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The map label for this gene is modF [H]

Identifier: 197117957

GI number: 197117957

Start: 1818915

End: 1820372

Strand: Direct

Name: modF [H]

Synonym: Gbem_1570

Alternate gene names: 197117957

Gene position: 1818915-1820372 (Clockwise)

Preceding gene: 197117956

Following gene: 197117965

Centisome position: 39.41

GC content: 60.56

Gene sequence:

>1458_bases
GTGAATATCGTTTTGCAGGACGCAGTAGCCAAGATACACAACGGGAAAAACCTGGAAGGGATCACCTTCAACATTGAAGC
GGACGAGCAATGGGCCATCATCGGGGCCAACGGTTCGGGGAAATCGGCGCTGGGGAAACTCCTCTGCGGCGAACTGAAGG
TCGCTTCCGGCATCTGCCGCATCCCGGCCAAAGCCGGGTACGTCTCCTTCGAGAAGATCGACGAGCTCCTGGAAACGGAA
CGCTACAACGACGACTCCGACTTTCTCGGTTACGTCACCCAAGGCACACCGGTGGCCAAGTTCATCCTCTCCGGCTCCCA
GGCCGACGAGGCGACGCTGCTCGAACTCGCCCAGGAGATGGAGTTCACCGGCATCCTGGAGCGGGGCATCAAGTTCCTCT
CCACCGGAGAGATGCGCAAGGTCTTGATCTGCAAATCCCTGTTGCTGGAACCGGAGCTGCTTGTGCTGGACGAGCCGTTC
GACGGGTTGGACCAGCATTCCTGCGAAGTGCTGCGCACCCTTATCAGCCGCTGCATCGGGCGCGGCATCCGGGTGATCCT
GCTCCTGAACCGCTTCAGCGAGATCGTCCCCGAAATCACGCACGTGGCTTACCTGAAAGAGTGCCGCATCTTCATGAGCG
GCACCAAGAACGGGATGCTCGATTCCGAGGCGCTGCGCCGGTTCCACGCCTTTCATTACACCCTTCCCGATCGGTTACCG
GAGATAGATTGCGCGCACCGCCCTGAGCCGCTTCCGGCTGGGGTGCCGCTAGTCGAGATGAAGGACGTGAAAGTCTCTTA
CGGCGGGAAACCGATTCTGTCCGGGCTTTCCTGGACCGTATCGCCCGGGGAGCACTGGAAGATAACGGGGCCGAACGGCT
CGGGGAAATCCACTTTGCTGAGCCTCGTCAGCGGGGACAACACCCAGGCCTACGCCAACGACATCGCTCTTTTCGGCAGG
AAGCGGGGGACCGGCGAGACGGTCTGGGACATCAAGAAGCGGATCGGTTTGGTTTCCACTACGCTGCAGCAGGATTACCG
GGTAGGTGGTTCCGCCAAGATGGTGGTTATCTCCGGATTCTTCGACTCCATCGGCGTCTATTCAGACCCTTCCCCCAGGC
AGCTCGAAATCGCCCAGGAATGGCTGGAACTGCTGCACATGAACCACCGCGCCGGCGACACCTTCCGCGAGCTCTCTTAC
GGCGAGCAGAGGCTGGTACTTTTGGCCCGGGCTATGGTGAAGCAGCCGGACCTGTTGATCCTGGATGAACCGTGCCAGGG
ACTGGACGACGTGAACCGGGAGATGGTGCTGAAGCTGGTGGATCACCTGGGAAGGACGGGGGACACCCAGATCCTCTACG
TGAACCATCACTCCGAGGACCGGATTCCCTGCATCGCCAACCACATGGAACTGGTCCCCGCCGCAGGCGGCGGCTACACC
GGCAAGATCGTCCATTGA

Upstream 100 bases:

>100_bases
AGCCAGTCCCCTCCTTCGGGAAAGGGCTCTAAGGTGGGAAACACCTACCGACTAAGCATCAAGACGCCGCAAGTGCGGCG
AATAAATATCGGATGGAACA

Downstream 100 bases:

