPAVFTFGFKPEAGPSLLFITIPAVFSQMPFGNVFVVLFFVLGAI
AATGAMLSIMEVPVAYLHQRFGVSRFKATAATGILLALIGSTAALSNSVLANFKLFGMTMFDLYDFLTSNLLMPVGGLFI
CIFVGWVWGEQKVRGALSNDGRLQNSAVISIFFFLVKYVAPITIGVILLRGLKII

Sequences:

>Translated_455_residues
METAKAVKARDSFTTGLGVIAATLGSAVGLGNIWKFPALTGLNGGAAFIIVYLLSTLMAGLPVMIAELMLGRRSKSDALT
TFRVLHPKRETWSLIGAAGVLSAFLILAFYTEVAGWVFAYIFKAASGSILSADPKVTSAAFEKLIADPVQSVFWQCAVIV
FVGAIIVMGVAKGIEKTTKRLMPVLFLILVMIGVRSLMLPGAAQGLDFLFRPDFSKVTGAVVLTAMGLAFFKLSVGMGTM
ITYGSYFRDDQNVPMTALRVMLADLTVSILAGIAIFPAVFTFGFKPEAGPSLLFITIPAVFSQMPFGNVFVVLFFVLGAI
AATGAMLSIMEVPVAYLHQRFGVSRFKATAATGILLALIGSTAALSNSVLANFKLFGMTMFDLYDFLTSNLLMPVGGLFI
CIFVGWVWGEQKVRGALSNDGRLQNSAVISIFFFLVKYVAPITIGVILLRGLKII
>Mature_455_residues
METAKAVKARDSFTTGLGVIAATLGSAVGLGNIWKFPALTGLNGGAAFIIVYLLSTLMAGLPVMIAELMLGRRSKSDALT
TFRVLHPKRETWSLIGAAGVLSAFLILAFYTEVAGWVFAYIFKAASGSILSADPKVTSAAFEKLIADPVQSVFWQCAVIV
FVGAIIVMGVAKGIEKTTKRLMPVLFLILVMIGVRSLMLPGAAQGLDFLFRPDFSKVTGAVVLTAMGLAFFKLSVGMGTM
ITYGSYFRDDQNVPMTALRVMLADLTVSILAGIAIFPAVFTFGFKPEAGPSLLFITIPAVFSQMPFGNVFVVLFFVLGAI
AATGAMLSIMEVPVAYLHQRFGVSRFKATAATGILLALIGSTAALSNSVLANFKLFGMTMFDLYDFLTSNLLMPVGGLFI
CIFVGWVWGEQKVRGALSNDGRLQNSAVISIFFFLVKYVAPITIGVILLRGLKII

