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The map label for this gene is aroB-1

Identifier: 197117943

GI number: 197117943

Start: 1805977

End: 1807065

Strand: Direct

Name: aroB-1

Synonym: Gbem_1556

Alternate gene names: 197117943

Gene position: 1805977-1807065 (Clockwise)

Preceding gene: 197117942

Following gene: 197117944

Centisome position: 39.13

GC content: 63.09

Gene sequence:

>1089_bases
GTGATAGCTGAAAAGATCAGGGTCGCGCTTGACGAACGGAGTTACGACATCGAAATGGGCGCCGGCAATCTCGACAGAAT
CGGTTCCCTTTGCCGCGAAGTCGGCCTGTCCGGAACGGCGGCGGTGGTCAGCAACACCACCGTGGCCCCGCTCTATTACG
AAACTGTCAGGCTCTCCATGGAGCGCGCAGGGTACCGGGTGGTGCCGGTAACTCTCCCGGACGGTGAGGGGTACAAGAAC
AGCGCTACGTTGAACCTGATCTACGACGGCCTGGTAGACGCCTCGCTCGACCGCGGCTCCTTCATCCTGGCCTTAGGCGG
CGGGGTCATCGGCGACATGGCCGGGTTCGCCGCCGCAAGTTACCTGCGCGGCATCCCCTTCGTCCAAATTCCCACCACGC
TTCTCTCCCAGGTCGACTCCAGTGTCGGCGGCAAGACCGGCATCAACCATCCCCGCGGCAAGAACCTGATCGGCGCCTTC
TACCAGCCCAAAGCGGTCCTCATCGACGTCGCCACCCTCGATACCCTCCCGAAAAGGGAGTTCCTGAGCGGTCTGGGAGA
GATCGTCAAGTACGGTGCGGTGCTGGACGGCGGCTTTTTCGATTTCCTGGAAAAAAACGCGAAACTGCTATTGGCCCGCG
ACAAGGAGGCCCTGATCCAGGCGGTCAGCCGCAGCTGCGCCATCAAGGCGAAGGTCGTGGCGGAGGACGAACGGGAAGGT
GGGGTGCGCGCCGTGCTGAACTACGGGCACACCCTGGGGCACGCCGTGGAGACCCTCACCGGTTACACCCGCTACCTGCA
CGGGGAGGCGGTCGCTATCGGCATGGTACAGGCTGCGCGGCTCTCCCAGCACTACGGCTTCTGCTCCCAGGCGGATCGGG
AGCGCATCGAGGCCCTGGTCGTGGCGCTGGGGCTGCCGACAGAACTTCCTTCCTTCCCGCCTCAGCAGTACAGGGAGGCG
CTCTCGCACGACAAGAAGGTACGCGACAAGGGACTCTTGTTCATCTGCAACCAGGGGATTGGTGCCTACCGCATGGAAAG
GCTCACCGACCTGGGGGCGCTTCTGGAGATCTGTGGCATAGGAGAATGA

Upstream 100 bases:

>100_bases
GCGAAGAGTATTATGCCGACGCCGACCTGCGCATCGACACCACGGGCAAGACCATAGAGGCGGTGGCCTCGGAAGTAATC
GACTCTTTGAAGGGGTTTTT

Downstream 100 bases:

>100_bases
CATGGTAGAGGACGCTTTATCCTTCTGGACGGAGATACAGCGCTACGAGGACATGCTGGCAACCGATGCCAAGAACTTGT
GCTTCGCGCCCCTCTCGGAG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MIAEKIRVALDERSYDIEMGAGNLDRIGSLCREVGLSGTAAVVSNTTVAPLYYETVRLSMERAGYRVVPVTLPDGEGYKN
SATLNLIYDGLVDASLDRGSFILALGGGVIGDMAGFAAASYLRGIPFVQIPTTLLSQVDSSVGGKTGINHPRGKNLIGAF
YQPKAVLIDVATLDTLPKREFLSGLGEIVKYGAVLDGGFFDFLEKNAKLLLARDKEALIQAVSRSCAIKAKVVAEDEREG
GVRAVLNYGHTLGHAVETLTGYTRYLHGEAVAIGMVQAARLSQHYGFCSQADRERIEALVVALGLPTELPSFPPQQYREA
LSHDKKVRDKGLLFICNQGIGAYRMERLTDLGALLEICGIGE

Sequences:

