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The map label for this gene is cheB-2 [H]

Identifier: 197117984

GI number: 197117984

Start: 1850880

End: 1851950

Strand: Direct

Name: cheB-2 [H]

Synonym: Gbem_1597

Alternate gene names: 197117984

Gene position: 1850880-1851950 (Clockwise)

Preceding gene: 197117983

Following gene: 197117985

Centisome position: 40.1

GC content: 64.05

Gene sequence:

>1071_bases
ATGGTGAAGAAGAAGATAAAAGTGCTTATAGTGGACGATTCGGCGGTGGTGCGTCAGACCCTGTCGGAGATCCTCTCCTC
CGATCCCCAGATCGAGGTGATGTCGACGGCCGGCGATCCCTTCATCGCGGCGGAGCGCATCAGGCACGAGGTCCCCGATG
TCATCACCCTCGACGTCGAGATGCCGCGCATGGACGGCATCACTTTCCTGCACAAGATCATGAGCCAGCATCCTATCCCG
GTGGTGATGTGCTCAAGCCTCACCGAGATGGGGTCGGAGACCGCGTTAAAGGCGCTTGAGTACGGGGCGGTGGAGATCAT
CCAGAAGCCGCGCCTTGGGACCAAGACCTTCCTCGAGGAGTCCAGGGTGAGGATCTGCGACGTGGTGAAGGCGGCGAGCC
AGGCGAGGGTCAGGAAGGTGTCGGCGGCCCCGCACCAGGTAGCCCCGAAGCTTTCCGCCGACGTCATCATGGAGAAGCCC
AAGAGCCAGGCTATGATGCAGACCACGGAAAAAGTGGTCGTAATAGGCGCCTCCACCGGCGGCACCGAGGCGCTGCGCAC
CTTCCTGGAGTCGCTGCCGGCCGACTCTCCCGGCATCGTCATCGTGCAGCACATGCCGGAAGGTTTCACCCGCGCCTTTT
CGCAGCGGCTGGACGGGCTTTGCCGGATCACGGTCAAGGAGGCGGAGAACAACGACACCGTGGTGCGAGGCCGGGCGCTG
ATCGCTGCCGGGAACCACCATCTCCTTTTGAAAAGAAGCGGCGCCCGCTACTACGTCGAGATCAAGGACGGGCCGCTGGT
CTCGCGGCACCGCCCCTCCGTGGACGTGCTTTTCAGGTCCGCCGCGCGTTACGCCGGCAAGAACGCCGTCGGCGTCATCA
TGACGGGGATGGGGGACGACGGCGCGCACGGCATGCTGGAGATGAAGCAGGCCGGTGCCGTGAACATCGCCCAGGACGAG
GCGAGCTGCATCGTCTTCGGCATGCCCAACGAGGCGATCAAGCTGGGGGGGGTCGACCTGGTGCGTCCCCTCGACGCCAT
CAGCCGCGAAGTCCTGAGGCTTTGCGCGTGA

Upstream 100 bases:

>100_bases
GCGCCAGGACCTGGGGGGAGAGCGGGGAAGAAAGATCATCTTTCATACCGATACGGGAGAGGTGCTTTTACAACGGCTCG
GTAAATCGGGGGTTTCATAG

Downstream 100 bases:

>100_bases
ACGTTGAACGTTGAACAGCTTTTTCGGGGATATCCATGAGCGAAGAAAAATTCTTTCTCGGACGACAGCCGATACTCGAC
CGGACCCAGAAGATAGTCGG

Product: response receiver chemotaxis protein-glutamate methylesterase CheB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MVKKKIKVLIVDDSAVVRQTLSEILSSDPQIEVMSTAGDPFIAAERIRHEVPDVITLDVEMPRMDGITFLHKIMSQHPIP
VVMCSSLTEMGSETALKALEYGAVEIIQKPRLGTKTFLEESRVRICDVVKAASQARVRKVSAAPHQVAPKLSADVIMEKP
KSQAMMQTTEKVVVIGASTGGTEALRTFLESLPADSPGIVIVQHMPEGFTRAFSQRLDGLCRITVKEAENNDTVVRGRAL
IAAGNHHLLLKRSGARYYVEIKDGPLVSRHRPSVDVLFRSAARYAGKNAVGVIMTGMGDDGAHGMLEMKQAGAVNIAQDE
ASCIVFGMPNEAIKLGGVDLVRPLDAISREVLRLCA

