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The map label for this gene is yqhT [H]

Identifier: 197117947

GI number: 197117947

Start: 1809060

End: 1810130

Strand: Direct

Name: yqhT [H]

Synonym: Gbem_1560

Alternate gene names: 197117947

Gene position: 1809060-1810130 (Clockwise)

Preceding gene: 197117946

Following gene: 197117948

Centisome position: 39.2

GC content: 63.49

Gene sequence:

>1071_bases
ATGGTAATAGACAGAATCTCTGCGGCCAGGGGGTGCCTCGAGCGGGTCGGAGGCGACCTGCTGCTGGTCACAAACCTCAG
TAATATCAGATACCTTACCGGGTTCACCGGCAGCGAGGCGCTGCTGGTTCTCTCGCCAGACGACGGATGGTTTCTGACCG
ATTCCCGTTACACCTCCCAGGCCGGCGCCGAAGTCACAGGCGCAAGAGTTGCCGAGTTCTCCAACAAGATGGAATCGCTG
GTCGAGTTGCTGCAAAAGCTGCAGCCGTCCAAGGTAGCCTTCGAGGCGGCCCACACCATGGTTGCCGTCTACCTGGAGCT
CTGCAGCAAAACGCCGCAGATCGAATACCTTCCGGCGGACGCCGAGATGACGGCGCTGCGCAGCGTCAAGGACGCCGGCG
AGCTGGAGATCCTGGAAAGGGTGGCCGCGATCGCGTCGGAGTCGCTTTTGGAGACGCTGGCGCGGGTGACCCCCGGCATG
ACCGAGGGCGAGGCCGCCTGGATGCTGGAGGTTGCCATGAGGGAGAGGGGGGCGGAGAACAAGTCCTTCGACTTCATCGT
CGCCTCCGGCGAGCGGGGCGCGCTTCCCCACGGCAAGGCGTCCGGGAAGCGGCTCGCAAAAGGGGAACTGATCACCTTCG
ACTACGGCGCCATCTACGGCGGTTACTGCTCCGATGAGACGGTGACCGTTTCATTGGGCGAGCCGGACAGCCGGCAGCGC
GAGGTCTACGAGACCGTGCTGGGCGCCCAACGCGCCGCCATGAACGCCGTTCACCCGGGGCTGAGCTTCAGGGACCTTGA
CGCTGTGGCAAGGGATTACATCGCCTCGCGCGGCTTTGGCGAGTACTTCGGGCATGGGCTCGGGCACGGCGTGGGCATAG
ATATTCATGAACACCCGGCGGCATCGCCGCGCAGCAAGAACGTGATCCAGGAGGGTATGGTATTCACCATCGAGCCCGGG
ATCTACATCTCGGGATGGGGCGGGGTAAGGATCGAGGACACCGTGGTCGCCGAGTCCCATGGTTGCCGCTGCATCACCAA
GGTCCCCAAGGACCTGATCGTATTGCCGTGA

Upstream 100 bases:

>100_bases
GTGGGTCAGATCTGCGGATTCGGCGCCATCAGCTACCTTTTAGGACTGCGTGCACTCGCGGAGCGGCTGGGAAAATAAGA
ATTGTCATACGGGCGGGTTT

Downstream 100 bases:

>100_bases
CCGTTTTCAAGCAGACTGCACCCGATGCGCTCCGGGGCAGTCTTTTAATCATGCAGTTAGCGTAAATGCAAAGGAGATAG
ATGTGGATATAAAAGACCTG

Product: prolidase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MVIDRISAARGCLERVGGDLLLVTNLSNIRYLTGFTGSEALLVLSPDDGWFLTDSRYTSQAGAEVTGARVAEFSNKMESL
VELLQKLQPSKVAFEAAHTMVAVYLELCSKTPQIEYLPADAEMTALRSVKDAGELEILERVAAIASESLLETLARVTPGM
TEGEAAWMLEVAMRERGAENKSFDFIVASGERGALPHGKASGKRLAKGELITFDYGAIYGGYCSDETVTVSLGEPDSRQR
EVYETVLGAQRAAMNAVHPGLSFRDLDAVARDYIASRGFGEYFGHGLGHGVGIDIHEHPAASPRSKNVIQEGMVFTIEPG
IYISGWGGVRIEDTVVAESHGCRCITKVPKDLIVLP

Sequences:

>Translated_356_residues
MVIDRISAARGCLERVGGDLLLVTNLSNIRYLTGFTGSEALLVLSPDDGWFLTDSRYTSQAGAEVTGARVAEFSNKMESL
VELLQKLQPSKVAFEAAHTMVAVYLELCSKTPQIEYLPADAEMTALRSVKDAGELEILERVAAIASESLLETLARVTPGM
TEGEAAWMLEVAMRERGAENKSFDFIVASGERGALPHGKASGKRLAKGELITFDYGAIYGGYCSDETVTVSLGEPDSRQR
EVYETVLGAQRAAMNAVHPGLSFRDLDAVARDYIASRGFGEYFGHGLGHGVGIDIHEHPAASPRSKNVIQEGMVFTIEPG
IYISGWGGVRIEDTVVAESHGCRCITKVPKDLIVLP
>Mature_356_residues
MVIDRISAARGCLERVGGDLLLVTNLSNIRYLTGFTGSEALLVLSPDDGWFLTDSRYTSQAGAEVTGARVAEFSNKMESL
VELLQKLQPSKVAFEAAHTMVAVYLELCSKTPQIEYLPADAEMTALRSVKDAGELEILERVAAIASESLLETLARVTPGM
TEGEAAWMLEVAMRERGAENKSFDFIVASGERGALPHGKASGKRLAKGELITFDYGAIYGGYCSDETVTVSLGEPDSRQR
EVYETVLGAQRAAMNAVHPGLSFRDLDAVARDYIASRGFGEYFGHGLGHGVGIDIHEHPAASPRSKNVIQEGMVFTIEPG
IYISGWGGVRIEDTVVAESHGCRCITKVPKDLIVLP

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI260593665, Length=294, Percent_Identity=30.2721088435374, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI149589008, Length=294, Percent_Identity=29.9319727891156, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI11559925, Length=239, Percent_Identity=30.5439330543933, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI93141226, Length=299, Percent_Identity=27.4247491638796, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI260593663, Length=238, Percent_Identity=29.8319327731092, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI264681563, Length=225, Percent_Identity=32, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI164420681, Length=202, Percent_Identity=25.7425742574257, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI264681565, Length=222, Percent_Identity=30.1801801801802, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788728, Length=365, Percent_Identity=37.5342465753425, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1789275, Length=392, Percent_Identity=26.530612244898, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786364, Length=257, Percent_Identity=24.5136186770428, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508215, Length=297, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17509539, Length=226, Percent_Identity=29.646017699115, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321118, Length=298, Percent_Identity=25.1677852348993, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320922, Length=242, Percent_Identity=24.7933884297521, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322999, Length=367, Percent_Identity=21.2534059945504, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920384, Length=265, Percent_Identity=28.6792452830189, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21357079, Length=292, Percent_Identity=26.7123287671233, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38416; Mature: 38416

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIDRISAARGCLERVGGDLLLVTNLSNIRYLTGFTGSEALLVLSPDDGWFLTDSRYTSQ
CCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEECCCCCEEEECCCCCCC
AGAEVTGARVAEFSNKMESLVELLQKLQPSKVAFEAAHTMVAVYLELCSKTPQIEYLPAD
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
AEMTALRSVKDAGELEILERVAAIASESLLETLARVTPGMTEGEAAWMLEVAMRERGAEN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
KSFDFIVASGERGALPHGKASGKRLAKGELITFDYGAIYGGYCSDETVTVSLGEPDSRQR
CCEEEEEECCCCCCCCCCCCCCCEECCCCEEEEECCCEECCCCCCCEEEEECCCCCHHHH
EVYETVLGAQRAAMNAVHPGLSFRDLDAVARDYIASRGFGEYFGHGLGHGVGIDIHEHPA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEECCCCC
ASPRSKNVIQEGMVFTIEPGIYISGWGGVRIEDTVVAESHGCRCITKVPKDLIVLP
CCCCHHHHHHCCCEEEECCCEEEECCCCCEEEEEEEECCCCCEEHCCCCCCEEECC
>Mature Secondary Structure
MVIDRISAARGCLERVGGDLLLVTNLSNIRYLTGFTGSEALLVLSPDDGWFLTDSRYTSQ
CCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEECCCCCEEEECCCCCCC
AGAEVTGARVAEFSNKMESLVELLQKLQPSKVAFEAAHTMVAVYLELCSKTPQIEYLPAD
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
AEMTALRSVKDAGELEILERVAAIASESLLETLARVTPGMTEGEAAWMLEVAMRERGAEN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
KSFDFIVASGERGALPHGKASGKRLAKGELITFDYGAIYGGYCSDETVTVSLGEPDSRQR
CCEEEEEECCCCCCCCCCCCCCCEECCCCEEEEECCCEECCCCCCCEEEEECCCCCHHHH
EVYETVLGAQRAAMNAVHPGLSFRDLDAVARDYIASRGFGEYFGHGLGHGVGIDIHEHPA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEECCCCC
ASPRSKNVIQEGMVFTIEPGIYISGWGGVRIEDTVVAESHGCRCITKVPKDLIVLP
CCCCHHHHHHCCCEEEECCCEEEECCCCCEEEEEEEECCCCCEEHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]