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The map label for this gene is tkt [H]

Identifier: 197117767

GI number: 197117767

Start: 1593655

End: 1595790

Strand: Direct

Name: tkt [H]

Synonym: Gbem_1379

Alternate gene names: 197117767

Gene position: 1593655-1595790 (Clockwise)

Preceding gene: 197117766

Following gene: 197117768

Centisome position: 34.53

GC content: 69.24

Gene sequence:

>2136_bases
ATGACCATCGAATTAAATCCGGGCAGCGCCGGGAACCTGGACCAGCTCTGCATCAACACCTTGCGTTTCCTGGCGGTGGA
CGCCATCCAAGAAGCCAACAGTGGCCATCCCGGCATGCCGATGGGGGCAGCCCCCATGGCATACCTGCTCTGGACCCGAT
TCCTGAGGCACAATCCCGCCTCCCCGGGTTGGTTCGACCGGGACCGCTTCGTCCTCTCCGCGGGGCATGGCTCCATGCTG
CTTTACTCCCTGCTGCACCTGACCGGCTACGACCTCCCCCTGTCGGAGCTGAAACGCTTCCGACAGTGGGGAAGCCGCAC
CCCCGGACACCCGGAGCGGGGGCTTACTCCGGGGGTAGAGCTGACCACCGGGCCTTTGGGGCAGGGGTTCGCCGGCGCCG
TCGGCATGGCGATAGCAGAATCCCATCTTGCCGCCCGCTATAACCGGCCGGGGTTCACGCTCGTGGACCACTTCACCTAC
GCCCTTGTCGGTGACGGCGACCTCATGGAAGGGGTGGCGGCCGAGGCGGCCTCGCTTGCCGGGCACCTGCGCCTTGCAAA
GCTCATCTGCCTATACGACGACAACCGCATCACGCTCGCCGCCGCAACCGATCTGAGCTTCACCGAGGACCGCGGCGCGC
GCTTCAGGGCCTACGGCTGGCAGGTGCTCGAGGTTGCCGACGGCAACGATCCGGAGGCGATCGGGTGGGCCTTGGAGGAG
GCGCGGGCGGAAAAAGAGCGCCCCTCCCTGGTCATGGTGCGCACCCGGATCGGGTTCGGCTCGCCGCAGAAACAGGACAG
CTTCGAGGCGCACGGCGCACCCCTTGGGGTGGAGGAGGTGCGCCGCACCAAGGATGCGCTCGGATGGCCGCAGGAGCCGC
AGTTCCACATCCCGCCCGAGGCGCTGGCGCGGTTTCGCGAGGCGCTGGTGAAAGGCGCCGTGGAGGAGCGGGCCTGGGAG
TCGGTCATGGCGGGTTACGACGCGGCGTACCCGGCTGAGAGCGCCGAACTGACGCAGGTTCTGGCTGGGGAGCTGCCGCA
GGGGTGGCAGGAGGCTCTGCCGGAATTCCCCGCCGACGCCAAGGGGATGGCGACGCGGGTAGCCTCGGCAAAGGTGCTGA
ACGCCTTGGCCCAGAGGGTGCCGCAACTTTTCGGCGGCTCCGCCGACTTGAACCCCTCGACGCTCACCGCGCTCGCCGGC
AAGGGCGACTTCCAGCCCGAAAGCTTCGACCCGCTGGACAGGCAGGGGGCGGTGGGGGGGGCATGGGGGCGCGCCGGGGC
GAACCTGCACTTCGGCGTCCGCGAGCACGCCATGGGGGCCATCCTGAACGGAATGGCGGCGCACGGCGGCACGCTTCCCT
ACGGCGCCACCTTCCTCACCTTCTCCGATTATCTCCGCCCCGTGCTCAGGCTGGCGGCGCTGTCGCGGCTCAAGGTGATC
CACATCTTCACCCACGACTCCATAGCGCTGGGGGAGGACGGGCCGACCCACCAGCCGGTGGAACAGCTGGCTTCCCTGCG
CGCCATCCCGCGCCTGGTGGTATTTAGGCCTGGGGACGCCAACGAGTGCGTTGAGGCCTGGCGCGCGGCGCTCCAGGTCG
AGGGGCGGCCGGTGGCCCTCGTGCTCTCGCGCCAGGCGCTGCCCACTTTGGACCGTGGGGAGCTGGGCGCGGCGGCGGGG
GTGCTCCGGGGAGGCTACGTCCTCGCCGAGGCGCGGCAGGGGGCGCCTCGCCTGATCCTCATCGCCACTGGATCCGAGCT
TTCCCTGGCCCTGGCTGCGCGCAATTCGCTTGAGGAGCGCGGCCTCGCGGTCCGCGTCGTCTCTCTCCCCAGTTGGGAGC
TCTTCGACGAGCAGCCGCAGGAGTACCGGGACTTCGTGCTGCCGCCTACGATGACGGCGCGGCTGGCGATCGAGGCGGGG
GCGACCCAGGGATGGCACCGCTACCTGGGGTCGGGGGGGATAGTCTTGGGAGTCGACGATTTCGGGGCCTCTGCCCCGGG
AGAGGTCGTCTTGAGGGAGTATGGTTTCACCGTGGACCATGTTTGTGGCATGGCGCTGCAATTGACAGGGGGCGCGGGCC
CCGGCCTGGGCGCGGCGCCCGAAAAACCGCCGGAGGCACCCTCTCCGAAACCGTAG