Sequences:

>Translated_356_residues
MVKKKIKVLIVDDSAVVRQTLSEILSSDPQIEVMSTAGDPFIAAERIRHEVPDVITLDVEMPRMDGITFLHKIMSQHPIP
VVMCSSLTEMGSETALKALEYGAVEIIQKPRLGTKTFLEESRVRICDVVKAASQARVRKVSAAPHQVAPKLSADVIMEKP
KSQAMMQTTEKVVVIGASTGGTEALRTFLESLPADSPGIVIVQHMPEGFTRAFSQRLDGLCRITVKEAENNDTVVRGRAL
IAAGNHHLLLKRSGARYYVEIKDGPLVSRHRPSVDVLFRSAARYAGKNAVGVIMTGMGDDGAHGMLEMKQAGAVNIAQDE
ASCIVFGMPNEAIKLGGVDLVRPLDAISREVLRLCA
>Mature_356_residues
MVKKKIKVLIVDDSAVVRQTLSEILSSDPQIEVMSTAGDPFIAAERIRHEVPDVITLDVEMPRMDGITFLHKIMSQHPIP
VVMCSSLTEMGSETALKALEYGAVEIIQKPRLGTKTFLEESRVRICDVVKAASQARVRKVSAAPHQVAPKLSADVIMEKP
KSQAMMQTTEKVVVIGASTGGTEALRTFLESLPADSPGIVIVQHMPEGFTRAFSQRLDGLCRITVKEAENNDTVVRGRAL
IAAGNHHLLLKRSGARYYVEIKDGPLVSRHRPSVDVLFRSAARYAGKNAVGVIMTGMGDDGAHGMLEMKQAGAVNIAQDE
ASCIVFGMPNEAIKLGGVDLVRPLDAISREVLRLCA

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=348, Percent_Identity=52.5862068965517, Blast_Score=356, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 38598; Mature: 38598

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKKKIKVLIVDDSAVVRQTLSEILSSDPQIEVMSTAGDPFIAAERIRHEVPDVITLDVE
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEE
MPRMDGITFLHKIMSQHPIPVVMCSSLTEMGSETALKALEYGAVEIIQKPRLGTKTFLEE
CCCCCCHHHHHHHHHCCCCCEEEHHHHHHHCHHHHHHHHHHCHHHHHHCCCCCHHHHHHH
SRVRICDVVKAASQARVRKVSAAPHQVAPKLSADVIMEKPKSQAMMQTTEKVVVIGASTG
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHCCCHHHHHHHCCCEEEEEECCCC
GTEALRTFLESLPADSPGIVIVQHMPEGFTRAFSQRLDGLCRITVKEAENNDTVVRGRAL
CHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCCEEEECEEE
IAAGNHHLLLKRSGARYYVEIKDGPLVSRHRPSVDVLFRSAARYAGKNAVGVIMTGMGDD
EEECCEEEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCC
GAHGMLEMKQAGAVNIAQDEASCIVFGMPNEAIKLGGVDLVRPLDAISREVLRLCA
CCCCHHHHHCCCCEEEECCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKKKIKVLIVDDSAVVRQTLSEILSSDPQIEVMSTAGDPFIAAERIRHEVPDVITLDVE
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEE
MPRMDGITFLHKIMSQHPIPVVMCSSLTEMGSETALKALEYGAVEIIQKPRLGTKTFLEE
CCCCCCHHHHHHHHHCCCCCEEEHHHHHHHCHHHHHHHHHHCHHHHHHCCCCCHHHHHHH
SRVRICDVVKAASQARVRKVSAAPHQVAPKLSADVIMEKPKSQAMMQTTEKVVVIGASTG
HHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHCCCHHHHHHHCCCEEEEEECCCC
GTEALRTFLESLPADSPGIVIVQHMPEGFTRAFSQRLDGLCRITVKEAENNDTVVRGRAL
CHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCCEEEECEEE
IAAGNHHLLLKRSGARYYVEIKDGPLVSRHRPSVDVLFRSAARYAGKNAVGVIMTGMGDD
EEECCEEEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCC
GAHGMLEMKQAGAVNIAQDEASCIVFGMPNEAIKLGGVDLVRPLDAISREVLRLCA
CCCCHHHHHCCCCEEEECCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA