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The map label for this gene is aroQ [H]

Identifier: 197117946

GI number: 197117946

Start: 1808588

End: 1809037

Strand: Direct

Name: aroQ [H]

Synonym: Gbem_1559

Alternate gene names: 197117946

Gene position: 1808588-1809037 (Clockwise)

Preceding gene: 197117945

Following gene: 197117947

Centisome position: 39.19

GC content: 60.67

Gene sequence:

>450_bases
ATGACAAAACCAGACGTGAGGATATTGGTCCTTCACGGACCGAACCTGAACCTGCTCGGCACCCGCGAGCCGGGGGTCTA
CGGCACCACAACGCTAAAGGGGATCAACCAGTCGCTCATGGCGCTTGCCTCTGAGTTCTCGCTGGAGCTGCGCATCCTGC
AGACCAATTCGGAAGGGGCCATGGTCGACGCCATCCAGGGAGCCATGGCGGATTGCCAGGGAATCCTCATCAACCCTGCT
GCCTACACCCATACCAGCGTCGCCATCCGCGACGCCATCGCCGCAGTGGCGCTCCCCGCTGTGGAAGTGCATCTCTCCAA
CGTCCACGCCAGGGAGCCCTTCAGAAGCCACAGTTACATAGCTCCGGTTGCAGTGGGTCAGATCTGCGGATTCGGCGCCA
TCAGCTACCTTTTAGGACTGCGTGCACTCGCGGAGCGGCTGGGAAAATAA

Upstream 100 bases:

>100_bases
ACGACTTCTTCGTGGCGCTCATCATGACCGCCGACGGCAACTTCGGCAAGGGGCGCTACCTCTTGAAACGCGCCGCCCCC
GGTTTTGCGGAGGCGCTGCA

Downstream 100 bases:

>100_bases
GAATTGTCATACGGGCGGGTTTATGGTAATAGACAGAATCTCTGCGGCCAGGGGGTGCCTCGAGCGGGTCGGAGGCGACC
TGCTGCTGGTCACAAACCTC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MTKPDVRILVLHGPNLNLLGTREPGVYGTTTLKGINQSLMALASEFSLELRILQTNSEGAMVDAIQGAMADCQGILINPA
AYTHTSVAIRDAIAAVALPAVEVHLSNVHAREPFRSHSYIAPVAVGQICGFGAISYLLGLRALAERLGK

Sequences:

>Translated_149_residues
MTKPDVRILVLHGPNLNLLGTREPGVYGTTTLKGINQSLMALASEFSLELRILQTNSEGAMVDAIQGAMADCQGILINPA
AYTHTSVAIRDAIAAVALPAVEVHLSNVHAREPFRSHSYIAPVAVGQICGFGAISYLLGLRALAERLGK
>Mature_148_residues
TKPDVRILVLHGPNLNLLGTREPGVYGTTTLKGINQSLMALASEFSLELRILQTNSEGAMVDAIQGAMADCQGILINPAA
YTHTSVAIRDAIAAVALPAVEVHLSNVHAREPFRSHSYIAPVAVGQICGFGAISYLLGLRALAERLGK

Specific function: Catalyzes a trans-dehydration via an enolate intermediate [H]

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001874
- InterPro:   IPR018509
- ProDom:   PD004527 [H]

Pfam domain/function: PF01220 DHquinase_II [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 15774; Mature: 15642

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPDVRILVLHGPNLNLLGTREPGVYGTTTLKGINQSLMALASEFSLELRILQTNSEGA
CCCCCEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
MVDAIQGAMADCQGILINPAAYTHTSVAIRDAIAAVALPAVEVHLSNVHAREPFRSHSYI
HHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEE
APVAVGQICGFGAISYLLGLRALAERLGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKPDVRILVLHGPNLNLLGTREPGVYGTTTLKGINQSLMALASEFSLELRILQTNSEGA
CCCCEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
MVDAIQGAMADCQGILINPAAYTHTSVAIRDAIAAVALPAVEVHLSNVHAREPFRSHSYI
HHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEE
APVAVGQICGFGAISYLLGLRALAERLGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]