Upstream 100 bases:

>100_bases
TCTTTGCTCCATCACTTGCTATAGTGGCTCGGGGCGGCAGCGCCAGGGAAACACCTTGGCCCCCCCACAACCCCACAACT
TCATGTGAAGGAGCAGCGCC

Downstream 100 bases:

>100_bases
GAGCGAGACATGAGAGAAACGCCGCTTACCAACCTGGTGCAGTGCGGACAGAGCGTCTGGCTCGACGGCATCAGCCGTCC
CATGCTGCTCTCCGGGGCCC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 711; Mature: 710

Protein sequence:

>711_residues
MTIELNPGSAGNLDQLCINTLRFLAVDAIQEANSGHPGMPMGAAPMAYLLWTRFLRHNPASPGWFDRDRFVLSAGHGSML
LYSLLHLTGYDLPLSELKRFRQWGSRTPGHPERGLTPGVELTTGPLGQGFAGAVGMAIAESHLAARYNRPGFTLVDHFTY
ALVGDGDLMEGVAAEAASLAGHLRLAKLICLYDDNRITLAAATDLSFTEDRGARFRAYGWQVLEVADGNDPEAIGWALEE
ARAEKERPSLVMVRTRIGFGSPQKQDSFEAHGAPLGVEEVRRTKDALGWPQEPQFHIPPEALARFREALVKGAVEERAWE
SVMAGYDAAYPAESAELTQVLAGELPQGWQEALPEFPADAKGMATRVASAKVLNALAQRVPQLFGGSADLNPSTLTALAG
KGDFQPESFDPLDRQGAVGGAWGRAGANLHFGVREHAMGAILNGMAAHGGTLPYGATFLTFSDYLRPVLRLAALSRLKVI
HIFTHDSIALGEDGPTHQPVEQLASLRAIPRLVVFRPGDANECVEAWRAALQVEGRPVALVLSRQALPTLDRGELGAAAG
VLRGGYVLAEARQGAPRLILIATGSELSLALAARNSLEERGLAVRVVSLPSWELFDEQPQEYRDFVLPPTMTARLAIEAG
ATQGWHRYLGSGGIVLGVDDFGASAPGEVVLREYGFTVDHVCGMALQLTGGAGPGLGAAPEKPPEAPSPKP

Sequences:

