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The map label for this gene is arsR [H]

Identifier: 197118228

GI number: 197118228

Start: 2139480

End: 2139896

Strand: Reverse

Name: arsR [H]

Synonym: Gbem_1845

Alternate gene names: 197118228

Gene position: 2139896-2139480 (Counterclockwise)

Preceding gene: 197118229

Following gene: 197118226

Centisome position: 46.37

GC content: 58.51

Gene sequence:

>417_bases
ATGAAAGACATCCTGCAGCTCTACAAATCGCTGTCCGACGAGACCCGTCTGCGCATCCTGGCGCTGCTTCTTGCCGAGGG
GGAACTCTGCGTCTGCGACATCATCGCCACGCTGAAGCTTCCGCAATCCACCATCTCGCGCCAACTCGCCATTCTGAGGA
AAACGGGCTGGGTGAATGACCGTCGCAGCGGTCTCTGGATCTACTACTCGATCAGAGAAAACCAGGGGCGCCAGCAGGAG
CTTATCTCGACTCTGAAGCAGCAGCTCCTTGGAACCAAGGCATCGGTCGCGGACCGTGAAGTCTTGGCCCGCTTTGGCCG
CGGCGAAGGAAGCGAGGAGGAGGTGCTACCGCATTACCGCCGCGTACGCGATGAAATAAAGGCCTGGATCATGGAAACGT
TCGGAGGCAACAAGTGA

Upstream 100 bases:

>100_bases
TGCAATGACACCTGAAGCCTAGACACAACGCGGACCGGCTGACCAGCGTAGAAAAATGTATTGAACACATCCGGCCCAAC
TAATATAGTCCCGTCCCCCC

Downstream 100 bases:

>100_bases
GCGAGCATCTCTCCCGCAATCTCTCTTTTCTGGACCGCTGGCTGACCCTATGGATCTTCGCCGCGATGCTGGCCGTGCTC
CTGCTCCCCGACAAGCCCGA

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKDILQLYKSLSDETRLRILALLLAEGELCVCDIIATLKLPQSTISRQLAILRKTGWVNDRRSGLWIYYSIRENQGRQQE
LISTLKQQLLGTKASVADREVLARFGRGEGSEEEVLPHYRRVRDEIKAWIMETFGGNK

Sequences:

>Translated_138_residues
MKDILQLYKSLSDETRLRILALLLAEGELCVCDIIATLKLPQSTISRQLAILRKTGWVNDRRSGLWIYYSIRENQGRQQE
LISTLKQQLLGTKASVADREVLARFGRGEGSEEEVLPHYRRVRDEIKAWIMETFGGNK
>Mature_138_residues
MKDILQLYKSLSDETRLRILALLLAEGELCVCDIIATLKLPQSTISRQLAILRKTGWVNDRRSGLWIYYSIRENQGRQQE
LISTLKQQLLGTKASVADREVLARFGRGEGSEEEVLPHYRRVRDEIKAWIMETFGGNK

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=70, Percent_Identity=48.5714285714286, Blast_Score=70, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 15877; Mature: 15877

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDILQLYKSLSDETRLRILALLLAEGELCVCDIIATLKLPQSTISRQLAILRKTGWVND
CHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
RRSGLWIYYSIRENQGRQQELISTLKQQLLGTKASVADREVLARFGRGEGSEEEVLPHYR
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
RVRDEIKAWIMETFGGNK
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKDILQLYKSLSDETRLRILALLLAEGELCVCDIIATLKLPQSTISRQLAILRKTGWVND
CHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
RRSGLWIYYSIRENQGRQQELISTLKQQLLGTKASVADREVLARFGRGEGSEEEVLPHYR
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
RVRDEIKAWIMETFGGNK
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2408017; 1838573; 8416957 [H]