>100_bases
GATAGACGCGGTTCATTCCGTTTCCAGCTCTCCCCCTCCCTTGACGGGAGGGGGAGACACTTCGTTCGAGCACCGGCCTC
AAATGAAGCAACGGGTGAGA

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNIVLQDAVAKIHNGKNLEGITFNIEADEQWAIIGANGSGKSALGKLLCGELKVASGICRIPAKAGYVSFEKIDELLETE
RYNDDSDFLGYVTQGTPVAKFILSGSQADEATLLELAQEMEFTGILERGIKFLSTGEMRKVLICKSLLLEPELLVLDEPF
DGLDQHSCEVLRTLISRCIGRGIRVILLLNRFSEIVPEITHVAYLKECRIFMSGTKNGMLDSEALRRFHAFHYTLPDRLP
EIDCAHRPEPLPAGVPLVEMKDVKVSYGGKPILSGLSWTVSPGEHWKITGPNGSGKSTLLSLVSGDNTQAYANDIALFGR
KRGTGETVWDIKKRIGLVSTTLQQDYRVGGSAKMVVISGFFDSIGVYSDPSPRQLEIAQEWLELLHMNHRAGDTFRELSY
GEQRLVLLARAMVKQPDLLILDEPCQGLDDVNREMVLKLVDHLGRTGDTQILYVNHHSEDRIPCIANHMELVPAAGGGYT
GKIVH

Sequences:

>Translated_485_residues
MNIVLQDAVAKIHNGKNLEGITFNIEADEQWAIIGANGSGKSALGKLLCGELKVASGICRIPAKAGYVSFEKIDELLETE
RYNDDSDFLGYVTQGTPVAKFILSGSQADEATLLELAQEMEFTGILERGIKFLSTGEMRKVLICKSLLLEPELLVLDEPF
DGLDQHSCEVLRTLISRCIGRGIRVILLLNRFSEIVPEITHVAYLKECRIFMSGTKNGMLDSEALRRFHAFHYTLPDRLP
EIDCAHRPEPLPAGVPLVEMKDVKVSYGGKPILSGLSWTVSPGEHWKITGPNGSGKSTLLSLVSGDNTQAYANDIALFGR
KRGTGETVWDIKKRIGLVSTTLQQDYRVGGSAKMVVISGFFDSIGVYSDPSPRQLEIAQEWLELLHMNHRAGDTFRELSY
GEQRLVLLARAMVKQPDLLILDEPCQGLDDVNREMVLKLVDHLGRTGDTQILYVNHHSEDRIPCIANHMELVPAAGGGYT
GKIVH
>Mature_485_residues
MNIVLQDAVAKIHNGKNLEGITFNIEADEQWAIIGANGSGKSALGKLLCGELKVASGICRIPAKAGYVSFEKIDELLETE
RYNDDSDFLGYVTQGTPVAKFILSGSQADEATLLELAQEMEFTGILERGIKFLSTGEMRKVLICKSLLLEPELLVLDEPF
DGLDQHSCEVLRTLISRCIGRGIRVILLLNRFSEIVPEITHVAYLKECRIFMSGTKNGMLDSEALRRFHAFHYTLPDRLP
EIDCAHRPEPLPAGVPLVEMKDVKVSYGGKPILSGLSWTVSPGEHWKITGPNGSGKSTLLSLVSGDNTQAYANDIALFGR
KRGTGETVWDIKKRIGLVSTTLQQDYRVGGSAKMVVISGFFDSIGVYSDPSPRQLEIAQEWLELLHMNHRAGDTFRELSY
GEQRLVLLARAMVKQPDLLILDEPCQGLDDVNREMVLKLVDHLGRTGDTQILYVNHHSEDRIPCIANHMELVPAAGGGYT
GKIVH

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI1786975, Length=469, Percent_Identity=43.4968017057569, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI2367384, Length=476, Percent_Identity=24.5798319327731, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994943, Length=484, Percent_Identity=23.3471074380165, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788506, Length=480, Percent_Identity=23.75, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786319, Length=220, Percent_Identity=27.7272727272727, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI48995001, Length=455, Percent_Identity=22.1978021978022, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790190, Length=486, Percent_Identity=22.6337448559671, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786563, Length=227, Percent_Identity=27.3127753303965, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081834, Length=190, Percent_Identity=30.5263157894737, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789873, Length=205, Percent_Identity=31.219512195122, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787029, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787370, Length=205, Percent_Identity=26.3414634146341, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789991, Length=472, Percent_Identity=21.8220338983051, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787712, Length=216, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787112, Length=239, Percent_Identity=28.0334728033473, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320266, Length=501, Percent_Identity=26.5469061876248, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI85725262, Length=260, Percent_Identity=27.6923076923077, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650853, Length=279, Percent_Identity=26.8817204301075, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650855, Length=208, Percent_Identity=29.3269230769231, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 53551; Mature: 53551

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVLQDAVAKIHNGKNLEGITFNIEADEQWAIIGANGSGKSALGKLLCGELKVASGICR
CCEEHHHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEE
IPAKAGYVSFEKIDELLETERYNDDSDFLGYVTQGTPVAKFILSGSQADEATLLELAQEM
CCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHH
EFTGILERGIKFLSTGEMRKVLICKSLLLEPELLVLDEPFDGLDQHSCEVLRTLISRCIG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHC
RGIRVILLLNRFSEIVPEITHVAYLKECRIFMSGTKNGMLDSEALRRFHAFHYTLPDRLP
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
EIDCAHRPEPLPAGVPLVEMKDVKVSYGGKPILSGLSWTVSPGEHWKITGPNGSGKSTLL
CCCCCCCCCCCCCCCCEEEEECEEEECCCCHHHCCCEEEECCCCCEEEECCCCCCHHHHH
SLVSGDNTQAYANDIALFGRKRGTGETVWDIKKRIGLVSTTLQQDYRVGGSAKMVVISGF
HHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
FDSIGVYSDPSPRQLEIAQEWLELLHMNHRAGDTFRELSYGEQRLVLLARAMVKQPDLLI
HHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCEEE
LDEPCQGLDDVNREMVLKLVDHLGRTGDTQILYVNHHSEDRIPCIANHMELVPAAGGGYT
ECCCCCCHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHCCCEEEECCCCCCC
GKIVH
CCCCC
>Mature Secondary Structure
MNIVLQDAVAKIHNGKNLEGITFNIEADEQWAIIGANGSGKSALGKLLCGELKVASGICR
CCEEHHHHHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEE
IPAKAGYVSFEKIDELLETERYNDDSDFLGYVTQGTPVAKFILSGSQADEATLLELAQEM
CCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHH
EFTGILERGIKFLSTGEMRKVLICKSLLLEPELLVLDEPFDGLDQHSCEVLRTLISRCIG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHC
RGIRVILLLNRFSEIVPEITHVAYLKECRIFMSGTKNGMLDSEALRRFHAFHYTLPDRLP
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
EIDCAHRPEPLPAGVPLVEMKDVKVSYGGKPILSGLSWTVSPGEHWKITGPNGSGKSTLL
CCCCCCCCCCCCCCCCEEEEECEEEECCCCHHHCCCEEEECCCCCEEEECCCCCCHHHHH
SLVSGDNTQAYANDIALFGRKRGTGETVWDIKKRIGLVSTTLQQDYRVGGSAKMVVISGF
HHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
FDSIGVYSDPSPRQLEIAQEWLELLHMNHRAGDTFRELSYGEQRLVLLARAMVKQPDLLI
HHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCEEE
LDEPCQGLDDVNREMVLKLVDHLGRTGDTQILYVNHHSEDRIPCIANHMELVPAAGGGYT
ECCCCCCHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHCCCEEEECCCCCCC
GKIVH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]