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=463, Percent_Identity=24.8380129589633, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI21361581, Length=459, Percent_Identity=23.7472766884532, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4507043, Length=359, Percent_Identity=26.1838440111421, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI171184408, Length=468, Percent_Identity=22.6495726495727, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI171184406, Length=468, Percent_Identity=22.6495726495727, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI171184404, Length=468, Percent_Identity=22.6495726495727, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI194018524, Length=307, Percent_Identity=28.6644951140065, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI7657587, Length=469, Percent_Identity=23.6673773987207, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI58219014, Length=319, Percent_Identity=28.2131661442006, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI92859670, Length=419, Percent_Identity=24.1050119331742, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI11181770, Length=307, Percent_Identity=27.3615635179153, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI5032097, Length=474, Percent_Identity=24.6835443037975, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI134304856, Length=347, Percent_Identity=25.6484149855908, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI51468073, Length=314, Percent_Identity=23.8853503184713, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI197276623, Length=479, Percent_Identity=23.1732776617954, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI54607094, Length=479, Percent_Identity=23.1732776617954, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI33354281, Length=315, Percent_Identity=25.0793650793651, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI289191351, Length=381, Percent_Identity=23.8845144356955, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4557046, Length=381, Percent_Identity=23.8845144356955, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI289191377, Length=381, Percent_Identity=23.8845144356955, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI218563756, Length=463, Percent_Identity=24.622030237581, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4507041, Length=500, Percent_Identity=24.6, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI12408638, Length=284, Percent_Identity=26.7605633802817, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI300360519, Length=388, Percent_Identity=21.9072164948454, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI21361693, Length=215, Percent_Identity=24.1860465116279, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI197276625, Length=123, Percent_Identity=30.0813008130081, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17554804, Length=483, Percent_Identity=26.7080745341615, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17555248, Length=383, Percent_Identity=26.8929503916449, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI133952791, Length=416, Percent_Identity=26.2019230769231, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI25146584, Length=403, Percent_Identity=24.317617866005, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71998244, Length=437, Percent_Identity=24.7139588100687, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17569475, Length=411, Percent_Identity=25.3041362530414, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17535731, Length=125, Percent_Identity=32.8, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542050, Length=121, Percent_Identity=33.0578512396694, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71995588, Length=83, Percent_Identity=36.144578313253, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550877, Length=395, Percent_Identity=24.5569620253165, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45551183, Length=395, Percent_Identity=24.5569620253165, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17136952, Length=385, Percent_Identity=22.5974025974026, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24762620, Length=355, Percent_Identity=26.7605633802817, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281364136, Length=524, Percent_Identity=22.9007633587786, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281364394, Length=385, Percent_Identity=22.5974025974026, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574704, Length=385, Percent_Identity=22.5974025974026, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17136950, Length=385, Percent_Identity=22.5974025974026, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574702, Length=385, Percent_Identity=22.5974025974026, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19921936, Length=468, Percent_Identity=24.7863247863248, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221329674, Length=508, Percent_Identity=24.0157480314961, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24639514, Length=508, Percent_Identity=24.0157480314961, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24652942, Length=459, Percent_Identity=24.6187363834423, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45551088, Length=459, Percent_Identity=24.6187363834423, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24639516, Length=525, Percent_Identity=22.8571428571429, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24661428, Length=506, Percent_Identity=23.7154150197628, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281365034, Length=475, Percent_Identity=22.3157894736842, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24655079, Length=306, Percent_Identity=25.4901960784314, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19921352, Length=481, Percent_Identity=23.0769230769231, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24584353, Length=481, Percent_Identity=23.0769230769231, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363702, Length=380, Percent_Identity=23.6842105263158, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24582567, Length=450, Percent_Identity=23.3333333333333, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639853, Length=485, Percent_Identity=21.4432989690722, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654186, Length=274, Percent_Identity=26.6423357664234, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48611; Mature: 48611

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METAKAVKARDSFTTGLGVIAATLGSAVGLGNIWKFPALTGLNGGAAFIIVYLLSTLMAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
LPVMIAELMLGRRSKSDALTTFRVLHPKRETWSLIGAAGVLSAFLILAFYTEVAGWVFAY
HHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFKAASGSILSADPKVTSAAFEKLIADPVQSVFWQCAVIVFVGAIIVMGVAKGIEKTTKR
HHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMPVLFLILVMIGVRSLMLPGAAQGLDFLFRPDFSKVTGAVVLTAMGLAFFKLSVGMGTM
HHHHHHHHHHHHHHHHHHCCCCHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
ITYGSYFRDDQNVPMTALRVMLADLTVSILAGIAIFPAVFTFGFKPEAGPSLLFITIPAV
HHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHH
FSQMPFGNVFVVLFFVLGAIAATGAMLSIMEVPVAYLHQRFGVSRFKATAATGILLALIG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
STAALSNSVLANFKLFGMTMFDLYDFLTSNLLMPVGGLFICIFVGWVWGEQKVRGALSND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCC
GRLQNSAVISIFFFLVKYVAPITIGVILLRGLKII
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]