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The map label for this gene is recG [H]

Identifier: 197118286

GI number: 197118286

Start: 2204354

End: 2206672

Strand: Direct

Name: recG [H]

Synonym: Gbem_1903

Alternate gene names: 197118286

Gene position: 2204354-2206672 (Clockwise)

Preceding gene: 197118285

Following gene: 197118291

Centisome position: 47.76

GC content: 64.08

Gene sequence:

>2319_bases
ATGCCGACGATAACCCTCGCGCCAGACGGGTCCATCCCGCTTCCGGAACAGCTCAGGAATGATCTGAAGCTTCGCCCGGG
GGACCTGGTGAGCGTAGAGGTCGTCGATGGGACCCTACGTATCTCCAAGCAAAAATCAGCCAAAGAAACACGCTCTACCC
CCCCCGCAGCAAAGCCCGCAGCCGCCGTCGCGCAGGTAACCGTCCCCGAAGAACTGAAGACCCCGATGCAGAGCATCAAG
GGGGTAGGGCCGAAGCTTGCCGCCACCCTTTCCAAAAAGGGGCTGGACACGGTCGAGGATGCGCTTTATCTTCTCCCCAA
CCGCTACGAGGATCGCCGCGAACTAAAGAAGATAGCGCAACTGCGCCCCGGCAACAGCGAGGCCTTCTTCGCCACCGTCG
TTTCGGCCGCGGCGCAAACCACCAAGGGGGGACGGCGCTACTTCGAGGCCATCGTCAAGGACGAAACGGGTAGCCTGCCG
CTCAAGTGGTTCCATTTCCACCCGAACTTCCTGAAGAAACAGCTGGTTCCCGGTAGGCAGGGGATCTTCATCGGCGACGT
CGCCCAGTTCGGCTTCCAGCGCGAGATGCACCATCCCGAGGTCGAGTGGGCCGCGGAGGGTGAGGACCTCTCCCAGGTGA
TGGCGCGCGACCCCGACAACTTCGGCAGCATACTTCCGGTCTATCCGCTCACCGAGGGGGTGAGCCAGAAGGTGATGCGC
CGCATCATGCGCGACGCCGTGCAGCGTTACAGCCGCTACGTGAAGGGGGCGCTTCCCGACGAGCTTCTGCAGCGCCACAA
GCTCCTCACGCTTCCCGTGGCGCTACGCGAGGCGCACCTTCCTGCCCAGGACAGCGACCTTTCCGCGCTCAACAGCGGCC
GCAGCTCGGCACACCGCTCACTCGCTTTCGACGAGCTCTTCTTCCTGCAGTTGGGGCTCGCCCTTAAAAGGCGCGGCATC
GCGGTAGAGGACGGCATCAGCTTCAAGGTGACCCACCGCTACACCAAGGAACTCCTAAAGCTCCTCCCCTTCAGCCTGAC
CGCTGCTCAGAAACGGGTACTCTCCGAGATAAAGGAAGACATGATGTCGCCCCACCCGATGCACAGGCTGGTGCAGGGGG
ATGTGGGCTGCGGCAAGACGCTCGTCGCCCTCATGGCCGCGCTCGTCTGCGTGGAAAACGATTACCAGGTCGCCATCATG
GCCCCCACCGAGCTTCTAGCCGAACAGCACTACCTGAACATCCATGGCTACTGCGAGAAACTGGGCATAGGCGTGACGCT
CCTGACTGCGAGCGTGAAGGGGAAGGGTGACACGCTGGAAAAAATTGCCTCCGGCGCCACCCAGATCGTGGTCGGGACTC
ACGCCGTCATCCAGGAGAAGGTGGAATTCCACCGATTGGGGCTGGGAATCATCGACGAGCAGCACCGCTTCGGCGTCGTG
CAGCGCGCCCAGTTGAAGAAGAAGGGGGCGAACCCCGACATCCTGGTGATGACGGCGACTCCCATTCCGCGCACTCTTTC
CATGACCGTCTTCGGAGACCTCTCGCTTTCGGTGATCGACGAGTTGCCGCCGGGGAGGACCCCCATCGAGACGCGGATGG
TGCGCGAGTCGCGCCGCAAGGAGGTGTACGCGCTGGTGAGGGAGGAGGCGGCGAAGGGGAGGCAGGCCTACGTCATCTAT
CCCCTGGTCGAGGAGACCGAGAAGAGCGACCTGAAGGCTGCAGTGCAAATGGCCGAGCACCTGGCGCAGGATGTTTTTCC
GGACCTGCGCGTCGCCGTCCTCCACGGGCGCATGCCCGCCGCCGAGAAGGAAGCGGTGATGAAGGAGTTCAAGGCGGGGA
CTACCGACATCCTGGTCGCCACCACGGTCATCGAGGTCGGCATCGACGTCCCCAACGCCACCGTAATGGTCATCGAACAC
GCCGAGCGGTTCGGTCTTTCCCAACTGCACCAGTTGCGGGGGAGGGTGGGGCGCGGCAGCGAGCGCTCCCGCTGCATCCT
GCTCGCCGGGGACAAGCTCTCCGAGGACGGCCAGAAACGTCTTGAGGTAATGGTGCAGAGCTCCGACGGCTTCGTCATCG
CCGAGGCCGACCTTCAGATCAGGGGACCCGGCGACTTCCTGGGCACCAGGCAGGCGGGGCTTCCCGAATTGCGGGTGGCG
GACATCCTGCGGGACGGCGGCGTGCTGGAGCAGGCGCGCAAAGACGCCTTCGCCCTGGTCGAGCGCGACCCGGAGCTGTC
CGCGCCCGGACACGAACGTCTGCGCGGGGAAATGATGCTCCGCTGGGGCGGGAGGTTGGAGCTCGCCAGCATCGGGTGA

Upstream 100 bases:

>100_bases
CAGCGTGGACGAGATCGTCGCCGACATCAACAAGCTTTTCTAGCAGTTTCCGCTGCCTGGCGCGGTTTTCCCGCGCCAGG
CGCTCTTACCCTCTCTCCCC

Downstream 100 bases:

>100_bases
CTCGCTGAATTCGGTCGAGTCCTGTAACACTAGGTCGATTTTCCGAACAACTCGGTCAAGTCCTCGAACAACCTGATCAA
GTCCTCGAACAACTTAGGCA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 771

Protein sequence:

>772_residues
MPTITLAPDGSIPLPEQLRNDLKLRPGDLVSVEVVDGTLRISKQKSAKETRSTPPAAKPAAAVAQVTVPEELKTPMQSIK
GVGPKLAATLSKKGLDTVEDALYLLPNRYEDRRELKKIAQLRPGNSEAFFATVVSAAAQTTKGGRRYFEAIVKDETGSLP
LKWFHFHPNFLKKQLVPGRQGIFIGDVAQFGFQREMHHPEVEWAAEGEDLSQVMARDPDNFGSILPVYPLTEGVSQKVMR
RIMRDAVQRYSRYVKGALPDELLQRHKLLTLPVALREAHLPAQDSDLSALNSGRSSAHRSLAFDELFFLQLGLALKRRGI
AVEDGISFKVTHRYTKELLKLLPFSLTAAQKRVLSEIKEDMMSPHPMHRLVQGDVGCGKTLVALMAALVCVENDYQVAIM
APTELLAEQHYLNIHGYCEKLGIGVTLLTASVKGKGDTLEKIASGATQIVVGTHAVIQEKVEFHRLGLGIIDEQHRFGVV
QRAQLKKKGANPDILVMTATPIPRTLSMTVFGDLSLSVIDELPPGRTPIETRMVRESRRKEVYALVREEAAKGRQAYVIY
PLVEETEKSDLKAAVQMAEHLAQDVFPDLRVAVLHGRMPAAEKEAVMKEFKAGTTDILVATTVIEVGIDVPNATVMVIEH
AERFGLSQLHQLRGRVGRGSERSRCILLAGDKLSEDGQKRLEVMVQSSDGFVIAEADLQIRGPGDFLGTRQAGLPELRVA
DILRDGGVLEQARKDAFALVERDPELSAPGHERLRGEMMLRWGGRLELASIG

Sequences:

>Translated_772_residues
MPTITLAPDGSIPLPEQLRNDLKLRPGDLVSVEVVDGTLRISKQKSAKETRSTPPAAKPAAAVAQVTVPEELKTPMQSIK
GVGPKLAATLSKKGLDTVEDALYLLPNRYEDRRELKKIAQLRPGNSEAFFATVVSAAAQTTKGGRRYFEAIVKDETGSLP
LKWFHFHPNFLKKQLVPGRQGIFIGDVAQFGFQREMHHPEVEWAAEGEDLSQVMARDPDNFGSILPVYPLTEGVSQKVMR
RIMRDAVQRYSRYVKGALPDELLQRHKLLTLPVALREAHLPAQDSDLSALNSGRSSAHRSLAFDELFFLQLGLALKRRGI
AVEDGISFKVTHRYTKELLKLLPFSLTAAQKRVLSEIKEDMMSPHPMHRLVQGDVGCGKTLVALMAALVCVENDYQVAIM
APTELLAEQHYLNIHGYCEKLGIGVTLLTASVKGKGDTLEKIASGATQIVVGTHAVIQEKVEFHRLGLGIIDEQHRFGVV
QRAQLKKKGANPDILVMTATPIPRTLSMTVFGDLSLSVIDELPPGRTPIETRMVRESRRKEVYALVREEAAKGRQAYVIY
PLVEETEKSDLKAAVQMAEHLAQDVFPDLRVAVLHGRMPAAEKEAVMKEFKAGTTDILVATTVIEVGIDVPNATVMVIEH
AERFGLSQLHQLRGRVGRGSERSRCILLAGDKLSEDGQKRLEVMVQSSDGFVIAEADLQIRGPGDFLGTRQAGLPELRVA
DILRDGGVLEQARKDAFALVERDPELSAPGHERLRGEMMLRWGGRLELASIG
>Mature_771_residues
PTITLAPDGSIPLPEQLRNDLKLRPGDLVSVEVVDGTLRISKQKSAKETRSTPPAAKPAAAVAQVTVPEELKTPMQSIKG
VGPKLAATLSKKGLDTVEDALYLLPNRYEDRRELKKIAQLRPGNSEAFFATVVSAAAQTTKGGRRYFEAIVKDETGSLPL
KWFHFHPNFLKKQLVPGRQGIFIGDVAQFGFQREMHHPEVEWAAEGEDLSQVMARDPDNFGSILPVYPLTEGVSQKVMRR
IMRDAVQRYSRYVKGALPDELLQRHKLLTLPVALREAHLPAQDSDLSALNSGRSSAHRSLAFDELFFLQLGLALKRRGIA
VEDGISFKVTHRYTKELLKLLPFSLTAAQKRVLSEIKEDMMSPHPMHRLVQGDVGCGKTLVALMAALVCVENDYQVAIMA
PTELLAEQHYLNIHGYCEKLGIGVTLLTASVKGKGDTLEKIASGATQIVVGTHAVIQEKVEFHRLGLGIIDEQHRFGVVQ
RAQLKKKGANPDILVMTATPIPRTLSMTVFGDLSLSVIDELPPGRTPIETRMVRESRRKEVYALVREEAAKGRQAYVIYP
LVEETEKSDLKAAVQMAEHLAQDVFPDLRVAVLHGRMPAAEKEAVMKEFKAGTTDILVATTVIEVGIDVPNATVMVIEHA
ERFGLSQLHQLRGRVGRGSERSRCILLAGDKLSEDGQKRLEVMVQSSDGFVIAEADLQIRGPGDFLGTRQAGLPELRVAD
ILRDGGVLEQARKDAFALVERDPELSAPGHERLRGEMMLRWGGRLELASIG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=681, Percent_Identity=45.8149779735683, Blast_Score=506, Evalue=1e-144,
Organism=Escherichia coli, GI1787357, Length=400, Percent_Identity=41, Blast_Score=281, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 85080; Mature: 84948

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTITLAPDGSIPLPEQLRNDLKLRPGDLVSVEVVDGTLRISKQKSAKETRSTPPAAKPA
CCEEEECCCCCCCCHHHHHHCCCCCCCCEEEEEEECCEEEECCHHHHHHHCCCCCCCCCH
AAVAQVTVPEELKTPMQSIKGVGPKLAATLSKKGLDTVEDALYLLPNRYEDRRELKKIAQ
HHHEEEECCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHH
LRPGNSEAFFATVVSAAAQTTKGGRRYFEAIVKDETGSLPLKWFHFHPNFLKKQLVPGRQ
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCC
GIFIGDVAQFGFQREMHHPEVEWAAEGEDLSQVMARDPDNFGSILPVYPLTEGVSQKVMR
CEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHH
RIMRDAVQRYSRYVKGALPDELLQRHKLLTLPVALREAHLPAQDSDLSALNSGRSSAHRS
HHHHHHHHHHHHHHCCCCCHHHHHHCCEEEHHHHHHHHCCCCCCCCHHHHHCCHHHHHHH
LAFDELFFLQLGLALKRRGIAVEDGISFKVTHRYTKELLKLLPFSLTAAQKRVLSEIKED
HHHHHHHHHHHHHHHHHCCCEEECCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MMSPHPMHRLVQGDVGCGKTLVALMAALVCVENDYQVAIMAPTELLAEQHYLNIHGYCEK
HCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHEEEHHHHHHH
LGIGVTLLTASVKGKGDTLEKIASGATQIVVGTHAVIQEKVEFHRLGLGIIDEQHRFGVV
HCCCEEEEEEECCCCCHHHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCEECCHHHHHHH
QRAQLKKKGANPDILVMTATPIPRTLSMTVFGDLSLSVIDELPPGRTPIETRMVRESRRK
HHHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHH
EVYALVREEAAKGRQAYVIYPLVEETEKSDLKAAVQMAEHLAQDVFPDLRVAVLHGRMPA
HHHHHHHHHHHCCCEEEEEEEEHHCCCHHHHHHHHHHHHHHHHHCCCHHEEHHHCCCCCC
AEKEAVMKEFKAGTTDILVATTVIEVGIDVPNATVMVIEHAERFGLSQLHQLRGRVGRGS
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCC
ERSRCILLAGDKLSEDGQKRLEVMVQSSDGFVIAEADLQIRGPGDFLGTRQAGLPELRVA
CCCEEEEEECCCCCCCHHHHHHEEEECCCCEEEEECCEEEECCCCCCCCCCCCCCCHHHH
DILRDGGVLEQARKDAFALVERDPELSAPGHERLRGEMMLRWGGRLELASIG
HHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEECCEEEEECCC
>Mature Secondary Structure 
PTITLAPDGSIPLPEQLRNDLKLRPGDLVSVEVVDGTLRISKQKSAKETRSTPPAAKPA
CEEEECCCCCCCCHHHHHHCCCCCCCCEEEEEEECCEEEECCHHHHHHHCCCCCCCCCH
AAVAQVTVPEELKTPMQSIKGVGPKLAATLSKKGLDTVEDALYLLPNRYEDRRELKKIAQ
HHHEEEECCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHH
LRPGNSEAFFATVVSAAAQTTKGGRRYFEAIVKDETGSLPLKWFHFHPNFLKKQLVPGRQ
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCC
GIFIGDVAQFGFQREMHHPEVEWAAEGEDLSQVMARDPDNFGSILPVYPLTEGVSQKVMR
CEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHH
RIMRDAVQRYSRYVKGALPDELLQRHKLLTLPVALREAHLPAQDSDLSALNSGRSSAHRS
HHHHHHHHHHHHHHCCCCCHHHHHHCCEEEHHHHHHHHCCCCCCCCHHHHHCCHHHHHHH
LAFDELFFLQLGLALKRRGIAVEDGISFKVTHRYTKELLKLLPFSLTAAQKRVLSEIKED
HHHHHHHHHHHHHHHHHCCCEEECCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MMSPHPMHRLVQGDVGCGKTLVALMAALVCVENDYQVAIMAPTELLAEQHYLNIHGYCEK
HCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHEEEHHHHHHH
LGIGVTLLTASVKGKGDTLEKIASGATQIVVGTHAVIQEKVEFHRLGLGIIDEQHRFGVV
HCCCEEEEEEECCCCCHHHHHHHCCCEEEEECHHHHHHHHHHHHHHCCCEECCHHHHHHH
QRAQLKKKGANPDILVMTATPIPRTLSMTVFGDLSLSVIDELPPGRTPIETRMVRESRRK
HHHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHH
EVYALVREEAAKGRQAYVIYPLVEETEKSDLKAAVQMAEHLAQDVFPDLRVAVLHGRMPA
HHHHHHHHHHHCCCEEEEEEEEHHCCCHHHHHHHHHHHHHHHHHCCCHHEEHHHCCCCCC
AEKEAVMKEFKAGTTDILVATTVIEVGIDVPNATVMVIEHAERFGLSQLHQLRGRVGRGS
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCC
ERSRCILLAGDKLSEDGQKRLEVMVQSSDGFVIAEADLQIRGPGDFLGTRQAGLPELRVA
CCCEEEEEECCCCCCCHHHHHHEEEECCCCEEEEECCEEEECCCCCCCCCCCCCCCHHHH
DILRDGGVLEQARKDAFALVERDPELSAPGHERLRGEMMLRWGGRLELASIG
HHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEECCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]