>Translated_362_residues
MIAEKIRVALDERSYDIEMGAGNLDRIGSLCREVGLSGTAAVVSNTTVAPLYYETVRLSMERAGYRVVPVTLPDGEGYKN
SATLNLIYDGLVDASLDRGSFILALGGGVIGDMAGFAAASYLRGIPFVQIPTTLLSQVDSSVGGKTGINHPRGKNLIGAF
YQPKAVLIDVATLDTLPKREFLSGLGEIVKYGAVLDGGFFDFLEKNAKLLLARDKEALIQAVSRSCAIKAKVVAEDEREG
GVRAVLNYGHTLGHAVETLTGYTRYLHGEAVAIGMVQAARLSQHYGFCSQADRERIEALVVALGLPTELPSFPPQQYREA
LSHDKKVRDKGLLFICNQGIGAYRMERLTDLGALLEICGIGE
>Mature_362_residues
MIAEKIRVALDERSYDIEMGAGNLDRIGSLCREVGLSGTAAVVSNTTVAPLYYETVRLSMERAGYRVVPVTLPDGEGYKN
SATLNLIYDGLVDASLDRGSFILALGGGVIGDMAGFAAASYLRGIPFVQIPTTLLSQVDSSVGGKTGINHPRGKNLIGAF
YQPKAVLIDVATLDTLPKREFLSGLGEIVKYGAVLDGGFFDFLEKNAKLLLARDKEALIQAVSRSCAIKAKVVAEDEREG
GVRAVLNYGHTLGHAVETLTGYTRYLHGEAVAIGMVQAARLSQHYGFCSQADRERIEALVVALGLPTELPSFPPQQYREA
LSHDKKVRDKGLLFICNQGIGAYRMERLTDLGALLEICGIGE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=339, Percent_Identity=49.8525073746313, Blast_Score=302, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6320332, Length=321, Percent_Identity=37.6947040498442, Blast_Score=213, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_GEOBB (B5E8I9)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002138370.1
- ProteinModelPortal:   B5E8I9
- SMR:   B5E8I9
- GeneID:   6781544
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_1556
- HOGENOM:   HBG632303
- OMA:   GWIDESI
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38928; Mature: 38928

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAEKIRVALDERSYDIEMGAGNLDRIGSLCREVGLSGTAAVVSNTTVAPLYYETVRLSM
CCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHCCCEECHHHHHHHHHHH
ERAGYRVVPVTLPDGEGYKNSATLNLIYDGLVDASLDRGSFILALGGGVIGDMAGFAAAS
HHCCCEEEEEECCCCCCCCCCCEEEEEECCHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
YLRGIPFVQIPTTLLSQVDSSVGGKTGINHPRGKNLIGAFYQPKAVLIDVATLDTLPKRE
HHCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEEEEHHHCCCCHHH
FLSGLGEIVKYGAVLDGGFFDFLEKNAKLLLARDKEALIQAVSRSCAIKAKVVAEDEREG
HHHHHHHHHHHCCHHCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHCEEEEEEECCCCCC
GVRAVLNYGHTLGHAVETLTGYTRYLHGEAVAIGMVQAARLSQHYGFCSQADRERIEALV
CHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VALGLPTELPSFPPQQYREALSHDKKVRDKGLLFICNQGIGAYRMERLTDLGALLEICGI
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCC
GE
CC
>Mature Secondary Structure
MIAEKIRVALDERSYDIEMGAGNLDRIGSLCREVGLSGTAAVVSNTTVAPLYYETVRLSM
CCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHCCCEECHHHHHHHHHHH
ERAGYRVVPVTLPDGEGYKNSATLNLIYDGLVDASLDRGSFILALGGGVIGDMAGFAAAS
HHCCCEEEEEECCCCCCCCCCCEEEEEECCHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
YLRGIPFVQIPTTLLSQVDSSVGGKTGINHPRGKNLIGAFYQPKAVLIDVATLDTLPKRE
HHCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEEEEHHHCCCCHHH
FLSGLGEIVKYGAVLDGGFFDFLEKNAKLLLARDKEALIQAVSRSCAIKAKVVAEDEREG
HHHHHHHHHHHCCHHCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHCEEEEEEECCCCCC
GVRAVLNYGHTLGHAVETLTGYTRYLHGEAVAIGMVQAARLSQHYGFCSQADRERIEALV
CHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VALGLPTELPSFPPQQYREALSHDKKVRDKGLLFICNQGIGAYRMERLTDLGALLEICGI
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCC
GE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA