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The map label for this gene is 197118085

Identifier: 197118085

GI number: 197118085

Start: 1963334

End: 1964608

Strand: Direct

Name: 197118085

Synonym: Gbem_1699

Alternate gene names: NA

Gene position: 1963334-1964608 (Clockwise)

Preceding gene: 197118084

Following gene: 197118086

Centisome position: 42.54

GC content: 64.16

Gene sequence:

>1275_bases
ATGCGAGTCCTGTTGATTTCCGCGAATACTGAAACCATGAACATGGTGCCGCTCCCGTTGGGGCTCAACTGCGTGGCCGT
CGCCACCGGTAACGCGGGTCACGAGGTGCGACTGCTCGACCTGATGGGGGGAGGCGACAACGACTCGCTCATCCGGGCCG
CCATCGATACTTTCCGTCCGGAGGTGATCGGCATCTCGGTCCGTAATGTGGACAACCAGAGCATGGCGGACACCAAGTTC
CTCCTGGAGCCGGTAAGGGAAACGGTCGCCCTTTGCAGGAGCTTGTCCTATGCGCCGACGGTCGTGGGCGGCGCCGCTTT
CAGCATCTTCCCCGCGGCGATGCTGGATTACCTCGGCGCCGACATGGGTATCTGCGGCGAAGGGGAGCTGGCCTTCACGG
AGCTTGTCGACGCCCTGCAGCGGGGAGGGGAACTTTCCGGCATTGCCGGCCTTTGCCTCCCGGGAAAGCCGGTGCAGATG
GGCTCGGCCGCGAGGGGGGGCTTGGAAGGGCTTCCTTTTCCGGACCCTTCCCTTTGGTCGGTTCCGGCGGGGCGGGCGGA
CGAGCTCTGGATCCCGCTGCAGACCAGGCGCGGCTGCCCGATGCGTTGCAGCTACTGCTCCACCCCCGCCCTGGAGGGGA
CGGCGATCAGGATGCATCCGGTCGAGACCGTCTTGGAAGCGCTCTCCCGCCATGTCGCCGCCGGGTTCAATAACTTCTAC
TTTGTCGACAACACCTTCAACTTTCCCCCCGACTACGCGAAGCGCCTGTGCGACGCCATCGTCTCTGCCCAACTCGGCAT
CCGCTGGCGCTGCATCCTCTATCCCGGATTCGTGGACGAGGAGATGGTCTCCAAGATGGCCCGCGCCGGCTGCGTCGAGG
TGAGCCTCGGGTTCGAGAGCGGGTCGTCCCTCATCCTGAAAAACCTCAACAAGAAGTACGACCTTGACCGGGTCCGCGAT
GCTTCCGAACTCCTCCGGCGCCACGGCATCGCCAGGATGGGGTTCCTCATGTTCGGCGCGCCCGGTGAAACCAGGGAGAC
GGTGCAGGAAAGCCTCGACTTCGCCGATTCCCTGCAGCTAGACATGCTGAAGCTCTCCACCGGGATCCGCATCTACCCCG
ACACGCCTCTAGCCGAGACGGCCAGAAGGGAAGGGGTGATCGCCGGGGATGACGACCTGCTCCTTCCCCGCTTCTATCAG
GCTCCGGGCCTGGATGAGTGGCTTGGGCCGCTGCTGGCTGACTGGATGAAGACCCGCCCCTACTGTATCAGCTAG

Upstream 100 bases:

>100_bases
CGACTGCAAGATCGACGGCATCGGCGCGATGCAGCTCAAATCTGAGTTCGTGAAGAAGGCCTGATTGTAAAGTAGAGCGA
AGATTTTGGAGGAGCAGCAT

Downstream 100 bases:

>100_bases
CGGGTTTTAGGTAGAAAAGACTTGGGTAGAAGCGATTCTTTGGCTATACTGCCTGGCTTTCCTACCGCAATGATTGAAAA
GGAACTTGAATGGATTGGTT

Product: cobalamin-binding radical SAM domain-containing iron-sulfur cluster-binding oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MRVLLISANTETMNMVPLPLGLNCVAVATGNAGHEVRLLDLMGGGDNDSLIRAAIDTFRPEVIGISVRNVDNQSMADTKF
LLEPVRETVALCRSLSYAPTVVGGAAFSIFPAAMLDYLGADMGICGEGELAFTELVDALQRGGELSGIAGLCLPGKPVQM
GSAARGGLEGLPFPDPSLWSVPAGRADELWIPLQTRRGCPMRCSYCSTPALEGTAIRMHPVETVLEALSRHVAAGFNNFY
FVDNTFNFPPDYAKRLCDAIVSAQLGIRWRCILYPGFVDEEMVSKMARAGCVEVSLGFESGSSLILKNLNKKYDLDRVRD
ASELLRRHGIARMGFLMFGAPGETRETVQESLDFADSLQLDMLKLSTGIRIYPDTPLAETARREGVIAGDDDLLLPRFYQ
APGLDEWLGPLLADWMKTRPYCIS

Sequences:

>Translated_424_residues
MRVLLISANTETMNMVPLPLGLNCVAVATGNAGHEVRLLDLMGGGDNDSLIRAAIDTFRPEVIGISVRNVDNQSMADTKF
LLEPVRETVALCRSLSYAPTVVGGAAFSIFPAAMLDYLGADMGICGEGELAFTELVDALQRGGELSGIAGLCLPGKPVQM
GSAARGGLEGLPFPDPSLWSVPAGRADELWIPLQTRRGCPMRCSYCSTPALEGTAIRMHPVETVLEALSRHVAAGFNNFY
FVDNTFNFPPDYAKRLCDAIVSAQLGIRWRCILYPGFVDEEMVSKMARAGCVEVSLGFESGSSLILKNLNKKYDLDRVRD
ASELLRRHGIARMGFLMFGAPGETRETVQESLDFADSLQLDMLKLSTGIRIYPDTPLAETARREGVIAGDDDLLLPRFYQ
APGLDEWLGPLLADWMKTRPYCIS
>Mature_424_residues
MRVLLISANTETMNMVPLPLGLNCVAVATGNAGHEVRLLDLMGGGDNDSLIRAAIDTFRPEVIGISVRNVDNQSMADTKF
LLEPVRETVALCRSLSYAPTVVGGAAFSIFPAAMLDYLGADMGICGEGELAFTELVDALQRGGELSGIAGLCLPGKPVQM
GSAARGGLEGLPFPDPSLWSVPAGRADELWIPLQTRRGCPMRCSYCSTPALEGTAIRMHPVETVLEALSRHVAAGFNNFY
FVDNTFNFPPDYAKRLCDAIVSAQLGIRWRCILYPGFVDEEMVSKMARAGCVEVSLGFESGSSLILKNLNKKYDLDRVRD
ASELLRRHGIARMGFLMFGAPGETRETVQESLDFADSLQLDMLKLSTGIRIYPDTPLAETARREGVIAGDDDLLLPRFYQ
APGLDEWLGPLLADWMKTRPYCIS

Specific function: Unknown

COG id: COG1032

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR007197 [H]

Pfam domain/function: PF02310 B12-binding; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 46121; Mature: 46121

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLISANTETMNMVPLPLGLNCVAVATGNAGHEVRLLDLMGGGDNDSLIRAAIDTFRP
CEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCC
EVIGISVRNVDNQSMADTKFLLEPVRETVALCRSLSYAPTVVGGAAFSIFPAAMLDYLGA
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCC
DMGICGEGELAFTELVDALQRGGELSGIAGLCLPGKPVQMGSAARGGLEGLPFPDPSLWS
CCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
VPAGRADELWIPLQTRRGCPMRCSYCSTPALEGTAIRMHPVETVLEALSRHVAAGFNNFY
CCCCCCCCEEEEHHCCCCCCCEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCEE
FVDNTFNFPPDYAKRLCDAIVSAQLGIRWRCILYPGFVDEEMVSKMARAGCVEVSLGFES
EEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCC
GSSLILKNLNKKYDLDRVRDASELLRRHGIARMGFLMFGAPGETRETVQESLDFADSLQL
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHEEECCCCCHHHHHHHHHCHHHHHHH
DMLKLSTGIRIYPDTPLAETARREGVIAGDDDLLLPRFYQAPGLDEWLGPLLADWMKTRP
HHEECCCCCEECCCCCHHHHHHHCCCEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCC
YCIS
CCCC
>Mature Secondary Structure
MRVLLISANTETMNMVPLPLGLNCVAVATGNAGHEVRLLDLMGGGDNDSLIRAAIDTFRP
CEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCC
EVIGISVRNVDNQSMADTKFLLEPVRETVALCRSLSYAPTVVGGAAFSIFPAAMLDYLGA
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCC
DMGICGEGELAFTELVDALQRGGELSGIAGLCLPGKPVQMGSAARGGLEGLPFPDPSLWS
CCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
VPAGRADELWIPLQTRRGCPMRCSYCSTPALEGTAIRMHPVETVLEALSRHVAAGFNNFY
CCCCCCCCEEEEHHCCCCCCCEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCEE
FVDNTFNFPPDYAKRLCDAIVSAQLGIRWRCILYPGFVDEEMVSKMARAGCVEVSLGFES
EEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCC
GSSLILKNLNKKYDLDRVRDASELLRRHGIARMGFLMFGAPGETRETVQESLDFADSLQL
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHEEECCCCCHHHHHHHHHCHHHHHHH
DMLKLSTGIRIYPDTPLAETARREGVIAGDDDLLLPRFYQAPGLDEWLGPLLADWMKTRP
HHEECCCCCEECCCCCHHHHHHHCCCEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCC
YCIS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]