>Translated_711_residues
MTIELNPGSAGNLDQLCINTLRFLAVDAIQEANSGHPGMPMGAAPMAYLLWTRFLRHNPASPGWFDRDRFVLSAGHGSML
LYSLLHLTGYDLPLSELKRFRQWGSRTPGHPERGLTPGVELTTGPLGQGFAGAVGMAIAESHLAARYNRPGFTLVDHFTY
ALVGDGDLMEGVAAEAASLAGHLRLAKLICLYDDNRITLAAATDLSFTEDRGARFRAYGWQVLEVADGNDPEAIGWALEE
ARAEKERPSLVMVRTRIGFGSPQKQDSFEAHGAPLGVEEVRRTKDALGWPQEPQFHIPPEALARFREALVKGAVEERAWE
SVMAGYDAAYPAESAELTQVLAGELPQGWQEALPEFPADAKGMATRVASAKVLNALAQRVPQLFGGSADLNPSTLTALAG
KGDFQPESFDPLDRQGAVGGAWGRAGANLHFGVREHAMGAILNGMAAHGGTLPYGATFLTFSDYLRPVLRLAALSRLKVI
HIFTHDSIALGEDGPTHQPVEQLASLRAIPRLVVFRPGDANECVEAWRAALQVEGRPVALVLSRQALPTLDRGELGAAAG
VLRGGYVLAEARQGAPRLILIATGSELSLALAARNSLEERGLAVRVVSLPSWELFDEQPQEYRDFVLPPTMTARLAIEAG
ATQGWHRYLGSGGIVLGVDDFGASAPGEVVLREYGFTVDHVCGMALQLTGGAGPGLGAAPEKPPEAPSPKP
>Mature_710_residues
TIELNPGSAGNLDQLCINTLRFLAVDAIQEANSGHPGMPMGAAPMAYLLWTRFLRHNPASPGWFDRDRFVLSAGHGSMLL
YSLLHLTGYDLPLSELKRFRQWGSRTPGHPERGLTPGVELTTGPLGQGFAGAVGMAIAESHLAARYNRPGFTLVDHFTYA
LVGDGDLMEGVAAEAASLAGHLRLAKLICLYDDNRITLAAATDLSFTEDRGARFRAYGWQVLEVADGNDPEAIGWALEEA
RAEKERPSLVMVRTRIGFGSPQKQDSFEAHGAPLGVEEVRRTKDALGWPQEPQFHIPPEALARFREALVKGAVEERAWES
VMAGYDAAYPAESAELTQVLAGELPQGWQEALPEFPADAKGMATRVASAKVLNALAQRVPQLFGGSADLNPSTLTALAGK
GDFQPESFDPLDRQGAVGGAWGRAGANLHFGVREHAMGAILNGMAAHGGTLPYGATFLTFSDYLRPVLRLAALSRLKVIH
IFTHDSIALGEDGPTHQPVEQLASLRAIPRLVVFRPGDANECVEAWRAALQVEGRPVALVLSRQALPTLDRGELGAAAGV
LRGGYVLAEARQGAPRLILIATGSELSLALAARNSLEERGLAVRVVSLPSWELFDEQPQEYRDFVLPPTMTARLAIEAGA
TQGWHRYLGSGGIVLGVDDFGASAPGEVVLREYGFTVDHVCGMALQLTGGAGPGLGAAPEKPPEAPSPKP

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=599, Percent_Identity=25.7095158597663, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI4507521, Length=599, Percent_Identity=25.7095158597663, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI133778974, Length=598, Percent_Identity=26.2541806020067, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI225637459, Length=635, Percent_Identity=22.6771653543307, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI225637463, Length=562, Percent_Identity=23.1316725978648, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI225637461, Length=562, Percent_Identity=23.1316725978648, Blast_Score=105, Evalue=2e-22,
Organism=Escherichia coli, GI48994911, Length=674, Percent_Identity=50.1483679525223, Blast_Score=659, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=679, Percent_Identity=49.4845360824742, Blast_Score=637, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=590, Percent_Identity=26.1016949152542, Blast_Score=158, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6325331, Length=674, Percent_Identity=46.2908011869436, Blast_Score=604, Evalue=1e-173,
Organism=Saccharomyces cerevisiae, GI6319593, Length=678, Percent_Identity=44.9852507374631, Blast_Score=570, Evalue=1e-163,
Organism=Drosophila melanogaster, GI45551847, Length=674, Percent_Identity=26.1127596439169, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI45550715, Length=674, Percent_Identity=26.1127596439169, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24645119, Length=646, Percent_Identity=25.8513931888545, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24666278, Length=592, Percent_Identity=25.6756756756757, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 76005; Mature: 75874

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIELNPGSAGNLDQLCINTLRFLAVDAIQEANSGHPGMPMGAAPMAYLLWTRFLRHNPA
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
SPGWFDRDRFVLSAGHGSMLLYSLLHLTGYDLPLSELKRFRQWGSRTPGHPERGLTPGVE
CCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCE
LTTGPLGQGFAGAVGMAIAESHLAARYNRPGFTLVDHFTYALVGDGDLMEGVAAEAASLA
EECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEECCCHHHHHHHHHHHHHH
GHLRLAKLICLYDDNRITLAAATDLSFTEDRGARFRAYGWQVLEVADGNDPEAIGWALEE
HHHHEEEEEEEEECCEEEEEEECCCCCCCCCCCEEEECCEEEEEECCCCCCHHHHHHHHH
ARAEKERPSLVMVRTRIGFGSPQKQDSFEAHGAPLGVEEVRRTKDALGWPQEPQFHIPPE
HHHHHCCCCEEEEEEECCCCCCCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHH
ALARFREALVKGAVEERAWESVMAGYDAAYPAESAELTQVLAGELPQGWQEALPEFPADA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCC
KGMATRVASAKVLNALAQRVPQLFGGSADLNPSTLTALAGKGDFQPESFDPLDRQGAVGG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCCCCCCCCCCCCCCCCCC
AWGRAGANLHFGVREHAMGAILNGMAAHGGTLPYGATFLTFSDYLRPVLRLAALSRLKVI
CCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEE
HIFTHDSIALGEDGPTHQPVEQLASLRAIPRLVVFRPGDANECVEAWRAALQVEGRPVAL
EEEECCCEEECCCCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEE
VLSRQALPTLDRGELGAAAGVLRGGYVLAEARQGAPRLILIATGSELSLALAARNSLEER
EEECCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCEEEEEECCCCCEEHHHHHHHHHHC
GLAVRVVSLPSWELFDEQPQEYRDFVLPPTMTARLAIEAGATQGWHRYLGSGGIVLGVDD
CCEEEEEECCCHHHHCCCCHHHHCCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEEEECC
FGASAPGEVVLREYGFTVDHVCGMALQLTGGAGPGLGAAPEKPPEAPSPKP
CCCCCCHHHHHHHHCCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIELNPGSAGNLDQLCINTLRFLAVDAIQEANSGHPGMPMGAAPMAYLLWTRFLRHNPA
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
SPGWFDRDRFVLSAGHGSMLLYSLLHLTGYDLPLSELKRFRQWGSRTPGHPERGLTPGVE
CCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCE
LTTGPLGQGFAGAVGMAIAESHLAARYNRPGFTLVDHFTYALVGDGDLMEGVAAEAASLA
EECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEECCCHHHHHHHHHHHHHH
GHLRLAKLICLYDDNRITLAAATDLSFTEDRGARFRAYGWQVLEVADGNDPEAIGWALEE
HHHHEEEEEEEEECCEEEEEEECCCCCCCCCCCEEEECCEEEEEECCCCCCHHHHHHHHH
ARAEKERPSLVMVRTRIGFGSPQKQDSFEAHGAPLGVEEVRRTKDALGWPQEPQFHIPPE
HHHHHCCCCEEEEEEECCCCCCCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHH
ALARFREALVKGAVEERAWESVMAGYDAAYPAESAELTQVLAGELPQGWQEALPEFPADA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCC
KGMATRVASAKVLNALAQRVPQLFGGSADLNPSTLTALAGKGDFQPESFDPLDRQGAVGG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCCCCCCCCCCCCCCCCCC
AWGRAGANLHFGVREHAMGAILNGMAAHGGTLPYGATFLTFSDYLRPVLRLAALSRLKVI
CCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEE
HIFTHDSIALGEDGPTHQPVEQLASLRAIPRLVVFRPGDANECVEAWRAALQVEGRPVAL
EEEECCCEEECCCCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEE
VLSRQALPTLDRGELGAAAGVLRGGYVLAEARQGAPRLILIATGSELSLALAARNSLEER
EEECCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCEEEEEECCCCCEEHHHHHHHHHHC
GLAVRVVSLPSWELFDEQPQEYRDFVLPPTMTARLAIEAGATQGWHRYLGSGGIVLGVDD
CCEEEEEECCCHHHHCCCCHHHHCCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEEEECC
FGASAPGEVVLREYGFTVDHVCGMALQLTGGAGPGLGAAPEKPPEAPSPKP
CCCCCCHHHHHHHHCCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]