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The map label for this gene is regX3 [H]

Identifier: 197118229

GI number: 197118229

Start: 2139989

End: 2140669

Strand: Reverse

Name: regX3 [H]

Synonym: Gbem_1846

Alternate gene names: 197118229

Gene position: 2140669-2139989 (Counterclockwise)

Preceding gene: 197118230

Following gene: 197118228

Centisome position: 46.38

GC content: 55.21

Gene sequence:

>681_bases
ATGGAGACCATATTGATCATCGAAGACGAGAGGGACCTAGCGGAGCTTCTTGCCTTTAACCTGGAGAGAGAGGGGTACAA
GACAATAATAGCGGCCGACGGCATTGAAGGATTGGCAAACGCCGGTCACTGCCATCCAGACCTCATCATCCTCGACCTCA
TGCTCCCCGGCATGCTGGGCACGGAAGTTTGCAAGAACCTCAAGAAATCGGAAAGAACCGCTGGCATCCCGGTGATCATG
CTCACTGCCAAAGGGGAGGAGATCGATAAGGTGGTGGGATTCGAGGTCGGAGCGGACGACTACGTTGTCAAGCCGTTCTC
GAGCAGGGAATTGAACCTGCGCGTGAAAGCCGTACTCAGACGCAGCAATACCGAGACCGTCTCCAGCACGATGATCGAGT
TGGGCCCCATCACCATTGATACCGACCGTCATCAAGTCATGGTGAACGGAGAGGAGATCTTCTTCACCAGCACCGAATTC
AAGCTGCTGCATGTTCTGGCGCAGAGACTGGGAAGGGTGCAAAGCCGTGACGTTTTGTTGCGGGATGTGTGGGGCTACAA
CTTCGTGGACGACAGCCGAACCGTCGATACCCATATAACACGCTTGCGCACCAAGATGGGGGCGGCTGGCGATCTGATCA
AGACCGTGCGCGGTTTCGGCTATAAGCTCGAAGTGCAATGA

Upstream 100 bases:

>100_bases
GGACGAGCAGTTTTGAGCCGCGCAGAGATTTAACCATTCTGTAACAGGTTCTACACAAAAGATGTGTATGAAAGGTACAA
ACGGTACCAGAGGGAGTGGC

Downstream 100 bases:

>100_bases
CACCTGAAGCCTAGACACAACGCGGACCGGCTGACCAGCGTAGAAAAATGTATTGAACACATCCGGCCCAACTAATATAG
TCCCGTCCCCCCATGAAAGA

Product: winged-helix transcriptional response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
METILIIEDERDLAELLAFNLEREGYKTIIAADGIEGLANAGHCHPDLIILDLMLPGMLGTEVCKNLKKSERTAGIPVIM
LTAKGEEIDKVVGFEVGADDYVVKPFSSRELNLRVKAVLRRSNTETVSSTMIELGPITIDTDRHQVMVNGEEIFFTSTEF
KLLHVLAQRLGRVQSRDVLLRDVWGYNFVDDSRTVDTHITRLRTKMGAAGDLIKTVRGFGYKLEVQ

Sequences:

>Translated_226_residues
METILIIEDERDLAELLAFNLEREGYKTIIAADGIEGLANAGHCHPDLIILDLMLPGMLGTEVCKNLKKSERTAGIPVIM
LTAKGEEIDKVVGFEVGADDYVVKPFSSRELNLRVKAVLRRSNTETVSSTMIELGPITIDTDRHQVMVNGEEIFFTSTEF
KLLHVLAQRLGRVQSRDVLLRDVWGYNFVDDSRTVDTHITRLRTKMGAAGDLIKTVRGFGYKLEVQ
>Mature_226_residues
METILIIEDERDLAELLAFNLEREGYKTIIAADGIEGLANAGHCHPDLIILDLMLPGMLGTEVCKNLKKSERTAGIPVIM
LTAKGEEIDKVVGFEVGADDYVVKPFSSRELNLRVKAVLRRSNTETVSSTMIELGPITIDTDRHQVMVNGEEIFFTSTEF
KLLHVLAQRLGRVQSRDVLLRDVWGYNFVDDSRTVDTHITRLRTKMGAAGDLIKTVRGFGYKLEVQ

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=44.5945945945946, Blast_Score=186, Evalue=8e-49,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=40.4444444444444, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=39.5555555555556, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=40.6926406926407, Blast_Score=148, Evalue=2e-37,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=40.5405405405405, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=37.8378378378378, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=37.5, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=35.3982300884956, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=35.0877192982456, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=32.2727272727273, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=32.1739130434783, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=31.5555555555556, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=30.3418803418803, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=34.5132743362832, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=36.4406779661017, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25276; Mature: 25276

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METILIIEDERDLAELLAFNLEREGYKTIIAADGIEGLANAGHCHPDLIILDLMLPGMLG
CCEEEEEECCHHHHHHHHHCCCCCCCEEEEEECCCHHHCCCCCCCCHHEEEEHHCCCHHH
TEVCKNLKKSERTAGIPVIMLTAKGEEIDKVVGFEVGADDYVVKPFSSRELNLRVKAVLR
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCEEECCCCEEECCCCCCCEEEEEEEEHH
RSNTETVSSTMIELGPITIDTDRHQVMVNGEEIFFTSTEFKLLHVLAQRLGRVQSRDVLL
CCCCHHHHHHHHEECCEEEECCCCEEEECCCEEEEECCHHHHHHHHHHHHCCCCCCCCCE
RDVWGYNFVDDSRTVDTHITRLRTKMGAAGDLIKTVRGFGYKLEVQ
EHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
METILIIEDERDLAELLAFNLEREGYKTIIAADGIEGLANAGHCHPDLIILDLMLPGMLG
CCEEEEEECCHHHHHHHHHCCCCCCCEEEEEECCCHHHCCCCCCCCHHEEEEHHCCCHHH
TEVCKNLKKSERTAGIPVIMLTAKGEEIDKVVGFEVGADDYVVKPFSSRELNLRVKAVLR
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCEEECCCCEEECCCCCCCEEEEEEEEHH
RSNTETVSSTMIELGPITIDTDRHQVMVNGEEIFFTSTEFKLLHVLAQRLGRVQSRDVLL
CCCCHHHHHHHHEECCEEEECCCCEEEECCCEEEEECCHHHHHHHHHHHHCCCCCCCCCE
RDVWGYNFVDDSRTVDTHITRLRTKMGAAGDLIKTVRGFGYKLEVQ
EHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA